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Best Biotech Stocks

Quick Read: Best Biotech Stocks List By Performances & Trends:
Daily, Weekly, Year-to-Date, Market Cap (Size) & Technical Trends
Best Biotech Stocks Views: Quick Browse View, Summary & Slide Show View

12Stocks.com Biotech Stocks Performances & Trends Daily
September 18, 2025 - All trends (long term, mid-term and short term) for Biotech sector looks good.

The overall market intelligence score is 80 (0-bearish to 100-bullish) which puts Biotech sector in short term neutral to bullish trend.

The market intelligence score from previous trading session is 60 and hence an improvement of trend.

 Year To Date Performance: 4.23268 %
 Weekly Performance: 1.58679 %
 Daily Performance: 1.72763 %
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Biotech Sector Trend
80 / 100
Here are the market intelligence trend scores of the most requested Biotech stocks at 12Stocks.com (click stock name for detailed review):

12Stocks.com: Investing in Biotech sector with Stocks
The following table helps investors and traders sort through current performance and trends (as measured by market intelligence score) of various stocks in the Biotech sector.

Quick View: Move mouse or cursor over stock symbol (ticker) to view short-term Technical chart and over stock name to view long term chart. Click on to add stock symbol to your watchlist and to view watchlist. Click on any ticker or stock name for detailed market intelligence report for that stock.

12Stocks.com Performance of Stocks in Biotech Sector

TickerStock NameWatchlistCategoryRecent PriceMarket Intelligence ScoreChange %YTD Change%
IDYAIdeaya  Biotechnology24.4430-1.13-2.86%
KROSKeros  Biotechnology15.6270-1.14-1.88%
IMCRImmunocore  Biotechnology33.4140-1.1512.06%
IMMPImmutep  Biotechnology1.6760-1.18-24.43%
IMVTImmunovant  Biotechnology15.1130-1.18-40.02%
ALDXAldeyra  Biotechnology4.9030-1.21-6.13%
SRRKScholar Rock Biotechnology31.9550-1.21-27.65%
EWTXEdgewise  Biotechnology13.8920-1.21-48.61%
PRTAProthena  Biotechnology8.0630-1.23-41.04%
VIRVir nology Biotechnology4.8010-1.23-33.98%
OCXOncoCyte  Biotechnology3.1650-1.2535.62%
KODKodiak  Biotechnology9.2150-1.296.84%
TARAProtara  Biotechnology3.030-1.30-45.70%
KYMRKymera  Biotechnology48.1290-1.3517.68%
ZGNXZogenix  Biotechnology2.880-1.370.00%
REPLReplimune  Biotechnology5.7120-1.38-54.54%
AVROAVROBIO  Biotechnology1.4010-1.410.00%
DMACDiaMedica  Biotechnology6.8760-1.4324.68%
COGTCogent  Biotechnology12.3650-1.4458.46%
IPHAInnate Pharma Biotechnology2.0550-1.449.63%
SEERSeer  Biotechnology2.0640-1.44-11.59%
CGENCompugen  Biotechnology1.3610-1.45-17.58%
OCSOculis Holding Biotechnology17.4050-1.472.78%
DNLIDenali  Biotechnology13.0620-1.51-37.33%
CTMXCytomX  Biotechnology1.930-1.5382.08%
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Click To Change The Sort Order: By Market Cap or Company Size
Performance: Year-to-date, Week and Day
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Detailed Overview of Biotech Stocks
Biotech Technical Overview, Leaders & Laggards, Top Biotech ETF Funds & Detailed Biotech Stocks List, Charts, Trends & More

Biotech Sector: Technical Analysis, Trends & YTD Performance
Biotech sector, as represented by XBI, an exchange-traded fund [ETF] that holds basket of Biotech stocks (e.g, Amgen, Celgene) is up by 4.23268% and is currently underperforming the overall market by -9.35602% year-to-date. Below is a quick view of Technical charts and trends:

XBI Weekly Chart
Long Term Trend: Very Good
Medium Term Trend: Very Good

XBI Daily Chart
Short Term Trend: Very Good
Overall Trend Score: 80
YTD Performance: 4.23268%
**Trend Scores & Views Are Only For Educational Purposes And Not For Investing


12Stocks.com: Top Performing Biotech Sector Stocks
Hot Biotech Stocks of 2025 We try to spot trends by analyzing the performances of various stocks or components within Biotech sector and try to find best performing stocks. The movers and shakers. The winners and losers.

The top performing Biotech sector stocks year to date are
Celcuity [316%] I-Mab ADR[307%] Galectin [292%]
Immuneering Corp[265%] Nektar [254%] Precigen [254%]
Nanobiotix ADR[252%] Gossamer Bio[208%] DBV Technologies[203%]
Monopar [200%] ATAI Life[194%]
View complete list of Biotech stocks by year-to-date performance

Now, more recently, over last week, the top performing Biotech sector stocks on the move are
Athersys [193287%] VBI Vaccines[86898.5%] ContraFect [47677.8%]
Clovis Oncology[39610.5%] NanoString Technologies[17224.7%] Neptune Wellness[14100%]
Achillion [10033.3%] Nymox [8258.5%] Epizyme [5739.5%]
Portola [4717.6%] Strongbridge Biopharma[3417.5%]
View complete list of Biotech stocks by weekly performance

Unfortunately not all Biotech stocks have done well this year. Investors of these stocks hope they have seen the worst and hope that these stocks are set to bounce back. The bearish stocks in this index year to date (YTD) are
Vaxxinity [-100%] Petros [-100%] Translate Bio[-95%]
Palatin Technologies[-93%] Syros [-91%] Pliant [-89%]
Affimed N.V[-87%] Unity nology[-86%] Sarepta [-85%]
IGM [-80%] Rocket [-76%] Allakos [-73%]
.
Investors can get enhanced performance by riding the current stock trends. Using complex algorithms, 12Stocks.com has come up with market intelligence scores (on 0-bearish to 100-bullish scale) to identify best trending stocks. Top trending Biotech stocks are
AlloVir [100] Monopar [100] Cara [100]
Corbus [100] Ocugen [100] Spruce [100]
Roivant [100] Xencor [100] Oncolytics [100]
Tango [100] Arcus [100] RAPT [100]
View complete list of Biotech stocks by 12Stocks.com trends

12Stocks.com: Investing in Biotech Sector using Exchange Traded Funds
The following table shows list of key exchange traded funds (ETF) that help investors track Biotech Index. For detailed view, check out our ETF Funds section of our website.

Quick View: Move mouse or cursor over ETF symbol (ticker) to view short-term Technical chart and over ETF name to view long term chart. Click on ticker or stock name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist.

12Stocks.com List of ETFs that track Biotech Index

TickerETF NameWatchlistRecent PriceMarket Intelligence ScoreChange %Week %Year-to-date %
UBIOBiotechnology  73.3480-0.0681292260.7480%
HCRFEdge Multifactor 67.142309999NA
SICKHealthcare Bear 3X 37.903609999NA
LABSBiotech Bear 1X 24.185609999NA
BTECPrincipal Healthcare Innovators 39.493001.023280%
 Market Intelligence Score (0-Bearish to 100-Bullish)
12Stocks.com: Charts, Trends, Fundamental Data and Performances of Biotech Stocks
We now take in-depth look at all Biotech stocks including charts, multi-period performances and overall trends (as measured by market intelligence score).

One can sort Biotech stocks (click link to choose) by Daily, Weekly and by Year-to-Date performances. Also, one can sort by size of the company or by market capitalization.
Select Your Default Chart Type:
Long Term Chart Daily Chart Weekly Chart 
Long Term Chart (Default)
Weekly Chart Example
Daily Chart Example
Click on stock symbol or name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist. Quick View: Move mouse or cursor over "Daily" to quickly view daily Technical stock chart and over "Weekly" to view weekly Technical stock chart.

Stock Chart of Ideaya Biosciences IncIDYA Ideaya Biosciences Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 2380.4 Millions
Recent Price: 24.44    
Market Intelligence Score: 30
Day Percent Change: -1.13269%    
Day Change: 0.31
Week Change: -1.21261%    
Year-to-date Change: -2.9%
IDYA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add IDYA to Watchlist:       View:      Get Complete IDYA Trend Analysis ➞

Stock Chart of Keros Therapeutics IncKROS Keros Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 633.19 Millions
Recent Price: 15.62    
Market Intelligence Score: 70
Day Percent Change: -1.13924%    
Day Change: 0.94
Week Change: -0.572883%    
Year-to-date Change: -1.9%
KROS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add KROS to Watchlist:       View:      Get Complete KROS Trend Analysis ➞

Stock Chart of Immunocore Holdings plc ADRIMCR Immunocore Holdings plc ADR
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1873.76 Millions
Recent Price: 33.41    
Market Intelligence Score: 40
Day Percent Change: -1.15368%    
Day Change: 0.18
Week Change: -8.67723%    
Year-to-date Change: 12.1%
IMCR Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add IMCR to Watchlist:       View:      Get Complete IMCR Trend Analysis ➞

Stock Chart of Immutep Limited ADRIMMP Immutep Limited ADR
Sector: Health Care
SubSector: Biotechnology
MarketCap: 242.2 Millions
Recent Price: 1.67    
Market Intelligence Score: 60
Day Percent Change: -1.18343%    
Day Change: -0.02
Week Change: 4.375%    
Year-to-date Change: -24.4%
IMMP Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add IMMP to Watchlist:       View:      Get Complete IMMP Trend Analysis ➞

Stock Chart of Immunovant IncIMVT Immunovant Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 2987.79 Millions
Recent Price: 15.11    
Market Intelligence Score: 30
Day Percent Change: -1.17724%    
Day Change: 0.02
Week Change: -7.86585%    
Year-to-date Change: -40.0%
IMVT Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add IMVT to Watchlist:       View:      Get Complete IMVT Trend Analysis ➞

Stock Chart of Aldeyra Therapeutics IncALDX Aldeyra Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 333.02 Millions
Recent Price: 4.90    
Market Intelligence Score: 30
Day Percent Change: -1.20968%    
Day Change: 0.25
Week Change: -14.9306%    
Year-to-date Change: -6.1%
ALDX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ALDX to Watchlist:       View:      Get Complete ALDX Trend Analysis ➞

Stock Chart of Scholar Rock Holding CorpSRRK Scholar Rock Holding Corp
Sector: Health Care
SubSector: Biotechnology
MarketCap: 3019.36 Millions
Recent Price: 31.95    
Market Intelligence Score: 50
Day Percent Change: -1.20594%    
Day Change: 0.19
Week Change: 1.17163%    
Year-to-date Change: -27.6%
SRRK Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add SRRK to Watchlist:       View:      Get Complete SRRK Trend Analysis ➞

Stock Chart of Edgewise Therapeutics IncEWTX Edgewise Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1640.23 Millions
Recent Price: 13.89    
Market Intelligence Score: 20
Day Percent Change: -1.2091%    
Day Change: 0.78
Week Change: -5.83051%    
Year-to-date Change: -48.6%
EWTX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add EWTX to Watchlist:       View:      Get Complete EWTX Trend Analysis ➞

Stock Chart of Prothena Corporation plcPRTA Prothena Corporation plc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 460.25 Millions
Recent Price: 8.06    
Market Intelligence Score: 30
Day Percent Change: -1.22549%    
Day Change: 0.04
Week Change: -3.35731%    
Year-to-date Change: -41.0%
PRTA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PRTA to Watchlist:       View:      Get Complete PRTA Trend Analysis ➞

Stock Chart of Vir Biotechnology IncVIR Vir Biotechnology Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 732.09 Millions
Recent Price: 4.80    
Market Intelligence Score: 10
Day Percent Change: -1.23457%    
Day Change: 0.02
Week Change: -8.39695%    
Year-to-date Change: -34.0%
VIR Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add VIR to Watchlist:       View:      Get Complete VIR Trend Analysis ➞

Stock Chart of OncoCyte CorporationOCX OncoCyte Corporation
Sector: Health Care
SubSector: Biotechnology
MarketCap: 131.485 Millions
Recent Price: 3.16    
Market Intelligence Score: 50
Day Percent Change: -1.25%    
Day Change: -9999
Week Change: 14.7005%    
Year-to-date Change: 35.6%
OCX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add OCX to Watchlist:       View:      Get Complete OCX Trend Analysis ➞

Stock Chart of Kodiak Sciences IncKOD Kodiak Sciences Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 555.68 Millions
Recent Price: 9.21    
Market Intelligence Score: 50
Day Percent Change: -1.28617%    
Day Change: 0.21
Week Change: -8.4493%    
Year-to-date Change: 6.8%
KOD Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add KOD to Watchlist:       View:      Get Complete KOD Trend Analysis ➞

Stock Chart of Protara Therapeutics IncTARA Protara Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 121.53 Millions
Recent Price: 3.03    
Market Intelligence Score: 0
Day Percent Change: -1.30293%    
Day Change: 0.07
Week Change: -2.57235%    
Year-to-date Change: -45.7%
TARA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add TARA to Watchlist:       View:      Get Complete TARA Trend Analysis ➞

Stock Chart of Kymera Therapeutics IncKYMR Kymera Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 3110.86 Millions
Recent Price: 48.12    
Market Intelligence Score: 90
Day Percent Change: -1.35301%    
Day Change: 0.24
Week Change: 10.6716%    
Year-to-date Change: 17.7%
KYMR Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add KYMR to Watchlist:       View:      Get Complete KYMR Trend Analysis ➞

Stock Chart of Zogenix, Inc.ZGNX Zogenix, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1143.75 Millions
Recent Price: 2.88    
Market Intelligence Score: 0
Day Percent Change: -1.36986%    
Day Change: -9999
Week Change: -89.2054%    
Year-to-date Change: 0.0%
ZGNX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ZGNX to Watchlist:       View:      Get Complete ZGNX Trend Analysis ➞

Stock Chart of Replimune Group IncREPL Replimune Group Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 494.09 Millions
Recent Price: 5.71    
Market Intelligence Score: 20
Day Percent Change: -1.38169%    
Day Change: 0.35
Week Change: -1.89003%    
Year-to-date Change: -54.5%
REPL Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add REPL to Watchlist:       View:      Get Complete REPL Trend Analysis ➞

Stock Chart of AVROBIO, Inc.AVRO AVROBIO, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 626.185 Millions
Recent Price: 1.40    
Market Intelligence Score: 10
Day Percent Change: -1.40845%    
Day Change: -9999
Week Change: -6.04027%    
Year-to-date Change: 0.0%
AVRO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add AVRO to Watchlist:       View:      Get Complete AVRO Trend Analysis ➞

Stock Chart of DiaMedica Therapeutics IncDMAC DiaMedica Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 317.37 Millions
Recent Price: 6.87    
Market Intelligence Score: 60
Day Percent Change: -1.43472%    
Day Change: -0.07
Week Change: -4.71567%    
Year-to-date Change: 24.7%
DMAC Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add DMAC to Watchlist:       View:      Get Complete DMAC Trend Analysis ➞

Stock Chart of Cogent Biosciences IncCOGT Cogent Biosciences Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1823.1 Millions
Recent Price: 12.36    
Market Intelligence Score: 50
Day Percent Change: -1.43541%    
Day Change: -0.09
Week Change: -3.58814%    
Year-to-date Change: 58.5%
COGT Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add COGT to Watchlist:       View:      Get Complete COGT Trend Analysis ➞

Stock Chart of Innate Pharma ADRIPHA Innate Pharma ADR
Sector: Health Care
SubSector: Biotechnology
MarketCap: 188.92 Millions
Recent Price: 2.05    
Market Intelligence Score: 50
Day Percent Change: -1.44231%    
Day Change: 0
Week Change: 0.244499%    
Year-to-date Change: 9.6%
IPHA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add IPHA to Watchlist:       View:      Get Complete IPHA Trend Analysis ➞

Stock Chart of Seer IncSEER Seer Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 118.31 Millions
Recent Price: 2.06    
Market Intelligence Score: 40
Day Percent Change: -1.43541%    
Day Change: 0
Week Change: 1.9802%    
Year-to-date Change: -11.6%
SEER Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add SEER to Watchlist:       View:      Get Complete SEER Trend Analysis ➞

Stock Chart of Compugen LtdCGEN Compugen Ltd
Sector: Health Care
SubSector: Biotechnology
MarketCap: 133.76 Millions
Recent Price: 1.36    
Market Intelligence Score: 10
Day Percent Change: -1.44928%    
Day Change: -0.01
Week Change: -4.8951%    
Year-to-date Change: -17.6%
CGEN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CGEN to Watchlist:       View:      Get Complete CGEN Trend Analysis ➞

Stock Chart of Oculis Holding AGOCS Oculis Holding AG
Sector: Health Care
SubSector: Biotechnology
MarketCap: 939.07 Millions
Recent Price: 17.40    
Market Intelligence Score: 50
Day Percent Change: -1.47225%    
Day Change: 0.25
Week Change: 1.22164%    
Year-to-date Change: 2.8%
OCS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add OCS to Watchlist:       View:      Get Complete OCS Trend Analysis ➞

Stock Chart of Denali Therapeutics IncDNLI Denali Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 2256.06 Millions
Recent Price: 13.06    
Market Intelligence Score: 20
Day Percent Change: -1.5083%    
Day Change: 0.72
Week Change: -14.974%    
Year-to-date Change: -37.3%
DNLI Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add DNLI to Watchlist:       View:      Get Complete DNLI Trend Analysis ➞

Stock Chart of CytomX Therapeutics IncCTMX CytomX Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 376 Millions
Recent Price: 1.93    
Market Intelligence Score: 0
Day Percent Change: -1.53061%    
Day Change: 0.06
Week Change: -7.6555%    
Year-to-date Change: 82.1%
CTMX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CTMX to Watchlist:       View:      Get Complete CTMX Trend Analysis ➞

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Click To Change The Sort Order: By Market Cap or Company Size
Performance: Year-to-date, Week and Day
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