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Stock Charts, Performance & Trend Analysis for XBI
SPDR Biotech

XBI
Year-to-Date: 13.2%
This Week: 8.1%
XBI Stock Charts
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XBI
Year-to-Date (YTD) Return: 13.2038%
 
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Long Term Trend: Very Good
Medium Term Trend: Very Good
Short Term Trend: Very Good
Biotech
Overall Trend Score:
100 Out Of 100
Bottomline: Bullish Trend


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October 4, 2025 - The year-to-date (YTD) performance of Biotech (XBI) ETF is up 13.2038% but is underperforming the overall stock market by -1.6167%.

Recently, the weekly returns of Biotech (XBI) is up 8.07428% and is outperforming the overall market by 6.58877%.

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All trends (long term, mid-term and short term) for SPDR Biotech looks good.

The overall 12Stocks.com Smart Investing & Trading Score is 100 (measures stock trend from 0-bearish to 100-bullish) which puts XBI in short term bullish trend.

The Smart Investing & Trading Score from previous trading session is 90 and an improvement of trend continues. Scroll down for key technical charts, support & resistance levels and analysis for Biotech.

Stock Analysis for XBI
Name: SPDR Biotech
Sector:
SubSector:
In A Glance
XBI Technical Trend Chart View

Daily XBI Technical Chart
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Short Term Trend Analysis for
100 / 100
The current technical trend score is 100 in a scale where 0 is bearish and 100 is bullish.
The technical trend score from previous session is 100.
Trend score updated daily. Not to be used for investing.
Recent Price: 103.60    
MarketCap: Millions
Day Percent Change: 0.984501%
Day Change: 0.94
Week Change: 8.07428%
Year-to-date Change: 13.2038%

Technical Levels: For the trading inclined, the following are the key levels of resistance (ceiling) and support (floor) for XBI. Ceiling and floor levels are stock prices at which the stock trend gets resistance or support respectively and traders have an eye on them. Long term levels are more important. Stocks that have broken thru their resistance or supports convincingly tend to have stronger trends (confirm with charts above visually).
Key Levels for XBI
 Short TermWeeklyLong Term
Resistance (Ceiling)
Support (Floor)

The table below shows stocks similar to SPDR Biotech, i.e, from same subsector or sector along with year-to-date (YTD), weekly & daily performaces for comparison. Usually, stocks from similar sector tend to move together but companies that have innovative products, services or good management tend to outperform. Quick View: Move mouse or cursor over stock symbol (ticker) to view short-term technical chart and over stock name to view long term chart. Click on ticker or stock name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist.
TickerStock NameWatchlistCategoryRecent PriceChange %Weekly Change%YTD Change%
VRTXVertex Pharmaceuticals, Inc Biotechnology403.30-1.357475.61186-0.60627%
CELGCelgene Corporation Biotechnology55.131.30467-27.74570%
PSTXPoseida Therapeutics, Inc. Biotechnology9.50-0.6276150.8492571.06383%
REGNRegeneron Pharmaceuticals, Inc Biotechnology600.0008.00886-15.8742%
ALNYAlnylam Pharmaceuticals Inc Biotechnology456.35-1.006531.5058595.3386%
INZYInozyme Pharma, Inc. Biotechnology4.0000.25062740.3509%
SPRBSpruce Biosciences, Inc. Biotechnology11.3912.493839.3272-63.7895%
ARGXArgen X SE ADR Biotechnology800.001.0624212.503328.999%
ONCBeOne Medicines Ltd ADR Biotechnology338.55-1.923.830%
INSMInsmed Inc Biotechnology157.182.8664915.923124.703%
BNTXBioNTech SE ADR Biotechnology105.001.508127.05546-8.93322%
ALVRAlloVir, Inc. Biotechnology11.4716.921520.864110.8213%
CERECerevel Therapeutics Holdings, Inc. Biotechnology44.9603.666130%
PTPIPetros Pharmaceuticals, Inc. Biotechnology0.03-4.7619-6.66667-99.7604%
RPRXRoyalty Pharma plc Biotechnology36.07-1.1513.3524441.7311%
ALXNAlexion Pharmaceuticals, Inc. Biotechnology834.361.90781357.1840%
SMMTSummit Therapeutics Inc Biotechnology21.432.683285.7749316.7847%
SGENSeattle Genetics, Inc. Biotechnology202.141.63407-8.781590%
KRONKronos Bio, Inc. Biotechnology0.881.487720.89429-9.2877%
GMABGenmab ADR Biotechnology33.213.3935215.152658.1429%
INCYIncyte Corp Biotechnology86.850.660646.3556224.9101%
ASNDAscendis Pharma A/S ADR Biotechnology203.951.558617.489247.7899%
BMRNBiomarin Pharmaceutical Inc Biotechnology55.44-0.2339395.35918-16.619%
BGNEBeiGene, Ltd. Biotechnology184.710.4896364.651560%
BBIOBridgeBio Pharma Inc Biotechnology52.86-0.7882887.8775587.4468%
LLYLilly(Eli) & Co Drugs839.872.4419117.53178.35033%
JNJJohnson & Johnson Drugs188.641.430266.1385233.1602%
ABBVAbbvie Inc Drugs233.91-1.120227.0330433.9476%
UNHUnitedhealth Group Inc Insurance360.201.831964.2366-27.7899%
AZNAstrazeneca plc ADR Drugs85.301.9713116.005732.1852%
NVSNovartis AG ADR Drugs132.391.084228.312241.1945%
ABTAbbott Laboratories Instrument134.591.20310.96016820.3566%
MRKMerck & Co Inc Drugs89.19-0.35750214.9356-8.37827%
TMOThermo Fisher Scientific Inc Health Services543.323.4974118.31374.16651%
NVONovo Nordisk ADR Drugs59.631.515156.40614-30.7691%
ISRGIntuitive Surgical Inc Instrument452.322.102663.24226-13.6834%
BSXBoston Scientific Corp Instrument97.321.14321-0.8355418.88342%
AMGNAMGEN Inc Drugs297.890.1647619.8495516.843%
SYKStryker Corp Instrument370.501.1190.5236453.74403%
DHRDanaher Corp Health Services214.992.2155718.4779-6.15724%
GILDGilead Sciences, Inc Drugs112.691.926561.5316724.3868%
PFEPfizer Inc Drugs27.371.070915.97468.3896%
MDTMedtronic Plc Instrument97.702.325093.6055123.7755%
SNYSanofi ADR Drugs50.891.4755712.913210.2823%
VRTXVertex Pharmaceuticals, Inc Biotechnology403.30-1.357475.61186-0.60627%
CELGCelgene Corporation Biotechnology55.131.30467-27.74570%
HCAHCA Healthcare Inc Health Services429.540.6679323.5310644.8687%
BMYBristol-Myers Squibb Co Drugs45.45-0.612294.69938-17.1292%
CVSCVS Health Corp Insurance77.490.05164623.8600781.2496%
MCKMckesson Corporation Health Services738.06-2.720440.20909130.6245%
You can find complete coverage in the following
Related Pages: 2025 Best Performing Stocks, 2025 Best Performing ETF Funds

Technical Levels: For the trading inclined, the following are the key levels of resistance (ceiling) and support (floor) for XBI. Ceiling and floor levels are stock prices at which the stock trend gets resistance or support respectively. Stocks & their trends tend to pause at these levels and hence traders have an eye on them.

Long term levels are more important. Stocks that have broken thru their resistance or support levels convincingly tend to have stronger trends (confirm with charts above visually).
Key Technical Levels for XBI
 Short TermWeeklyLong Term
Resistance (Ceiling)
Support (Floor)

        
RELATIVE PERFORMANCE OF
SPDR Biotech
Vs
THE MARKET
Relative performance of SPDR Biotech
How is XBI faring versus the market [S&P 500] ? Is it lagging or leading ? How is its relative performance ?
Symbol Day Change Week Change Year-to-Date Change
VTI 0.0545802% 1.48551% 14.8205%
XBI 0.984501% 8.07428% 13.2038%

XBI Daily Chart
Total Market Daily Chart
Year to date returns XBI is underperforming the market by -1.6167%
This week, XBI is outperforming the market by 6.58877%


List Of ETF Funds Similar To SPDR Biotech

The table below shows ETFs (Exchange Traded Funds) similar to SPDR Biotech, i.e, from same sector along with year-to-date (YTD), weekly & daily performaces for comparison. Usually, ETFs and associated stocks from similar sector tend to move together but companies that have innovative products, services or good management tend to outperform. Move mouse or cursor over ETF symbol to view short-term technical chart and over ETF name to view long term chart. Click on to add ETF symbol to your watchlist and to view watchlist.
TickerStock NameWatchlistCategoryRecent PriceChange %Weekly Change%YTD Change%
BBHBiotech HOLDRs Health Care174.881.302798.6049811.3595%
IBBiShares Nasdaq Biotechnology Health Care151.000.9223378.5784113.7117%
PBEPowerShares Biotech  Health Care72.710.9697267.160358.62393%
XBISPDR Biotech Health Care103.600.9845018.0742813.2038%
PPHPharmaceutical HOLDRs Health Care94.050.7822559.3731810.3223%
RXLProShares Ultra HealthCare  Health Care45.932.2136216.11755.25751%
RXDProShares UltraShort HealthCare  Health Care10.41-2.18572-14.3501-12.5277%
XLVHealth Care SPDR Health Care144.821.138357.969886.15123%
IHFiShares U. S. Healthcare Providers Health Care50.651.462344.282486.2268%
IXJiShares Global Healthcare  Health Care92.631.146548.275868.64083%
IYHiShares US Healthcare Health Care61.161.208018.075635.42247%
PJPPowerShares Pharmaceuticals Health Care95.651.32356.0307115.998%
VHTVanguard Health Care VIPERS Health Care269.571.136797.703066.89121%
IHIiShares U.S. Medical Devices Health Care60.631.134282.260084.11247%
IHEiShares U.S. Pharmaceuticals Health Care75.611.367489.4369716.2344%
PTHPowerShares Dyn Healthcare Health Care44.770.1837196.3951110.2438%
XPHPharmaceuticals SPDR Health Care49.001.512336.940215.5895%
HHRHealthShares Respiratory-Pulmonary Health Care15.03000%
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