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Best Biotech Stocks

Quick Read: Best Biotech Stocks List By Performances & Trends:
Daily, Weekly, Year-to-Date, Market Cap (Size) & Technical Trends
Best Biotech Stocks Views: Quick Browse View, Summary & Slide Show View

12Stocks.com Biotech Stocks Performances & Trends Daily
September 18, 2025 - Although long and mid term trends for Biotech sector looks good, the short term trends are deteriorating.

The overall market intelligence score is 60 (0-bearish to 100-bullish) which puts Biotech sector in short term neutral to bullish trend.

The market intelligence score from previous trading session is 70 and a deterioration of trend continues.

 Year To Date Performance: 2.46251 %
 Weekly Performance: -1.27395 %
 Daily Performance: 0.0320034 %
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Biotech Sector Trend
60 / 100
Here are the market intelligence trend scores of the most requested Biotech stocks at 12Stocks.com (click stock name for detailed review):

12Stocks.com: Investing in Biotech sector with Stocks
The following table helps investors and traders sort through current performance and trends (as measured by market intelligence score) of various stocks in the Biotech sector.

Quick View: Move mouse or cursor over stock symbol (ticker) to view short-term Technical chart and over stock name to view long term chart. Click on to add stock symbol to your watchlist and to view watchlist. Click on any ticker or stock name for detailed market intelligence report for that stock.

12Stocks.com Performance of Stocks in Biotech Sector

TickerStock NameWatchlistCategoryRecent PriceMarket Intelligence ScoreChange %YTD Change%
VRTXVertex  Biotechnology387.1510-1.08%-4.59%
CELGCelgene  Biotechnology55.13201.30%0.00%
PSTXPoseida  Biotechnology9.5050-0.63%1.06%
REGNRegeneron  Biotechnology585.501001.82%-17.91%
ALNYAlnylam  Biotechnology451.7340-2.06%93.36%
INZYInozyme Pharma Biotechnology4.00500.00%40.35%
SPRBSpruce  Biotechnology11.3910012.49%-63.79%
ARGXArgen X Biotechnology734.3540-2.39%18.41%
INSMInsmed  Biotechnology144.78400.02%106.98%
BNTXBioNTech SE Biotechnology98.1540-1.12%-14.87%
ALVRAlloVir  Biotechnology11.4710016.92%10.82%
CERECerevel  Biotechnology44.96500.00%0.00%
PTPIPetros  Biotechnology0.030-4.76%-99.76%
RPRXRoyalty Pharma Biotechnology35.64300.62%40.04%
ALXNAlexion  Biotechnology834.36901.91%0.00%
SMMTSummit  Biotechnology18.0930-0.17%-1.42%
SGENSeattle Genetics Biotechnology202.14301.63%0.00%
KRONKronos Bio Biotechnology0.88401.49%-9.29%
GMABGenmab ADR Biotechnology28.0890-0.57%33.71%
INCYyte Corp Biotechnology84.80801.07%21.96%
ASNDAscendis Pharma Biotechnology199.59901.19%44.63%
BMRNBiomarin  Biotechnology54.37500.80%-18.23%
BGNEBeiGene  Biotechnology184.71400.49%0.00%
BBIOBridgeBio Pharma Biotechnology51.1860-0.60%81.49%
EXELExelixis  Biotechnology40.44803.32%19.15%
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Performance: Year-to-date, Week and Day
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Detailed Overview of Biotech Stocks
Biotech Technical Overview, Leaders & Laggards, Top Biotech ETF Funds & Detailed Biotech Stocks List, Charts, Trends & More

Biotech Sector: Technical Analysis, Trends & YTD Performance
Biotech sector, as represented by XBI, an exchange-traded fund [ETF] that holds basket of Biotech stocks (e.g, Amgen, Celgene) is up by 2.46251% and is currently underperforming the overall market by -10.68429% year-to-date. Below is a quick view of Technical charts and trends:

XBI Weekly Chart
Long Term Trend: Very Good
Medium Term Trend: Very Good

XBI Daily Chart
Short Term Trend: Not Good
Overall Trend Score: 60
YTD Performance: 2.46251%
**Trend Scores & Views Are Only For Educational Purposes And Not For Investing


12Stocks.com: Top Performing Biotech Sector Stocks
Hot Biotech Stocks of 2025 We try to spot trends by analyzing the performances of various stocks or components within Biotech sector and try to find best performing stocks. The movers and shakers. The winners and losers.

The top performing Biotech sector stocks year to date are
Celcuity [316%] I-Mab ADR[307%] Galectin [292%]
Immuneering Corp[265%] Nektar [254%] Precigen [254%]
Nanobiotix ADR[252%] Gossamer Bio[208%] DBV Technologies[203%]
Monopar [200%] ATAI Life[194%]
View complete list of Biotech stocks by year-to-date performance

Now, more recently, over last week, the top performing Biotech sector stocks on the move are
Athersys [193287%] VBI Vaccines[86898.5%] ContraFect [47677.8%]
Clovis Oncology[39610.5%] NanoString Technologies[17224.7%] Neptune Wellness[14100%]
Achillion [10033.3%] Nymox [8258.5%] Epizyme [5739.5%]
Portola [4717.6%] Strongbridge Biopharma[3417.5%]
View complete list of Biotech stocks by weekly performance

Unfortunately not all Biotech stocks have done well this year. Investors of these stocks hope they have seen the worst and hope that these stocks are set to bounce back. The bearish stocks in this index year to date (YTD) are
Vaxxinity [-100%] Petros [-100%] Translate Bio[-95%]
Palatin Technologies[-93%] Syros [-91%] Pliant [-88%]
Affimed N.V[-87%] Sarepta [-86%] Unity nology[-86%]
IGM [-80%] Rocket [-76%] Allakos [-73%]
.
Investors can get enhanced performance by riding the current stock trends. Using complex algorithms, 12Stocks.com has come up with market intelligence scores (on 0-bearish to 100-bullish scale) to identify best trending stocks. Top trending Biotech stocks are
AlloVir [100] Monopar [100] Cara [100]
Corbus [100] Spruce [100] Ocugen [100]
Roivant [100] Xencor [100] Oncolytics [100]
Tango [100] Arcus [100] Regeneron [100]
View complete list of Biotech stocks by 12Stocks.com trends

12Stocks.com: Investing in Biotech Sector using Exchange Traded Funds
The following table shows list of key exchange traded funds (ETF) that help investors track Biotech Index. For detailed view, check out our ETF Funds section of our website.

Quick View: Move mouse or cursor over ETF symbol (ticker) to view short-term Technical chart and over ETF name to view long term chart. Click on ticker or stock name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist.

12Stocks.com List of ETFs that track Biotech Index

TickerETF NameWatchlistRecent PriceMarket Intelligence ScoreChange %Week %Year-to-date %
UBIOBiotechnology  73.3480-0.0681292260.7480%
HCRFEdge Multifactor 67.142309999NA
SICKHealthcare Bear 3X 37.903609999NA
LABSBiotech Bear 1X 24.185609999NA
BTECPrincipal Healthcare Innovators 39.493001.023280%
 Market Intelligence Score (0-Bearish to 100-Bullish)
12Stocks.com: Charts, Trends, Fundamental Data and Performances of Biotech Stocks
We now take in-depth look at all Biotech stocks including charts, multi-period performances and overall trends (as measured by market intelligence score).

One can sort Biotech stocks (click link to choose) by Daily, Weekly and by Year-to-Date performances. Also, one can sort by size of the company or by market capitalization.
Select Your Default Chart Type:
Long Term Chart Daily Chart Weekly Chart 
Long Term Chart (Default)
Weekly Chart Example
Daily Chart Example
Click on stock symbol or name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist. Quick View: Move mouse or cursor over "Daily" to quickly view daily Technical stock chart and over "Weekly" to view weekly Technical stock chart.

Stock Chart of Vertex Pharmaceuticals, IncVRTX Vertex Pharmaceuticals, Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 101561 Millions
Recent Price: 387.15    
Market Intelligence Score: 10
Day Percent Change: -1.07574%    
Day Change: -2.75
Week Change: -2.35321%    
Year-to-date Change: -4.6%
VRTX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add VRTX to Watchlist:       View:      Get Complete VRTX Trend Analysis ➞

Stock Chart of Celgene CorporationCELG Celgene Corporation
Sector: Health Care
SubSector: Biotechnology
MarketCap: 99608.4 Millions
Recent Price: 55.13    
Market Intelligence Score: 20
Day Percent Change: 1.30467%    
Day Change: -9999
Week Change: -27.7457%    
Year-to-date Change: 0.0%
CELG Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CELG to Watchlist:       View:      Get Complete CELG Trend Analysis ➞

Stock Chart of Poseida Therapeutics, Inc.PSTX Poseida Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 64487 Millions
Recent Price: 9.50    
Market Intelligence Score: 50
Day Percent Change: -0.627615%    
Day Change: -9999
Week Change: 0.849257%    
Year-to-date Change: 1.1%
PSTX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PSTX to Watchlist:       View:      Get Complete PSTX Trend Analysis ➞

Stock Chart of Regeneron Pharmaceuticals, IncREGN Regeneron Pharmaceuticals, Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 60771.1 Millions
Recent Price: 585.50    
Market Intelligence Score: 100
Day Percent Change: 1.81546%    
Day Change: 6.58
Week Change: 5.20547%    
Year-to-date Change: -17.9%
REGN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add REGN to Watchlist:       View:      Get Complete REGN Trend Analysis ➞

Stock Chart of Alnylam Pharmaceuticals IncALNY Alnylam Pharmaceuticals Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 59247.7 Millions
Recent Price: 451.73    
Market Intelligence Score: 40
Day Percent Change: -2.06292%    
Day Change: -4.66
Week Change: -6.30639%    
Year-to-date Change: 93.4%
ALNY Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ALNY to Watchlist:       View:      Get Complete ALNY Trend Analysis ➞

Stock Chart of Inozyme Pharma, Inc.INZY Inozyme Pharma, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 53487 Millions
Recent Price: 4.00    
Market Intelligence Score: 50
Day Percent Change: 0%    
Day Change: -9999
Week Change: 0.250627%    
Year-to-date Change: 40.4%
INZY Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add INZY to Watchlist:       View:      Get Complete INZY Trend Analysis ➞

Stock Chart of Spruce Biosciences, Inc.SPRB Spruce Biosciences, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 49487 Millions
Recent Price: 11.39    
Market Intelligence Score: 100
Day Percent Change: 12.4938%    
Day Change: -9999
Week Change: 39.3272%    
Year-to-date Change: -63.8%
SPRB Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add SPRB to Watchlist:       View:      Get Complete SPRB Trend Analysis ➞

Stock Chart of Argen X SE ADRARGX Argen X SE ADR
Sector: Health Care
SubSector: Biotechnology
MarketCap: 45947.7 Millions
Recent Price: 734.35    
Market Intelligence Score: 40
Day Percent Change: -2.38861%    
Day Change: 2.76
Week Change: -4.25684%    
Year-to-date Change: 18.4%
ARGX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ARGX to Watchlist:       View:      Get Complete ARGX Trend Analysis ➞

Stock Chart of Insmed IncINSM Insmed Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 30670.5 Millions
Recent Price: 144.78    
Market Intelligence Score: 40
Day Percent Change: 0.0207254%    
Day Change: 3.15
Week Change: -1.64402%    
Year-to-date Change: 107.0%
INSM Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add INSM to Watchlist:       View:      Get Complete INSM Trend Analysis ➞

Stock Chart of BioNTech SE ADRBNTX BioNTech SE ADR
Sector: Health Care
SubSector: Biotechnology
MarketCap: 27035.4 Millions
Recent Price: 98.15    
Market Intelligence Score: 40
Day Percent Change: -1.11828%    
Day Change: -0.53
Week Change: -3.85934%    
Year-to-date Change: -14.9%
BNTX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add BNTX to Watchlist:       View:      Get Complete BNTX Trend Analysis ➞

Stock Chart of AlloVir, Inc.ALVR AlloVir, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 25787 Millions
Recent Price: 11.47    
Market Intelligence Score: 100
Day Percent Change: 16.9215%    
Day Change: -9999
Week Change: 20.8641%    
Year-to-date Change: 10.8%
ALVR Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ALVR to Watchlist:       View:      Get Complete ALVR Trend Analysis ➞

Stock Chart of Cerevel Therapeutics Holdings, Inc.CERE Cerevel Therapeutics Holdings, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 21587 Millions
Recent Price: 44.96    
Market Intelligence Score: 50
Day Percent Change: 0%    
Day Change: -9999
Week Change: 3.66613%    
Year-to-date Change: 0.0%
CERE Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CERE to Watchlist:       View:      Get Complete CERE Trend Analysis ➞

Stock Chart of Petros Pharmaceuticals, Inc.PTPI Petros Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 21487 Millions
Recent Price: 0.03    
Market Intelligence Score: 0
Day Percent Change: -4.7619%    
Day Change: -9999
Week Change: -6.66667%    
Year-to-date Change: -99.8%
PTPI Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PTPI to Watchlist:       View:      Get Complete PTPI Trend Analysis ➞

Stock Chart of Royalty Pharma plcRPRX Royalty Pharma plc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 21036.9 Millions
Recent Price: 35.64    
Market Intelligence Score: 30
Day Percent Change: 0.621118%    
Day Change: 0.2
Week Change: -2.35616%    
Year-to-date Change: 40.0%
RPRX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add RPRX to Watchlist:       View:      Get Complete RPRX Trend Analysis ➞

Stock Chart of Alexion Pharmaceuticals, Inc.ALXN Alexion Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 19427 Millions
Recent Price: 834.36    
Market Intelligence Score: 90
Day Percent Change: 1.90781%    
Day Change: -9999
Week Change: 357.184%    
Year-to-date Change: 0.0%
ALXN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ALXN to Watchlist:       View:      Get Complete ALXN Trend Analysis ➞

Stock Chart of Summit Therapeutics IncSMMT Summit Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 19294.6 Millions
Recent Price: 18.09    
Market Intelligence Score: 30
Day Percent Change: -0.165563%    
Day Change: 0.14
Week Change: -3.90438%    
Year-to-date Change: -1.4%
SMMT Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add SMMT to Watchlist:       View:      Get Complete SMMT Trend Analysis ➞

Stock Chart of Seattle Genetics, Inc.SGEN Seattle Genetics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 18532 Millions
Recent Price: 202.14    
Market Intelligence Score: 30
Day Percent Change: 1.63407%    
Day Change: -9999
Week Change: -8.78159%    
Year-to-date Change: 0.0%
SGEN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add SGEN to Watchlist:       View:      Get Complete SGEN Trend Analysis ➞

Stock Chart of Kronos Bio, Inc.KRON Kronos Bio, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 17287 Millions
Recent Price: 0.88    
Market Intelligence Score: 40
Day Percent Change: 1.48772%    
Day Change: -9999
Week Change: 0.89429%    
Year-to-date Change: -9.3%
KRON Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add KRON to Watchlist:       View:      Get Complete KRON Trend Analysis ➞

Stock Chart of Genmab ADRGMAB Genmab ADR
Sector: Health Care
SubSector: Biotechnology
MarketCap: 16939 Millions
Recent Price: 28.08    
Market Intelligence Score: 90
Day Percent Change: -0.566572%    
Day Change: 0.36
Week Change: 0.898311%    
Year-to-date Change: 33.7%
GMAB Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add GMAB to Watchlist:       View:      Get Complete GMAB Trend Analysis ➞

Stock Chart of Incyte CorpINCY Incyte Corp
Sector: Health Care
SubSector: Biotechnology
MarketCap: 16918.7 Millions
Recent Price: 84.80    
Market Intelligence Score: 80
Day Percent Change: 1.07271%    
Day Change: 1.64
Week Change: -0.934579%    
Year-to-date Change: 22.0%
INCY Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add INCY to Watchlist:       View:      Get Complete INCY Trend Analysis ➞

Stock Chart of Ascendis Pharma A/S ADRASND Ascendis Pharma A/S ADR
Sector: Health Care
SubSector: Biotechnology
MarketCap: 12467.8 Millions
Recent Price: 199.59    
Market Intelligence Score: 90
Day Percent Change: 1.19401%    
Day Change: 0
Week Change: -1.63377%    
Year-to-date Change: 44.6%
ASND Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ASND to Watchlist:       View:      Get Complete ASND Trend Analysis ➞

Stock Chart of Biomarin Pharmaceutical IncBMRN Biomarin Pharmaceutical Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 11092.7 Millions
Recent Price: 54.37    
Market Intelligence Score: 50
Day Percent Change: 0.797182%    
Day Change: 0.57
Week Change: -2.37026%    
Year-to-date Change: -18.2%
BMRN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add BMRN to Watchlist:       View:      Get Complete BMRN Trend Analysis ➞

Stock Chart of BeiGene, Ltd.BGNE BeiGene, Ltd.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 10838.5 Millions
Recent Price: 184.71    
Market Intelligence Score: 40
Day Percent Change: 0.489636%    
Day Change: -9999
Week Change: 4.65156%    
Year-to-date Change: 0.0%
BGNE Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add BGNE to Watchlist:       View:      Get Complete BGNE Trend Analysis ➞

Stock Chart of BridgeBio Pharma IncBBIO BridgeBio Pharma Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 10204.6 Millions
Recent Price: 51.18    
Market Intelligence Score: 60
Day Percent Change: -0.602059%    
Day Change: 1.35
Week Change: -4.33645%    
Year-to-date Change: 81.5%
BBIO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add BBIO to Watchlist:       View:      Get Complete BBIO Trend Analysis ➞

Stock Chart of Exelixis IncEXEL Exelixis Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 10197.4 Millions
Recent Price: 40.44    
Market Intelligence Score: 80
Day Percent Change: 3.32141%    
Day Change: 1.48
Week Change: 5.64263%    
Year-to-date Change: 19.2%
EXEL Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add EXEL to Watchlist:       View:      Get Complete EXEL Trend Analysis ➞

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Click To Change The Sort Order: By Market Cap or Company Size
Performance: Year-to-date, Week and Day
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