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Stock Charts, Performance & Trend Analysis for DNLI
Denali Therapeutics Inc

DNLI
Year-to-Date: -36.6%
This Week: -9.8%
DNLI Stock Charts
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DNLI
Year-to-Date (YTD) Return: -36.6363%
 
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Long Term Trend: Deteriorating
Medium Term Trend: Not Good
Short Term Trend: Very Good
Denali
Overall Trend Score:
40 Out Of 100
Bottomline: Bearish to Neutral Trend


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September 19, 2025 - The year-to-date (YTD) return or performance of Denali (DNLI) is down -36.6363% and is underperforming the overall stock market by -50.4964%.

Recently, the weekly return of Denali (DNLI) is down -9.80191% and is underperforming the overall market by -11.48308%.

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Although long and mid term trends for Denali Therapeutics Inc are not good, the short term trends are improving.

The overall 12Stocks.com Smart Investing & Trading Score is 40 (measures stock trend from 0-bearish to 100-bullish) which puts DNLI in short term bearish to neutral trend.

The Smart Investing & Trading Score from previous trading session is 20 and hence an improvement of trend. Scroll down for key technical charts, support & resistance levels and analysis for Denali.

Stock Analysis for DNLI
Name: Denali Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
In A Glance
Denali (DNLI) Stock Performance and Technical Trend Chart View
 
DNLI Recent Price: 13.21    
MarketCap: 1931.47 Millions
Day Percent Change: 1.11026%
Day Change: 0.72
Week Change: -9.80191%
Year-to-date Change: -36.6363%
Weekly DNLI Technical Chart


Daily DNLI Technical Chart
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Short Term Trend Analysis for DNLI		 
40 / 100
The current technical trend score is 40 in a scale where 0 is bearish and 100 is bullish.
The technical trend score from previous session is 20.
Trend score updated daily. Not to be used for investing.

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DNLI Related Pages
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Compare DNLI's Trend (40) with trends of related stocks
Vertex 10 ➞
Celgene 20 ➞
Poseida 50 ➞
Regeneron 100 ➞
Alnylam 40 ➞
Lilly(Eli) & Co 70 ➞
Johnson & Johnson 30 ➞
Abbvie Inc 100 ➞
Unitedhealth 60 ➞
Astrazeneca 30 ➞
Novartis AG 20 ➞
Abbott 60 ➞
Merck & Co Inc 70 ➞
Thermo Fisher 50 ➞
Novo Nordisk 90 ➞

The table below shows stocks similar to Denali Therapeutics Inc, i.e, from same subsector or sector along with year-to-date (-36.6% YTD), weekly (-9.8%) & daily performaces for comparison. Usually, stocks from similar sector tend to move together but companies that have innovative products, services or good management tend to outperform. Compare 12Stocks.com Smart Investing & Trading Scores to see which stocks in this sector are trending better currently. Click on ticker or stock name for detailed view (place cursor on ticker or stock name to view charts quickly). Click on to add stock symbol to your watchlist and to view watchlist.
Don't forget to get complete 360o overview of best moving sectors
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TickerStock NameWatchlistCategoryRecent PriceSmart Investing & Trading Score
[0 to 100]		Change %Weekly Change%YTD Change%
VRTXVertex  Biotechnology387.1110-0.01-0.4-4.60%
CELGCelgene  Biotechnology55.13201.30-27.70.00%
PSTXPoseida  Biotechnology9.5050-0.630.81.06%
REGNRegeneron  Biotechnology598.711002.267.7-16.06%
ALNYAlnylam  Biotechnology452.17400.10-3.793.55%
INZYInozyme Pharma Biotechnology4.00500.000.340.35%
SPRBSpruce  Biotechnology11.3910012.4939.3-63.79%
ARGXArgen X Biotechnology731.7740-0.35-4.118.00%
INSMInsmed Inc Biotechnology145.86500.75-0.0108.52%
BNTXBioNTech SE Biotechnology96.310-1.87-4.6-16.47%
ALVRAlloVir  Biotechnology11.4710016.9220.910.82%
CERECerevel  Biotechnology44.96500.003.70.00%
PTPIPetros  Biotechnology0.030-4.76-6.7-99.76%
RPRXRoyalty Pharma Biotechnology35.75400.31-1.240.47%
ALXNAlexion  Biotechnology834.36901.91357.20.00%
SMMTSummit  Biotechnology19.23406.309.24.80%
SGENSeattle Genetics Biotechnology202.14301.63-8.80.00%
KRONKronos Bio Biotechnology0.88401.490.9-9.29%
GMABGenmab ADR Biotechnology28.0490-0.141.133.52%
INCYIncyte Corp Biotechnology86.00801.42-0.323.69%
ASNDAscendis Pharma Biotechnology199.3790-0.110.544.47%
BMRNBiomarin  Biotechnology55.14601.421.2-17.07%
BGNEBeiGene  Biotechnology184.71400.494.70.00%
BBIOBridgeBio Pharma Biotechnology53.33904.200.789.11%
EXELExelixis Inc Biotechnology40.45800.027.319.18%
LLYLilly(Eli) & Co Drugs762.93700.371.1-1.58%
JNJJohnson & Johnson Drugs174.1630-1.72-0.922.94%
ABBVAbbvie Inc Drugs221.991000.534.927.12%
UNHUnitedhealth  Insurance334.8260-1.99-3.4-32.88%
AZNAstrazeneca  Drugs77.0730-0.80-4.619.43%
NVSNovartis AG Drugs122.2920-0.15-3.430.42%
ABTAbbott  Instrument134.57600.304.020.34%


Technical Levels: For the trading inclined, the following are the key levels of resistance (ceiling) and support (floor) for DNLI. Ceiling and floor levels are stock prices at which the stock trend gets resistance or support respectively. Stocks & their trends tend to pause at these levels and hence traders have an eye on them.

Long term levels are more important. Stocks that have broken thru their resistance or support levels convincingly tend to have stronger trends (confirm with charts above visually).
Key Technical Levels for DNLI
 Short TermWeeklyLong Term
Resistance (Ceiling)14.8415.0615.38
Support (Floor)14.1512.9113.44

        
RELATIVE PERFORMANCE OF
Denali Therapeutics Inc
Vs
THE MARKET
Relative performance of Denali Therapeutics Inc Compared to Overall Market
How is DNLI faring versus the market [S&P 500] ? Is it lagging or leading ? How is its relative performance ?
Symbol Day Change Week Change Year-to-Date Change
SPY 0.630459% 1.68117% 13.8601%
DNLI 1.11026% -9.80191% -36.6363%

DNLI Chart
S&P 500 (Market) Chart
Year to date returns, DNLI is underperforming the market by -50.4964%
This week, DNLI is underperforming the market by -11.48308%


        
Performance of Denali Therapeutics Inc vs Health Care ETF RELATIVE PERFORMANCE OF
Denali Therapeutics Inc
Vs
Health Care Sector
Let us compare apples to apples and compare performance of DNLI with its sector ETF (contains basket of stocks of same sector) XLV [Health Care SPDR] ?
Symbol Day Change Week Change Year-to-Date Change
XLV 0.196793 % 0.101944 % 0.763773 %
DNLI 1.11026% -9.80191% -36.6363%

DNLI Chart
Health Care Chart
Year to date, DNLI is underperforming Health Care sector by -37.400073%
This week, DNLI is underperforming Health Care sector by -9.903854%

List Of ETF Funds Related To Denali Therapeutics Inc

The table below shows ETFs (Exchange Traded Funds) similar to Denali Therapeutics Inc, i.e, from same sector along with year-to-date (YTD), weekly & daily performaces for comparison. Usually, ETFs and associated stocks from similar sector tend to move together but companies that have innovative products, services or good management tend to outperform. Move mouse or cursor over ETF symbol to view short-term technical chart and over ETF name to view long term chart. Click on to add ETF symbol to your watchlist and to view watchlist.
TickerStock NameWatchlistCategoryRecent PriceChange %Weekly Change%YTD Change%
BBHBiotech HOLDRs Health Care167.530.956371.298226.67792%
IBBiShares Nasdaq Biotechnology Health Care143.631.865252.118738.16164%
RXLProShares Ultra HealthCare  Health Care41.430.516835-0.110197-5.07557%
PPHPharmaceutical HOLDRs Health Care88.870.327388-0.3028944.24609%
RXDProShares UltraShort HealthCare  Health Care11.78-0.4260210.0977185-1.0084%
XLVHealth Care SPDR Health Care137.470.1967930.1019440.763773%
IXJiShares Global Healthcare  Health Care87.850.25105603.03462%
IHFiShares U. S. Healthcare Providers Health Care48.140.4171880.06235710.962648%
XBISPDR Biotech Health Care96.683.103342.96065.64227%
PBEPowerShares Biotech  Health Care71.032.094441.538846.1196%
FBTFT Biotech Index Fund Health Care180.072.053843.264698.0228%
IYHiShares US Healthcare Health Care57.910.277056-0.0517777-0.179611%
VHTVanguard Health Care VIPERS Health Care256.580.517120.3873391.74035%
PJPPowerShares Pharmaceuticals Health Care92.741.45443-0.1491212.4686%
IHIiShares U.S. Medical Devices Health Care60.590.39768-0.5090314.04378%
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