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Best Biotech Stocks

Quick Read: Best Biotech Stocks List By Performances & Trends:
Daily, Weekly, Year-to-Date, Market Cap (Size) & Technical Trends
Best Biotech Stocks Views: Quick Browse View, Summary & Slide Show View

12Stocks.com Biotech Stocks Performances & Trends Daily
October 3, 2025 - All trends (long term, mid-term and short term) for Biotech sector looks good.

The overall market intelligence score is 100 (0-bearish to 100-bullish) which puts Biotech sector in short term bullish trend.

The market intelligence score from previous trading session is 90 and an improvement of trend continues.

 Year To Date Performance: 12.1001 %
 Weekly Performance: 5.2853 %
 Daily Performance: 1.18355 %
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Biotech Sector Trend
100 / 100
Here are the market intelligence trend scores of the most requested Biotech stocks at 12Stocks.com (click stock name for detailed review):

12Stocks.com: Investing in Biotech sector with Stocks
The following table helps investors and traders sort through current performance and trends (as measured by market intelligence score) of various stocks in the Biotech sector.

Quick View: Move mouse or cursor over stock symbol (ticker) to view short-term Technical chart and over stock name to view long term chart. Click on to add stock symbol to your watchlist and to view watchlist. Click on any ticker or stock name for detailed market intelligence report for that stock.

12Stocks.com Performance of Stocks in Biotech Sector

TickerStock NameWatchlistCategoryRecent PriceMarket Intelligence ScoreChange %YTD Change%
INSMInsmed  Biotechnology152.83903.77118.49%
SGMOSangamo  Biotechnology0.70803.77-38.05%
XERSXeris Biopharma Biotechnology8.31903.75140.17%
SRRASierra Oncology Biotechnology14.95303.680.00%
AIMTAimmune  Biotechnology150.75703.660.00%
TECHBio-Techne Corp Biotechnology62.091003.62-12.89%
SPROSpero  Biotechnology2.03603.5787.96%
VTYXVentyx  Biotechnology3.53543.5221.00%
GNFTGenfit ADR Biotechnology3.98603.514.05%
BMEABiomea Fusion Biotechnology2.09803.47-43.36%
PLRXPliant  Biotechnology1.50503.45-88.70%
HOOKHOOKIPA Pharma Biotechnology0.92703.37-52.82%
CMPXCompass  Biotechnology3.47303.27147.86%
PDLIPDL BioPharma Biotechnology22.03903.230.00%
HRTXHeron  Biotechnology1.29603.20-19.38%
INBXInhibrx  Biotechnology35.061003.19129.93%
MCRBSeres  Biotechnology21.151003.1725.40%
ARGXArgen X Biotechnology791.591003.1627.64%
ARNAArena  Biotechnology2.34203.080.00%
RAREUltragenyx  Biotechnology30.911003.07-24.88%
ANNXAnnexon  Biotechnology3.12802.97-43.27%
SLNSilence  Biotechnology5.25302.94-26.98%
ACHVAchieve Life Biotechnology3.191002.90-13.55%
TRILTrillium  Biotechnology56.00802.880.00%
NKTRNektar  Biotechnology60.52902.84319.84%
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Performance: Year-to-date, Week and Day
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Detailed Overview of Biotech Stocks
Biotech Technical Overview, Leaders & Laggards, Top Biotech ETF Funds & Detailed Biotech Stocks List, Charts, Trends & More

Biotech Sector: Technical Analysis, Trends & YTD Performance
Biotech sector, as represented by XBI, an exchange-traded fund [ETF] that holds basket of Biotech stocks (e.g, Amgen, Celgene) is up by 12.1001% and is currently underperforming the overall market by -2.6578% year-to-date. Below is a quick view of Technical charts and trends:

XBI Weekly Chart
Long Term Trend: Very Good
Medium Term Trend: Very Good

XBI Daily Chart
Short Term Trend: Very Good
Overall Trend Score: 100
YTD Performance: 12.1001%
**Trend Scores & Views Are Only For Educational Purposes And Not For Investing


12Stocks.com: Top Performing Biotech Sector Stocks
Hot Biotech Stocks of 2025 We try to spot trends by analyzing the performances of various stocks or components within Biotech sector and try to find best performing stocks. The movers and shakers. The winners and losers.

The top performing Biotech sector stocks year to date are
Vor Biopharma[3175%] Nanobiotix ADR[581%] I-Mab ADR[358%]
Monopar [337%] Nektar [320%] DBV Technologies[277%]
Celcuity [276%] Galectin [263%] Cidara [261%]
Lineage Cell[234%] ATAI Life[221%]
View complete list of Biotech stocks by year-to-date performance

Now, more recently, over last week, the top performing Biotech sector stocks on the move are
Athersys [193287%] VBI Vaccines[86898.5%] ContraFect [47677.8%]
Clovis Oncology[39610.5%] NanoString Technologies[17224.7%] Neptune Wellness[14100%]
Achillion [10033.3%] Nymox [8258.5%] Epizyme [5739.5%]
Portola [4717.6%] Strongbridge Biopharma[3417.5%]
View complete list of Biotech stocks by weekly performance

Unfortunately not all Biotech stocks have done well this year. Investors of these stocks hope they have seen the worst and hope that these stocks are set to bounce back. The bearish stocks in this index year to date (YTD) are
Vaxxinity [-100%] Petros [-100%] Translate Bio[-95%]
Palatin Technologies[-93%] Syros [-91%] Pliant [-89%]
Affimed N.V[-87%] MoonLake Immuno[-86%] Unity nology[-86%]
Sarepta [-82%] Kala Bio[-80%] IGM [-80%]
.
Investors can get enhanced performance by riding the current stock trends. Using complex algorithms, 12Stocks.com has come up with market intelligence scores (on 0-bearish to 100-bullish scale) to identify best trending stocks. Top trending Biotech stocks are
Taysha Gene[100] DBV Technologies[100] Valneva SE[100]
Prime Medicine[100] AlloVir [100] Sarepta [100]
Monopar [100] Cara [100] Absci Corp[100]
Spruce [100] Cabaletta Bio[100] Compugen [100]
View complete list of Biotech stocks by 12Stocks.com trends

12Stocks.com: Investing in Biotech Sector using Exchange Traded Funds
The following table shows list of key exchange traded funds (ETF) that help investors track Biotech Index. For detailed view, check out our ETF Funds section of our website.

Quick View: Move mouse or cursor over ETF symbol (ticker) to view short-term Technical chart and over ETF name to view long term chart. Click on ticker or stock name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist.

12Stocks.com List of ETFs that track Biotech Index

TickerETF NameWatchlistRecent PriceMarket Intelligence ScoreChange %Week %Year-to-date %
UBIOBiotechnology  73.3480-0.0681292260.7480%
HCRFEdge Multifactor 67.142309999NA
SICKHealthcare Bear 3X 37.903609999NA
LABSBiotech Bear 1X 24.185609999NA
BTECPrincipal Healthcare Innovators 39.493001.023280%
 Market Intelligence Score (0-Bearish to 100-Bullish)
12Stocks.com: Charts, Trends, Fundamental Data and Performances of Biotech Stocks
We now take in-depth look at all Biotech stocks including charts, multi-period performances and overall trends (as measured by market intelligence score).

One can sort Biotech stocks (click link to choose) by Daily, Weekly and by Year-to-Date performances. Also, one can sort by size of the company or by market capitalization.
Select Your Default Chart Type:
Long Term Chart Daily Chart Weekly Chart 
Long Term Chart (Default)
Weekly Chart Example
Daily Chart Example
Click on stock symbol or name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist. Quick View: Move mouse or cursor over "Daily" to quickly view daily Technical stock chart and over "Weekly" to view weekly Technical stock chart.

Stock Chart of Insmed IncINSM Insmed Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 30670.5 Millions
Recent Price: 152.83    
Market Intelligence Score: 90
Day Percent Change: 3.76833%    
Day Change: 3.15
Week Change: 8.39007%    
Year-to-date Change: 118.5%
INSM Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add INSM to Watchlist:       View:      Get Complete INSM Trend Analysis ➞

Stock Chart of Sangamo Therapeutics IncSGMO Sangamo Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 165.1 Millions
Recent Price: 0.70    
Market Intelligence Score: 80
Day Percent Change: 3.76519%    
Day Change: 0.03
Week Change: 23.9157%    
Year-to-date Change: -38.1%
SGMO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add SGMO to Watchlist:       View:      Get Complete SGMO Trend Analysis ➞

Stock Chart of Xeris Biopharma Holdings IncXERS Xeris Biopharma Holdings Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1267.62 Millions
Recent Price: 8.31    
Market Intelligence Score: 90
Day Percent Change: 3.74532%    
Day Change: 0.02
Week Change: 3.875%    
Year-to-date Change: 140.2%
XERS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add XERS to Watchlist:       View:      Get Complete XERS Trend Analysis ➞

Stock Chart of Sierra Oncology, Inc.SRRA Sierra Oncology, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 125.185 Millions
Recent Price: 14.95    
Market Intelligence Score: 30
Day Percent Change: 3.67545%    
Day Change: -9999
Week Change: -72.8132%    
Year-to-date Change: 0.0%
SRRA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add SRRA to Watchlist:       View:      Get Complete SRRA Trend Analysis ➞

Stock Chart of Aimmune Therapeutics, Inc.AIMT Aimmune Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 903.485 Millions
Recent Price: 150.75    
Market Intelligence Score: 70
Day Percent Change: 3.65812%    
Day Change: -9999
Week Change: -12.7352%    
Year-to-date Change: 0.0%
AIMT Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add AIMT to Watchlist:       View:      Get Complete AIMT Trend Analysis ➞

Stock Chart of Bio-Techne CorpTECH Bio-Techne Corp
Sector: Health Care
SubSector: Biotechnology
MarketCap: 8463.45 Millions
Recent Price: 62.09    
Market Intelligence Score: 100
Day Percent Change: 3.6215%    
Day Change: 2.48
Week Change: 21.2222%    
Year-to-date Change: -12.9%
TECH Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add TECH to Watchlist:       View:      Get Complete TECH Trend Analysis ➞

Stock Chart of Spero Therapeutics IncSPRO Spero Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 120.99 Millions
Recent Price: 2.03    
Market Intelligence Score: 60
Day Percent Change: 3.57143%    
Day Change: 0.03
Week Change: 3.04569%    
Year-to-date Change: 88.0%
SPRO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add SPRO to Watchlist:       View:      Get Complete SPRO Trend Analysis ➞

Stock Chart of Ventyx Biosciences IncVTYX Ventyx Biosciences Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 179.7 Millions
Recent Price: 3.53    
Market Intelligence Score: 54
Day Percent Change: 3.52%    
Day Change: 0.09
Week Change: -11.67%    
Year-to-date Change: 21.0%
VTYX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add VTYX to Watchlist:       View:      Get Complete VTYX Trend Analysis ➞

Stock Chart of Genfit ADRGNFT Genfit ADR
Sector: Health Care
SubSector: Biotechnology
MarketCap: 196.21 Millions
Recent Price: 3.98    
Market Intelligence Score: 60
Day Percent Change: 3.50649%    
Day Change: -0.2
Week Change: -9.07017%    
Year-to-date Change: 4.0%
GNFT Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add GNFT to Watchlist:       View:      Get Complete GNFT Trend Analysis ➞

Stock Chart of Biomea Fusion IncBMEA Biomea Fusion Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 114.26 Millions
Recent Price: 2.09    
Market Intelligence Score: 80
Day Percent Change: 3.46535%    
Day Change: 0.01
Week Change: 5.02513%    
Year-to-date Change: -43.4%
BMEA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add BMEA to Watchlist:       View:      Get Complete BMEA Trend Analysis ➞

Stock Chart of Pliant Therapeutics IncPLRX Pliant Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 114.18 Millions
Recent Price: 1.50    
Market Intelligence Score: 50
Day Percent Change: 3.44828%    
Day Change: 0.02
Week Change: 2.73973%    
Year-to-date Change: -88.7%
PLRX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PLRX to Watchlist:       View:      Get Complete PLRX Trend Analysis ➞

Stock Chart of HOOKIPA Pharma Inc.HOOK HOOKIPA Pharma Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 294.785 Millions
Recent Price: 0.92    
Market Intelligence Score: 70
Day Percent Change: 3.37079%    
Day Change: 0
Week Change: 0.987925%    
Year-to-date Change: -52.8%
HOOK Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add HOOK to Watchlist:       View:      Get Complete HOOK Trend Analysis ➞

Stock Chart of Compass Therapeutics IncCMPX Compass Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 590.21 Millions
Recent Price: 3.47    
Market Intelligence Score: 30
Day Percent Change: 3.27381%    
Day Change: 0.02
Week Change: -0.573066%    
Year-to-date Change: 147.9%
CMPX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CMPX to Watchlist:       View:      Get Complete CMPX Trend Analysis ➞

Stock Chart of PDL BioPharma, Inc.PDLI PDL BioPharma, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 310.085 Millions
Recent Price: 22.03    
Market Intelligence Score: 90
Day Percent Change: 3.23336%    
Day Change: -9999
Week Change: 112.645%    
Year-to-date Change: 0.0%
PDLI Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PDLI to Watchlist:       View:      Get Complete PDLI Trend Analysis ➞

Stock Chart of Heron Therapeutics IncHRTX Heron Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 200.81 Millions
Recent Price: 1.29    
Market Intelligence Score: 60
Day Percent Change: 3.2%    
Day Change: 0.02
Week Change: 3.2%    
Year-to-date Change: -19.4%
HRTX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add HRTX to Watchlist:       View:      Get Complete HRTX Trend Analysis ➞

Stock Chart of Inhibrx Biosciences IncINBX Inhibrx Biosciences Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 408.2 Millions
Recent Price: 35.06    
Market Intelligence Score: 100
Day Percent Change: 3.19305%    
Day Change: -0.25
Week Change: 18.064%    
Year-to-date Change: 129.9%
INBX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add INBX to Watchlist:       View:      Get Complete INBX Trend Analysis ➞

Stock Chart of Seres Therapeutics IncMCRB Seres Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 169.49 Millions
Recent Price: 21.15    
Market Intelligence Score: 100
Day Percent Change: 3.17073%    
Day Change: 0.38
Week Change: 9.07684%    
Year-to-date Change: 25.4%
MCRB Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add MCRB to Watchlist:       View:      Get Complete MCRB Trend Analysis ➞

Stock Chart of Argen X SE ADRARGX Argen X SE ADR
Sector: Health Care
SubSector: Biotechnology
MarketCap: 45947.7 Millions
Recent Price: 791.59    
Market Intelligence Score: 100
Day Percent Change: 3.16161%    
Day Change: 14.32
Week Change: 8.47265%    
Year-to-date Change: 27.6%
ARGX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ARGX to Watchlist:       View:      Get Complete ARGX Trend Analysis ➞

Stock Chart of Arena Pharmaceuticals, Inc.ARNA Arena Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1936.25 Millions
Recent Price: 2.34    
Market Intelligence Score: 20
Day Percent Change: 3.0837%    
Day Change: -9999
Week Change: -97.6598%    
Year-to-date Change: 0.0%
ARNA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ARNA to Watchlist:       View:      Get Complete ARNA Trend Analysis ➞

Stock Chart of Ultragenyx Pharmaceutical IncRARE Ultragenyx Pharmaceutical Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 3066.55 Millions
Recent Price: 30.91    
Market Intelligence Score: 100
Day Percent Change: 3.06769%    
Day Change: 0.75
Week Change: 7.47566%    
Year-to-date Change: -24.9%
RARE Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add RARE to Watchlist:       View:      Get Complete RARE Trend Analysis ➞

Stock Chart of Annexon IncANNX Annexon Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 238.45 Millions
Recent Price: 3.12    
Market Intelligence Score: 80
Day Percent Change: 2.9703%    
Day Change: 0.03
Week Change: 10.6383%    
Year-to-date Change: -43.3%
ANNX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ANNX to Watchlist:       View:      Get Complete ANNX Trend Analysis ➞

Stock Chart of Silence Therapeutics Plc ADRSLN Silence Therapeutics Plc ADR
Sector: Health Care
SubSector: Biotechnology
MarketCap: 268.74 Millions
Recent Price: 5.25    
Market Intelligence Score: 30
Day Percent Change: 2.94118%    
Day Change: 0.13
Week Change: 2.14008%    
Year-to-date Change: -27.0%
SLN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add SLN to Watchlist:       View:      Get Complete SLN Trend Analysis ➞

Stock Chart of Achieve Life Sciences IncACHV Achieve Life Sciences Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 144.63 Millions
Recent Price: 3.19    
Market Intelligence Score: 100
Day Percent Change: 2.90323%    
Day Change: 0.31
Week Change: 3.57143%    
Year-to-date Change: -13.6%
ACHV Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ACHV to Watchlist:       View:      Get Complete ACHV Trend Analysis ➞

Stock Chart of Trillium Therapeutics Inc.TRIL Trillium Therapeutics Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 250.885 Millions
Recent Price: 56.00    
Market Intelligence Score: 80
Day Percent Change: 2.88444%    
Day Change: -9999
Week Change: 203.688%    
Year-to-date Change: 0.0%
TRIL Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add TRIL to Watchlist:       View:      Get Complete TRIL Trend Analysis ➞

Stock Chart of Nektar TherapeuticsNKTR Nektar Therapeutics
Sector: Health Care
SubSector: Biotechnology
MarketCap: 764.17 Millions
Recent Price: 60.52    
Market Intelligence Score: 90
Day Percent Change: 2.83772%    
Day Change: 1.05
Week Change: 0.314935%    
Year-to-date Change: 319.8%
NKTR Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add NKTR to Watchlist:       View:      Get Complete NKTR Trend Analysis ➞

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Performance: Year-to-date, Week and Day
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