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Best Biotech Stocks

Quick Read: Best Biotech Stocks List By Performances & Trends:
Daily, Weekly, Year-to-Date, Market Cap (Size) & Technical Trends
Best Biotech Stocks Views: Quick Browse View, Summary & Slide Show View

12Stocks.com Biotech Stocks Performances & Trends Daily
September 18, 2025 - All trends (long term, mid-term and short term) for Biotech sector looks good.

The overall market intelligence score is 100 (0-bearish to 100-bullish) which puts Biotech sector in short term bullish trend.

The market intelligence score from previous trading session is 80 and hence an improvement of trend.

 Year To Date Performance: 5.15055 %
 Weekly Performance: 2.48136 %
 Daily Performance: 2.62344 %
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Biotech Sector Trend
100 / 100
Here are the market intelligence trend scores of the most requested Biotech stocks at 12Stocks.com (click stock name for detailed review):

12Stocks.com: Investing in Biotech sector with Stocks
The following table helps investors and traders sort through current performance and trends (as measured by market intelligence score) of various stocks in the Biotech sector.

Quick View: Move mouse or cursor over stock symbol (ticker) to view short-term Technical chart and over stock name to view long term chart. Click on to add stock symbol to your watchlist and to view watchlist. Click on any ticker or stock name for detailed market intelligence report for that stock.

12Stocks.com Performance of Stocks in Biotech Sector

TickerStock NameWatchlistCategoryRecent PriceMarket Intelligence ScoreChange %YTD Change%
INOInovio  Biotechnology2.1830-4.3919.78%
CYTKCytokinetics  Biotechnology47.5640-4.42-2.80%
CRBUCaribou  Biotechnology1.7220-4.442.38%
PLRXPliant  Biotechnology1.4630-4.58-89.01%
KALAKala Bio Biotechnology17.4770-4.64126.59%
PTPIPetros  Biotechnology0.030-4.76-99.76%
ANNXAnnexon  Biotechnology2.5280-4.91-54.18%
CRTXCortexyme  Biotechnology1.3330-5.000.00%
BFRABiofrontera AG Biotechnology1.9410-5.370.00%
ABSIAbsci Corp Biotechnology2.5530-5.56-5.90%
CDXSCodexis  Biotechnology2.350-5.62-53.00%
MLYSMineralys  Biotechnology37.2910-5.6218.68%
CGEMCullinan  Biotechnology5.9310-5.72-52.14%
EQEquillium  Biotechnology1.5330-6.1399.01%
GOSSGossamer Bio Biotechnology2.9950-6.56208.25%
MOLNMolecular Partners Biotechnology3.6320-6.68-25.46%
RCKTRocket  Biotechnology3.0330-6.77-76.18%
LYELLyell Immunopharma Biotechnology12.3150-6.88-4.57%
PFNXPfenex  Biotechnology10.2110-6.930.00%
CBMGCellular Biomedicine Biotechnology10.2120-6.930.00%
VCELVericel Corp Biotechnology30.020-9.66-45.53%
EVFMEvofem  Biotechnology0.0130-10.00-6.25%
UBXUnity nology Biotechnology0.160-20.04-85.96%
PIRSPieris  Biotechnology12.030-27.160.00%
AFMDAffimed N.V Biotechnology0.1820-34.95-86.56%
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Performance: Year-to-date, Week and Day
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Detailed Overview of Biotech Stocks
Biotech Technical Overview, Leaders & Laggards, Top Biotech ETF Funds & Detailed Biotech Stocks List, Charts, Trends & More

Biotech Sector: Technical Analysis, Trends & YTD Performance
Biotech sector, as represented by XBI, an exchange-traded fund [ETF] that holds basket of Biotech stocks (e.g, Amgen, Celgene) is up by 5.15055% and is currently underperforming the overall market by -8.86965% year-to-date. Below is a quick view of Technical charts and trends:

XBI Weekly Chart
Long Term Trend: Very Good
Medium Term Trend: Very Good

XBI Daily Chart
Short Term Trend: Very Good
Overall Trend Score: 100
YTD Performance: 5.15055%
**Trend Scores & Views Are Only For Educational Purposes And Not For Investing


12Stocks.com: Top Performing Biotech Sector Stocks
Hot Biotech Stocks of 2025 We try to spot trends by analyzing the performances of various stocks or components within Biotech sector and try to find best performing stocks. The movers and shakers. The winners and losers.

The top performing Biotech sector stocks year to date are
Celcuity [316%] I-Mab ADR[307%] Galectin [292%]
Immuneering Corp[265%] Nektar [254%] Precigen [254%]
Nanobiotix ADR[252%] Gossamer Bio[208%] DBV Technologies[203%]
Monopar [200%] ATAI Life[194%]
View complete list of Biotech stocks by year-to-date performance

Now, more recently, over last week, the top performing Biotech sector stocks on the move are
Athersys [193287%] VBI Vaccines[86898.5%] ContraFect [47677.8%]
Clovis Oncology[39610.5%] NanoString Technologies[17224.7%] Neptune Wellness[14100%]
Achillion [10033.3%] Nymox [8258.5%] Epizyme [5739.5%]
Portola [4717.6%] Strongbridge Biopharma[3417.5%]
View complete list of Biotech stocks by weekly performance

Unfortunately not all Biotech stocks have done well this year. Investors of these stocks hope they have seen the worst and hope that these stocks are set to bounce back. The bearish stocks in this index year to date (YTD) are
Vaxxinity [-100%] Petros [-100%] Translate Bio[-95%]
Palatin Technologies[-93%] Syros [-91%] Pliant [-89%]
Affimed N.V[-87%] Unity nology[-86%] Sarepta [-84%]
IGM [-80%] Rocket [-76%] Allakos [-73%]
.
Investors can get enhanced performance by riding the current stock trends. Using complex algorithms, 12Stocks.com has come up with market intelligence scores (on 0-bearish to 100-bullish scale) to identify best trending stocks. Top trending Biotech stocks are
AlloVir [100] Monopar [100] Cara [100]
Corbus [100] Ocugen [100] Spruce [100]
Roivant [100] Xencor [100] Oncolytics [100]
Tango [100] Arcus [100] RAPT [100]
View complete list of Biotech stocks by 12Stocks.com trends

12Stocks.com: Investing in Biotech Sector using Exchange Traded Funds
The following table shows list of key exchange traded funds (ETF) that help investors track Biotech Index. For detailed view, check out our ETF Funds section of our website.

Quick View: Move mouse or cursor over ETF symbol (ticker) to view short-term Technical chart and over ETF name to view long term chart. Click on ticker or stock name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist.

12Stocks.com List of ETFs that track Biotech Index

TickerETF NameWatchlistRecent PriceMarket Intelligence ScoreChange %Week %Year-to-date %
UBIOBiotechnology  73.3480-0.0681292260.7480%
HCRFEdge Multifactor 67.142309999NA
SICKHealthcare Bear 3X 37.903609999NA
LABSBiotech Bear 1X 24.185609999NA
BTECPrincipal Healthcare Innovators 39.493001.023280%
 Market Intelligence Score (0-Bearish to 100-Bullish)
12Stocks.com: Charts, Trends, Fundamental Data and Performances of Biotech Stocks
We now take in-depth look at all Biotech stocks including charts, multi-period performances and overall trends (as measured by market intelligence score).

One can sort Biotech stocks (click link to choose) by Daily, Weekly and by Year-to-Date performances. Also, one can sort by size of the company or by market capitalization.
Select Your Default Chart Type:
Long Term Chart Daily Chart Weekly Chart 
Long Term Chart (Default)
Weekly Chart Example
Daily Chart Example
Click on stock symbol or name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist. Quick View: Move mouse or cursor over "Daily" to quickly view daily Technical stock chart and over "Weekly" to view weekly Technical stock chart.

Stock Chart of Inovio Pharmaceuticals IncINO Inovio Pharmaceuticals Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 148.27 Millions
Recent Price: 2.18    
Market Intelligence Score: 30
Day Percent Change: -4.38596%    
Day Change: 0.06
Week Change: -20.7273%    
Year-to-date Change: 19.8%
INO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add INO to Watchlist:       View:      Get Complete INO Trend Analysis ➞

Stock Chart of Cytokinetics IncCYTK Cytokinetics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 6343.03 Millions
Recent Price: 47.56    
Market Intelligence Score: 40
Day Percent Change: -4.42122%    
Day Change: 0.73
Week Change: -7.65049%    
Year-to-date Change: -2.8%
CYTK Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CYTK to Watchlist:       View:      Get Complete CYTK Trend Analysis ➞

Stock Chart of Caribou Biosciences IncCRBU Caribou Biosciences Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 174.14 Millions
Recent Price: 1.72    
Market Intelligence Score: 20
Day Percent Change: -4.44444%    
Day Change: 0.04
Week Change: -6.52174%    
Year-to-date Change: 2.4%
CRBU Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CRBU to Watchlist:       View:      Get Complete CRBU Trend Analysis ➞

Stock Chart of Pliant Therapeutics IncPLRX Pliant Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 114.18 Millions
Recent Price: 1.46    
Market Intelligence Score: 30
Day Percent Change: -4.57516%    
Day Change: 0.02
Week Change: -16.5714%    
Year-to-date Change: -89.0%
PLRX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PLRX to Watchlist:       View:      Get Complete PLRX Trend Analysis ➞

Stock Chart of Kala Bio IncKALA Kala Bio Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 102.16 Millions
Recent Price: 17.47    
Market Intelligence Score: 70
Day Percent Change: -4.63974%    
Day Change: 0.16
Week Change: 20.234%    
Year-to-date Change: 126.6%
KALA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add KALA to Watchlist:       View:      Get Complete KALA Trend Analysis ➞

Stock Chart of Petros Pharmaceuticals, Inc.PTPI Petros Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 21487 Millions
Recent Price: 0.03    
Market Intelligence Score: 0
Day Percent Change: -4.7619%    
Day Change: -9999
Week Change: -6.66667%    
Year-to-date Change: -99.8%
PTPI Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PTPI to Watchlist:       View:      Get Complete PTPI Trend Analysis ➞

Stock Chart of Annexon IncANNX Annexon Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 238.45 Millions
Recent Price: 2.52    
Market Intelligence Score: 80
Day Percent Change: -4.90566%    
Day Change: 0.03
Week Change: 18.8679%    
Year-to-date Change: -54.2%
ANNX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ANNX to Watchlist:       View:      Get Complete ANNX Trend Analysis ➞

Stock Chart of Cortexyme, Inc.CRTX Cortexyme, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1406.45 Millions
Recent Price: 1.33    
Market Intelligence Score: 30
Day Percent Change: -5%    
Day Change: -9999
Week Change: -1.48148%    
Year-to-date Change: 0.0%
CRTX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CRTX to Watchlist:       View:      Get Complete CRTX Trend Analysis ➞

Stock Chart of Biofrontera AGBFRA Biofrontera AG
Sector: Health Care
SubSector: Biotechnology
MarketCap: 166.685 Millions
Recent Price: 1.94    
Market Intelligence Score: 10
Day Percent Change: -5.36585%    
Day Change: -9999
Week Change: -12.809%    
Year-to-date Change: 0.0%
BFRA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add BFRA to Watchlist:       View:      Get Complete BFRA Trend Analysis ➞

Stock Chart of Absci CorpABSI Absci Corp
Sector: Health Care
SubSector: Biotechnology
MarketCap: 367.83 Millions
Recent Price: 2.55    
Market Intelligence Score: 30
Day Percent Change: -5.55556%    
Day Change: -0.01
Week Change: 0.393701%    
Year-to-date Change: -5.9%
ABSI Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ABSI to Watchlist:       View:      Get Complete ABSI Trend Analysis ➞

Stock Chart of Codexis IncCDXS Codexis Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 218.45 Millions
Recent Price: 2.35    
Market Intelligence Score: 0
Day Percent Change: -5.62249%    
Day Change: 0
Week Change: -4.08163%    
Year-to-date Change: -53.0%
CDXS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CDXS to Watchlist:       View:      Get Complete CDXS Trend Analysis ➞

Stock Chart of Mineralys Therapeutics IncMLYS Mineralys Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 2648.25 Millions
Recent Price: 37.29    
Market Intelligence Score: 10
Day Percent Change: -5.62%    
Day Change: -0.87
Week Change: 3.4%    
Year-to-date Change: 18.7%
MLYS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add MLYS to Watchlist:       View:      Get Complete MLYS Trend Analysis ➞

Stock Chart of Cullinan Therapeutics IncCGEM Cullinan Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 412.93 Millions
Recent Price: 5.93    
Market Intelligence Score: 10
Day Percent Change: -5.72337%    
Day Change: 0.2
Week Change: -13.1772%    
Year-to-date Change: -52.1%
CGEM Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CGEM to Watchlist:       View:      Get Complete CGEM Trend Analysis ➞

Stock Chart of Equillium IncEQ Equillium Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 113.65 Millions
Recent Price: 1.53    
Market Intelligence Score: 30
Day Percent Change: -6.13497%    
Day Change: 0.42
Week Change: -16.3934%    
Year-to-date Change: 99.0%
EQ Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add EQ to Watchlist:       View:      Get Complete EQ Trend Analysis ➞

Stock Chart of Gossamer Bio IncGOSS Gossamer Bio Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 668.5 Millions
Recent Price: 2.99    
Market Intelligence Score: 50
Day Percent Change: -6.5625%    
Day Change: 0.22
Week Change: 7.94224%    
Year-to-date Change: 208.2%
GOSS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add GOSS to Watchlist:       View:      Get Complete GOSS Trend Analysis ➞

Stock Chart of Molecular Partners AG ADRMOLN Molecular Partners AG ADR
Sector: Health Care
SubSector: Biotechnology
MarketCap: 133.86 Millions
Recent Price: 3.63    
Market Intelligence Score: 20
Day Percent Change: -6.6838%    
Day Change: 0.01
Week Change: 4.61095%    
Year-to-date Change: -25.5%
MOLN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add MOLN to Watchlist:       View:      Get Complete MOLN Trend Analysis ➞

Stock Chart of Rocket Pharmaceuticals IncRCKT Rocket Pharmaceuticals Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 353.92 Millions
Recent Price: 3.03    
Market Intelligence Score: 30
Day Percent Change: -6.76923%    
Day Change: -0.02
Week Change: -5.60748%    
Year-to-date Change: -76.2%
RCKT Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add RCKT to Watchlist:       View:      Get Complete RCKT Trend Analysis ➞

Stock Chart of Lyell Immunopharma IncLYEL Lyell Immunopharma Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 233.42 Millions
Recent Price: 12.31    
Market Intelligence Score: 50
Day Percent Change: -6.88351%    
Day Change: 0
Week Change: -6.38783%    
Year-to-date Change: -4.6%
LYEL Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add LYEL to Watchlist:       View:      Get Complete LYEL Trend Analysis ➞

Stock Chart of Pfenex Inc.PFNX Pfenex Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 260.685 Millions
Recent Price: 10.21    
Market Intelligence Score: 10
Day Percent Change: -6.92799%    
Day Change: -9999
Week Change: -85.8017%    
Year-to-date Change: 0.0%
PFNX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PFNX to Watchlist:       View:      Get Complete PFNX Trend Analysis ➞

Stock Chart of Cellular Biomedicine Group, Inc.CBMG Cellular Biomedicine Group, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 329.885 Millions
Recent Price: 10.21    
Market Intelligence Score: 20
Day Percent Change: -6.92799%    
Day Change: -9999
Week Change: -25.5831%    
Year-to-date Change: 0.0%
CBMG Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CBMG to Watchlist:       View:      Get Complete CBMG Trend Analysis ➞

Stock Chart of Vericel CorpVCEL Vericel Corp
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1718.17 Millions
Recent Price: 30.02    
Market Intelligence Score: 0
Day Percent Change: -9.65995%    
Day Change: 0.08
Week Change: -7.74431%    
Year-to-date Change: -45.5%
VCEL Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add VCEL to Watchlist:       View:      Get Complete VCEL Trend Analysis ➞

Stock Chart of Evofem Biosciences, Inc.EVFM Evofem Biosciences, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 243.385 Millions
Recent Price: 0.01    
Market Intelligence Score: 30
Day Percent Change: -10%    
Day Change: -9999
Week Change: 0%    
Year-to-date Change: -6.3%
EVFM Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add EVFM to Watchlist:       View:      Get Complete EVFM Trend Analysis ➞

Stock Chart of Unity Biotechnology, Inc.UBX Unity Biotechnology, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 254.985 Millions
Recent Price: 0.16    
Market Intelligence Score: 0
Day Percent Change: -20.04%    
Day Change: -9999
Week Change: -58.3333%    
Year-to-date Change: -86.0%
UBX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add UBX to Watchlist:       View:      Get Complete UBX Trend Analysis ➞

Stock Chart of Pieris Pharmaceuticals, Inc.PIRS Pieris Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 150.785 Millions
Recent Price: 12.03    
Market Intelligence Score: 0
Day Percent Change: -27.1565%    
Day Change: -9999
Week Change: -26.4694%    
Year-to-date Change: 0.0%
PIRS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PIRS to Watchlist:       View:      Get Complete PIRS Trend Analysis ➞

Stock Chart of Affimed N.V.AFMD Affimed N.V.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 161.385 Millions
Recent Price: 0.18    
Market Intelligence Score: 20
Day Percent Change: -34.9462%    
Day Change: -9999
Week Change: -73.5036%    
Year-to-date Change: -86.6%
AFMD Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add AFMD to Watchlist:       View:      Get Complete AFMD Trend Analysis ➞

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Click To Change The Sort Order: By Market Cap or Company Size
Performance: Year-to-date, Week and Day
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