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Best Biotech Stocks

Quick Read: Best Biotech Stocks List By Performances & Trends:
Daily, Weekly, Year-to-Date, Market Cap (Size) & Technical Trends
Best Biotech Stocks Views: Quick Browse View, Summary & Slide Show View

12Stocks.com Biotech Stocks Performances & Trends Daily
September 18, 2025 - All trends (long term, mid-term and short term) for Biotech sector looks good.

The overall market intelligence score is 100 (0-bearish to 100-bullish) which puts Biotech sector in short term bullish trend.

The market intelligence score from previous trading session is 80 and hence an improvement of trend.

 Year To Date Performance: 5.15055 %
 Weekly Performance: 2.48136 %
 Daily Performance: 2.62344 %
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Biotech Sector Trend
100 / 100
Here are the market intelligence trend scores of the most requested Biotech stocks at 12Stocks.com (click stock name for detailed review):

12Stocks.com: Investing in Biotech sector with Stocks
The following table helps investors and traders sort through current performance and trends (as measured by market intelligence score) of various stocks in the Biotech sector.

Quick View: Move mouse or cursor over stock symbol (ticker) to view short-term Technical chart and over stock name to view long term chart. Click on to add stock symbol to your watchlist and to view watchlist. Click on any ticker or stock name for detailed market intelligence report for that stock.

12Stocks.com Performance of Stocks in Biotech Sector

TickerStock NameWatchlistCategoryRecent PriceMarket Intelligence ScoreChange %YTD Change%
PLXProtalix Bio Biotechnology1.87100-2.09-5.08%
QUREuniQure N.V Biotechnology14.1620-2.14-21.55%
VALNValneva SE Biotechnology8.6530-2.1583.26%
RIGLRigel  Biotechnology34.2230-2.1797.58%
OCULOcular Therapeutix Biotechnology12.1630-2.1739.19%
MDWDMediWound  Biotechnology16.7120-2.22-7.17%
CAPRCapricor  Biotechnology6.0810-2.25-59.36%
MDGLMadrigal  Biotechnology417.4330-2.2533.03%
IGMSIGM  Biotechnology1.2710-2.31-79.55%
ERASErasca  Biotechnology1.67100-2.34-38.15%
ARGXArgen X Biotechnology734.3540-2.3918.41%
HRTXHeron  Biotechnology1.2110-2.42-24.38%
RGNXRegenxbio  Biotechnology9.0340-2.4814.89%
AMAGAMAG  Biotechnology1.1710-2.500.00%
VKTXViking  Biotechnology23.0910-2.53-43.85%
CLLSCellectis ADR Biotechnology3.0880-2.5370.17%
HUMAHumacyte  Biotechnology1.5370-2.55-70.46%
PGNXProgenics  Biotechnology31.1170-2.630.00%
ZIOPZIOPHARM Oncology Biotechnology31.1170-2.630.00%
RXRXRecursion  Biotechnology4.7120-2.69-34.67%
MRVIMaravai Life Biotechnology2.8190-2.77-48.82%
OBIOOrchestra BioMed Biotechnology2.4610-2.77-54.28%
CMPXCompass  Biotechnology3.5150-2.77150.71%
IMRXImmuneering Corp Biotechnology8.0760-2.89265.16%
BMEABiomea Fusion Biotechnology1.9670-2.97-46.88%
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Performance: Year-to-date, Week and Day
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Detailed Overview of Biotech Stocks
Biotech Technical Overview, Leaders & Laggards, Top Biotech ETF Funds & Detailed Biotech Stocks List, Charts, Trends & More

Biotech Sector: Technical Analysis, Trends & YTD Performance
Biotech sector, as represented by XBI, an exchange-traded fund [ETF] that holds basket of Biotech stocks (e.g, Amgen, Celgene) is up by 5.15055% and is currently underperforming the overall market by -8.86965% year-to-date. Below is a quick view of Technical charts and trends:

XBI Weekly Chart
Long Term Trend: Very Good
Medium Term Trend: Very Good

XBI Daily Chart
Short Term Trend: Very Good
Overall Trend Score: 100
YTD Performance: 5.15055%
**Trend Scores & Views Are Only For Educational Purposes And Not For Investing


12Stocks.com: Top Performing Biotech Sector Stocks
Hot Biotech Stocks of 2025 We try to spot trends by analyzing the performances of various stocks or components within Biotech sector and try to find best performing stocks. The movers and shakers. The winners and losers.

The top performing Biotech sector stocks year to date are
Celcuity [316%] I-Mab ADR[307%] Galectin [292%]
Immuneering Corp[265%] Nektar [254%] Precigen [254%]
Nanobiotix ADR[252%] Gossamer Bio[208%] DBV Technologies[203%]
Monopar [200%] ATAI Life[194%]
View complete list of Biotech stocks by year-to-date performance

Now, more recently, over last week, the top performing Biotech sector stocks on the move are
Athersys [193287%] VBI Vaccines[86898.5%] ContraFect [47677.8%]
Clovis Oncology[39610.5%] NanoString Technologies[17224.7%] Neptune Wellness[14100%]
Achillion [10033.3%] Nymox [8258.5%] Epizyme [5739.5%]
Portola [4717.6%] Strongbridge Biopharma[3417.5%]
View complete list of Biotech stocks by weekly performance

Unfortunately not all Biotech stocks have done well this year. Investors of these stocks hope they have seen the worst and hope that these stocks are set to bounce back. The bearish stocks in this index year to date (YTD) are
Vaxxinity [-100%] Petros [-100%] Translate Bio[-95%]
Palatin Technologies[-93%] Syros [-91%] Pliant [-89%]
Affimed N.V[-87%] Unity nology[-86%] Sarepta [-84%]
IGM [-80%] Rocket [-76%] Allakos [-73%]
.
Investors can get enhanced performance by riding the current stock trends. Using complex algorithms, 12Stocks.com has come up with market intelligence scores (on 0-bearish to 100-bullish scale) to identify best trending stocks. Top trending Biotech stocks are
AlloVir [100] Monopar [100] Cara [100]
Corbus [100] Ocugen [100] Spruce [100]
Roivant [100] Xencor [100] Oncolytics [100]
Tango [100] Arcus [100] RAPT [100]
View complete list of Biotech stocks by 12Stocks.com trends

12Stocks.com: Investing in Biotech Sector using Exchange Traded Funds
The following table shows list of key exchange traded funds (ETF) that help investors track Biotech Index. For detailed view, check out our ETF Funds section of our website.

Quick View: Move mouse or cursor over ETF symbol (ticker) to view short-term Technical chart and over ETF name to view long term chart. Click on ticker or stock name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist.

12Stocks.com List of ETFs that track Biotech Index

TickerETF NameWatchlistRecent PriceMarket Intelligence ScoreChange %Week %Year-to-date %
UBIOBiotechnology  73.3480-0.0681292260.7480%
HCRFEdge Multifactor 67.142309999NA
SICKHealthcare Bear 3X 37.903609999NA
LABSBiotech Bear 1X 24.185609999NA
BTECPrincipal Healthcare Innovators 39.493001.023280%
 Market Intelligence Score (0-Bearish to 100-Bullish)
12Stocks.com: Charts, Trends, Fundamental Data and Performances of Biotech Stocks
We now take in-depth look at all Biotech stocks including charts, multi-period performances and overall trends (as measured by market intelligence score).

One can sort Biotech stocks (click link to choose) by Daily, Weekly and by Year-to-Date performances. Also, one can sort by size of the company or by market capitalization.
Select Your Default Chart Type:
Long Term Chart Daily Chart Weekly Chart 
Long Term Chart (Default)
Weekly Chart Example
Daily Chart Example
Click on stock symbol or name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist. Quick View: Move mouse or cursor over "Daily" to quickly view daily Technical stock chart and over "Weekly" to view weekly Technical stock chart.

Stock Chart of Protalix BioTherapeutics IncPLX Protalix BioTherapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 122.79 Millions
Recent Price: 1.87    
Market Intelligence Score: 100
Day Percent Change: -2.09424%    
Day Change: 0.01
Week Change: 19.1159%    
Year-to-date Change: -5.1%
PLX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PLX to Watchlist:       View:      Get Complete PLX Trend Analysis ➞

Stock Chart of uniQure N.VQURE uniQure N.V
Sector: Health Care
SubSector: Biotechnology
MarketCap: 984.86 Millions
Recent Price: 14.16    
Market Intelligence Score: 20
Day Percent Change: -2.14236%    
Day Change: 0.07
Week Change: -19.0395%    
Year-to-date Change: -21.6%
QURE Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add QURE to Watchlist:       View:      Get Complete QURE Trend Analysis ➞

Stock Chart of Valneva SE ADRVALN Valneva SE ADR
Sector: Health Care
SubSector: Biotechnology
MarketCap: 735.51 Millions
Recent Price: 8.65    
Market Intelligence Score: 30
Day Percent Change: -2.14932%    
Day Change: -0.31
Week Change: -22.6988%    
Year-to-date Change: 83.3%
VALN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add VALN to Watchlist:       View:      Get Complete VALN Trend Analysis ➞

Stock Chart of Rigel PharmaceuticalsRIGL Rigel Pharmaceuticals
Sector: Health Care
SubSector: Biotechnology
MarketCap: 741.53 Millions
Recent Price: 34.22    
Market Intelligence Score: 30
Day Percent Change: -2.17267%    
Day Change: 0.63
Week Change: -4.75925%    
Year-to-date Change: 97.6%
RIGL Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add RIGL to Watchlist:       View:      Get Complete RIGL Trend Analysis ➞

Stock Chart of Ocular Therapeutix IncOCUL Ocular Therapeutix Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 2366.34 Millions
Recent Price: 12.16    
Market Intelligence Score: 30
Day Percent Change: -2.17129%    
Day Change: 0.17
Week Change: -4.66301%    
Year-to-date Change: 39.2%
OCUL Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add OCUL to Watchlist:       View:      Get Complete OCUL Trend Analysis ➞

Stock Chart of MediWound LtdMDWD MediWound Ltd
Sector: Health Care
SubSector: Biotechnology
MarketCap: 176.06 Millions
Recent Price: 16.71    
Market Intelligence Score: 20
Day Percent Change: -2.22352%    
Day Change: -0.05
Week Change: 2.57827%    
Year-to-date Change: -7.2%
MDWD Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add MDWD to Watchlist:       View:      Get Complete MDWD Trend Analysis ➞

Stock Chart of Capricor Therapeutics IncCAPR Capricor Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 308.13 Millions
Recent Price: 6.08    
Market Intelligence Score: 10
Day Percent Change: -2.2508%    
Day Change: -0.16
Week Change: -6.17284%    
Year-to-date Change: -59.4%
CAPR Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CAPR to Watchlist:       View:      Get Complete CAPR Trend Analysis ➞

Stock Chart of Madrigal Pharmaceuticals IncMDGL Madrigal Pharmaceuticals Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 9648.69 Millions
Recent Price: 417.43    
Market Intelligence Score: 30
Day Percent Change: -2.25266%    
Day Change: 15.43
Week Change: -6.97524%    
Year-to-date Change: 33.0%
MDGL Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add MDGL to Watchlist:       View:      Get Complete MDGL Trend Analysis ➞

Stock Chart of IGM Biosciences, Inc.IGMS IGM Biosciences, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 2000.05 Millions
Recent Price: 1.27    
Market Intelligence Score: 10
Day Percent Change: -2.30769%    
Day Change: -9999
Week Change: -0.78125%    
Year-to-date Change: -79.5%
IGMS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add IGMS to Watchlist:       View:      Get Complete IGMS Trend Analysis ➞

Stock Chart of Erasca IncERAS Erasca Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 456.71 Millions
Recent Price: 1.67    
Market Intelligence Score: 100
Day Percent Change: -2.33918%    
Day Change: 0.04
Week Change: 3.72671%    
Year-to-date Change: -38.1%
ERAS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ERAS to Watchlist:       View:      Get Complete ERAS Trend Analysis ➞

Stock Chart of Argen X SE ADRARGX Argen X SE ADR
Sector: Health Care
SubSector: Biotechnology
MarketCap: 45947.7 Millions
Recent Price: 734.35    
Market Intelligence Score: 40
Day Percent Change: -2.38861%    
Day Change: 2.76
Week Change: -4.25684%    
Year-to-date Change: 18.4%
ARGX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ARGX to Watchlist:       View:      Get Complete ARGX Trend Analysis ➞

Stock Chart of Heron Therapeutics IncHRTX Heron Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 200.81 Millions
Recent Price: 1.21    
Market Intelligence Score: 10
Day Percent Change: -2.41935%    
Day Change: 0.02
Week Change: -6.92308%    
Year-to-date Change: -24.4%
HRTX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add HRTX to Watchlist:       View:      Get Complete HRTX Trend Analysis ➞

Stock Chart of Regenxbio IncRGNX Regenxbio Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 490.49 Millions
Recent Price: 9.03    
Market Intelligence Score: 40
Day Percent Change: -2.4838%    
Day Change: 0.04
Week Change: -8.69565%    
Year-to-date Change: 14.9%
RGNX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add RGNX to Watchlist:       View:      Get Complete RGNX Trend Analysis ➞

Stock Chart of AMAG Pharmaceuticals, Inc.AMAG AMAG Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 217.385 Millions
Recent Price: 1.17    
Market Intelligence Score: 10
Day Percent Change: -2.5%    
Day Change: -9999
Week Change: -71.9424%    
Year-to-date Change: 0.0%
AMAG Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add AMAG to Watchlist:       View:      Get Complete AMAG Trend Analysis ➞

Stock Chart of Viking Therapeutics IncVKTX Viking Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 3033.77 Millions
Recent Price: 23.09    
Market Intelligence Score: 10
Day Percent Change: -2.53271%    
Day Change: -0.03
Week Change: -8.62683%    
Year-to-date Change: -43.8%
VKTX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add VKTX to Watchlist:       View:      Get Complete VKTX Trend Analysis ➞

Stock Chart of Cellectis ADRCLLS Cellectis ADR
Sector: Health Care
SubSector: Biotechnology
MarketCap: 193.2 Millions
Recent Price: 3.08    
Market Intelligence Score: 80
Day Percent Change: -2.53165%    
Day Change: -0.05
Week Change: 8.07018%    
Year-to-date Change: 70.2%
CLLS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CLLS to Watchlist:       View:      Get Complete CLLS Trend Analysis ➞

Stock Chart of Humacyte IncHUMA Humacyte Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 226.47 Millions
Recent Price: 1.53    
Market Intelligence Score: 70
Day Percent Change: -2.54777%    
Day Change: -0.09
Week Change: 2%    
Year-to-date Change: -70.5%
HUMA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add HUMA to Watchlist:       View:      Get Complete HUMA Trend Analysis ➞

Stock Chart of Progenics Pharmaceuticals, Inc.PGNX Progenics Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 259.885 Millions
Recent Price: 31.11    
Market Intelligence Score: 70
Day Percent Change: -2.62911%    
Day Change: -9999
Week Change: 133.208%    
Year-to-date Change: 0.0%
PGNX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PGNX to Watchlist:       View:      Get Complete PGNX Trend Analysis ➞

Stock Chart of ZIOPHARM Oncology, Inc.ZIOP ZIOPHARM Oncology, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 614.785 Millions
Recent Price: 31.11    
Market Intelligence Score: 70
Day Percent Change: -2.62911%    
Day Change: -9999
Week Change: 137.463%    
Year-to-date Change: 0.0%
ZIOP Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ZIOP to Watchlist:       View:      Get Complete ZIOP Trend Analysis ➞

Stock Chart of Recursion Pharmaceuticals IncRXRX Recursion Pharmaceuticals Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 2003.8 Millions
Recent Price: 4.71    
Market Intelligence Score: 20
Day Percent Change: -2.68595%    
Day Change: 0.01
Week Change: 0.212766%    
Year-to-date Change: -34.7%
RXRX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add RXRX to Watchlist:       View:      Get Complete RXRX Trend Analysis ➞

Stock Chart of Maravai LifeSciences Holdings IncMRVI Maravai LifeSciences Holdings Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 640.96 Millions
Recent Price: 2.81    
Market Intelligence Score: 90
Day Percent Change: -2.76817%    
Day Change: -0.07
Week Change: 5.6391%    
Year-to-date Change: -48.8%
MRVI Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add MRVI to Watchlist:       View:      Get Complete MRVI Trend Analysis ➞

Stock Chart of Orchestra BioMed Holdings IncOBIO Orchestra BioMed Holdings Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 148.38 Millions
Recent Price: 2.46    
Market Intelligence Score: 10
Day Percent Change: -2.7668%    
Day Change: 0.06
Week Change: -9.22509%    
Year-to-date Change: -54.3%
OBIO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add OBIO to Watchlist:       View:      Get Complete OBIO Trend Analysis ➞

Stock Chart of Compass Therapeutics IncCMPX Compass Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 590.21 Millions
Recent Price: 3.51    
Market Intelligence Score: 50
Day Percent Change: -2.77008%    
Day Change: 0.02
Week Change: 0.862069%    
Year-to-date Change: 150.7%
CMPX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CMPX to Watchlist:       View:      Get Complete CMPX Trend Analysis ➞

Stock Chart of Immuneering CorpIMRX Immuneering Corp
Sector: Health Care
SubSector: Biotechnology
MarketCap: 200.12 Millions
Recent Price: 8.07    
Market Intelligence Score: 60
Day Percent Change: -2.88809%    
Day Change: 1.2
Week Change: 14.4681%    
Year-to-date Change: 265.2%
IMRX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add IMRX to Watchlist:       View:      Get Complete IMRX Trend Analysis ➞

Stock Chart of Biomea Fusion IncBMEA Biomea Fusion Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 114.26 Millions
Recent Price: 1.96    
Market Intelligence Score: 70
Day Percent Change: -2.9703%    
Day Change: 0.01
Week Change: 5.37634%    
Year-to-date Change: -46.9%
BMEA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add BMEA to Watchlist:       View:      Get Complete BMEA Trend Analysis ➞

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Performance: Year-to-date, Week and Day
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