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Best Biotech Stocks
Quick Read: Best Biotech Stocks List By Performances & Trends:
Daily, Weekly, Year-to-Date, Market Cap (Size) & Technical Trends
Best Biotech Stocks Views: Quick Browse View, Summary & Slide Show View

12Stocks.com: Investing in Biotech sector with Stocks
The following table helps investors and traders sort through current performance and trends (as measured by market intelligence score) of various stocks in the Biotech sector.

Quick View: Move mouse or cursor over stock symbol (ticker) to view short-term Technical chart and over stock name to view long term chart. Click on to add stock symbol to your watchlist and to view watchlist. Click on any ticker or stock name for detailed market intelligence report for that stock.

12Stocks.com Performance of Stocks in Biotech Sector

TickerStock NameWatchlistCategoryRecent PriceMarket Intelligence ScoreChange %YTD Change%
PRAXPraxis Precision Biotechnology45.9446-2.42-40.31%
RLAYRelay  Biotechnology3.2261-2.70-21.84%
MRVIMaravai Life Biotechnology2.2046-3.26-59.63%
ALXOALX Oncology Biotechnology0.6874-4.97-59.47%
LYRALyra  Biotechnology6.7041-5.64NA
PHATPhathom  Biotechnology9.7461-5.9819.95%
ARWRArrowhead  Biotechnology16.4246-9.86-12.66%
PTCTPTC  Biotechnology45.3863-12.480.53%
ARCTArcturus  Biotechnology11.9120-15.08-29.82%
MRNAModerna  Biotechnology26.1246-17.35-37.18%
BBIOBridgeBio Pharma Biotechnology46.5863-21.5469.75%
BIIBBiogen  Biotechnology130.6756-25.22-14.55%
XNCRXencor  Biotechnology7.2333-25.94-68.54%
ENTAEnanta  Biotechnology6.9046-29.3220.00%
AUPHAurinia  Biotechnology11.3773-30.3826.61%
ACADACADIA  Biotechnology24.6063-40.3434.06%
REPLReplimune  Biotechnology5.2910-42.49-56.32%
VRCAVerrica  Biotechnology6.3574-46.69807.14%
PRTAProthena  Biotechnology7.6973-64.38-44.48%
To view more stocks, click on Next / Previous arrows or select different range:
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Performance: Year-to-date, Week and Day
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Detailed Overview of Biotech Stocks
Biotech Technical Overview, Leaders & Laggards, Top Biotech ETF Funds & Detailed Biotech Stocks List, Charts, Trends & More

Biotech Sector: Technical Analysis, Trends & YTD Performance
Biotech sector, as represented by XBI, an exchange-traded fund [ETF] that holds basket of Biotech stocks (e.g, Amgen, Celgene) is down by % and is currently underperforming the overall market by -8.39% year-to-date. Below is a quick view of Technical charts and trends:

Weekly Chart

Daily Chart
Overall Trend Score:
YTD Performance: %
**Trend Scores & Views Are Only For Educational Purposes And Not For Investing


12Stocks.com: Top Performing Biotech Sector Stocks
Hot Biotech Stocks of 2025 We try to spot trends by analyzing the performances of various stocks or components within Biotech sector and try to find best performing stocks. The movers and shakers. The winners and losers.

The top performing Biotech sector stocks year to date are
Lyra [3146%] Nektar [2380%] Lyell Immunopharma[1616%]
Verrica [807%] RAPT [521%] Mersana [341%]
Generation Bio[287%] Galectin [222%] Tango [114%]
Adaptive nologies[104%] X4 [103%] Lineage Cell[96%]
View complete list of Biotech stocks by year-to-date performance

Now, more recently, over last week, the top performing Biotech sector stocks on the move are
Y-mAbs [87.9%] Alector [48.3%] Rigel [44.7%]
SIGA Technologies[38.7%] Esperion [33.6%] ALX Oncology[30.6%]
Avidity [28.9%] Novavax [27.6%] ANI [27.5%]
Syndax [25.1%] Ardelyx [20.3%] Puma nology[20.2%]
View complete list of Biotech stocks by weekly performance

Unfortunately not all Biotech stocks have done well this year. Investors of these stocks hope they have seen the worst and hope that these stocks are set to bounce back. The bearish stocks in this index year to date (YTD) are
Pliant [-87%] Sarepta [-85%] Acrivon [-79%]
IGM [-79%] Rocket [-77%] PepGen [-72%]
Iovance Bio[-71%] Entrada [-70%] Xencor [-69%]
Arvinas [-67%] Geron [-64%] Vaxcyte [-63%]
.
Investors can get enhanced performance by riding the current stock trends. Using complex algorithms, 12Stocks.com has come up with market intelligence scores (on 0-bearish to 100-bullish scale) to identify best trending stocks. Top trending Biotech stocks are
Precigen [78] Greenwich Life[78] Arcutis Bio[74]
Mersana [74] MacroGenics [74] Esperion [74]
yte [74] ALX Oncology[74] Verrica [74]
Summit [73] XOMA [73] Wave Life[73]
View complete list of Biotech stocks by 12Stocks.com trends

12Stocks.com: Investing in Biotech Sector using Exchange Traded Funds
The following table shows list of key exchange traded funds (ETF) that help investors track Biotech Index. For detailed view, check out our ETF Funds section of our website.

Quick View: Move mouse or cursor over ETF symbol (ticker) to view short-term Technical chart and over ETF name to view long term chart. Click on ticker or stock name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist.

12Stocks.com List of ETFs that track Biotech Index

TickerETF NameWatchlistRecent PriceMarket Intelligence ScoreChange %Week %Year-to-date %
IBBBiotechnology  132.046616.19-0.75-0.04%
IHFHealthcare Providers  42.62201.484.44-11.01%
CUREHealthcare Bull 3X 69.313333.21-2.7-24.66%
IXJGlobal Healthcare  83.35280.87-0.26-3.05%
ZBIOShort Biotech 14.63170-5.0678.63%
BBHBiotech  159.346913.23-1.991.51%
BIBBiotechnology  50.80812.26-0.430.52%
BISShort Biotech 15.7318-1.90.19-12.85%
 Market Intelligence Score (0-Bearish to 100-Bullish)
12Stocks.com: Charts, Trends, Fundamental Data and Performances of Biotech Stocks
We now take in-depth look at all Biotech stocks including charts, multi-period performances and overall trends (as measured by market intelligence score).

One can sort Biotech stocks (click link to choose) by Daily, Weekly and by Year-to-Date performances. Also, one can sort by size of the company or by market capitalization.
Select Your Default Chart Type:
Long Term Chart Daily Chart Weekly Chart 
Long Term Chart (Default)
Weekly Chart Example
Daily Chart Example
Click on stock symbol or name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist. Quick View: Move mouse or cursor over "Daily" to quickly view daily Technical stock chart and over "Weekly" to view weekly Technical stock chart.

Stock Chart of Praxis Precision Medicines, Inc.PRAX Praxis Precision Medicines, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 16587 Millions
Recent Price: 45.94    
Market Intelligence Score: 46
Day Percent Change: -2.42%    
Day Change: -1.25
Week Change: -15.07%    
Year-to-date Change: -40.3%
PRAX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PRAX to Watchlist:       View:      Get Complete PRAX Trend Analysis ➞

Stock Chart of Relay Therapeutics, Inc.RLAY Relay Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 45887 Millions
Recent Price: 3.22    
Market Intelligence Score: 61
Day Percent Change: -2.7%    
Day Change: -0.2
Week Change: -4.17%    
Year-to-date Change: -21.8%
RLAY Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add RLAY to Watchlist:       View:      Get Complete RLAY Trend Analysis ➞

Stock Chart of Maravai LifeSciences Holdings, Inc.MRVI Maravai LifeSciences Holdings, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 67887 Millions
Recent Price: 2.20    
Market Intelligence Score: 46
Day Percent Change: -3.26%    
Day Change: -0.3
Week Change: -0.9%    
Year-to-date Change: -59.6%
MRVI Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add MRVI to Watchlist:       View:      Get Complete MRVI Trend Analysis ➞

Stock Chart of ALX Oncology Holdings Inc.ALXO ALX Oncology Holdings Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 41787 Millions
Recent Price: 0.68    
Market Intelligence Score: 74
Day Percent Change: -4.97%    
Day Change: -0.13
Week Change: 30.63%    
Year-to-date Change: -59.5%
ALXO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ALXO to Watchlist:       View:      Get Complete ALXO Trend Analysis ➞

Stock Chart of Lyra Therapeutics, Inc.LYRA Lyra Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 12487 Millions
Recent Price: 6.70    
Market Intelligence Score: 41
Day Percent Change: -5.64%    
Day Change: -0.02
Week Change: 1.82%    
Year-to-date Change: 3,146.1%
LYRA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add LYRA to Watchlist:       View:      Get Complete LYRA Trend Analysis ➞

Stock Chart of Phathom Pharmaceuticals, Inc.PHAT Phathom Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 728.785 Millions
Recent Price: 9.74    
Market Intelligence Score: 61
Day Percent Change: -5.98%    
Day Change: -0.88
Week Change: 16.65%    
Year-to-date Change: 20.0%
PHAT Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PHAT to Watchlist:       View:      Get Complete PHAT Trend Analysis ➞

Stock Chart of Arrowhead Pharmaceuticals, Inc.ARWR Arrowhead Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 3226.15 Millions
Recent Price: 16.42    
Market Intelligence Score: 46
Day Percent Change: -9.86%    
Day Change: -2.71
Week Change: 3.08%    
Year-to-date Change: -12.7%
ARWR Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ARWR to Watchlist:       View:      Get Complete ARWR Trend Analysis ➞

Stock Chart of PTC Therapeutics, Inc.PTCT PTC Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 2795.85 Millions
Recent Price: 45.38    
Market Intelligence Score: 63
Day Percent Change: -12.48%    
Day Change: -4.87
Week Change: -12.95%    
Year-to-date Change: 0.5%
PTCT Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PTCT to Watchlist:       View:      Get Complete PTCT Trend Analysis ➞

Stock Chart of Arcturus Therapeutics Holdings Inc.ARCT Arcturus Therapeutics Holdings Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 241.385 Millions
Recent Price: 11.91    
Market Intelligence Score: 20
Day Percent Change: -15.08%    
Day Change: -3.88
Week Change: -3.17%    
Year-to-date Change: -29.8%
ARCT Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ARCT to Watchlist:       View:      Get Complete ARCT Trend Analysis ➞

Stock Chart of Moderna, Inc.MRNA Moderna, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 11006.4 Millions
Recent Price: 26.12    
Market Intelligence Score: 46
Day Percent Change: -17.35%    
Day Change: -17.3
Week Change: -5.38%    
Year-to-date Change: -37.2%
MRNA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add MRNA to Watchlist:       View:      Get Complete MRNA Trend Analysis ➞

Stock Chart of BridgeBio Pharma, Inc.BBIO BridgeBio Pharma, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 3879.35 Millions
Recent Price: 46.58    
Market Intelligence Score: 63
Day Percent Change: -21.54%    
Day Change: -6.95
Week Change: -1.67%    
Year-to-date Change: 69.8%
BBIO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add BBIO to Watchlist:       View:      Get Complete BBIO Trend Analysis ➞

Stock Chart of Biogen Inc.BIIB Biogen Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 53102.6 Millions
Recent Price: 130.67    
Market Intelligence Score: 56
Day Percent Change: -25.22%    
Day Change: -69.14
Week Change: -0.97%    
Year-to-date Change: -14.6%
BIIB Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add BIIB to Watchlist:       View:      Get Complete BIIB Trend Analysis ➞

Stock Chart of Xencor, Inc.XNCR Xencor, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1744.35 Millions
Recent Price: 7.23    
Market Intelligence Score: 33
Day Percent Change: -25.94%    
Day Change: -6.19
Week Change: -9.4%    
Year-to-date Change: -68.5%
XNCR Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add XNCR to Watchlist:       View:      Get Complete XNCR Trend Analysis ➞

Stock Chart of Enanta Pharmaceuticals, Inc.ENTA Enanta Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 998.385 Millions
Recent Price: 6.90    
Market Intelligence Score: 46
Day Percent Change: -29.32%    
Day Change: -5.43
Week Change: -2.95%    
Year-to-date Change: 20.0%
ENTA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ENTA to Watchlist:       View:      Get Complete ENTA Trend Analysis ➞

Stock Chart of Aurinia Pharmaceuticals Inc.AUPH Aurinia Pharmaceuticals Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1319.75 Millions
Recent Price: 11.37    
Market Intelligence Score: 73
Day Percent Change: -30.38%    
Day Change: -2.95
Week Change: 8.39%    
Year-to-date Change: 26.6%
AUPH Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add AUPH to Watchlist:       View:      Get Complete AUPH Trend Analysis ➞

Stock Chart of ACADIA Pharmaceuticals Inc.ACAD ACADIA Pharmaceuticals Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 5400.35 Millions
Recent Price: 24.60    
Market Intelligence Score: 63
Day Percent Change: -40.34%    
Day Change: -10.78
Week Change: 4.55%    
Year-to-date Change: 34.1%
ACAD Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ACAD to Watchlist:       View:      Get Complete ACAD Trend Analysis ➞

Stock Chart of Replimune Group, Inc.REPL Replimune Group, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 367.885 Millions
Recent Price: 5.29    
Market Intelligence Score: 10
Day Percent Change: -42.49%    
Day Change: -7.78
Week Change: -30.39%    
Year-to-date Change: -56.3%
REPL Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add REPL to Watchlist:       View:      Get Complete REPL Trend Analysis ➞

Stock Chart of Verrica Pharmaceuticals Inc.VRCA Verrica Pharmaceuticals Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 289.585 Millions
Recent Price: 6.35    
Market Intelligence Score: 74
Day Percent Change: -46.69%    
Day Change: -2.47
Week Change: 12.59%    
Year-to-date Change: 807.1%
VRCA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add VRCA to Watchlist:       View:      Get Complete VRCA Trend Analysis ➞

Stock Chart of Prothena Corporation plcPRTA Prothena Corporation plc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 357.985 Millions
Recent Price: 7.69    
Market Intelligence Score: 73
Day Percent Change: -64.38%    
Day Change: -39.24
Week Change: 12.92%    
Year-to-date Change: -44.5%
PRTA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PRTA to Watchlist:       View:      Get Complete PRTA Trend Analysis ➞

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Click To Change The Sort Order: By Market Cap or Company Size
Performance: Year-to-date, Week and Day
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Biotech Stocks With Best Up Trends [0-bearish to 100-bullish]:
Precigen [78], Greenwich Life[78], Arcutis Bio[74], Mersana [74], MacroGenics [74], Esperion [74], yte [74], ALX Oncology[74], Verrica [74], Summit [73], XOMA [73]

Best Biotech Stocks Year-to-Date:
Lyra [3146.12%], Nektar [2379.57%], Lyell Immunopharma[1615.63%], Verrica [807.14%], RAPT [520.89%], Mersana [340.56%], Generation Bio[286.79%], Galectin [221.71%], Tango [113.92%], Adaptive nologies[103.5%], X4 [103%]

Best Biotech Stocks This Week:
Y-mAbs [87.86%], Alector [48.28%], Rigel [44.68%], SIGA Technologies[38.7%], Esperion [33.57%], ALX Oncology[30.63%], Avidity [28.87%], Novavax [27.59%], ANI [27.45%], Syndax [25.05%], Ardelyx [20.32%]

Best Biotech Stocks Daily:
Corbus [827.02%], Summit [647.43%], Applied [270.13%], Crinetics [209.71%], TG [153.47%], Arbutus Biopharma[91.63%], XOMA [80.51%], Cytokinetics [79.41%], Iovance Bio[66.25%], Novavax [65.84%], Mirum [64.05%]


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