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Stock Charts, Performance & Trend Analysis for IONS
Ionis Pharmaceuticals Inc

IONS
Year-to-Date: 76.8%
This Week: 0.6%
IONS Stock Charts
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barchart of year-to-date performances

IONS
Year-to-Date (YTD) Return: 76.7656%
 
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Long Term Trend: Very Good
Medium Term Trend: Good
Short Term Trend: Not Good
Ionis
Overall Trend Score:
60 Out Of 100
Bottomline: Neutral to Bullish Trend


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September 17, 2025 - The year-to-date (YTD) return or performance of Ionis (IONS) is up 76.7656% and is outperforming the overall stock market by 64.1478%.

Recently, the weekly return of Ionis (IONS) is up 0.55756% but is underperforming the overall market by -0.271152%.

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Although long and mid term trends for Ionis Pharmaceuticals Inc looks good, the short term trends are deteriorating.

The overall 12Stocks.com Smart Investing & Trading Score is 60 (measures stock trend from 0-bearish to 100-bullish) which puts IONS in short term neutral to bullish trend.

The Smart Investing & Trading Score from previous trading session is 80 and a deterioration of trend continues. Scroll down for key technical charts, support & resistance levels and analysis for Ionis.

Stock Analysis for IONS
Name: Ionis Pharmaceuticals Inc
Sector: Health Care
SubSector: Biotechnology
In A Glance
Ionis (IONS) Stock Performance and Technical Trend Chart View
 
IONS Recent Price: 61.32    
MarketCap: 9773.88 Millions
Day Percent Change: 0.360065%
Day Change: -1.98
Week Change: 0.55756%
Year-to-date Change: 76.7656%
Weekly IONS Technical Chart


Daily IONS Technical Chart
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Short Term Trend Analysis for IONS
 
60 / 100
The current technical trend score is 60 in a scale where 0 is bearish and 100 is bullish.
The technical trend score from previous session is 60.
Trend score updated daily. Not to be used for investing.

Stocks Similar To Ionis


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IONS Related Pages
Top Health Care Stocks ➞
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Compare IONS's Trend (60) with trends of related stocks
Vertex 10
Celgene 20
Poseida 50
Regeneron 90
Alnylam 50
Lilly(Eli) & Co 70
Johnson & Johnson 70
Abbvie Inc 100
Unitedhealth 60
Astrazeneca 30
Novartis AG 20
Abbott 60
Merck & Co Inc 50
Thermo Fisher 30
Novo Nordisk 80

The table below shows stocks similar to Ionis Pharmaceuticals Inc, i.e, from same subsector or sector along with year-to-date (76.8% YTD), weekly (0.6%) & daily performaces for comparison. Usually, stocks from similar sector tend to move together but companies that have innovative products, services or good management tend to outperform. Compare 12Stocks.com Smart Investing & Trading Scores to see which stocks in this sector are trending better currently. Click on ticker or stock name for detailed view (place cursor on ticker or stock name to view charts quickly). Click on to add stock symbol to your watchlist and to view watchlist.
Don't forget to get complete 360o overview of best moving sectors
& stocks daily here at 12Stocks.com ➞
TickerStock NameWatchlistCategoryRecent PriceSmart Investing & Trading Score
[0 to 100]
Change %Weekly Change%YTD Change%
VRTXVertex  Biotechnology388.6110-0.70-2.0-4.23%
CELGCelgene  Biotechnology55.13201.30-27.70.00%
PSTXPoseida  Biotechnology9.5050-0.630.81.06%
REGNRegeneron  Biotechnology581.64901.144.5-18.45%
ALNYAlnylam  Biotechnology456.5850-1.01-2.068.29%
INZYInozyme Pharma Biotechnology4.00500.000.340.35%
SPRBSpruce  Biotechnology11.3910012.4939.3-63.79%
ARGXArgen X Biotechnology752.3270-0.60-2.021.31%
INSMInsmed Inc Biotechnology144.75401.12-1.3106.93%
BNTXBioNTech SE Biotechnology99.26301.41-3.3-13.91%
ALVRAlloVir  Biotechnology11.4710016.9220.910.82%
CERECerevel  Biotechnology44.96500.003.70.00%
PTPIPetros  Biotechnology0.030-4.76-6.7-99.76%
RPRXRoyalty Pharma Biotechnology35.62200.56-2.439.96%
ALXNAlexion  Biotechnology834.36901.91357.20.00%
SMMTSummit  Biotechnology18.1230-4.33-6.8-1.25%
SGENSeattle Genetics Biotechnology202.14301.63-8.80.00%
KRONKronos Bio Biotechnology0.88401.490.9-9.29%
GMABGenmab ADR Biotechnology28.24800.892.534.48%
INCYIncyte Corp Biotechnology85.54801.95-0.123.03%
ASNDAscendis Pharma Biotechnology197.24701.34-3.942.92%
BMRNBiomarin  Biotechnology54.51501.060.8-13.97%
BGNEBeiGene  Biotechnology184.71400.494.70.00%
BBIOBridgeBio Pharma Biotechnology51.49600.04-5.282.59%
EXELExelixis Inc Biotechnology40.62803.783.822.53%
LLYLilly(Eli) & Co Drugs762.9970-0.221.6-1.57%
JNJJohnson & Johnson Drugs177.18700.410.125.07%
ABBVAbbvie Inc Drugs220.831002.114.926.46%
UNHUnitedhealth  Insurance339.3460-0.13-2.5-31.97%
AZNAstrazeneca  Drugs77.58300.03-4.520.22%
NVSNovartis AG Drugs122.5420-0.20-4.330.69%
ABTAbbott  Instrument133.90600.861.519.74%


Technical Levels: For the trading inclined, the following are the key levels of resistance (ceiling) and support (floor) for IONS. Ceiling and floor levels are stock prices at which the stock trend gets resistance or support respectively. Stocks & their trends tend to pause at these levels and hence traders have an eye on them.

Long term levels are more important. Stocks that have broken thru their resistance or support levels convincingly tend to have stronger trends (confirm with charts above visually).
Key Technical Levels for IONS
 Short TermWeeklyLong Term
Resistance (Ceiling)43.2643.8245.66
Support (Floor)41.9640.3739.72

        
RELATIVE PERFORMANCE OF
Ionis Pharmaceuticals Inc
Vs
THE MARKET
Relative performance of Ionis Pharmaceuticals Inc Compared to Overall Market
How is IONS faring versus the market [S&P 500] ? Is it lagging or leading ? How is its relative performance ?
Symbol Day Change Week Change Year-to-Date Change
SPY -0.556153% 0.828712% 12.6178%
IONS 0.360065% 0.55756% 76.7656%

IONS Chart

S&P 500 (Market) Chart
Year to date returns, IONS is outperforming the market by 64.1478%
This week, IONS is underperforming the market by -0.271152%


        
Performance of Ionis Pharmaceuticals Inc vs Health Care ETF RELATIVE PERFORMANCE OF
Ionis Pharmaceuticals Inc
Vs
Health Care Sector
Let us compare apples to apples and compare performance of IONS with its sector ETF (contains basket of stocks of same sector) XLV [Health Care SPDR] ?
Symbol Day Change Week Change Year-to-Date Change
XLV 0.153363 % -1.04625 % 0.521887 %
IONS 0.360065% 0.55756% 76.7656%

IONS Chart

Health Care Chart
Year to date, IONS is outperforming Health Care sector by 76.243713%
This week, IONS is outperforming Health Care sector by 1.60381%

List Of ETF Funds Related To Ionis Pharmaceuticals Inc

The table below shows ETFs (Exchange Traded Funds) similar to Ionis Pharmaceuticals Inc, i.e, from same sector along with year-to-date (YTD), weekly & daily performaces for comparison. Usually, ETFs and associated stocks from similar sector tend to move together but companies that have innovative products, services or good management tend to outperform. Move mouse or cursor over ETF symbol to view short-term technical chart and over ETF name to view long term chart. Click on to add ETF symbol to your watchlist and to view watchlist.
TickerStock NameWatchlistCategoryRecent PriceChange %Weekly Change%YTD Change%
BBHBiotech HOLDRs Health Care166.50.590.480.76%
IBBiShares Nasdaq Biotechnology Health Care140.940.156339-0.8930456.13591%
RXLProShares Ultra HealthCare  Health Care41.621.24-0.67-15.94%
PPHPharmaceutical HOLDRs Health Care88.60.2-0.530.91%
RXDProShares UltraShort HealthCare  Health Care11.77-0.7437891.64076-1.09244%
XLVHealth Care SPDR Health Care137.140.153363-1.046250.521887%
IXJiShares Global Healthcare  Health Care87.560.183066-0.8268212.6945%
IHFiShares U. S. Healthcare Providers Health Care47.910.31407-1.257210.480275%
XBISPDR Biotech Health Care94.070.352038-0.9580962.79032%
PBEPowerShares Biotech  Health Care69.680.114943-1.542984.09975%
FBTFT Biotech Index Fund Health Care176.850.792203-0.07345466.08878%
IYHiShares US Healthcare Health Care57.61-0.311473-1.01375-0.696726%
VHTVanguard Health Care VIPERS Health Care254.810.0392603-0.7478671.0385%
PJPPowerShares Pharmaceuticals Health Care90.83-0.0879991-1.6246110.1522%
IHIiShares U.S. Medical Devices Health Care60.350.0165728-3.486333.63166%
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