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Best Biotech Stocks

Quick Read: Best Biotech Stocks List By Performances & Trends:
Daily, Weekly, Year-to-Date, Market Cap (Size) & Technical Trends
Best Biotech Stocks Views: Quick Browse View, Summary & Slide Show View

12Stocks.com Biotech Stocks Performances & Trends Daily
September 2, 2025 - Although long and mid term trends for Biotech sector looks good, the short term trends are deteriorating.

The overall market intelligence score is 60 (0-bearish to 100-bullish) which puts Biotech sector in short term neutral to bullish trend.

The market intelligence score from previous trading session is 60 and an improvement of trend continues.

 Year To Date Performance: -0.67 %
 Weekly Performance: 2.44 %
 Daily Performance: 2.44 %
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Biotech Sector Trend
60 / 100
Here are the market intelligence trend scores of the most requested Biotech stocks at 12Stocks.com (click stock name for detailed review):

12Stocks.com: Investing in Biotech sector with Stocks
The following table helps investors and traders sort through current performance and trends (as measured by market intelligence score) of various stocks in the Biotech sector.

Quick View: Move mouse or cursor over stock symbol (ticker) to view short-term Technical chart and over stock name to view long term chart. Click on to add stock symbol to your watchlist and to view watchlist. Click on any ticker or stock name for detailed market intelligence report for that stock.

12Stocks.com Performance of Stocks in Biotech Sector

TickerStock NameWatchlistCategoryRecent PriceMarket Intelligence ScoreChange %YTD Change%
SLGLSol-Gel Technologies Biotechnology22.796040.22177.39%
IMRXImmuneering  Biotechnology5.759034.99110.45%
ALXOALX Oncology Biotechnology1.1710023.80-38.32%
TYRATyra  Biotechnology12.677114.26-15.83%
NBTXNanobiotix S.A Biotechnology8.959014.15239.28%
ZNTLZentalis  Biotechnology1.696014.02-38.28%
ZURAZura Bio Biotechnology2.045113.71-20.40%
XFORX4  Biotechnology3.756013.57-85.56%
PGENPrecigen  Biotechnology4.5110013.40225.00%
GOSSGossamer Bio Biotechnology2.477011.28139.89%
MRSNMersana  Biotechnology7.324011.25-77.31%
ALGSAligos  Biotechnology10.557011.19-75.30%
QSIQuantum-Si  Biotechnology1.132011.00-58.89%
ATAIAtai Life Biotechnology4.588010.58230.08%
TRDAEntrada  Biotechnology5.472510.55-66.05%
APLMApollomics  Biotechnology3.936810.00-37.95%
FBIOFortress  Biotechnology2.581009.2710.34%
CASICASI  Biotechnology2.31808.33-12.72%
ANIKAnika  Biotechnology9.38708.12-45.02%
DSGNDesign  Biotechnology5.531007.52-16.53%
TERNTerns  Biotechnology6.96807.3022.02%
OMEROmeros  Biotechnology4.16306.92-54.66%
REPLReplimune  Biotechnology5.40206.67-53.76%
KROSKeros  Biotechnology15.21806.61-4.17%
NCNANuCana  Biotechnology3.19306.43-98.61%
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Performance: Year-to-date, Week and Day
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Detailed Overview of Biotech Stocks
Biotech Technical Overview, Leaders & Laggards, Top Biotech ETF Funds & Detailed Biotech Stocks List, Charts, Trends & More

Biotech Sector: Technical Analysis, Trends & YTD Performance
Biotech sector, as represented by XBI, an exchange-traded fund [ETF] that holds basket of Biotech stocks (e.g, Amgen, Celgene) is down by -0.67% and is currently underperforming the overall market by -6.35% year-to-date. Below is a quick view of Technical charts and trends:

XBI Weekly Chart
Long Term Trend: Very Good
Medium Term Trend: Good

XBI Daily Chart
Short Term Trend: Not Good
Overall Trend Score: 60
YTD Performance: -0.67%
**Trend Scores & Views Are Only For Educational Purposes And Not For Investing


12Stocks.com: Top Performing Biotech Sector Stocks
Hot Biotech Stocks of 2025 We try to spot trends by analyzing the performances of various stocks or components within Biotech sector and try to find best performing stocks. The movers and shakers. The winners and losers.

The top performing Biotech sector stocks year to date are
I Mab[454%] Matinas BioPharma[241%] Nanobiotix S.A[239%]
Atai Life[230%] Precigen [225%] DBV Technologies[209%]
Galectin [201%] Sol-Gel Technologies[177%] Rigel [150%]
Gossamer Bio[140%] Lineage Cell[133%] Tango [127%]
View complete list of Biotech stocks by year-to-date performance

Now, more recently, over last week, the top performing Biotech sector stocks on the move are
Precigen [96.8%] Sol-Gel Technologies[69.2%] ALX Oncology[57.3%]
Immuneering [52.3%] Minerva Neuro[34.5%] Aligos [29.7%]
Karyopharm [29.5%] CASI [27.3%] Zentalis [26.4%]
Rocket [23.1%] Tenaya [22.5%] Nanobiotix S.A[18.8%]
View complete list of Biotech stocks by weekly performance

Unfortunately not all Biotech stocks have done well this year. Investors of these stocks hope they have seen the worst and hope that these stocks are set to bounce back. The bearish stocks in this index year to date (YTD) are
NuCana [-99%] ADiTx [-98%] Adaptimmune [-89%]
Pliant [-89%] X4 [-86%] Sarepta [-84%]
Mustang Bio[-81%] RedHill Biopharma[-79%] Acrivon [-78%]
Mersana [-77%] Aligos [-75%] Rocket [-70%]
.
Investors can get enhanced performance by riding the current stock trends. Using complex algorithms, 12Stocks.com has come up with market intelligence scores (on 0-bearish to 100-bullish scale) to identify best trending stocks. Top trending Biotech stocks are
ALX Oncology[100] Precigen [100] Fortress [100]
Design [100] Kura Oncology[100] FibroGen [100]
Madrigal [100] Nektar [100] Arcus [100]
Pharming [100] Inovio [100] BridgeBio Pharma[100]
View complete list of Biotech stocks by 12Stocks.com trends

12Stocks.com: Investing in Biotech Sector using Exchange Traded Funds
The following table shows list of key exchange traded funds (ETF) that help investors track Biotech Index. For detailed view, check out our ETF Funds section of our website.

Quick View: Move mouse or cursor over ETF symbol (ticker) to view short-term Technical chart and over ETF name to view long term chart. Click on ticker or stock name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist.

12Stocks.com List of ETFs that track Biotech Index

TickerETF NameWatchlistRecent PriceMarket Intelligence ScoreChange %Week %Year-to-date %
LABDBiotech Bear 3X 5.7550-2.55-1.37-19.84%
XBIBiotech  92.04602.442.44-0.67%
IBBBiotechnology  138.22700.730.730.89%
LABUBiotech Bull 3X 69.35702.380.61-22.08%
IYHHealthcare  57.8790-0.312.14-0.44%
IHFHealthcare Providers  47.39700.340.34-9.95%
CUREHealthcare Bull 3X 80.6780-1.026.93-12.21%
ZBIOShort Biotech 16.00603.741.01106.72%
IXJGlobal Healthcare  87.66900.821.4-2.62%
BBCBio Biotechnology Clinical 22.70602.050.29-5.46%
FBTFirst NYSE 171.9880-0.150.664.14%
BIBBiotechnology  55.26501.032.4711.53%
BBHBiotech  165.18700.610.531.51%
BISShort Biotech 14.4250-0.99-2.37-20.83%
PBEBiotech & Genome 68.45900.311.642.9%
BBPBio Biotechnology Products 67.32600.761.0512.25%
PTHDWA Healthcare Momentum 39.81700.670.47-1.58%
 Market Intelligence Score (0-Bearish to 100-Bullish)
12Stocks.com: Charts, Trends, Fundamental Data and Performances of Biotech Stocks
We now take in-depth look at all Biotech stocks including charts, multi-period performances and overall trends (as measured by market intelligence score).

One can sort Biotech stocks (click link to choose) by Daily, Weekly and by Year-to-Date performances. Also, one can sort by size of the company or by market capitalization.
Select Your Default Chart Type:
Long Term Chart Daily Chart Weekly Chart 
Long Term Chart (Default)
Weekly Chart Example
Daily Chart Example
Click on stock symbol or name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist. Quick View: Move mouse or cursor over "Daily" to quickly view daily Technical stock chart and over "Weekly" to view weekly Technical stock chart.

Stock Chart of Sol-Gel Technologies Ltd.SLGL Sol-Gel Technologies Ltd.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 183.285 Millions
Recent Price: 22.79    
Market Intelligence Score: 60
Day Percent Change: 40.22%    
Day Change: 7.4
Week Change: 69.18%    
Year-to-date Change: 177.4%
SLGL Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add SLGL to Watchlist:       View:      Get Complete SLGL Trend Analysis ➞

Stock Chart of Immuneering CorporationIMRX Immuneering Corporation
Sector: Health Care
SubSector: Biotechnology
MarketCap: 303 Millions
Recent Price: 5.75    
Market Intelligence Score: 90
Day Percent Change: 34.99%    
Day Change: 1.2
Week Change: 52.3%    
Year-to-date Change: 110.5%
IMRX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add IMRX to Watchlist:       View:      Get Complete IMRX Trend Analysis ➞

Stock Chart of ALX Oncology Holdings Inc.ALXO ALX Oncology Holdings Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 41787 Millions
Recent Price: 1.17    
Market Intelligence Score: 100
Day Percent Change: 23.8%    
Day Change: 0.2
Week Change: 57.25%    
Year-to-date Change: -38.3%
ALXO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ALXO to Watchlist:       View:      Get Complete ALXO Trend Analysis ➞

Stock Chart of Tyra Biosciences, Inc.TYRA Tyra Biosciences, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 732 Millions
Recent Price: 12.67    
Market Intelligence Score: 71
Day Percent Change: 14.26%    
Day Change: 1.46
Week Change: 9.35%    
Year-to-date Change: -15.8%
TYRA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add TYRA to Watchlist:       View:      Get Complete TYRA Trend Analysis ➞

Stock Chart of Nanobiotix S.A.NBTX Nanobiotix S.A.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 177 Millions
Recent Price: 8.95    
Market Intelligence Score: 90
Day Percent Change: 14.15%    
Day Change: 1.21
Week Change: 18.75%    
Year-to-date Change: 239.3%
NBTX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add NBTX to Watchlist:       View:      Get Complete NBTX Trend Analysis ➞

Stock Chart of Zentalis Pharmaceuticals, Inc.ZNTL Zentalis Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 22187 Millions
Recent Price: 1.69    
Market Intelligence Score: 60
Day Percent Change: 14.02%    
Day Change: 0.23
Week Change: 26.35%    
Year-to-date Change: -38.3%
ZNTL Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ZNTL to Watchlist:       View:      Get Complete ZNTL Trend Analysis ➞

Stock Chart of Zura Bio LimitedZURA Zura Bio Limited
Sector: Health Care
SubSector: Biotechnology
MarketCap: 242 Millions
Recent Price: 2.04    
Market Intelligence Score: 51
Day Percent Change: 13.71%    
Day Change: 0.24
Week Change: 15.7%    
Year-to-date Change: -20.4%
ZURA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ZURA to Watchlist:       View:      Get Complete ZURA Trend Analysis ➞

Stock Chart of X4 Pharmaceuticals, Inc.XFOR X4 Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 143.385 Millions
Recent Price: 3.75    
Market Intelligence Score: 60
Day Percent Change: 13.57%    
Day Change: 0.38
Week Change: 1.27%    
Year-to-date Change: -85.6%
XFOR Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add XFOR to Watchlist:       View:      Get Complete XFOR Trend Analysis ➞

Stock Chart of Precigen, Inc.PGEN Precigen, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 564.785 Millions
Recent Price: 4.51    
Market Intelligence Score: 100
Day Percent Change: 13.4%    
Day Change: 0.43
Week Change: 96.76%    
Year-to-date Change: 225.0%
PGEN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PGEN to Watchlist:       View:      Get Complete PGEN Trend Analysis ➞

Stock Chart of Gossamer Bio, Inc.GOSS Gossamer Bio, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 653.285 Millions
Recent Price: 2.47    
Market Intelligence Score: 70
Day Percent Change: 11.28%    
Day Change: 0.22
Week Change: 10.71%    
Year-to-date Change: 139.9%
GOSS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add GOSS to Watchlist:       View:      Get Complete GOSS Trend Analysis ➞

Stock Chart of Mersana Therapeutics, Inc.MRSN Mersana Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 224.385 Millions
Recent Price: 7.32    
Market Intelligence Score: 40
Day Percent Change: 11.25%    
Day Change: 0.82
Week Change: 9.3%    
Year-to-date Change: -77.3%
MRSN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add MRSN to Watchlist:       View:      Get Complete MRSN Trend Analysis ➞

Stock Chart of Aligos Therapeutics, Inc.ALGS Aligos Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 76487 Millions
Recent Price: 10.55    
Market Intelligence Score: 70
Day Percent Change: 11.19%    
Day Change: 0.99
Week Change: 29.73%    
Year-to-date Change: -75.3%
ALGS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ALGS to Watchlist:       View:      Get Complete ALGS Trend Analysis ➞

Stock Chart of Quantum-Si incorporatedQSI Quantum-Si incorporated
Sector: Health Care
SubSector: Biotechnology
MarketCap: 256 Millions
Recent Price: 1.13    
Market Intelligence Score: 20
Day Percent Change: 11%    
Day Change: 0.11
Week Change: -0.89%    
Year-to-date Change: -58.9%
QSI Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add QSI to Watchlist:       View:      Get Complete QSI Trend Analysis ➞

Stock Chart of Atai Life Sciences N.V.ATAI Atai Life Sciences N.V.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 287 Millions
Recent Price: 4.58    
Market Intelligence Score: 80
Day Percent Change: 10.58%    
Day Change: 0.42
Week Change: 9.48%    
Year-to-date Change: 230.1%
ATAI Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ATAI to Watchlist:       View:      Get Complete ATAI Trend Analysis ➞

Stock Chart of Entrada Therapeutics, Inc.TRDA Entrada Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 481 Millions
Recent Price: 5.47    
Market Intelligence Score: 25
Day Percent Change: 10.55%    
Day Change: 0.56
Week Change: 11.81%    
Year-to-date Change: -66.1%
TRDA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add TRDA to Watchlist:       View:      Get Complete TRDA Trend Analysis ➞

Stock Chart of Apollomics, Inc.APLM Apollomics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 481 Millions
Recent Price: 3.93    
Market Intelligence Score: 68
Day Percent Change: 10%    
Day Change: 0.55
Week Change: 2.37%    
Year-to-date Change: -38.0%
APLM Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add APLM to Watchlist:       View:      Get Complete APLM Trend Analysis ➞

Stock Chart of Fortress Biotech, Inc.FBIO Fortress Biotech, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 116.885 Millions
Recent Price: 2.58    
Market Intelligence Score: 100
Day Percent Change: 9.27%    
Day Change: 0.19
Week Change: 14.29%    
Year-to-date Change: 10.3%
FBIO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add FBIO to Watchlist:       View:      Get Complete FBIO Trend Analysis ➞

Stock Chart of CASI Pharmaceuticals, Inc.CASI CASI Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 210.085 Millions
Recent Price: 2.31    
Market Intelligence Score: 80
Day Percent Change: 8.33%    
Day Change: 0.19
Week Change: 27.32%    
Year-to-date Change: -12.7%
CASI Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CASI to Watchlist:       View:      Get Complete CASI Trend Analysis ➞

Stock Chart of Anika Therapeutics, Inc.ANIK Anika Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 438.385 Millions
Recent Price: 9.38    
Market Intelligence Score: 70
Day Percent Change: 8.12%    
Day Change: 0.68
Week Change: 4.75%    
Year-to-date Change: -45.0%
ANIK Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ANIK to Watchlist:       View:      Get Complete ANIK Trend Analysis ➞

Stock Chart of Design Therapeutics, Inc.DSGN Design Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 367 Millions
Recent Price: 5.53    
Market Intelligence Score: 100
Day Percent Change: 7.52%    
Day Change: 0.36
Week Change: -0.19%    
Year-to-date Change: -16.5%
DSGN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add DSGN to Watchlist:       View:      Get Complete DSGN Trend Analysis ➞

Stock Chart of Terns Pharmaceuticals, Inc.TERN Terns Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 611 Millions
Recent Price: 6.96    
Market Intelligence Score: 80
Day Percent Change: 7.3%    
Day Change: 0.46
Week Change: -0.15%    
Year-to-date Change: 22.0%
TERN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add TERN to Watchlist:       View:      Get Complete TERN Trend Analysis ➞

Stock Chart of Omeros CorporationOMER Omeros Corporation
Sector: Health Care
SubSector: Biotechnology
MarketCap: 759.585 Millions
Recent Price: 4.16    
Market Intelligence Score: 30
Day Percent Change: 6.92%    
Day Change: 0.29
Week Change: 8.74%    
Year-to-date Change: -54.7%
OMER Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add OMER to Watchlist:       View:      Get Complete OMER Trend Analysis ➞

Stock Chart of Replimune Group, Inc.REPL Replimune Group, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 367.885 Millions
Recent Price: 5.40    
Market Intelligence Score: 20
Day Percent Change: 6.67%    
Day Change: 0.35
Week Change: 4.67%    
Year-to-date Change: -53.8%
REPL Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add REPL to Watchlist:       View:      Get Complete REPL Trend Analysis ➞

Stock Chart of Keros Therapeutics, Inc.KROS Keros Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 17887 Millions
Recent Price: 15.21    
Market Intelligence Score: 80
Day Percent Change: 6.61%    
Day Change: 0.94
Week Change: 5.2%    
Year-to-date Change: -4.2%
KROS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add KROS to Watchlist:       View:      Get Complete KROS Trend Analysis ➞

Stock Chart of NuCana plcNCNA NuCana plc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 185.785 Millions
Recent Price: 3.19    
Market Intelligence Score: 30
Day Percent Change: 6.43%    
Day Change: 0.2
Week Change: -20.24%    
Year-to-date Change: -98.6%
NCNA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add NCNA to Watchlist:       View:      Get Complete NCNA Trend Analysis ➞

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Performance: Year-to-date, Week and Day
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