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Best Biotech Stocks

Quick Read: Best Biotech Stocks List By Performances & Trends:
Daily, Weekly, Year-to-Date, Market Cap (Size) & Technical Trends
Best Biotech Stocks Views: Quick Browse View, Summary & Slide Show View

12Stocks.com Biotech Stocks Performances & Trends Daily
September 18, 2025 - All trends (long term, mid-term and short term) for Biotech sector looks good.

The overall market intelligence score is 80 (0-bearish to 100-bullish) which puts Biotech sector in short term neutral to bullish trend.

The market intelligence score from previous trading session is 60 and hence an improvement of trend.

 Year To Date Performance: 4.23268 %
 Weekly Performance: 1.58679 %
 Daily Performance: 1.72763 %
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Biotech Sector Trend
80 / 100
Here are the market intelligence trend scores of the most requested Biotech stocks at 12Stocks.com (click stock name for detailed review):

12Stocks.com: Investing in Biotech sector with Stocks
The following table helps investors and traders sort through current performance and trends (as measured by market intelligence score) of various stocks in the Biotech sector.

Quick View: Move mouse or cursor over stock symbol (ticker) to view short-term Technical chart and over stock name to view long term chart. Click on to add stock symbol to your watchlist and to view watchlist. Click on any ticker or stock name for detailed market intelligence report for that stock.

12Stocks.com Performance of Stocks in Biotech Sector

TickerStock NameWatchlistCategoryRecent PriceMarket Intelligence ScoreChange %YTD Change%
KLDOKaleido  Biotechnology0.01809,900.00NA
NLTXNeoleukin  Biotechnology15.1090332.670.00%
SYRSSyros  Biotechnology0.0270226.23-91.35%
ATNXAthenex  Biotechnology0.0150103.330.00%
APTOAptose  Biotechnology2.012017.54-71.55%
ALVRAlloVir  Biotechnology11.4710016.9210.82%
MNPRMonopar  Biotechnology66.6410016.91199.91%
CARACara  Biotechnology18.2510014.3413.49%
TYRATyra  Biotechnology12.157114.26-15.83%
ZURAZura Bio Biotechnology1.905113.71-20.40%
CRBPCorbus  Biotechnology11.6210013.15-3.49%
OCGNOcugen  Biotechnology1.3210012.8246.67%
SPRBSpruce  Biotechnology11.3910012.49-63.79%
TRDAEntrada  Biotechnology5.092510.55-66.05%
MEIPMEI Pharma Biotechnology3.073010.4320.39%
DBVTDBV Technologies Biotechnology9.84809.75202.77%
BHVNBiohaven  Biotechnology14.70708.97-60.57%
ATXIAvenue  Biotechnology0.58708.61-69.95%
ROIVRoivant  Biotechnology15.281007.7626.49%
PETXAratana  Biotechnology16.30607.380.00%
NVLNNovelion  Biotechnology16.30607.380.00%
XNCRXencor  Biotechnology9.251007.31-61.12%
ALECAlector  Biotechnology2.95906.8856.08%
ONCYOncolytics  Biotechnology1.351006.3045.19%
FREQFrequency  Biotechnology14.98805.940.00%
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Performance: Year-to-date, Week and Day
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Detailed Overview of Biotech Stocks
Biotech Technical Overview, Leaders & Laggards, Top Biotech ETF Funds & Detailed Biotech Stocks List, Charts, Trends & More

Biotech Sector: Technical Analysis, Trends & YTD Performance
Biotech sector, as represented by XBI, an exchange-traded fund [ETF] that holds basket of Biotech stocks (e.g, Amgen, Celgene) is up by 4.23268% and is currently underperforming the overall market by -9.35602% year-to-date. Below is a quick view of Technical charts and trends:

XBI Weekly Chart
Long Term Trend: Very Good
Medium Term Trend: Very Good

XBI Daily Chart
Short Term Trend: Very Good
Overall Trend Score: 80
YTD Performance: 4.23268%
**Trend Scores & Views Are Only For Educational Purposes And Not For Investing


12Stocks.com: Top Performing Biotech Sector Stocks
Hot Biotech Stocks of 2025 We try to spot trends by analyzing the performances of various stocks or components within Biotech sector and try to find best performing stocks. The movers and shakers. The winners and losers.

The top performing Biotech sector stocks year to date are
Celcuity [316%] I-Mab ADR[307%] Galectin [292%]
Immuneering Corp[265%] Nektar [254%] Precigen [254%]
Nanobiotix ADR[252%] Gossamer Bio[208%] DBV Technologies[203%]
Monopar [200%] ATAI Life[194%]
View complete list of Biotech stocks by year-to-date performance

Now, more recently, over last week, the top performing Biotech sector stocks on the move are
Athersys [193287%] VBI Vaccines[86898.5%] ContraFect [47677.8%]
Clovis Oncology[39610.5%] NanoString Technologies[17224.7%] Neptune Wellness[14100%]
Achillion [10033.3%] Nymox [8258.5%] Epizyme [5739.5%]
Portola [4717.6%] Strongbridge Biopharma[3417.5%]
View complete list of Biotech stocks by weekly performance

Unfortunately not all Biotech stocks have done well this year. Investors of these stocks hope they have seen the worst and hope that these stocks are set to bounce back. The bearish stocks in this index year to date (YTD) are
Vaxxinity [-100%] Petros [-100%] Translate Bio[-95%]
Palatin Technologies[-93%] Syros [-91%] Pliant [-89%]
Affimed N.V[-87%] Unity nology[-86%] Sarepta [-85%]
IGM [-80%] Rocket [-76%] Allakos [-73%]
.
Investors can get enhanced performance by riding the current stock trends. Using complex algorithms, 12Stocks.com has come up with market intelligence scores (on 0-bearish to 100-bullish scale) to identify best trending stocks. Top trending Biotech stocks are
AlloVir [100] Monopar [100] Cara [100]
Corbus [100] Ocugen [100] Spruce [100]
Roivant [100] Xencor [100] Oncolytics [100]
Tango [100] Arcus [100] RAPT [100]
View complete list of Biotech stocks by 12Stocks.com trends

12Stocks.com: Investing in Biotech Sector using Exchange Traded Funds
The following table shows list of key exchange traded funds (ETF) that help investors track Biotech Index. For detailed view, check out our ETF Funds section of our website.

Quick View: Move mouse or cursor over ETF symbol (ticker) to view short-term Technical chart and over ETF name to view long term chart. Click on ticker or stock name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist.

12Stocks.com List of ETFs that track Biotech Index

TickerETF NameWatchlistRecent PriceMarket Intelligence ScoreChange %Week %Year-to-date %
UBIOBiotechnology  73.3480-0.0681292260.7480%
HCRFEdge Multifactor 67.142309999NA
SICKHealthcare Bear 3X 37.903609999NA
LABSBiotech Bear 1X 24.185609999NA
BTECPrincipal Healthcare Innovators 39.493001.023280%
 Market Intelligence Score (0-Bearish to 100-Bullish)
12Stocks.com: Charts, Trends, Fundamental Data and Performances of Biotech Stocks
We now take in-depth look at all Biotech stocks including charts, multi-period performances and overall trends (as measured by market intelligence score).

One can sort Biotech stocks (click link to choose) by Daily, Weekly and by Year-to-Date performances. Also, one can sort by size of the company or by market capitalization.
Select Your Default Chart Type:
Long Term Chart Daily Chart Weekly Chart 
Long Term Chart (Default)
Weekly Chart Example
Daily Chart Example
Click on stock symbol or name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist. Quick View: Move mouse or cursor over "Daily" to quickly view daily Technical stock chart and over "Weekly" to view weekly Technical stock chart.

Stock Chart of Kaleido BioSciences, Inc.KLDO Kaleido BioSciences, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 229.185 Millions
Recent Price: 0.01    
Market Intelligence Score: 80
Day Percent Change: 9900%    
Day Change: -9999
Week Change: 9900%    
Year-to-date Change: 9,900.0%
KLDO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add KLDO to Watchlist:       View:      Get Complete KLDO Trend Analysis ➞

Stock Chart of Neoleukin Therapeutics, Inc.NLTX Neoleukin Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 412.685 Millions
Recent Price: 15.10    
Market Intelligence Score: 90
Day Percent Change: 332.665%    
Day Change: -9999
Week Change: 7.85714%    
Year-to-date Change: 0.0%
NLTX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add NLTX to Watchlist:       View:      Get Complete NLTX Trend Analysis ➞

Stock Chart of Syros Pharmaceuticals, Inc.SYRS Syros Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 275.485 Millions
Recent Price: 0.02    
Market Intelligence Score: 70
Day Percent Change: 226.23%    
Day Change: -9999
Week Change: 1709.09%    
Year-to-date Change: -91.4%
SYRS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add SYRS to Watchlist:       View:      Get Complete SYRS Trend Analysis ➞

Stock Chart of Athenex, Inc.ATNX Athenex, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 631.785 Millions
Recent Price: 0.01    
Market Intelligence Score: 50
Day Percent Change: 103.333%    
Day Change: -9999
Week Change: -95.6429%    
Year-to-date Change: 0.0%
ATNX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ATNX to Watchlist:       View:      Get Complete ATNX Trend Analysis ➞

Stock Chart of Aptose Biosciences Inc.APTO Aptose Biosciences Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 484.585 Millions
Recent Price: 2.01    
Market Intelligence Score: 20
Day Percent Change: 17.5439%    
Day Change: -9999
Week Change: -42.2414%    
Year-to-date Change: -71.5%
APTO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add APTO to Watchlist:       View:      Get Complete APTO Trend Analysis ➞

Stock Chart of AlloVir, Inc.ALVR AlloVir, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 25787 Millions
Recent Price: 11.47    
Market Intelligence Score: 100
Day Percent Change: 16.9215%    
Day Change: -9999
Week Change: 20.8641%    
Year-to-date Change: 10.8%
ALVR Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ALVR to Watchlist:       View:      Get Complete ALVR Trend Analysis ➞

Stock Chart of Monopar Therapeutics IncMNPR Monopar Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 272.77 Millions
Recent Price: 66.64    
Market Intelligence Score: 100
Day Percent Change: 16.9123%    
Day Change: -1.16
Week Change: 48.3196%    
Year-to-date Change: 199.9%
MNPR Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add MNPR to Watchlist:       View:      Get Complete MNPR Trend Analysis ➞

Stock Chart of Cara Therapeutics, Inc.CARA Cara Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 597.985 Millions
Recent Price: 18.25    
Market Intelligence Score: 100
Day Percent Change: 14.3396%    
Day Change: -9999
Week Change: 25.4199%    
Year-to-date Change: 13.5%
CARA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CARA to Watchlist:       View:      Get Complete CARA Trend Analysis ➞

Stock Chart of Tyra Biosciences IncTYRA Tyra Biosciences Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 674.21 Millions
Recent Price: 12.15    
Market Intelligence Score: 71
Day Percent Change: 14.26%    
Day Change: 1.46
Week Change: 9.35%    
Year-to-date Change: -15.8%
TYRA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add TYRA to Watchlist:       View:      Get Complete TYRA Trend Analysis ➞

Stock Chart of Zura Bio LtdZURA Zura Bio Ltd
Sector: Health Care
SubSector: Biotechnology
MarketCap: 143.04 Millions
Recent Price: 1.90    
Market Intelligence Score: 51
Day Percent Change: 13.71%    
Day Change: 0.24
Week Change: 15.7%    
Year-to-date Change: -20.4%
ZURA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ZURA to Watchlist:       View:      Get Complete ZURA Trend Analysis ➞

Stock Chart of Corbus Pharmaceuticals Holdings IncCRBP Corbus Pharmaceuticals Holdings Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 120.84 Millions
Recent Price: 11.62    
Market Intelligence Score: 100
Day Percent Change: 13.1451%    
Day Change: 0.48
Week Change: 21.9307%    
Year-to-date Change: -3.5%
CRBP Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CRBP to Watchlist:       View:      Get Complete CRBP Trend Analysis ➞

Stock Chart of Ocugen IncOCGN Ocugen Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 321.67 Millions
Recent Price: 1.32    
Market Intelligence Score: 100
Day Percent Change: 12.8205%    
Day Change: 0
Week Change: 28.1553%    
Year-to-date Change: 46.7%
OCGN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add OCGN to Watchlist:       View:      Get Complete OCGN Trend Analysis ➞

Stock Chart of Spruce Biosciences, Inc.SPRB Spruce Biosciences, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 49487 Millions
Recent Price: 11.39    
Market Intelligence Score: 100
Day Percent Change: 12.4938%    
Day Change: -9999
Week Change: 39.3272%    
Year-to-date Change: -63.8%
SPRB Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add SPRB to Watchlist:       View:      Get Complete SPRB Trend Analysis ➞

Stock Chart of Entrada Therapeutics IncTRDA Entrada Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 201.22 Millions
Recent Price: 5.09    
Market Intelligence Score: 25
Day Percent Change: 10.55%    
Day Change: 0.56
Week Change: 11.81%    
Year-to-date Change: -66.1%
TRDA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add TRDA to Watchlist:       View:      Get Complete TRDA Trend Analysis ➞

Stock Chart of MEI Pharma IncMEIP MEI Pharma Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 138.9 Millions
Recent Price: 3.07    
Market Intelligence Score: 30
Day Percent Change: 10.4317%    
Day Change: 0.03
Week Change: -36.701%    
Year-to-date Change: 20.4%
MEIP Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add MEIP to Watchlist:       View:      Get Complete MEIP Trend Analysis ➞

Stock Chart of DBV Technologies ADRDBVT DBV Technologies ADR
Sector: Health Care
SubSector: Biotechnology
MarketCap: 245.22 Millions
Recent Price: 9.84    
Market Intelligence Score: 80
Day Percent Change: 9.74794%    
Day Change: -0.26
Week Change: 0.510725%    
Year-to-date Change: 202.8%
DBVT Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add DBVT to Watchlist:       View:      Get Complete DBVT Trend Analysis ➞

Stock Chart of Biohaven LtdBHVN Biohaven Ltd
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1678.9 Millions
Recent Price: 14.70    
Market Intelligence Score: 70
Day Percent Change: 8.96961%    
Day Change: -0.02
Week Change: 1.51934%    
Year-to-date Change: -60.6%
BHVN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add BHVN to Watchlist:       View:      Get Complete BHVN Trend Analysis ➞

Stock Chart of Avenue Therapeutics, Inc.ATXI Avenue Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 118.185 Millions
Recent Price: 0.58    
Market Intelligence Score: 70
Day Percent Change: 8.61423%    
Day Change: -9999
Week Change: 23.9846%    
Year-to-date Change: -69.9%
ATXI Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ATXI to Watchlist:       View:      Get Complete ATXI Trend Analysis ➞

Stock Chart of Roivant Sciences LtdROIV Roivant Sciences Ltd
Sector: Health Care
SubSector: Biotechnology
MarketCap: 8822.83 Millions
Recent Price: 15.28    
Market Intelligence Score: 100
Day Percent Change: 7.7574%    
Day Change: 0.09
Week Change: 13.3531%    
Year-to-date Change: 26.5%
ROIV Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ROIV to Watchlist:       View:      Get Complete ROIV Trend Analysis ➞

Stock Chart of Aratana Therapeutics, Inc.PETX Aratana Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 199.25 Millions
Recent Price: 16.30    
Market Intelligence Score: 60
Day Percent Change: 7.37813%    
Day Change: -9999
Week Change: 579.167%    
Year-to-date Change: 0.0%
PETX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PETX to Watchlist:       View:      Get Complete PETX Trend Analysis ➞

Stock Chart of Novelion Therapeutics Inc.NVLN Novelion Therapeutics Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 198.02 Millions
Recent Price: 16.30    
Market Intelligence Score: 60
Day Percent Change: 7.37813%    
Day Change: -9999
Week Change: 579.167%    
Year-to-date Change: 0.0%
NVLN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add NVLN to Watchlist:       View:      Get Complete NVLN Trend Analysis ➞

Stock Chart of Xencor IncXNCR Xencor Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 609.81 Millions
Recent Price: 9.25    
Market Intelligence Score: 100
Day Percent Change: 7.30858%    
Day Change: -0.07
Week Change: 11.3117%    
Year-to-date Change: -61.1%
XNCR Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add XNCR to Watchlist:       View:      Get Complete XNCR Trend Analysis ➞

Stock Chart of Alector IncALEC Alector Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 304.65 Millions
Recent Price: 2.95    
Market Intelligence Score: 90
Day Percent Change: 6.88406%    
Day Change: 0.07
Week Change: 5.35714%    
Year-to-date Change: 56.1%
ALEC Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ALEC to Watchlist:       View:      Get Complete ALEC Trend Analysis ➞

Stock Chart of Oncolytics Biotech, IncONCY Oncolytics Biotech, Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 107.32 Millions
Recent Price: 1.35    
Market Intelligence Score: 100
Day Percent Change: 6.29921%    
Day Change: 0
Week Change: -2.8777%    
Year-to-date Change: 45.2%
ONCY Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ONCY to Watchlist:       View:      Get Complete ONCY Trend Analysis ➞

Stock Chart of Frequency Therapeutics, Inc.FREQ Frequency Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 676.085 Millions
Recent Price: 14.98    
Market Intelligence Score: 80
Day Percent Change: 5.94059%    
Day Change: -9999
Week Change: 26.6272%    
Year-to-date Change: 0.0%
FREQ Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add FREQ to Watchlist:       View:      Get Complete FREQ Trend Analysis ➞

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Click To Change The Sort Order: By Market Cap or Company Size
Performance: Year-to-date, Week and Day
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