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Best Biotech Stocks

Quick Read: Best Biotech Stocks List By Performances & Trends:
Daily, Weekly, Year-to-Date, Market Cap (Size) & Technical Trends
Best Biotech Stocks Views: Quick Browse View, Summary & Slide Show View

12Stocks.com Biotech Stocks Performances & Trends Daily
August 29, 2025 - All trends (long term, mid-term and short term) for Biotech sector looks good.

The overall market intelligence score is 100 (0-bearish to 100-bullish) which puts Biotech sector in short term bullish trend.

The market intelligence score from previous trading session is 90 and hence an improvement of trend.

 Year To Date Performance: -3.34 %
 Weekly Performance: -1.5 %
 Daily Performance: -0.81 %
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Biotech Sector Trend
100 / 100
Here are the market intelligence trend scores of the most requested Biotech stocks at 12Stocks.com (click stock name for detailed review):

12Stocks.com: Investing in Biotech sector with Stocks
The following table helps investors and traders sort through current performance and trends (as measured by market intelligence score) of various stocks in the Biotech sector.

Quick View: Move mouse or cursor over stock symbol (ticker) to view short-term Technical chart and over stock name to view long term chart. Click on to add stock symbol to your watchlist and to view watchlist. Click on any ticker or stock name for detailed market intelligence report for that stock.

12Stocks.com Performance of Stocks in Biotech Sector

TickerStock NameWatchlistCategoryRecent PriceMarket Intelligence ScoreChange %YTD Change%
PCVXVaxcyte  Biotechnology30.55402.08%-61.02%
RPTXRepare  Biotechnology1.65900.98%18.32%
ALNYAlnylam  Biotechnology454.18802.02%98.70%
PASGPassage Bio Biotechnology7.0430-3.77%-34.75%
ARQTArcutis Bio Biotechnology15.65600.00%13.35%
ORICORIC  Biotechnology10.26801.89%20.07%
BDTXBlack Diamond Biotechnology2.87604.23%26.64%
CCCCC4  Biotechnology2.58600.38%-27.50%
IMNMImmunome  Biotechnology9.95303.97%-6.31%
LYRALyra  Biotechnology7.03601.24%-28.74%
GMABGenmab A/S Biotechnology24.781001.50%17.01%
RNAAvidity  Biotechnology47.821000.72%53.58%
BNTXBioNTech SE Biotechnology103.0120-0.48%-2.79%
LTRNLantern Pharma Biotechnology4.0520-6.26%31.35%
MRNAModerna  Biotechnology24.0310-1.80%-39.04%
ITOSiTeos  Biotechnology10.1370-0.10%32.81%
GLPGGalapagos NV Biotechnology32.91700.50%16.07%
NBIXNeurocrine  Biotechnology138.131001.54%-0.89%
ROIVRoivant  Biotechnology11.99900.77%-0.17%
SRPTSarepta  Biotechnology18.0730-2.53%-83.50%
TECHBio-Techne  Biotechnology54.86500.98%-25.20%
IONSIonis  Biotechnology42.75600.99%23.67%
JAZZJazz  Biotechnology124.431001.23%-2.13%
ASNDAscendis Pharma Biotechnology193.01600.00%40.05%
ACADACADIA  Biotechnology26.57100-0.62%35.07%
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Performance: Year-to-date, Week and Day
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Detailed Overview of Biotech Stocks
Biotech Technical Overview, Leaders & Laggards, Top Biotech ETF Funds & Detailed Biotech Stocks List, Charts, Trends & More

Biotech Sector: Technical Analysis, Trends & YTD Performance
Biotech sector, as represented by XBI, an exchange-traded fund [ETF] that holds basket of Biotech stocks (e.g, Amgen, Celgene) is down by -3.34% and is currently underperforming the overall market by -10.57% year-to-date. Below is a quick view of Technical charts and trends:

XBI Weekly Chart
Long Term Trend: Very Good
Medium Term Trend: Good

XBI Daily Chart
Short Term Trend: Very Good
Overall Trend Score: 100
YTD Performance: -3.34%
**Trend Scores & Views Are Only For Educational Purposes And Not For Investing


12Stocks.com: Top Performing Biotech Sector Stocks
Hot Biotech Stocks of 2025 We try to spot trends by analyzing the performances of various stocks or components within Biotech sector and try to find best performing stocks. The movers and shakers. The winners and losers.

The top performing Biotech sector stocks year to date are
I Mab[454%] Matinas BioPharma[241%] Nanobiotix S.A[239%]
Atai Life[230%] Precigen [225%] DBV Technologies[209%]
Galectin [201%] Sol-Gel Technologies[177%] Rigel [150%]
Gossamer Bio[140%] Lineage Cell[133%] Tango [127%]
View complete list of Biotech stocks by year-to-date performance

Now, more recently, over last week, the top performing Biotech sector stocks on the move are
Precigen [96.8%] Sol-Gel Technologies[69.2%] ALX Oncology[57.3%]
Immuneering [52.3%] Minerva Neuro[34.5%] Aligos [29.7%]
Karyopharm [29.5%] CASI [27.3%] Zentalis [26.4%]
Rocket [23.1%] Tenaya [22.5%] Nanobiotix S.A[18.8%]
View complete list of Biotech stocks by weekly performance

Unfortunately not all Biotech stocks have done well this year. Investors of these stocks hope they have seen the worst and hope that these stocks are set to bounce back. The bearish stocks in this index year to date (YTD) are
NuCana [-99%] ADiTx [-98%] Adaptimmune [-89%]
Pliant [-89%] X4 [-86%] Sarepta [-84%]
Mustang Bio[-81%] RedHill Biopharma[-79%] Acrivon [-78%]
Mersana [-77%] Aligos [-75%] Rocket [-70%]
.
Investors can get enhanced performance by riding the current stock trends. Using complex algorithms, 12Stocks.com has come up with market intelligence scores (on 0-bearish to 100-bullish scale) to identify best trending stocks. Top trending Biotech stocks are
ALX Oncology[100] Precigen [100] Aligos [100]
Design [100] Keros [100] Coherus [100]
Kura Oncology[100] Denali [100] Prelude [100]
FibroGen [100] Madrigal [100] Arcus [100]
View complete list of Biotech stocks by 12Stocks.com trends

12Stocks.com: Investing in Biotech Sector using Exchange Traded Funds
The following table shows list of key exchange traded funds (ETF) that help investors track Biotech Index. For detailed view, check out our ETF Funds section of our website.

Quick View: Move mouse or cursor over ETF symbol (ticker) to view short-term Technical chart and over ETF name to view long term chart. Click on ticker or stock name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist.

12Stocks.com List of ETFs that track Biotech Index

TickerETF NameWatchlistRecent PriceMarket Intelligence ScoreChange %Week %Year-to-date %
LABDBiotech Bear 3X 5.6620-2.55-1.37-19.84%
XBIBiotech  89.56100-0.81-1.5-3.34%
IBBBiotechnology  138.59800.730.730.89%
LABUBiotech Bull 3X 70.311002.380.61-22.08%
IYHHealthcare  57.7660-0.312.14-0.44%
ZBIOShort Biotech 16.71603.741.01106.72%
IXJGlobal Healthcare  87.55600.821.4-2.62%
CUREHealthcare Bull 3X 80.0050-1.026.93-12.21%
IHFHealthcare Providers  47.05400.90.04-10.59%
BBCBio Biotechnology Clinical 22.93902.050.29-5.46%
FBTFirst NYSE 172.0780-0.150.664.14%
PBEBiotech & Genome 68.46800.311.642.9%
BIBBiotechnology  55.82601.032.4711.53%
PTHDWA Healthcare Momentum 40.06800.670.47-1.58%
BBHBiotech  165.39600.610.531.51%
BISShort Biotech 14.2740-0.99-2.37-20.83%
BBPBio Biotechnology Products 67.71900.761.0512.25%
 Market Intelligence Score (0-Bearish to 100-Bullish)
12Stocks.com: Charts, Trends, Fundamental Data and Performances of Biotech Stocks
We now take in-depth look at all Biotech stocks including charts, multi-period performances and overall trends (as measured by market intelligence score).

One can sort Biotech stocks (click link to choose) by Daily, Weekly and by Year-to-Date performances. Also, one can sort by size of the company or by market capitalization.
Select Your Default Chart Type:
Long Term Chart Daily Chart Weekly Chart 
Long Term Chart (Default)
Weekly Chart Example
Daily Chart Example
Click on stock symbol or name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist. Quick View: Move mouse or cursor over "Daily" to quickly view daily Technical stock chart and over "Weekly" to view weekly Technical stock chart.

Stock Chart of Vaxcyte, Inc.PCVX Vaxcyte, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 13887 Millions
Recent Price: 30.55    
Market Intelligence Score: 40
Day Percent Change: 2.08%    
Day Change: 0.65
Week Change: 1.53%    
Year-to-date Change: -61.0%
PCVX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PCVX to Watchlist:       View:      Get Complete PCVX Trend Analysis ➞

Stock Chart of Repare Therapeutics Inc.RPTX Repare Therapeutics Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 13687 Millions
Recent Price: 1.65    
Market Intelligence Score: 90
Day Percent Change: 0.98%    
Day Change: 0.01
Week Change: -0.64%    
Year-to-date Change: 18.3%
RPTX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add RPTX to Watchlist:       View:      Get Complete RPTX Trend Analysis ➞

Stock Chart of Alnylam Pharmaceuticals, Inc.ALNY Alnylam Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 12793.2 Millions
Recent Price: 454.18    
Market Intelligence Score: 80
Day Percent Change: 2.02%    
Day Change: 9.24
Week Change: 5.61%    
Year-to-date Change: 98.7%
ALNY Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ALNY to Watchlist:       View:      Get Complete ALNY Trend Analysis ➞

Stock Chart of Passage Bio, Inc.PASG Passage Bio, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 12787 Millions
Recent Price: 7.04    
Market Intelligence Score: 30
Day Percent Change: -3.77%    
Day Change: -0.29
Week Change: -2.5%    
Year-to-date Change: -34.8%
PASG Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PASG to Watchlist:       View:      Get Complete PASG Trend Analysis ➞

Stock Chart of Arcutis Biotherapeutics, Inc.ARQT Arcutis Biotherapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 12787 Millions
Recent Price: 15.65    
Market Intelligence Score: 60
Day Percent Change: 0%    
Day Change: 0
Week Change: -1.19%    
Year-to-date Change: 13.4%
ARQT Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ARQT to Watchlist:       View:      Get Complete ARQT Trend Analysis ➞

Stock Chart of ORIC Pharmaceuticals, Inc.ORIC ORIC Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 12787 Millions
Recent Price: 10.26    
Market Intelligence Score: 80
Day Percent Change: 1.89%    
Day Change: 0.18
Week Change: -2.42%    
Year-to-date Change: 20.1%
ORIC Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ORIC to Watchlist:       View:      Get Complete ORIC Trend Analysis ➞

Stock Chart of Black Diamond Therapeutics, Inc.BDTX Black Diamond Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 12587 Millions
Recent Price: 2.87    
Market Intelligence Score: 60
Day Percent Change: 4.23%    
Day Change: 0.11
Week Change: -2.87%    
Year-to-date Change: 26.6%
BDTX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add BDTX to Watchlist:       View:      Get Complete BDTX Trend Analysis ➞

Stock Chart of C4 Therapeutics, Inc.CCCC C4 Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 12587 Millions
Recent Price: 2.58    
Market Intelligence Score: 60
Day Percent Change: 0.38%    
Day Change: 0.01
Week Change: 11.06%    
Year-to-date Change: -27.5%
CCCC Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CCCC to Watchlist:       View:      Get Complete CCCC Trend Analysis ➞

Stock Chart of Immunome, Inc.IMNM Immunome, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 12487 Millions
Recent Price: 9.95    
Market Intelligence Score: 30
Day Percent Change: 3.97%    
Day Change: 0.38
Week Change: 0.1%    
Year-to-date Change: -6.3%
IMNM Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add IMNM to Watchlist:       View:      Get Complete IMNM Trend Analysis ➞

Stock Chart of Lyra Therapeutics, Inc.LYRA Lyra Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 12487 Millions
Recent Price: 7.03    
Market Intelligence Score: 60
Day Percent Change: 1.24%    
Day Change: 0.09
Week Change: 3.38%    
Year-to-date Change: -28.7%
LYRA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add LYRA to Watchlist:       View:      Get Complete LYRA Trend Analysis ➞

Stock Chart of Genmab A/SGMAB Genmab A/S
Sector: Health Care
SubSector: Biotechnology
MarketCap: 12482.3 Millions
Recent Price: 24.78    
Market Intelligence Score: 100
Day Percent Change: 1.5%    
Day Change: 0.36
Week Change: 6.27%    
Year-to-date Change: 17.0%
GMAB Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add GMAB to Watchlist:       View:      Get Complete GMAB Trend Analysis ➞

Stock Chart of Avidity Biosciences, Inc.RNA Avidity Biosciences, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 12287 Millions
Recent Price: 47.82    
Market Intelligence Score: 100
Day Percent Change: 0.72%    
Day Change: 0.32
Week Change: -3.06%    
Year-to-date Change: 53.6%
RNA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add RNA to Watchlist:       View:      Get Complete RNA Trend Analysis ➞

Stock Chart of BioNTech SEBNTX BioNTech SE
Sector: Health Care
SubSector: Biotechnology
MarketCap: 11933.7 Millions
Recent Price: 103.01    
Market Intelligence Score: 20
Day Percent Change: -0.48%    
Day Change: -0.53
Week Change: -1.71%    
Year-to-date Change: -2.8%
BNTX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add BNTX to Watchlist:       View:      Get Complete BNTX Trend Analysis ➞

Stock Chart of Lantern Pharma Inc.LTRN Lantern Pharma Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 11487 Millions
Recent Price: 4.05    
Market Intelligence Score: 20
Day Percent Change: -6.26%    
Day Change: -0.28
Week Change: -8.32%    
Year-to-date Change: 31.4%
LTRN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add LTRN to Watchlist:       View:      Get Complete LTRN Trend Analysis ➞

Stock Chart of Moderna, Inc.MRNA Moderna, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 11006.4 Millions
Recent Price: 24.03    
Market Intelligence Score: 10
Day Percent Change: -1.8%    
Day Change: -0.44
Week Change: -11.39%    
Year-to-date Change: -39.0%
MRNA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add MRNA to Watchlist:       View:      Get Complete MRNA Trend Analysis ➞

Stock Chart of iTeos Therapeutics, Inc.ITOS iTeos Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 10487 Millions
Recent Price: 10.13    
Market Intelligence Score: 70
Day Percent Change: -0.1%    
Day Change: -0.01
Week Change: 0.89%    
Year-to-date Change: 32.8%
ITOS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ITOS to Watchlist:       View:      Get Complete ITOS Trend Analysis ➞

Stock Chart of Galapagos NVGLPG Galapagos NV
Sector: Health Care
SubSector: Biotechnology
MarketCap: 9541.55 Millions
Recent Price: 32.91    
Market Intelligence Score: 70
Day Percent Change: 0.5%    
Day Change: 0.16
Week Change: 0.41%    
Year-to-date Change: 16.1%
GLPG Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add GLPG to Watchlist:       View:      Get Complete GLPG Trend Analysis ➞

Stock Chart of Neurocrine Biosciences, Inc.NBIX Neurocrine Biosciences, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 7897.85 Millions
Recent Price: 138.13    
Market Intelligence Score: 100
Day Percent Change: 1.54%    
Day Change: 2.05
Week Change: 3.02%    
Year-to-date Change: -0.9%
NBIX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add NBIX to Watchlist:       View:      Get Complete NBIX Trend Analysis ➞

Stock Chart of Roivant Sciences Ltd.ROIV Roivant Sciences Ltd.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 7780 Millions
Recent Price: 11.99    
Market Intelligence Score: 90
Day Percent Change: 0.77%    
Day Change: 0.09
Week Change: 0.51%    
Year-to-date Change: -0.2%
ROIV Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ROIV to Watchlist:       View:      Get Complete ROIV Trend Analysis ➞

Stock Chart of Sarepta Therapeutics, Inc.SRPT Sarepta Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 7388.05 Millions
Recent Price: 18.07    
Market Intelligence Score: 30
Day Percent Change: -2.53%    
Day Change: -0.52
Week Change: -1.18%    
Year-to-date Change: -83.5%
SRPT Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add SRPT to Watchlist:       View:      Get Complete SRPT Trend Analysis ➞

Stock Chart of Bio-Techne CorporationTECH Bio-Techne Corporation
Sector: Health Care
SubSector: Biotechnology
MarketCap: 6958.05 Millions
Recent Price: 54.86    
Market Intelligence Score: 50
Day Percent Change: 0.98%    
Day Change: 0.53
Week Change: -3.91%    
Year-to-date Change: -25.2%
TECH Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add TECH to Watchlist:       View:      Get Complete TECH Trend Analysis ➞

Stock Chart of Ionis Pharmaceuticals, Inc.IONS Ionis Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 6725.05 Millions
Recent Price: 42.75    
Market Intelligence Score: 60
Day Percent Change: 0.99%    
Day Change: 0.43
Week Change: 0.9%    
Year-to-date Change: 23.7%
IONS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add IONS to Watchlist:       View:      Get Complete IONS Trend Analysis ➞

Stock Chart of Jazz Pharmaceuticals plcJAZZ Jazz Pharmaceuticals plc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 5576.05 Millions
Recent Price: 124.43    
Market Intelligence Score: 100
Day Percent Change: 1.23%    
Day Change: 1.46
Week Change: 3.31%    
Year-to-date Change: -2.1%
JAZZ Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add JAZZ to Watchlist:       View:      Get Complete JAZZ Trend Analysis ➞

Stock Chart of Ascendis Pharma A/SASND Ascendis Pharma A/S
Sector: Health Care
SubSector: Biotechnology
MarketCap: 5470.35 Millions
Recent Price: 193.01    
Market Intelligence Score: 60
Day Percent Change: 0%    
Day Change: 0
Week Change: 0.4%    
Year-to-date Change: 40.1%
ASND Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ASND to Watchlist:       View:      Get Complete ASND Trend Analysis ➞

Stock Chart of ACADIA Pharmaceuticals Inc.ACAD ACADIA Pharmaceuticals Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 5400.35 Millions
Recent Price: 26.57    
Market Intelligence Score: 100
Day Percent Change: -0.62%    
Day Change: -0.16
Week Change: 1.04%    
Year-to-date Change: 35.1%
ACAD Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ACAD to Watchlist:       View:      Get Complete ACAD Trend Analysis ➞

To view more stocks, click on Next / Previous arrows or select different range:
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Performance: Year-to-date, Week and Day
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