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Best Biotech Stocks

Quick Read: Best Biotech Stocks List By Performances & Trends:
Daily, Weekly, Year-to-Date, Market Cap (Size) & Technical Trends
Best Biotech Stocks Views: Quick Browse View, Summary & Slide Show View

12Stocks.com Biotech Stocks Performances & Trends Daily
October 3, 2025 - All trends (long term, mid-term and short term) for Biotech sector looks good.

The overall market intelligence score is 100 (0-bearish to 100-bullish) which puts Biotech sector in short term bullish trend.

The market intelligence score from previous trading session is 90 and an improvement of trend continues.

 Year To Date Performance: 12.1001 %
 Weekly Performance: 5.2853 %
 Daily Performance: 1.18355 %
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Biotech Sector Trend
100 / 100
Here are the market intelligence trend scores of the most requested Biotech stocks at 12Stocks.com (click stock name for detailed review):

12Stocks.com: Investing in Biotech sector with Stocks
The following table helps investors and traders sort through current performance and trends (as measured by market intelligence score) of various stocks in the Biotech sector.

Quick View: Move mouse or cursor over stock symbol (ticker) to view short-term Technical chart and over stock name to view long term chart. Click on to add stock symbol to your watchlist and to view watchlist. Click on any ticker or stock name for detailed market intelligence report for that stock.

12Stocks.com Performance of Stocks in Biotech Sector

TickerStock NameWatchlistCategoryRecent PriceMarket Intelligence ScoreChange %YTD Change%
PROKProKidney Corp Biotechnology2.78806.92%60.69%
FREQFrequency  Biotechnology14.98805.94%0.00%
IKNAIkena Oncology Biotechnology17.16804.38%-13.33%
OBIOOrchestra BioMed Biotechnology2.66804.31%-50.56%
SGMOSangamo  Biotechnology0.70803.77%-38.05%
BMEABiomea Fusion Biotechnology2.09803.47%-43.36%
ANNXAnnexon  Biotechnology3.12802.97%-43.27%
TRILTrillium  Biotechnology56.00802.88%0.00%
CHRSCoherus Oncology Biotechnology1.66802.47%18.57%
MORMorphoSys AG Biotechnology18.96802.43%0.00%
TARSTarsus  Biotechnology58.72802.41%6.47%
MNKDMannkind Corp Biotechnology5.50802.23%-16.67%
CLLSCellectis ADR Biotechnology3.36802.13%85.64%
ACHNAchillion  Biotechnology22.80801.92%0.00%
VKTXViking  Biotechnology27.88801.86%-32.20%
LCTXLineage Cell Biotechnology1.72801.78%233.98%
ALDXAldeyra  Biotechnology5.32801.53%1.92%
IFRXInflaRx N.V Biotechnology1.38801.47%-44.80%
MGTXMeiraGTx  Biotechnology8.39801.45%33.81%
BMRNBiomarin  Biotechnology55.57801.29%-16.42%
CASCCascadian  Biotechnology18.22801.28%0.00%
AXSMAxsome  Biotechnology119.94801.16%37.36%
VRTXVertex  Biotechnology408.85801.15%0.76%
BNTXBioNTech SE Biotechnology103.44800.88%-10.29%
ATHXAthersys  Biotechnology11.99800.84%0.00%
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Performance: Year-to-date, Week and Day
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Detailed Overview of Biotech Stocks
Biotech Technical Overview, Leaders & Laggards, Top Biotech ETF Funds & Detailed Biotech Stocks List, Charts, Trends & More

Biotech Sector: Technical Analysis, Trends & YTD Performance
Biotech sector, as represented by XBI, an exchange-traded fund [ETF] that holds basket of Biotech stocks (e.g, Amgen, Celgene) is up by 12.1001% and is currently underperforming the overall market by -2.6578% year-to-date. Below is a quick view of Technical charts and trends:

XBI Weekly Chart
Long Term Trend: Very Good
Medium Term Trend: Very Good

XBI Daily Chart
Short Term Trend: Very Good
Overall Trend Score: 100
YTD Performance: 12.1001%
**Trend Scores & Views Are Only For Educational Purposes And Not For Investing


12Stocks.com: Top Performing Biotech Sector Stocks
Hot Biotech Stocks of 2025 We try to spot trends by analyzing the performances of various stocks or components within Biotech sector and try to find best performing stocks. The movers and shakers. The winners and losers.

The top performing Biotech sector stocks year to date are
Vor Biopharma[3175%] Nanobiotix ADR[581%] I-Mab ADR[358%]
Monopar [337%] Nektar [320%] DBV Technologies[277%]
Celcuity [276%] Galectin [263%] Cidara [261%]
Lineage Cell[234%] ATAI Life[221%]
View complete list of Biotech stocks by year-to-date performance

Now, more recently, over last week, the top performing Biotech sector stocks on the move are
Athersys [193287%] VBI Vaccines[86898.5%] ContraFect [47677.8%]
Clovis Oncology[39610.5%] NanoString Technologies[17224.7%] Neptune Wellness[14100%]
Achillion [10033.3%] Nymox [8258.5%] Epizyme [5739.5%]
Portola [4717.6%] Strongbridge Biopharma[3417.5%]
View complete list of Biotech stocks by weekly performance

Unfortunately not all Biotech stocks have done well this year. Investors of these stocks hope they have seen the worst and hope that these stocks are set to bounce back. The bearish stocks in this index year to date (YTD) are
Vaxxinity [-100%] Petros [-100%] Translate Bio[-95%]
Palatin Technologies[-93%] Syros [-91%] Pliant [-89%]
Affimed N.V[-87%] MoonLake Immuno[-86%] Unity nology[-86%]
Sarepta [-82%] Kala Bio[-80%] IGM [-80%]
.
Investors can get enhanced performance by riding the current stock trends. Using complex algorithms, 12Stocks.com has come up with market intelligence scores (on 0-bearish to 100-bullish scale) to identify best trending stocks. Top trending Biotech stocks are
Taysha Gene[100] DBV Technologies[100] Valneva SE[100]
Prime Medicine[100] AlloVir [100] Sarepta [100]
Monopar [100] Cara [100] Absci Corp[100]
Spruce [100] Cabaletta Bio[100] Compugen [100]
View complete list of Biotech stocks by 12Stocks.com trends

12Stocks.com: Investing in Biotech Sector using Exchange Traded Funds
The following table shows list of key exchange traded funds (ETF) that help investors track Biotech Index. For detailed view, check out our ETF Funds section of our website.

Quick View: Move mouse or cursor over ETF symbol (ticker) to view short-term Technical chart and over ETF name to view long term chart. Click on ticker or stock name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist.

12Stocks.com List of ETFs that track Biotech Index

TickerETF NameWatchlistRecent PriceMarket Intelligence ScoreChange %Week %Year-to-date %
UBIOBiotechnology  73.3480-0.0681292260.7480%
HCRFEdge Multifactor 67.142309999NA
SICKHealthcare Bear 3X 37.903609999NA
LABSBiotech Bear 1X 24.185609999NA
BTECPrincipal Healthcare Innovators 39.493001.023280%
 Market Intelligence Score (0-Bearish to 100-Bullish)
12Stocks.com: Charts, Trends, Fundamental Data and Performances of Biotech Stocks
We now take in-depth look at all Biotech stocks including charts, multi-period performances and overall trends (as measured by market intelligence score).

One can sort Biotech stocks (click link to choose) by Daily, Weekly and by Year-to-Date performances. Also, one can sort by size of the company or by market capitalization.
Select Your Default Chart Type:
Long Term Chart Daily Chart Weekly Chart 
Long Term Chart (Default)
Weekly Chart Example
Daily Chart Example
Click on stock symbol or name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist. Quick View: Move mouse or cursor over "Daily" to quickly view daily Technical stock chart and over "Weekly" to view weekly Technical stock chart.

Stock Chart of ProKidney CorpPROK ProKidney Corp
Sector: Health Care
SubSector: Biotechnology
MarketCap: 662.14 Millions
Recent Price: 2.78    
Market Intelligence Score: 80
Day Percent Change: 6.92308%    
Day Change: 0.04
Week Change: 2.20588%    
Year-to-date Change: 60.7%
PROK Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PROK to Watchlist:       View:      Get Complete PROK Trend Analysis ➞

Stock Chart of Frequency Therapeutics, Inc.FREQ Frequency Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 676.085 Millions
Recent Price: 14.98    
Market Intelligence Score: 80
Day Percent Change: 5.94059%    
Day Change: -9999
Week Change: 26.6272%    
Year-to-date Change: 0.0%
FREQ Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add FREQ to Watchlist:       View:      Get Complete FREQ Trend Analysis ➞

Stock Chart of Ikena Oncology, Inc.IKNA Ikena Oncology, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 277 Millions
Recent Price: 17.16    
Market Intelligence Score: 80
Day Percent Change: 4.37956%    
Day Change: -9999
Week Change: 10.8527%    
Year-to-date Change: -13.3%
IKNA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add IKNA to Watchlist:       View:      Get Complete IKNA Trend Analysis ➞

Stock Chart of Orchestra BioMed Holdings IncOBIO Orchestra BioMed Holdings Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 148.38 Millions
Recent Price: 2.66    
Market Intelligence Score: 80
Day Percent Change: 4.31373%    
Day Change: 0.06
Week Change: 9.91736%    
Year-to-date Change: -50.6%
OBIO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add OBIO to Watchlist:       View:      Get Complete OBIO Trend Analysis ➞

Stock Chart of Sangamo Therapeutics IncSGMO Sangamo Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 165.1 Millions
Recent Price: 0.70    
Market Intelligence Score: 80
Day Percent Change: 3.76519%    
Day Change: 0.03
Week Change: 23.9157%    
Year-to-date Change: -38.1%
SGMO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add SGMO to Watchlist:       View:      Get Complete SGMO Trend Analysis ➞

Stock Chart of Biomea Fusion IncBMEA Biomea Fusion Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 114.26 Millions
Recent Price: 2.09    
Market Intelligence Score: 80
Day Percent Change: 3.46535%    
Day Change: 0.01
Week Change: 5.02513%    
Year-to-date Change: -43.4%
BMEA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add BMEA to Watchlist:       View:      Get Complete BMEA Trend Analysis ➞

Stock Chart of Annexon IncANNX Annexon Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 238.45 Millions
Recent Price: 3.12    
Market Intelligence Score: 80
Day Percent Change: 2.9703%    
Day Change: 0.03
Week Change: 10.6383%    
Year-to-date Change: -43.3%
ANNX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ANNX to Watchlist:       View:      Get Complete ANNX Trend Analysis ➞

Stock Chart of Trillium Therapeutics Inc.TRIL Trillium Therapeutics Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 250.885 Millions
Recent Price: 56.00    
Market Intelligence Score: 80
Day Percent Change: 2.88444%    
Day Change: -9999
Week Change: 203.688%    
Year-to-date Change: 0.0%
TRIL Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add TRIL to Watchlist:       View:      Get Complete TRIL Trend Analysis ➞

Stock Chart of Coherus Oncology IncCHRS Coherus Oncology Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 149.93 Millions
Recent Price: 1.66    
Market Intelligence Score: 80
Day Percent Change: 2.46914%    
Day Change: 0.06
Week Change: 5.06329%    
Year-to-date Change: 18.6%
CHRS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CHRS to Watchlist:       View:      Get Complete CHRS Trend Analysis ➞

Stock Chart of MorphoSys AGMOR MorphoSys AG
Sector: Health Care
SubSector: Biotechnology
MarketCap: 2636.85 Millions
Recent Price: 18.96    
Market Intelligence Score: 80
Day Percent Change: 2.43112%    
Day Change: -9999
Week Change: 3.21176%    
Year-to-date Change: 0.0%
MOR Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add MOR to Watchlist:       View:      Get Complete MOR Trend Analysis ➞

Stock Chart of Tarsus Pharmaceuticals IncTARS Tarsus Pharmaceuticals Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 2432.8 Millions
Recent Price: 58.72    
Market Intelligence Score: 80
Day Percent Change: 2.4067%    
Day Change: 1.15
Week Change: 6.26131%    
Year-to-date Change: 6.5%
TARS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add TARS to Watchlist:       View:      Get Complete TARS Trend Analysis ➞

Stock Chart of Mannkind CorpMNKD Mannkind Corp
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1699.83 Millions
Recent Price: 5.50    
Market Intelligence Score: 80
Day Percent Change: 2.23048%    
Day Change: -0.03
Week Change: 3.18949%    
Year-to-date Change: -16.7%
MNKD Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add MNKD to Watchlist:       View:      Get Complete MNKD Trend Analysis ➞

Stock Chart of Cellectis ADRCLLS Cellectis ADR
Sector: Health Care
SubSector: Biotechnology
MarketCap: 193.2 Millions
Recent Price: 3.36    
Market Intelligence Score: 80
Day Percent Change: 2.12766%    
Day Change: -0.05
Week Change: -3.17003%    
Year-to-date Change: 85.6%
CLLS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CLLS to Watchlist:       View:      Get Complete CLLS Trend Analysis ➞

Stock Chart of Achillion Pharmaceuticals, Inc.ACHN Achillion Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 552.38 Millions
Recent Price: 22.80    
Market Intelligence Score: 80
Day Percent Change: 1.92222%    
Day Change: -9999
Week Change: 10033.3%    
Year-to-date Change: 0.0%
ACHN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ACHN to Watchlist:       View:      Get Complete ACHN Trend Analysis ➞

Stock Chart of Viking Therapeutics IncVKTX Viking Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 3033.77 Millions
Recent Price: 27.88    
Market Intelligence Score: 80
Day Percent Change: 1.86335%    
Day Change: -0.03
Week Change: 4.69395%    
Year-to-date Change: -32.2%
VKTX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add VKTX to Watchlist:       View:      Get Complete VKTX Trend Analysis ➞

Stock Chart of Lineage Cell Therapeutics IncLCTX Lineage Cell Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 278.59 Millions
Recent Price: 1.72    
Market Intelligence Score: 80
Day Percent Change: 1.77515%    
Day Change: -0.02
Week Change: 7.5%    
Year-to-date Change: 234.0%
LCTX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add LCTX to Watchlist:       View:      Get Complete LCTX Trend Analysis ➞

Stock Chart of Aldeyra Therapeutics IncALDX Aldeyra Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 333.02 Millions
Recent Price: 5.32    
Market Intelligence Score: 80
Day Percent Change: 1.52672%    
Day Change: 0.25
Week Change: 6.18762%    
Year-to-date Change: 1.9%
ALDX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ALDX to Watchlist:       View:      Get Complete ALDX Trend Analysis ➞

Stock Chart of InflaRx N.VIFRX InflaRx N.V
Sector: Health Care
SubSector: Biotechnology
MarketCap: 110.77 Millions
Recent Price: 1.38    
Market Intelligence Score: 80
Day Percent Change: 1.47059%    
Day Change: 0.01
Week Change: 1.47059%    
Year-to-date Change: -44.8%
IFRX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add IFRX to Watchlist:       View:      Get Complete IFRX Trend Analysis ➞

Stock Chart of MeiraGTx Holdings plcMGTX MeiraGTx Holdings plc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 618.64 Millions
Recent Price: 8.39    
Market Intelligence Score: 80
Day Percent Change: 1.45103%    
Day Change: 0.29
Week Change: 1.20627%    
Year-to-date Change: 33.8%
MGTX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add MGTX to Watchlist:       View:      Get Complete MGTX Trend Analysis ➞

Stock Chart of Biomarin Pharmaceutical IncBMRN Biomarin Pharmaceutical Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 11092.7 Millions
Recent Price: 55.57    
Market Intelligence Score: 80
Day Percent Change: 1.2942%    
Day Change: 0.6
Week Change: 3.34759%    
Year-to-date Change: -16.4%
BMRN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add BMRN to Watchlist:       View:      Get Complete BMRN Trend Analysis ➞

Stock Chart of Cascadian Therapeutics, Inc.CASC Cascadian Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 174.52 Millions
Recent Price: 18.22    
Market Intelligence Score: 80
Day Percent Change: 1.27849%    
Day Change: -9999
Week Change: 13.8039%    
Year-to-date Change: 0.0%
CASC Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CASC to Watchlist:       View:      Get Complete CASC Trend Analysis ➞

Stock Chart of Axsome Therapeutics IncAXSM Axsome Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 6246.17 Millions
Recent Price: 119.94    
Market Intelligence Score: 80
Day Percent Change: 1.15544%    
Day Change: 0.15
Week Change: 0.985097%    
Year-to-date Change: 37.4%
AXSM Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add AXSM to Watchlist:       View:      Get Complete AXSM Trend Analysis ➞

Stock Chart of Vertex Pharmaceuticals, IncVRTX Vertex Pharmaceuticals, Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 101561 Millions
Recent Price: 408.85    
Market Intelligence Score: 80
Day Percent Change: 1.14792%    
Day Change: 3.2
Week Change: 8.5577%    
Year-to-date Change: 0.8%
VRTX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add VRTX to Watchlist:       View:      Get Complete VRTX Trend Analysis ➞

Stock Chart of BioNTech SE ADRBNTX BioNTech SE ADR
Sector: Health Care
SubSector: Biotechnology
MarketCap: 27035.4 Millions
Recent Price: 103.44    
Market Intelligence Score: 80
Day Percent Change: 0.877706%    
Day Change: 0.9
Week Change: 3.69925%    
Year-to-date Change: -10.3%
BNTX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add BNTX to Watchlist:       View:      Get Complete BNTX Trend Analysis ➞

Stock Chart of Athersys, Inc.ATHX Athersys, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 305.085 Millions
Recent Price: 11.99    
Market Intelligence Score: 80
Day Percent Change: 0.841043%    
Day Change: -9999
Week Change: 193287%    
Year-to-date Change: 0.0%
ATHX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ATHX to Watchlist:       View:      Get Complete ATHX Trend Analysis ➞

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Performance: Year-to-date, Week and Day
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