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Best Biotech Stocks

Quick Read: Best Biotech Stocks List By Performances & Trends:
Daily, Weekly, Year-to-Date, Market Cap (Size) & Technical Trends
Best Biotech Stocks Views: Quick Browse View, Summary & Slide Show View

12Stocks.com Biotech Stocks Performances & Trends Daily
October 3, 2025 - All trends (long term, mid-term and short term) for Biotech sector looks good.

The overall market intelligence score is 100 (0-bearish to 100-bullish) which puts Biotech sector in short term bullish trend.

The market intelligence score from previous trading session is 90 and an improvement of trend continues.

 Year To Date Performance: 12.1001 %
 Weekly Performance: 5.2853 %
 Daily Performance: 1.18355 %
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Biotech Sector Trend
100 / 100
Here are the market intelligence trend scores of the most requested Biotech stocks at 12Stocks.com (click stock name for detailed review):

12Stocks.com: Investing in Biotech sector with Stocks
The following table helps investors and traders sort through current performance and trends (as measured by market intelligence score) of various stocks in the Biotech sector.

Quick View: Move mouse or cursor over stock symbol (ticker) to view short-term Technical chart and over stock name to view long term chart. Click on to add stock symbol to your watchlist and to view watchlist. Click on any ticker or stock name for detailed market intelligence report for that stock.

12Stocks.com Performance of Stocks in Biotech Sector

TickerStock NameWatchlistCategoryRecent PriceMarket Intelligence ScoreChange %YTD Change%
KLDOKaleido  Biotechnology0.01809,900.00NA
NLTXNeoleukin  Biotechnology15.1090332.670.00%
SYRSSyros  Biotechnology0.0270226.23-91.35%
ATNXAthenex  Biotechnology0.0150103.330.00%
TSHATaysha Gene Biotechnology4.8810053.46163.78%
DBVTDBV Technologies Biotechnology12.2510021.65276.92%
VALNValneva SE Biotechnology12.2010020.20158.48%
PRMEPrime Medicine Biotechnology6.6710019.41123.24%
APTOAptose  Biotechnology2.012017.54-71.55%
ALVRAlloVir  Biotechnology11.4710016.9210.82%
SRPTSarepta  Biotechnology22.3510015.68-81.99%
MNPRMonopar  Biotechnology97.2110014.73337.49%
CARACara  Biotechnology18.2510014.3413.49%
ABSIAbsci Corp Biotechnology3.5610013.7431.37%
ZURAZura Bio Biotechnology4.105113.71-20.40%
SPRBSpruce  Biotechnology11.3910012.49-63.79%
KALAKala Bio Biotechnology1.542012.43-80.03%
TRDAEntrada  Biotechnology5.922510.55-66.05%
REPLReplimune  Biotechnology4.656010.45-62.98%
MEIPMEI Pharma Biotechnology3.073010.4320.39%
CABACabaletta Bio Biotechnology2.5510010.399.44%
CGENCompugen  Biotechnology1.7610010.316.97%
CRSPCRISPR  Biotechnology72.8510010.1175.84%
EDITEditas Medicine Biotechnology3.881009.44196.57%
FBIOFortress  Biotechnology2.80309.3832.08%
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Performance: Year-to-date, Week and Day
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Detailed Overview of Biotech Stocks
Biotech Technical Overview, Leaders & Laggards, Top Biotech ETF Funds & Detailed Biotech Stocks List, Charts, Trends & More

Biotech Sector: Technical Analysis, Trends & YTD Performance
Biotech sector, as represented by XBI, an exchange-traded fund [ETF] that holds basket of Biotech stocks (e.g, Amgen, Celgene) is up by 12.1001% and is currently underperforming the overall market by -2.6578% year-to-date. Below is a quick view of Technical charts and trends:

XBI Weekly Chart
Long Term Trend: Very Good
Medium Term Trend: Very Good

XBI Daily Chart
Short Term Trend: Very Good
Overall Trend Score: 100
YTD Performance: 12.1001%
**Trend Scores & Views Are Only For Educational Purposes And Not For Investing


12Stocks.com: Top Performing Biotech Sector Stocks
Hot Biotech Stocks of 2025 We try to spot trends by analyzing the performances of various stocks or components within Biotech sector and try to find best performing stocks. The movers and shakers. The winners and losers.

The top performing Biotech sector stocks year to date are
Vor Biopharma[3175%] Nanobiotix ADR[581%] I-Mab ADR[358%]
Monopar [337%] Nektar [320%] DBV Technologies[277%]
Celcuity [276%] Galectin [263%] Cidara [261%]
Lineage Cell[234%] ATAI Life[221%]
View complete list of Biotech stocks by year-to-date performance

Now, more recently, over last week, the top performing Biotech sector stocks on the move are
Athersys [193287%] VBI Vaccines[86898.5%] ContraFect [47677.8%]
Clovis Oncology[39610.5%] NanoString Technologies[17224.7%] Neptune Wellness[14100%]
Achillion [10033.3%] Nymox [8258.5%] Epizyme [5739.5%]
Portola [4717.6%] Strongbridge Biopharma[3417.5%]
View complete list of Biotech stocks by weekly performance

Unfortunately not all Biotech stocks have done well this year. Investors of these stocks hope they have seen the worst and hope that these stocks are set to bounce back. The bearish stocks in this index year to date (YTD) are
Vaxxinity [-100%] Petros [-100%] Translate Bio[-95%]
Palatin Technologies[-93%] Syros [-91%] Pliant [-89%]
Affimed N.V[-87%] MoonLake Immuno[-86%] Unity nology[-86%]
Sarepta [-82%] Kala Bio[-80%] IGM [-80%]
.
Investors can get enhanced performance by riding the current stock trends. Using complex algorithms, 12Stocks.com has come up with market intelligence scores (on 0-bearish to 100-bullish scale) to identify best trending stocks. Top trending Biotech stocks are
Taysha Gene[100] DBV Technologies[100] Valneva SE[100]
Prime Medicine[100] AlloVir [100] Sarepta [100]
Monopar [100] Cara [100] Absci Corp[100]
Spruce [100] Cabaletta Bio[100] Compugen [100]
View complete list of Biotech stocks by 12Stocks.com trends

12Stocks.com: Investing in Biotech Sector using Exchange Traded Funds
The following table shows list of key exchange traded funds (ETF) that help investors track Biotech Index. For detailed view, check out our ETF Funds section of our website.

Quick View: Move mouse or cursor over ETF symbol (ticker) to view short-term Technical chart and over ETF name to view long term chart. Click on ticker or stock name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist.

12Stocks.com List of ETFs that track Biotech Index

TickerETF NameWatchlistRecent PriceMarket Intelligence ScoreChange %Week %Year-to-date %
UBIOBiotechnology  73.3480-0.0681292260.7480%
HCRFEdge Multifactor 67.142309999NA
SICKHealthcare Bear 3X 37.903609999NA
LABSBiotech Bear 1X 24.185609999NA
BTECPrincipal Healthcare Innovators 39.493001.023280%
 Market Intelligence Score (0-Bearish to 100-Bullish)
12Stocks.com: Charts, Trends, Fundamental Data and Performances of Biotech Stocks
We now take in-depth look at all Biotech stocks including charts, multi-period performances and overall trends (as measured by market intelligence score).

One can sort Biotech stocks (click link to choose) by Daily, Weekly and by Year-to-Date performances. Also, one can sort by size of the company or by market capitalization.
Select Your Default Chart Type:
Long Term Chart Daily Chart Weekly Chart 
Long Term Chart (Default)
Weekly Chart Example
Daily Chart Example
Click on stock symbol or name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist. Quick View: Move mouse or cursor over "Daily" to quickly view daily Technical stock chart and over "Weekly" to view weekly Technical stock chart.

Stock Chart of Kaleido BioSciences, Inc.KLDO Kaleido BioSciences, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 229.185 Millions
Recent Price: 0.01    
Market Intelligence Score: 80
Day Percent Change: 9900%    
Day Change: -9999
Week Change: 9900%    
Year-to-date Change: 9,900.0%
KLDO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add KLDO to Watchlist:       View:      Get Complete KLDO Trend Analysis ➞

Stock Chart of Neoleukin Therapeutics, Inc.NLTX Neoleukin Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 412.685 Millions
Recent Price: 15.10    
Market Intelligence Score: 90
Day Percent Change: 332.665%    
Day Change: -9999
Week Change: 7.85714%    
Year-to-date Change: 0.0%
NLTX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add NLTX to Watchlist:       View:      Get Complete NLTX Trend Analysis ➞

Stock Chart of Syros Pharmaceuticals, Inc.SYRS Syros Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 275.485 Millions
Recent Price: 0.02    
Market Intelligence Score: 70
Day Percent Change: 226.23%    
Day Change: -9999
Week Change: 1709.09%    
Year-to-date Change: -91.4%
SYRS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add SYRS to Watchlist:       View:      Get Complete SYRS Trend Analysis ➞

Stock Chart of Athenex, Inc.ATNX Athenex, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 631.785 Millions
Recent Price: 0.01    
Market Intelligence Score: 50
Day Percent Change: 103.333%    
Day Change: -9999
Week Change: -95.6429%    
Year-to-date Change: 0.0%
ATNX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ATNX to Watchlist:       View:      Get Complete ATNX Trend Analysis ➞

Stock Chart of Taysha Gene Therapies IncTSHA Taysha Gene Therapies Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 916.59 Millions
Recent Price: 4.88    
Market Intelligence Score: 100
Day Percent Change: 53.4591%    
Day Change: 0
Week Change: 54.9206%    
Year-to-date Change: 163.8%
TSHA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add TSHA to Watchlist:       View:      Get Complete TSHA Trend Analysis ➞

Stock Chart of DBV Technologies ADRDBVT DBV Technologies ADR
Sector: Health Care
SubSector: Biotechnology
MarketCap: 245.22 Millions
Recent Price: 12.25    
Market Intelligence Score: 100
Day Percent Change: 21.6485%    
Day Change: -0.26
Week Change: 28.9474%    
Year-to-date Change: 276.9%
DBVT Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add DBVT to Watchlist:       View:      Get Complete DBVT Trend Analysis ➞

Stock Chart of Valneva SE ADRVALN Valneva SE ADR
Sector: Health Care
SubSector: Biotechnology
MarketCap: 735.51 Millions
Recent Price: 12.20    
Market Intelligence Score: 100
Day Percent Change: 20.197%    
Day Change: -0.31
Week Change: 36.1607%    
Year-to-date Change: 158.5%
VALN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add VALN to Watchlist:       View:      Get Complete VALN Trend Analysis ➞

Stock Chart of Prime Medicine IncPRME Prime Medicine Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 662.89 Millions
Recent Price: 6.67    
Market Intelligence Score: 100
Day Percent Change: 19.4097%    
Day Change: -0.02
Week Change: 20.054%    
Year-to-date Change: 123.2%
PRME Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PRME to Watchlist:       View:      Get Complete PRME Trend Analysis ➞

Stock Chart of Aptose Biosciences Inc.APTO Aptose Biosciences Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 484.585 Millions
Recent Price: 2.01    
Market Intelligence Score: 20
Day Percent Change: 17.5439%    
Day Change: -9999
Week Change: -42.2414%    
Year-to-date Change: -71.5%
APTO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add APTO to Watchlist:       View:      Get Complete APTO Trend Analysis ➞

Stock Chart of AlloVir, Inc.ALVR AlloVir, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 25787 Millions
Recent Price: 11.47    
Market Intelligence Score: 100
Day Percent Change: 16.9215%    
Day Change: -9999
Week Change: 20.8641%    
Year-to-date Change: 10.8%
ALVR Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ALVR to Watchlist:       View:      Get Complete ALVR Trend Analysis ➞

Stock Chart of Sarepta Therapeutics IncSRPT Sarepta Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1828.22 Millions
Recent Price: 22.35    
Market Intelligence Score: 100
Day Percent Change: 15.6832%    
Day Change: 3.12
Week Change: 22.3987%    
Year-to-date Change: -82.0%
SRPT Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add SRPT to Watchlist:       View:      Get Complete SRPT Trend Analysis ➞

Stock Chart of Monopar Therapeutics IncMNPR Monopar Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 272.77 Millions
Recent Price: 97.21    
Market Intelligence Score: 100
Day Percent Change: 14.7291%    
Day Change: -1.16
Week Change: 33.0915%    
Year-to-date Change: 337.5%
MNPR Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add MNPR to Watchlist:       View:      Get Complete MNPR Trend Analysis ➞

Stock Chart of Cara Therapeutics, Inc.CARA Cara Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 597.985 Millions
Recent Price: 18.25    
Market Intelligence Score: 100
Day Percent Change: 14.3396%    
Day Change: -9999
Week Change: 25.4199%    
Year-to-date Change: 13.5%
CARA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CARA to Watchlist:       View:      Get Complete CARA Trend Analysis ➞

Stock Chart of Absci CorpABSI Absci Corp
Sector: Health Care
SubSector: Biotechnology
MarketCap: 367.83 Millions
Recent Price: 3.56    
Market Intelligence Score: 100
Day Percent Change: 13.738%    
Day Change: -0.01
Week Change: 42.9719%    
Year-to-date Change: 31.4%
ABSI Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ABSI to Watchlist:       View:      Get Complete ABSI Trend Analysis ➞

Stock Chart of Zura Bio LtdZURA Zura Bio Ltd
Sector: Health Care
SubSector: Biotechnology
MarketCap: 143.04 Millions
Recent Price: 4.10    
Market Intelligence Score: 51
Day Percent Change: 13.71%    
Day Change: 0.24
Week Change: 15.7%    
Year-to-date Change: -20.4%
ZURA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ZURA to Watchlist:       View:      Get Complete ZURA Trend Analysis ➞

Stock Chart of Spruce Biosciences, Inc.SPRB Spruce Biosciences, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 49487 Millions
Recent Price: 11.39    
Market Intelligence Score: 100
Day Percent Change: 12.4938%    
Day Change: -9999
Week Change: 39.3272%    
Year-to-date Change: -63.8%
SPRB Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add SPRB to Watchlist:       View:      Get Complete SPRB Trend Analysis ➞

Stock Chart of Kala Bio IncKALA Kala Bio Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 102.16 Millions
Recent Price: 1.54    
Market Intelligence Score: 20
Day Percent Change: 12.4252%    
Day Change: 0.16
Week Change: -91.9519%    
Year-to-date Change: -80.0%
KALA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add KALA to Watchlist:       View:      Get Complete KALA Trend Analysis ➞

Stock Chart of Entrada Therapeutics IncTRDA Entrada Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 201.22 Millions
Recent Price: 5.92    
Market Intelligence Score: 25
Day Percent Change: 10.55%    
Day Change: 0.56
Week Change: 11.81%    
Year-to-date Change: -66.1%
TRDA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add TRDA to Watchlist:       View:      Get Complete TRDA Trend Analysis ➞

Stock Chart of Replimune Group IncREPL Replimune Group Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 494.09 Millions
Recent Price: 4.65    
Market Intelligence Score: 60
Day Percent Change: 10.4513%    
Day Change: 0.35
Week Change: 11.7788%    
Year-to-date Change: -63.0%
REPL Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add REPL to Watchlist:       View:      Get Complete REPL Trend Analysis ➞

Stock Chart of MEI Pharma IncMEIP MEI Pharma Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 138.9 Millions
Recent Price: 3.07    
Market Intelligence Score: 30
Day Percent Change: 10.4317%    
Day Change: 0.03
Week Change: -36.701%    
Year-to-date Change: 20.4%
MEIP Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add MEIP to Watchlist:       View:      Get Complete MEIP Trend Analysis ➞

Stock Chart of Cabaletta Bio IncCABA Cabaletta Bio Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 155.49 Millions
Recent Price: 2.55    
Market Intelligence Score: 100
Day Percent Change: 10.3896%    
Day Change: 0.02
Week Change: 3.23887%    
Year-to-date Change: 9.4%
CABA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CABA to Watchlist:       View:      Get Complete CABA Trend Analysis ➞

Stock Chart of Compugen LtdCGEN Compugen Ltd
Sector: Health Care
SubSector: Biotechnology
MarketCap: 133.76 Millions
Recent Price: 1.76    
Market Intelligence Score: 100
Day Percent Change: 10.3125%    
Day Change: -0.01
Week Change: 26.0714%    
Year-to-date Change: 7.0%
CGEN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CGEN to Watchlist:       View:      Get Complete CGEN Trend Analysis ➞

Stock Chart of CRISPR Therapeutics AGCRSP CRISPR Therapeutics AG
Sector: Health Care
SubSector: Biotechnology
MarketCap: 4989.54 Millions
Recent Price: 72.85    
Market Intelligence Score: 100
Day Percent Change: 10.1118%    
Day Change: 2.41
Week Change: 19.3284%    
Year-to-date Change: 75.8%
CRSP Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CRSP to Watchlist:       View:      Get Complete CRSP Trend Analysis ➞

Stock Chart of Editas Medicine IncEDIT Editas Medicine Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 248.18 Millions
Recent Price: 3.88    
Market Intelligence Score: 100
Day Percent Change: 9.43662%    
Day Change: 0.06
Week Change: 15.2819%    
Year-to-date Change: 196.6%
EDIT Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add EDIT to Watchlist:       View:      Get Complete EDIT Trend Analysis ➞

Stock Chart of Fortress Biotech IncFBIO Fortress Biotech Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 110.39 Millions
Recent Price: 2.80    
Market Intelligence Score: 30
Day Percent Change: 9.375%    
Day Change: 0.19
Week Change: -24.1192%    
Year-to-date Change: 32.1%
FBIO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add FBIO to Watchlist:       View:      Get Complete FBIO Trend Analysis ➞

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Click To Change The Sort Order: By Market Cap or Company Size
Performance: Year-to-date, Week and Day
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