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Best Biotech Stocks

Quick Read: Best Biotech Stocks List By Performances & Trends:
Daily, Weekly, Year-to-Date, Market Cap (Size) & Technical Trends
Best Biotech Stocks Views: Quick Browse View, Summary & Slide Show View

12Stocks.com Biotech Stocks Performances & Trends Daily
October 3, 2025 - All trends (long term, mid-term and short term) for Biotech sector looks good.

The overall market intelligence score is 100 (0-bearish to 100-bullish) which puts Biotech sector in short term bullish trend.

The market intelligence score from previous trading session is 90 and an improvement of trend continues.

 Year To Date Performance: 12.1001 %
 Weekly Performance: 5.2853 %
 Daily Performance: 1.18355 %
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Biotech Sector Trend
100 / 100
Here are the market intelligence trend scores of the most requested Biotech stocks at 12Stocks.com (click stock name for detailed review):

12Stocks.com: Investing in Biotech sector with Stocks
The following table helps investors and traders sort through current performance and trends (as measured by market intelligence score) of various stocks in the Biotech sector.

Quick View: Move mouse or cursor over stock symbol (ticker) to view short-term Technical chart and over stock name to view long term chart. Click on to add stock symbol to your watchlist and to view watchlist. Click on any ticker or stock name for detailed market intelligence report for that stock.

12Stocks.com Performance of Stocks in Biotech Sector

TickerStock NameWatchlistCategoryRecent PriceMarket Intelligence ScoreChange %YTD Change%
RIGLRigel  Biotechnology28.1130-0.19%62.28%
PGENPrecigen  Biotechnology3.3330-0.30%208.33%
AKROAkero  Biotechnology46.4130-0.30%65.28%
LOGCLogicBio  Biotechnology7.4130-0.54%6.93%
LQDALiquidia Corp Biotechnology21.9230-0.59%81.16%
GHRSGH Research Biotechnology13.3430-1.69%68.65%
MIRMMirum  Biotechnology71.7530-1.71%70.67%
BNTCBenitec Biopharma Biotechnology13.7330-2.00%13.66%
SLNOSoleno  Biotechnology57.9830-3.56%26.84%
PHVSPharvaris NV Biotechnology23.0930-4.03%24.54%
HALOHalozyme  Biotechnology71.6930-4.34%49.32%
CRTXCortexyme  Biotechnology1.3330-5.00%0.00%
EVFMEvofem  Biotechnology0.0130-10.00%-6.25%
DSGNDesign  Biotechnology6.0130-11.41%-2.51%
TRDAEntrada  Biotechnology5.922510.55%-66.05%
APTOAptose  Biotechnology2.012017.54%-71.55%
KALAKala Bio Biotechnology1.542012.43%-80.03%
ARNAArena  Biotechnology2.34203.08%0.00%
RTRXRetrophin  Biotechnology3.67202.51%0.00%
CBMCambrex  Biotechnology18.47202.27%0.00%
CELGCelgene  Biotechnology55.13201.30%0.00%
IMMUImmunomedics  Biotechnology7.46201.22%0.00%
OBSVObsEva SA Biotechnology0.08201.20%0.00%
CBIOCrescent Biopharma Biotechnology12.03201.09%-53.73%
AGENAgenus  Biotechnology3.94201.03%27.51%
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Performance: Year-to-date, Week and Day
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Detailed Overview of Biotech Stocks
Biotech Technical Overview, Leaders & Laggards, Top Biotech ETF Funds & Detailed Biotech Stocks List, Charts, Trends & More

Biotech Sector: Technical Analysis, Trends & YTD Performance
Biotech sector, as represented by XBI, an exchange-traded fund [ETF] that holds basket of Biotech stocks (e.g, Amgen, Celgene) is up by 12.1001% and is currently underperforming the overall market by -2.6578% year-to-date. Below is a quick view of Technical charts and trends:

XBI Weekly Chart
Long Term Trend: Very Good
Medium Term Trend: Very Good

XBI Daily Chart
Short Term Trend: Very Good
Overall Trend Score: 100
YTD Performance: 12.1001%
**Trend Scores & Views Are Only For Educational Purposes And Not For Investing


12Stocks.com: Top Performing Biotech Sector Stocks
Hot Biotech Stocks of 2025 We try to spot trends by analyzing the performances of various stocks or components within Biotech sector and try to find best performing stocks. The movers and shakers. The winners and losers.

The top performing Biotech sector stocks year to date are
Vor Biopharma[3175%] Nanobiotix ADR[581%] I-Mab ADR[358%]
Monopar [337%] Nektar [320%] DBV Technologies[277%]
Celcuity [276%] Galectin [263%] Cidara [261%]
Lineage Cell[234%] ATAI Life[221%]
View complete list of Biotech stocks by year-to-date performance

Now, more recently, over last week, the top performing Biotech sector stocks on the move are
Athersys [193287%] VBI Vaccines[86898.5%] ContraFect [47677.8%]
Clovis Oncology[39610.5%] NanoString Technologies[17224.7%] Neptune Wellness[14100%]
Achillion [10033.3%] Nymox [8258.5%] Epizyme [5739.5%]
Portola [4717.6%] Strongbridge Biopharma[3417.5%]
View complete list of Biotech stocks by weekly performance

Unfortunately not all Biotech stocks have done well this year. Investors of these stocks hope they have seen the worst and hope that these stocks are set to bounce back. The bearish stocks in this index year to date (YTD) are
Vaxxinity [-100%] Petros [-100%] Translate Bio[-95%]
Palatin Technologies[-93%] Syros [-91%] Pliant [-89%]
Affimed N.V[-87%] MoonLake Immuno[-86%] Unity nology[-86%]
Sarepta [-82%] Kala Bio[-80%] IGM [-80%]
.
Investors can get enhanced performance by riding the current stock trends. Using complex algorithms, 12Stocks.com has come up with market intelligence scores (on 0-bearish to 100-bullish scale) to identify best trending stocks. Top trending Biotech stocks are
Taysha Gene[100] DBV Technologies[100] Valneva SE[100]
Prime Medicine[100] AlloVir [100] Sarepta [100]
Monopar [100] Cara [100] Absci Corp[100]
Spruce [100] Cabaletta Bio[100] Compugen [100]
View complete list of Biotech stocks by 12Stocks.com trends

12Stocks.com: Investing in Biotech Sector using Exchange Traded Funds
The following table shows list of key exchange traded funds (ETF) that help investors track Biotech Index. For detailed view, check out our ETF Funds section of our website.

Quick View: Move mouse or cursor over ETF symbol (ticker) to view short-term Technical chart and over ETF name to view long term chart. Click on ticker or stock name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist.

12Stocks.com List of ETFs that track Biotech Index

TickerETF NameWatchlistRecent PriceMarket Intelligence ScoreChange %Week %Year-to-date %
UBIOBiotechnology  73.3480-0.0681292260.7480%
HCRFEdge Multifactor 67.142309999NA
SICKHealthcare Bear 3X 37.903609999NA
LABSBiotech Bear 1X 24.185609999NA
BTECPrincipal Healthcare Innovators 39.493001.023280%
 Market Intelligence Score (0-Bearish to 100-Bullish)
12Stocks.com: Charts, Trends, Fundamental Data and Performances of Biotech Stocks
We now take in-depth look at all Biotech stocks including charts, multi-period performances and overall trends (as measured by market intelligence score).

One can sort Biotech stocks (click link to choose) by Daily, Weekly and by Year-to-Date performances. Also, one can sort by size of the company or by market capitalization.
Select Your Default Chart Type:
Long Term Chart Daily Chart Weekly Chart 
Long Term Chart (Default)
Weekly Chart Example
Daily Chart Example
Click on stock symbol or name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist. Quick View: Move mouse or cursor over "Daily" to quickly view daily Technical stock chart and over "Weekly" to view weekly Technical stock chart.

Stock Chart of Rigel PharmaceuticalsRIGL Rigel Pharmaceuticals
Sector: Health Care
SubSector: Biotechnology
MarketCap: 741.53 Millions
Recent Price: 28.11    
Market Intelligence Score: 30
Day Percent Change: -0.18821%    
Day Change: 0.63
Week Change: -7.17635%    
Year-to-date Change: 62.3%
RIGL Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add RIGL to Watchlist:       View:      Get Complete RIGL Trend Analysis ➞

Stock Chart of Precigen IncPGEN Precigen Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1299.16 Millions
Recent Price: 3.33    
Market Intelligence Score: 30
Day Percent Change: -0.299401%    
Day Change: 0.43
Week Change: -13.7306%    
Year-to-date Change: 208.3%
PGEN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PGEN to Watchlist:       View:      Get Complete PGEN Trend Analysis ➞

Stock Chart of Akero Therapeutics IncAKRO Akero Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 3577.11 Millions
Recent Price: 46.41    
Market Intelligence Score: 30
Day Percent Change: -0.300752%    
Day Change: 0.34
Week Change: -2.21239%    
Year-to-date Change: 65.3%
AKRO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add AKRO to Watchlist:       View:      Get Complete AKRO Trend Analysis ➞

Stock Chart of LogicBio Therapeutics, Inc.LOGC LogicBio Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 203.485 Millions
Recent Price: 7.41    
Market Intelligence Score: 30
Day Percent Change: -0.536913%    
Day Change: -9999
Week Change: 0.135135%    
Year-to-date Change: 6.9%
LOGC Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add LOGC to Watchlist:       View:      Get Complete LOGC Trend Analysis ➞

Stock Chart of Liquidia CorpLQDA Liquidia Corp
Sector: Health Care
SubSector: Biotechnology
MarketCap: 2483.74 Millions
Recent Price: 21.92    
Market Intelligence Score: 30
Day Percent Change: -0.589569%    
Day Change: -0.05
Week Change: -0.0911577%    
Year-to-date Change: 81.2%
LQDA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add LQDA to Watchlist:       View:      Get Complete LQDA Trend Analysis ➞

Stock Chart of GH Research PLCGHRS GH Research PLC
Sector: Health Care
SubSector: Biotechnology
MarketCap: 873.98 Millions
Recent Price: 13.34    
Market Intelligence Score: 30
Day Percent Change: -1.69492%    
Day Change: 0.21
Week Change: -2.27106%    
Year-to-date Change: 68.6%
GHRS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add GHRS to Watchlist:       View:      Get Complete GHRS Trend Analysis ➞

Stock Chart of Mirum Pharmaceuticals IncMIRM Mirum Pharmaceuticals Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 3821.08 Millions
Recent Price: 71.75    
Market Intelligence Score: 30
Day Percent Change: -1.71233%    
Day Change: 2.35
Week Change: -3.38002%    
Year-to-date Change: 70.7%
MIRM Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add MIRM to Watchlist:       View:      Get Complete MIRM Trend Analysis ➞

Stock Chart of Benitec Biopharma IncBNTC Benitec Biopharma Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 365.14 Millions
Recent Price: 13.73    
Market Intelligence Score: 30
Day Percent Change: -1.99857%    
Day Change: -0.18
Week Change: -2.555%    
Year-to-date Change: 13.7%
BNTC Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add BNTC to Watchlist:       View:      Get Complete BNTC Trend Analysis ➞

Stock Chart of Soleno Therapeutics IncSLNO Soleno Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 3707.93 Millions
Recent Price: 57.98    
Market Intelligence Score: 30
Day Percent Change: -3.55955%    
Day Change: 0.86
Week Change: -10.1085%    
Year-to-date Change: 26.8%
SLNO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add SLNO to Watchlist:       View:      Get Complete SLNO Trend Analysis ➞

Stock Chart of Pharvaris NVPHVS Pharvaris NV
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1476.48 Millions
Recent Price: 23.09    
Market Intelligence Score: 30
Day Percent Change: -4.03159%    
Day Change: 0.35
Week Change: -7.26908%    
Year-to-date Change: 24.5%
PHVS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PHVS to Watchlist:       View:      Get Complete PHVS Trend Analysis ➞

Stock Chart of Halozyme Therapeutics IncHALO Halozyme Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 8764.26 Millions
Recent Price: 71.69    
Market Intelligence Score: 30
Day Percent Change: -4.3368%    
Day Change: 0.48
Week Change: -5.2221%    
Year-to-date Change: 49.3%
HALO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add HALO to Watchlist:       View:      Get Complete HALO Trend Analysis ➞

Stock Chart of Cortexyme, Inc.CRTX Cortexyme, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1406.45 Millions
Recent Price: 1.33    
Market Intelligence Score: 30
Day Percent Change: -5%    
Day Change: -9999
Week Change: -1.48148%    
Year-to-date Change: 0.0%
CRTX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CRTX to Watchlist:       View:      Get Complete CRTX Trend Analysis ➞

Stock Chart of Evofem Biosciences, Inc.EVFM Evofem Biosciences, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 243.385 Millions
Recent Price: 0.01    
Market Intelligence Score: 30
Day Percent Change: -10%    
Day Change: -9999
Week Change: 0%    
Year-to-date Change: -6.3%
EVFM Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add EVFM to Watchlist:       View:      Get Complete EVFM Trend Analysis ➞

Stock Chart of Design Therapeutics IncDSGN Design Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 367.32 Millions
Recent Price: 6.01    
Market Intelligence Score: 30
Day Percent Change: -11.4138%    
Day Change: 0.36
Week Change: -6.59938%    
Year-to-date Change: -2.5%
DSGN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add DSGN to Watchlist:       View:      Get Complete DSGN Trend Analysis ➞

Stock Chart of Entrada Therapeutics IncTRDA Entrada Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 201.22 Millions
Recent Price: 5.92    
Market Intelligence Score: 25
Day Percent Change: 10.55%    
Day Change: 0.56
Week Change: 11.81%    
Year-to-date Change: -66.1%
TRDA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add TRDA to Watchlist:       View:      Get Complete TRDA Trend Analysis ➞

Stock Chart of Aptose Biosciences Inc.APTO Aptose Biosciences Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 484.585 Millions
Recent Price: 2.01    
Market Intelligence Score: 20
Day Percent Change: 17.5439%    
Day Change: -9999
Week Change: -42.2414%    
Year-to-date Change: -71.5%
APTO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add APTO to Watchlist:       View:      Get Complete APTO Trend Analysis ➞

Stock Chart of Kala Bio IncKALA Kala Bio Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 102.16 Millions
Recent Price: 1.54    
Market Intelligence Score: 20
Day Percent Change: 12.4252%    
Day Change: 0.16
Week Change: -91.9519%    
Year-to-date Change: -80.0%
KALA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add KALA to Watchlist:       View:      Get Complete KALA Trend Analysis ➞

Stock Chart of Arena Pharmaceuticals, Inc.ARNA Arena Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1936.25 Millions
Recent Price: 2.34    
Market Intelligence Score: 20
Day Percent Change: 3.0837%    
Day Change: -9999
Week Change: -97.6598%    
Year-to-date Change: 0.0%
ARNA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ARNA to Watchlist:       View:      Get Complete ARNA Trend Analysis ➞

Stock Chart of Retrophin, Inc.RTRX Retrophin, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 536.785 Millions
Recent Price: 3.67    
Market Intelligence Score: 20
Day Percent Change: 2.51397%    
Day Change: -9999
Week Change: -71.8774%    
Year-to-date Change: 0.0%
RTRX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add RTRX to Watchlist:       View:      Get Complete RTRX Trend Analysis ➞

Stock Chart of Cambrex CorporationCBM Cambrex Corporation
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1658 Millions
Recent Price: 18.47    
Market Intelligence Score: 20
Day Percent Change: 2.27021%    
Day Change: -9999
Week Change: -61.9175%    
Year-to-date Change: 0.0%
CBM Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CBM to Watchlist:       View:      Get Complete CBM Trend Analysis ➞

Stock Chart of Celgene CorporationCELG Celgene Corporation
Sector: Health Care
SubSector: Biotechnology
MarketCap: 99608.4 Millions
Recent Price: 55.13    
Market Intelligence Score: 20
Day Percent Change: 1.30467%    
Day Change: -9999
Week Change: -27.7457%    
Year-to-date Change: 0.0%
CELG Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CELG to Watchlist:       View:      Get Complete CELG Trend Analysis ➞

Stock Chart of Immunomedics, Inc.IMMU Immunomedics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 2639.05 Millions
Recent Price: 7.46    
Market Intelligence Score: 20
Day Percent Change: 1.22117%    
Day Change: -9999
Week Change: -68.2418%    
Year-to-date Change: 0.0%
IMMU Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add IMMU to Watchlist:       View:      Get Complete IMMU Trend Analysis ➞

Stock Chart of ObsEva SAOBSV ObsEva SA
Sector: Health Care
SubSector: Biotechnology
MarketCap: 123.585 Millions
Recent Price: 0.08    
Market Intelligence Score: 20
Day Percent Change: 1.20482%    
Day Change: -9999
Week Change: -8.79479%    
Year-to-date Change: 0.0%
OBSV Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add OBSV to Watchlist:       View:      Get Complete OBSV Trend Analysis ➞

Stock Chart of Crescent Biopharma IncCBIO Crescent Biopharma Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 197.83 Millions
Recent Price: 12.03    
Market Intelligence Score: 20
Day Percent Change: 1.09244%    
Day Change: 0.6
Week Change: -7.31895%    
Year-to-date Change: -53.7%
CBIO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CBIO to Watchlist:       View:      Get Complete CBIO Trend Analysis ➞

Stock Chart of Agenus IncAGEN Agenus Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 137.97 Millions
Recent Price: 3.94    
Market Intelligence Score: 20
Day Percent Change: 1.02564%    
Day Change: 0.06
Week Change: -7.72834%    
Year-to-date Change: 27.5%
AGEN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add AGEN to Watchlist:       View:      Get Complete AGEN Trend Analysis ➞

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Performance: Year-to-date, Week and Day
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