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Best Biotech Stocks

Quick Read: Best Biotech Stocks List By Performances & Trends:
Daily, Weekly, Year-to-Date, Market Cap (Size) & Technical Trends
Best Biotech Stocks Views: Quick Browse View, Summary & Slide Show View

12Stocks.com Biotech Stocks Performances & Trends Daily
August 29, 2025 - All trends (long term, mid-term and short term) for Biotech sector looks good.

The overall market intelligence score is 100 (0-bearish to 100-bullish) which puts Biotech sector in short term bullish trend.

The market intelligence score from previous trading session is 90 and hence an improvement of trend.

 Year To Date Performance: -3.05 %
 Weekly Performance: -1.2 %
 Daily Performance: -0.51 %
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Biotech Sector Trend
100 / 100
Here are the market intelligence trend scores of the most requested Biotech stocks at 12Stocks.com (click stock name for detailed review):

12Stocks.com: Investing in Biotech sector with Stocks
The following table helps investors and traders sort through current performance and trends (as measured by market intelligence score) of various stocks in the Biotech sector.

Quick View: Move mouse or cursor over stock symbol (ticker) to view short-term Technical chart and over stock name to view long term chart. Click on to add stock symbol to your watchlist and to view watchlist. Click on any ticker or stock name for detailed market intelligence report for that stock.

12Stocks.com Performance of Stocks in Biotech Sector

TickerStock NameWatchlistCategoryRecent PriceMarket Intelligence ScoreChange %YTD Change%
IPHAInnate Pharma Biotechnology2.10200.00%21.20%
IMRXImmuneering  Biotechnology5.197034.99%110.45%
TNGXTango  Biotechnology6.90703.85%126.86%
HUMAHumacyte  Biotechnology1.5320-5.52%-69.50%
AUTLAutolus  Biotechnology1.5701.16%-25.53%
HOOKHOOKIPA Pharma Biotechnology0.95800.43%-59.15%
VRCAVerrica  Biotechnology5.66303.24%-18.00%
ATAIAtai Life Biotechnology4.578010.58%230.08%
ACRVAcrivon  Biotechnology1.36511.54%-78.07%
DVAXDynavax Technologies Biotechnology10.26105.09%-14.25%
AGENAgenus  Biotechnology4.54201.33%66.79%
FULCFulcrum  Biotechnology6.6360-0.76%38.72%
OBIOOrchestra BioMed Biotechnology2.84402.47%-37.75%
CTMXCytomX  Biotechnology2.07503.05%97.09%
MGNXMacroGenics  Biotechnology1.7270-3.36%-55.69%
NVCTNuvectis Pharma Biotechnology6.6546-3.06%17.19%
CRBUCaribou  Biotechnology1.98602.22%15.72%
RIGLRigel  Biotechnology39.73601.52%149.64%
QSIQuantum-Si  Biotechnology1.173011.00%-58.89%
LXRXLexicon  Biotechnology1.13503.54%58.43%
MNKDMannKind  Biotechnology4.5290-0.76%-38.72%
OCULOcular Therapeutix Biotechnology12.32901.42%42.04%
PSNLPersonalis  Biotechnology4.78700.43%-19.38%
ZURAZura Bio Biotechnology2.165113.71%-20.40%
ARCTArcturus  Biotechnology17.29500.69%3.01%
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Performance: Year-to-date, Week and Day
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Detailed Overview of Biotech Stocks
Biotech Technical Overview, Leaders & Laggards, Top Biotech ETF Funds & Detailed Biotech Stocks List, Charts, Trends & More

Biotech Sector: Technical Analysis, Trends & YTD Performance
Biotech sector, as represented by XBI, an exchange-traded fund [ETF] that holds basket of Biotech stocks (e.g, Amgen, Celgene) is down by -3.05% and is currently underperforming the overall market by -10.19% year-to-date. Below is a quick view of Technical charts and trends:

XBI Weekly Chart
Long Term Trend: Very Good
Medium Term Trend: Good

XBI Daily Chart
Short Term Trend: Very Good
Overall Trend Score: 100
YTD Performance: -3.05%
**Trend Scores & Views Are Only For Educational Purposes And Not For Investing


12Stocks.com: Top Performing Biotech Sector Stocks
Hot Biotech Stocks of 2025 We try to spot trends by analyzing the performances of various stocks or components within Biotech sector and try to find best performing stocks. The movers and shakers. The winners and losers.

The top performing Biotech sector stocks year to date are
I Mab[454%] Matinas BioPharma[241%] Nanobiotix S.A[239%]
Atai Life[230%] Precigen [225%] DBV Technologies[209%]
Galectin [201%] Sol-Gel Technologies[177%] Rigel [150%]
Gossamer Bio[140%] Lineage Cell[133%] Tango [127%]
View complete list of Biotech stocks by year-to-date performance

Now, more recently, over last week, the top performing Biotech sector stocks on the move are
Precigen [96.8%] Sol-Gel Technologies[69.2%] ALX Oncology[57.3%]
Immuneering [52.3%] Minerva Neuro[34.5%] Aligos [29.7%]
Karyopharm [29.5%] CASI [27.3%] Zentalis [26.4%]
Rocket [23.1%] Tenaya [22.5%] Nanobiotix S.A[18.8%]
View complete list of Biotech stocks by weekly performance

Unfortunately not all Biotech stocks have done well this year. Investors of these stocks hope they have seen the worst and hope that these stocks are set to bounce back. The bearish stocks in this index year to date (YTD) are
NuCana [-99%] ADiTx [-98%] Adaptimmune [-89%]
Pliant [-89%] X4 [-86%] Sarepta [-84%]
Mustang Bio[-81%] RedHill Biopharma[-79%] Acrivon [-78%]
Mersana [-77%] Aligos [-75%] Rocket [-70%]
.
Investors can get enhanced performance by riding the current stock trends. Using complex algorithms, 12Stocks.com has come up with market intelligence scores (on 0-bearish to 100-bullish scale) to identify best trending stocks. Top trending Biotech stocks are
ALX Oncology[100] Precigen [100] Aligos [100]
Design [100] Keros [100] Coherus [100]
Kura Oncology[100] Denali [100] Prelude [100]
FibroGen [100] Madrigal [100] Arcus [100]
View complete list of Biotech stocks by 12Stocks.com trends

12Stocks.com: Investing in Biotech Sector using Exchange Traded Funds
The following table shows list of key exchange traded funds (ETF) that help investors track Biotech Index. For detailed view, check out our ETF Funds section of our website.

Quick View: Move mouse or cursor over ETF symbol (ticker) to view short-term Technical chart and over ETF name to view long term chart. Click on ticker or stock name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist.

12Stocks.com List of ETFs that track Biotech Index

TickerETF NameWatchlistRecent PriceMarket Intelligence ScoreChange %Week %Year-to-date %
LABDBiotech Bear 3X 5.6620-2.55-1.37-19.84%
XBIBiotech  89.83100-0.51-1.2-3.05%
IBBBiotechnology  138.59800.730.730.89%
LABUBiotech Bull 3X 70.311002.380.61-22.08%
IYHHealthcare  57.7660-0.312.14-0.44%
IHFHealthcare Providers  47.23401.290.43-10.25%
ZBIOShort Biotech 16.71603.741.01106.72%
IXJGlobal Healthcare  87.55600.821.4-2.62%
CUREHealthcare Bull 3X 80.0050-1.026.93-12.21%
BBCBio Biotechnology Clinical 22.93902.050.29-5.46%
FBTFirst NYSE 172.0780-0.150.664.14%
PBEBiotech & Genome 68.46800.311.642.9%
BIBBiotechnology  55.82601.032.4711.53%
PTHDWA Healthcare Momentum 40.06800.670.47-1.58%
BBHBiotech  165.39600.610.531.51%
BISShort Biotech 14.2740-0.99-2.37-20.83%
BBPBio Biotechnology Products 67.71900.761.0512.25%
 Market Intelligence Score (0-Bearish to 100-Bullish)
12Stocks.com: Charts, Trends, Fundamental Data and Performances of Biotech Stocks
We now take in-depth look at all Biotech stocks including charts, multi-period performances and overall trends (as measured by market intelligence score).

One can sort Biotech stocks (click link to choose) by Daily, Weekly and by Year-to-Date performances. Also, one can sort by size of the company or by market capitalization.
Select Your Default Chart Type:
Long Term Chart Daily Chart Weekly Chart 
Long Term Chart (Default)
Weekly Chart Example
Daily Chart Example
Click on stock symbol or name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist. Quick View: Move mouse or cursor over "Daily" to quickly view daily Technical stock chart and over "Weekly" to view weekly Technical stock chart.

Stock Chart of Innate Pharma S.A.IPHA Innate Pharma S.A.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 309.485 Millions
Recent Price: 2.10    
Market Intelligence Score: 20
Day Percent Change: 0%    
Day Change: 0
Week Change: 2.49%    
Year-to-date Change: 21.2%
IPHA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add IPHA to Watchlist:       View:      Get Complete IPHA Trend Analysis ➞

Stock Chart of Immuneering CorporationIMRX Immuneering Corporation
Sector: Health Care
SubSector: Biotechnology
MarketCap: 303 Millions
Recent Price: 5.19    
Market Intelligence Score: 70
Day Percent Change: 34.99%    
Day Change: 1.2
Week Change: 52.3%    
Year-to-date Change: 110.5%
IMRX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add IMRX to Watchlist:       View:      Get Complete IMRX Trend Analysis ➞

Stock Chart of Tango Therapeutics, Inc.TNGX Tango Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 302 Millions
Recent Price: 6.90    
Market Intelligence Score: 70
Day Percent Change: 3.85%    
Day Change: 0.26
Week Change: 1.3%    
Year-to-date Change: 126.9%
TNGX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add TNGX to Watchlist:       View:      Get Complete TNGX Trend Analysis ➞

Stock Chart of Humacyte, Inc.HUMA Humacyte, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 297 Millions
Recent Price: 1.53    
Market Intelligence Score: 20
Day Percent Change: -5.52%    
Day Change: -0.09
Week Change: -18.09%    
Year-to-date Change: -69.5%
HUMA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add HUMA to Watchlist:       View:      Get Complete HUMA Trend Analysis ➞

Stock Chart of Autolus Therapeutics plcAUTL Autolus Therapeutics plc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 296.285 Millions
Recent Price: 1.57    
Market Intelligence Score: 0
Day Percent Change: 1.16%    
Day Change: 0.02
Week Change: -5.41%    
Year-to-date Change: -25.5%
AUTL Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add AUTL to Watchlist:       View:      Get Complete AUTL Trend Analysis ➞

Stock Chart of HOOKIPA Pharma Inc.HOOK HOOKIPA Pharma Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 294.785 Millions
Recent Price: 0.95    
Market Intelligence Score: 80
Day Percent Change: 0.43%    
Day Change: 0
Week Change: -1.2%    
Year-to-date Change: -59.2%
HOOK Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add HOOK to Watchlist:       View:      Get Complete HOOK Trend Analysis ➞

Stock Chart of Verrica Pharmaceuticals Inc.VRCA Verrica Pharmaceuticals Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 289.585 Millions
Recent Price: 5.66    
Market Intelligence Score: 30
Day Percent Change: 3.24%    
Day Change: 0.18
Week Change: -6.67%    
Year-to-date Change: -18.0%
VRCA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add VRCA to Watchlist:       View:      Get Complete VRCA Trend Analysis ➞

Stock Chart of Atai Life Sciences N.V.ATAI Atai Life Sciences N.V.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 287 Millions
Recent Price: 4.57    
Market Intelligence Score: 80
Day Percent Change: 10.58%    
Day Change: 0.42
Week Change: 9.48%    
Year-to-date Change: 230.1%
ATAI Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ATAI to Watchlist:       View:      Get Complete ATAI Trend Analysis ➞

Stock Chart of Acrivon Therapeutics, Inc.ACRV Acrivon Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 286 Millions
Recent Price: 1.36    
Market Intelligence Score: 51
Day Percent Change: 1.54%    
Day Change: 0.02
Week Change: -5.04%    
Year-to-date Change: -78.1%
ACRV Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ACRV to Watchlist:       View:      Get Complete ACRV Trend Analysis ➞

Stock Chart of Dynavax Technologies CorporationDVAX Dynavax Technologies Corporation
Sector: Health Care
SubSector: Biotechnology
MarketCap: 276.885 Millions
Recent Price: 10.26    
Market Intelligence Score: 10
Day Percent Change: 5.09%    
Day Change: 0.53
Week Change: 3.11%    
Year-to-date Change: -14.3%
DVAX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add DVAX to Watchlist:       View:      Get Complete DVAX Trend Analysis ➞

Stock Chart of Agenus Inc.AGEN Agenus Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 274.885 Millions
Recent Price: 4.54    
Market Intelligence Score: 20
Day Percent Change: 1.33%    
Day Change: 0.06
Week Change: 0.44%    
Year-to-date Change: 66.8%
AGEN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add AGEN to Watchlist:       View:      Get Complete AGEN Trend Analysis ➞

Stock Chart of Fulcrum Therapeutics, Inc.FULC Fulcrum Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 274.785 Millions
Recent Price: 6.63    
Market Intelligence Score: 60
Day Percent Change: -0.76%    
Day Change: -0.05
Week Change: -1.21%    
Year-to-date Change: 38.7%
FULC Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add FULC to Watchlist:       View:      Get Complete FULC Trend Analysis ➞

Stock Chart of Orchestra BioMed Holdings, Inc.OBIO Orchestra BioMed Holdings, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 271 Millions
Recent Price: 2.84    
Market Intelligence Score: 40
Day Percent Change: 2.47%    
Day Change: 0.06
Week Change: -6.39%    
Year-to-date Change: -37.8%
OBIO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add OBIO to Watchlist:       View:      Get Complete OBIO Trend Analysis ➞

Stock Chart of CytomX Therapeutics, Inc.CTMX CytomX Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 264.885 Millions
Recent Price: 2.07    
Market Intelligence Score: 50
Day Percent Change: 3.05%    
Day Change: 0.06
Week Change: 15.34%    
Year-to-date Change: 97.1%
CTMX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CTMX to Watchlist:       View:      Get Complete CTMX Trend Analysis ➞

Stock Chart of MacroGenics, Inc.MGNX MacroGenics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 262.785 Millions
Recent Price: 1.72    
Market Intelligence Score: 70
Day Percent Change: -3.36%    
Day Change: -0.05
Week Change: -11.11%    
Year-to-date Change: -55.7%
MGNX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add MGNX to Watchlist:       View:      Get Complete MGNX Trend Analysis ➞

Stock Chart of Nuvectis Pharma, Inc.NVCT Nuvectis Pharma, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 258 Millions
Recent Price: 6.65    
Market Intelligence Score: 46
Day Percent Change: -3.06%    
Day Change: -0.2
Week Change: -1.4%    
Year-to-date Change: 17.2%
NVCT Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add NVCT to Watchlist:       View:      Get Complete NVCT Trend Analysis ➞

Stock Chart of Caribou Biosciences, Inc.CRBU Caribou Biosciences, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 258 Millions
Recent Price: 1.98    
Market Intelligence Score: 60
Day Percent Change: 2.22%    
Day Change: 0.04
Week Change: -8%    
Year-to-date Change: 15.7%
CRBU Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CRBU to Watchlist:       View:      Get Complete CRBU Trend Analysis ➞

Stock Chart of Rigel Pharmaceuticals, Inc.RIGL Rigel Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 256.585 Millions
Recent Price: 39.73    
Market Intelligence Score: 60
Day Percent Change: 1.52%    
Day Change: 0.63
Week Change: 10.82%    
Year-to-date Change: 149.6%
RIGL Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add RIGL to Watchlist:       View:      Get Complete RIGL Trend Analysis ➞

Stock Chart of Quantum-Si incorporatedQSI Quantum-Si incorporated
Sector: Health Care
SubSector: Biotechnology
MarketCap: 256 Millions
Recent Price: 1.17    
Market Intelligence Score: 30
Day Percent Change: 11%    
Day Change: 0.11
Week Change: -0.89%    
Year-to-date Change: -58.9%
QSI Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add QSI to Watchlist:       View:      Get Complete QSI Trend Analysis ➞

Stock Chart of Lexicon Pharmaceuticals, Inc.LXRX Lexicon Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 251.185 Millions
Recent Price: 1.13    
Market Intelligence Score: 50
Day Percent Change: 3.54%    
Day Change: 0.04
Week Change: -0.85%    
Year-to-date Change: 58.4%
LXRX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add LXRX to Watchlist:       View:      Get Complete LXRX Trend Analysis ➞

Stock Chart of MannKind CorporationMNKD MannKind Corporation
Sector: Health Care
SubSector: Biotechnology
MarketCap: 250.885 Millions
Recent Price: 4.52    
Market Intelligence Score: 90
Day Percent Change: -0.76%    
Day Change: -0.03
Week Change: 6.49%    
Year-to-date Change: -38.7%
MNKD Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add MNKD to Watchlist:       View:      Get Complete MNKD Trend Analysis ➞

Stock Chart of Ocular Therapeutix, Inc.OCUL Ocular Therapeutix, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 249.985 Millions
Recent Price: 12.32    
Market Intelligence Score: 90
Day Percent Change: 1.42%    
Day Change: 0.17
Week Change: -4.11%    
Year-to-date Change: 42.0%
OCUL Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add OCUL to Watchlist:       View:      Get Complete OCUL Trend Analysis ➞

Stock Chart of Personalis, Inc.PSNL Personalis, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 242.385 Millions
Recent Price: 4.78    
Market Intelligence Score: 70
Day Percent Change: 0.43%    
Day Change: 0.02
Week Change: 0%    
Year-to-date Change: -19.4%
PSNL Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PSNL to Watchlist:       View:      Get Complete PSNL Trend Analysis ➞

Stock Chart of Zura Bio LimitedZURA Zura Bio Limited
Sector: Health Care
SubSector: Biotechnology
MarketCap: 242 Millions
Recent Price: 2.16    
Market Intelligence Score: 51
Day Percent Change: 13.71%    
Day Change: 0.24
Week Change: 15.7%    
Year-to-date Change: -20.4%
ZURA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ZURA to Watchlist:       View:      Get Complete ZURA Trend Analysis ➞

Stock Chart of Arcturus Therapeutics Holdings Inc.ARCT Arcturus Therapeutics Holdings Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 241.385 Millions
Recent Price: 17.29    
Market Intelligence Score: 50
Day Percent Change: 0.69%    
Day Change: 0.12
Week Change: -9.1%    
Year-to-date Change: 3.0%
ARCT Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ARCT to Watchlist:       View:      Get Complete ARCT Trend Analysis ➞

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Performance: Year-to-date, Week and Day
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