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Best Biotech Stocks

Quick Read: Best Biotech Stocks List By Performances & Trends:
Daily, Weekly, Year-to-Date, Market Cap (Size) & Technical Trends
Best Biotech Stocks Views: Quick Browse View, Summary & Slide Show View

12Stocks.com Biotech Stocks Performances & Trends Daily
August 29, 2025 - All trends (long term, mid-term and short term) for Biotech sector looks good.

The overall market intelligence score is 100 (0-bearish to 100-bullish) which puts Biotech sector in short term bullish trend.

The market intelligence score from previous trading session is 90 and hence an improvement of trend.

 Year To Date Performance: -3.34 %
 Weekly Performance: -1.5 %
 Daily Performance: -0.81 %
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Biotech Sector Trend
100 / 100
Here are the market intelligence trend scores of the most requested Biotech stocks at 12Stocks.com (click stock name for detailed review):

12Stocks.com: Investing in Biotech sector with Stocks
The following table helps investors and traders sort through current performance and trends (as measured by market intelligence score) of various stocks in the Biotech sector.

Quick View: Move mouse or cursor over stock symbol (ticker) to view short-term Technical chart and over stock name to view long term chart. Click on to add stock symbol to your watchlist and to view watchlist. Click on any ticker or stock name for detailed market intelligence report for that stock.

12Stocks.com Performance of Stocks in Biotech Sector

TickerStock NameWatchlistCategoryRecent PriceMarket Intelligence ScoreChange %YTD Change%
PBYIPuma nology Biotechnology5.10502.15%71.15%
CRNXCrinetics  Biotechnology30.40801.07%-42.50%
NUVBNuvation Bio Biotechnology2.95901.11%3.01%
ADAPAdaptimmune  Biotechnology0.06402.45%-89.14%
NVAXNovavax  Biotechnology7.5860-12.70%-5.10%
URGNUroGen Pharma Biotechnology19.54702.43%85.73%
BCRXBioCryst  Biotechnology8.52400.00%11.44%
RAPTRAPT  Biotechnology11.65803.88%-15.19%
REPLReplimune  Biotechnology5.53206.67%-53.76%
DSGNDesign  Biotechnology5.291007.52%-16.53%
SNDXSyndax  Biotechnology16.26900.64%19.82%
CPRXCatalyst  Biotechnology20.19501.08%-1.49%
PRTAProthena  Biotechnology8.56500.47%-38.19%
ACIUAC Immune Biotechnology2.0750-1.87%-22.22%
CRBPCorbus  Biotechnology10.47605.21%-17.80%
AVDLAvadel  Biotechnology14.87604.00%41.01%
CUECue Biopharma Biotechnology0.83500.37%-25.56%
GLUEMonte Rosa Biotechnology4.67901.58%-35.16%
MISTMilestone  Biotechnology1.77904.27%-27.54%
BOLDAudentes  Biotechnology1.14600.00%-60.69%
DTILPrecision  Biotechnology5.01801.72%24.41%
PRQRProQR  Biotechnology2.21603.27%-16.60%
BTXBioTime  Biotechnology7.1160-0.56%2.91%
VYGRVoyager  Biotechnology3.42400.30%-40.74%
MIRMMirum  Biotechnology74.651003.52%67.01%
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Performance: Year-to-date, Week and Day
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Detailed Overview of Biotech Stocks
Biotech Technical Overview, Leaders & Laggards, Top Biotech ETF Funds & Detailed Biotech Stocks List, Charts, Trends & More

Biotech Sector: Technical Analysis, Trends & YTD Performance
Biotech sector, as represented by XBI, an exchange-traded fund [ETF] that holds basket of Biotech stocks (e.g, Amgen, Celgene) is down by -3.34% and is currently underperforming the overall market by -10.57% year-to-date. Below is a quick view of Technical charts and trends:

XBI Weekly Chart
Long Term Trend: Very Good
Medium Term Trend: Good

XBI Daily Chart
Short Term Trend: Very Good
Overall Trend Score: 100
YTD Performance: -3.34%
**Trend Scores & Views Are Only For Educational Purposes And Not For Investing


12Stocks.com: Top Performing Biotech Sector Stocks
Hot Biotech Stocks of 2025 We try to spot trends by analyzing the performances of various stocks or components within Biotech sector and try to find best performing stocks. The movers and shakers. The winners and losers.

The top performing Biotech sector stocks year to date are
I Mab[454%] Matinas BioPharma[241%] Nanobiotix S.A[239%]
Atai Life[230%] Precigen [225%] DBV Technologies[209%]
Galectin [201%] Sol-Gel Technologies[177%] Rigel [150%]
Gossamer Bio[140%] Lineage Cell[133%] Tango [127%]
View complete list of Biotech stocks by year-to-date performance

Now, more recently, over last week, the top performing Biotech sector stocks on the move are
Precigen [96.8%] Sol-Gel Technologies[69.2%] ALX Oncology[57.3%]
Immuneering [52.3%] Minerva Neuro[34.5%] Aligos [29.7%]
Karyopharm [29.5%] CASI [27.3%] Zentalis [26.4%]
Rocket [23.1%] Tenaya [22.5%] Nanobiotix S.A[18.8%]
View complete list of Biotech stocks by weekly performance

Unfortunately not all Biotech stocks have done well this year. Investors of these stocks hope they have seen the worst and hope that these stocks are set to bounce back. The bearish stocks in this index year to date (YTD) are
NuCana [-99%] ADiTx [-98%] Adaptimmune [-89%]
Pliant [-89%] X4 [-86%] Sarepta [-84%]
Mustang Bio[-81%] RedHill Biopharma[-79%] Acrivon [-78%]
Mersana [-77%] Aligos [-75%] Rocket [-70%]
.
Investors can get enhanced performance by riding the current stock trends. Using complex algorithms, 12Stocks.com has come up with market intelligence scores (on 0-bearish to 100-bullish scale) to identify best trending stocks. Top trending Biotech stocks are
ALX Oncology[100] Precigen [100] Aligos [100]
Design [100] Keros [100] Coherus [100]
Kura Oncology[100] Denali [100] Prelude [100]
FibroGen [100] Madrigal [100] Arcus [100]
View complete list of Biotech stocks by 12Stocks.com trends

12Stocks.com: Investing in Biotech Sector using Exchange Traded Funds
The following table shows list of key exchange traded funds (ETF) that help investors track Biotech Index. For detailed view, check out our ETF Funds section of our website.

Quick View: Move mouse or cursor over ETF symbol (ticker) to view short-term Technical chart and over ETF name to view long term chart. Click on ticker or stock name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist.

12Stocks.com List of ETFs that track Biotech Index

TickerETF NameWatchlistRecent PriceMarket Intelligence ScoreChange %Week %Year-to-date %
LABDBiotech Bear 3X 5.6620-2.55-1.37-19.84%
XBIBiotech  89.56100-0.81-1.5-3.34%
IBBBiotechnology  138.59800.730.730.89%
LABUBiotech Bull 3X 70.311002.380.61-22.08%
IYHHealthcare  57.7660-0.312.14-0.44%
ZBIOShort Biotech 16.71603.741.01106.72%
IXJGlobal Healthcare  87.55600.821.4-2.62%
CUREHealthcare Bull 3X 80.0050-1.026.93-12.21%
IHFHealthcare Providers  47.05400.90.04-10.59%
BBCBio Biotechnology Clinical 22.93902.050.29-5.46%
FBTFirst NYSE 172.0780-0.150.664.14%
PBEBiotech & Genome 68.46800.311.642.9%
BIBBiotechnology  55.82601.032.4711.53%
PTHDWA Healthcare Momentum 40.06800.670.47-1.58%
BBHBiotech  165.39600.610.531.51%
BISShort Biotech 14.2740-0.99-2.37-20.83%
BBPBio Biotechnology Products 67.71900.761.0512.25%
 Market Intelligence Score (0-Bearish to 100-Bullish)
12Stocks.com: Charts, Trends, Fundamental Data and Performances of Biotech Stocks
We now take in-depth look at all Biotech stocks including charts, multi-period performances and overall trends (as measured by market intelligence score).

One can sort Biotech stocks (click link to choose) by Daily, Weekly and by Year-to-Date performances. Also, one can sort by size of the company or by market capitalization.
Select Your Default Chart Type:
Long Term Chart Daily Chart Weekly Chart 
Long Term Chart (Default)
Weekly Chart Example
Daily Chart Example
Click on stock symbol or name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist. Quick View: Move mouse or cursor over "Daily" to quickly view daily Technical stock chart and over "Weekly" to view weekly Technical stock chart.

Stock Chart of Puma Biotechnology, Inc.PBYI Puma Biotechnology, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 385.585 Millions
Recent Price: 5.10    
Market Intelligence Score: 50
Day Percent Change: 2.15%    
Day Change: 0.11
Week Change: -1.88%    
Year-to-date Change: 71.2%
PBYI Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PBYI to Watchlist:       View:      Get Complete PBYI Trend Analysis ➞

Stock Chart of Crinetics Pharmaceuticals, Inc.CRNX Crinetics Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 381.085 Millions
Recent Price: 30.40    
Market Intelligence Score: 80
Day Percent Change: 1.07%    
Day Change: 0.31
Week Change: -0.98%    
Year-to-date Change: -42.5%
CRNX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CRNX to Watchlist:       View:      Get Complete CRNX Trend Analysis ➞

Stock Chart of Nuvation Bio Inc.NUVB Nuvation Bio Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 381 Millions
Recent Price: 2.95    
Market Intelligence Score: 90
Day Percent Change: 1.11%    
Day Change: 0.03
Week Change: -0.72%    
Year-to-date Change: 3.0%
NUVB Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add NUVB to Watchlist:       View:      Get Complete NUVB Trend Analysis ➞

Stock Chart of Adaptimmune Therapeutics plcADAP Adaptimmune Therapeutics plc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 380.985 Millions
Recent Price: 0.06    
Market Intelligence Score: 40
Day Percent Change: 2.45%    
Day Change: 0
Week Change: -19.75%    
Year-to-date Change: -89.1%
ADAP Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ADAP to Watchlist:       View:      Get Complete ADAP Trend Analysis ➞

Stock Chart of Novavax, Inc.NVAX Novavax, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 376.185 Millions
Recent Price: 7.58    
Market Intelligence Score: 60
Day Percent Change: -12.7%    
Day Change: -1.11
Week Change: -19.09%    
Year-to-date Change: -5.1%
NVAX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add NVAX to Watchlist:       View:      Get Complete NVAX Trend Analysis ➞

Stock Chart of UroGen Pharma Ltd.URGN UroGen Pharma Ltd.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 373.485 Millions
Recent Price: 19.54    
Market Intelligence Score: 70
Day Percent Change: 2.43%    
Day Change: 0.47
Week Change: -1.49%    
Year-to-date Change: 85.7%
URGN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add URGN to Watchlist:       View:      Get Complete URGN Trend Analysis ➞

Stock Chart of BioCryst Pharmaceuticals, Inc.BCRX BioCryst Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 369.385 Millions
Recent Price: 8.52    
Market Intelligence Score: 40
Day Percent Change: 0%    
Day Change: 0
Week Change: -0.83%    
Year-to-date Change: 11.4%
BCRX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add BCRX to Watchlist:       View:      Get Complete BCRX Trend Analysis ➞

Stock Chart of RAPT Therapeutics, Inc.RAPT RAPT Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 368.785 Millions
Recent Price: 11.65    
Market Intelligence Score: 80
Day Percent Change: 3.88%    
Day Change: 0.4
Week Change: -4.71%    
Year-to-date Change: -15.2%
RAPT Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add RAPT to Watchlist:       View:      Get Complete RAPT Trend Analysis ➞

Stock Chart of Replimune Group, Inc.REPL Replimune Group, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 367.885 Millions
Recent Price: 5.53    
Market Intelligence Score: 20
Day Percent Change: 6.67%    
Day Change: 0.35
Week Change: 4.67%    
Year-to-date Change: -53.8%
REPL Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add REPL to Watchlist:       View:      Get Complete REPL Trend Analysis ➞

Stock Chart of Design Therapeutics, Inc.DSGN Design Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 367 Millions
Recent Price: 5.29    
Market Intelligence Score: 100
Day Percent Change: 7.52%    
Day Change: 0.36
Week Change: -0.19%    
Year-to-date Change: -16.5%
DSGN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add DSGN to Watchlist:       View:      Get Complete DSGN Trend Analysis ➞

Stock Chart of Syndax Pharmaceuticals, Inc.SNDX Syndax Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 365.985 Millions
Recent Price: 16.26    
Market Intelligence Score: 90
Day Percent Change: 0.64%    
Day Change: 0.1
Week Change: 7.54%    
Year-to-date Change: 19.8%
SNDX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add SNDX to Watchlist:       View:      Get Complete SNDX Trend Analysis ➞

Stock Chart of Catalyst Pharmaceuticals, Inc.CPRX Catalyst Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 365.185 Millions
Recent Price: 20.19    
Market Intelligence Score: 50
Day Percent Change: 1.08%    
Day Change: 0.22
Week Change: 2.44%    
Year-to-date Change: -1.5%
CPRX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CPRX to Watchlist:       View:      Get Complete CPRX Trend Analysis ➞

Stock Chart of Prothena Corporation plcPRTA Prothena Corporation plc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 357.985 Millions
Recent Price: 8.56    
Market Intelligence Score: 50
Day Percent Change: 0.47%    
Day Change: 0.04
Week Change: 6.2%    
Year-to-date Change: -38.2%
PRTA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PRTA to Watchlist:       View:      Get Complete PRTA Trend Analysis ➞

Stock Chart of AC Immune SAACIU AC Immune SA
Sector: Health Care
SubSector: Biotechnology
MarketCap: 356.585 Millions
Recent Price: 2.07    
Market Intelligence Score: 50
Day Percent Change: -1.87%    
Day Change: -0.04
Week Change: -1.41%    
Year-to-date Change: -22.2%
ACIU Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ACIU to Watchlist:       View:      Get Complete ACIU Trend Analysis ➞

Stock Chart of Corbus Pharmaceuticals Holdings, Inc.CRBP Corbus Pharmaceuticals Holdings, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 354.885 Millions
Recent Price: 10.47    
Market Intelligence Score: 60
Day Percent Change: 5.21%    
Day Change: 0.48
Week Change: 0.73%    
Year-to-date Change: -17.8%
CRBP Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CRBP to Watchlist:       View:      Get Complete CRBP Trend Analysis ➞

Stock Chart of Avadel Pharmaceuticals plcAVDL Avadel Pharmaceuticals plc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 354.485 Millions
Recent Price: 14.87    
Market Intelligence Score: 60
Day Percent Change: 4%    
Day Change: 0.57
Week Change: 9.78%    
Year-to-date Change: 41.0%
AVDL Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add AVDL to Watchlist:       View:      Get Complete AVDL Trend Analysis ➞

Stock Chart of Cue Biopharma, Inc.CUE Cue Biopharma, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 352.785 Millions
Recent Price: 0.83    
Market Intelligence Score: 50
Day Percent Change: 0.37%    
Day Change: 0
Week Change: 2.71%    
Year-to-date Change: -25.6%
CUE Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CUE to Watchlist:       View:      Get Complete CUE Trend Analysis ➞

Stock Chart of Monte Rosa Therapeutics, Inc.GLUE Monte Rosa Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 346 Millions
Recent Price: 4.67    
Market Intelligence Score: 90
Day Percent Change: 1.58%    
Day Change: 0.07
Week Change: 3.45%    
Year-to-date Change: -35.2%
GLUE Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add GLUE to Watchlist:       View:      Get Complete GLUE Trend Analysis ➞

Stock Chart of Milestone Pharmaceuticals Inc.MIST Milestone Pharmaceuticals Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 342.685 Millions
Recent Price: 1.77    
Market Intelligence Score: 90
Day Percent Change: 4.27%    
Day Change: 0.07
Week Change: 1.79%    
Year-to-date Change: -27.5%
MIST Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add MIST to Watchlist:       View:      Get Complete MIST Trend Analysis ➞

Stock Chart of Audentes Therapeutics, Inc.BOLD Audentes Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 336.2 Millions
Recent Price: 1.14    
Market Intelligence Score: 60
Day Percent Change: 0%    
Day Change: 0
Week Change: -2.56%    
Year-to-date Change: -60.7%
BOLD Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add BOLD to Watchlist:       View:      Get Complete BOLD Trend Analysis ➞

Stock Chart of Precision BioSciences, Inc.DTIL Precision BioSciences, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 326.285 Millions
Recent Price: 5.01    
Market Intelligence Score: 80
Day Percent Change: 1.72%    
Day Change: 0.08
Week Change: -0.63%    
Year-to-date Change: 24.4%
DTIL Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add DTIL to Watchlist:       View:      Get Complete DTIL Trend Analysis ➞

Stock Chart of ProQR Therapeutics N.V.PRQR ProQR Therapeutics N.V.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 324.385 Millions
Recent Price: 2.21    
Market Intelligence Score: 60
Day Percent Change: 3.27%    
Day Change: 0.07
Week Change: 9.41%    
Year-to-date Change: -16.6%
PRQR Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PRQR to Watchlist:       View:      Get Complete PRQR Trend Analysis ➞

Stock Chart of BioTime, Inc.BTX BioTime, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 323.65 Millions
Recent Price: 7.11    
Market Intelligence Score: 60
Day Percent Change: -0.56%    
Day Change: -0.04
Week Change: -3.56%    
Year-to-date Change: 2.9%
BTX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add BTX to Watchlist:       View:      Get Complete BTX Trend Analysis ➞

Stock Chart of Voyager Therapeutics, Inc.VYGR Voyager Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 321.085 Millions
Recent Price: 3.42    
Market Intelligence Score: 40
Day Percent Change: 0.3%    
Day Change: 0.01
Week Change: -9.68%    
Year-to-date Change: -40.7%
VYGR Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add VYGR to Watchlist:       View:      Get Complete VYGR Trend Analysis ➞

Stock Chart of Mirum Pharmaceuticals, Inc.MIRM Mirum Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 309.585 Millions
Recent Price: 74.65    
Market Intelligence Score: 100
Day Percent Change: 3.52%    
Day Change: 2.35
Week Change: 6.52%    
Year-to-date Change: 67.0%
MIRM Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add MIRM to Watchlist:       View:      Get Complete MIRM Trend Analysis ➞

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Performance: Year-to-date, Week and Day
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