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Best Biotech Stocks

Quick Read: Best Biotech Stocks List By Performances & Trends:
Daily, Weekly, Year-to-Date, Market Cap (Size) & Technical Trends
Best Biotech Stocks Views: Quick Browse View, Summary & Slide Show View

12Stocks.com Biotech Stocks Performances & Trends Daily
October 3, 2025 - All trends (long term, mid-term and short term) for Biotech sector looks good.

The overall market intelligence score is 100 (0-bearish to 100-bullish) which puts Biotech sector in short term bullish trend.

The market intelligence score from previous trading session is 90 and an improvement of trend continues.

 Year To Date Performance: 12.1001 %
 Weekly Performance: 5.2853 %
 Daily Performance: 1.18355 %
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Biotech Sector Trend
100 / 100
Here are the market intelligence trend scores of the most requested Biotech stocks at 12Stocks.com (click stock name for detailed review):

12Stocks.com: Investing in Biotech sector with Stocks
The following table helps investors and traders sort through current performance and trends (as measured by market intelligence score) of various stocks in the Biotech sector.

Quick View: Move mouse or cursor over stock symbol (ticker) to view short-term Technical chart and over stock name to view long term chart. Click on to add stock symbol to your watchlist and to view watchlist. Click on any ticker or stock name for detailed market intelligence report for that stock.

12Stocks.com Performance of Stocks in Biotech Sector

TickerStock NameWatchlistCategoryRecent PriceMarket Intelligence ScoreChange %Weekly Change%
XENEXenon  Biotechnology39.201000.20%7.13%
AGIOAgios  Biotechnology39.9490-0.32%7.02%
IONSIonis  Biotechnology68.401003.95%6.94%
RCUSArcus  Biotechnology13.3770-0.82%6.87%
SPRYARS  Biotechnology10.29701.98%6.85%
KYMRKymera  Biotechnology56.00602.45%6.67%
LGNDLigand  Biotechnology180.121000.58%6.61%
NKTXNkarta  Biotechnology2.19902.82%6.31%
EXELExelixis  Biotechnology41.36700.39%6.30%
TARSTarsus  Biotechnology58.72802.41%6.26%
HUMAHumacyte  Biotechnology1.78701.42%6.25%
ALDXAldeyra  Biotechnology5.32801.53%6.19%
IOVAIovance Bio Biotechnology2.25601.81%6.13%
PTCTPTC  Biotechnology63.051001.68%5.97%
IDYAIdeaya  Biotechnology27.2080-0.58%5.96%
JAZZJazz  Biotechnology137.211000.23%5.88%
CPRXCatalyst  Biotechnology20.8570-0.29%5.84%
IRONDisc Medicine Biotechnology65.8670-1.76%5.56%
VNDAVanda  Biotechnology5.171001.37%5.51%
NUVLNuvalent  Biotechnology83.86601.55%5.43%
ARWRArrowhead  Biotechnology34.5990-1.20%5.36%
MDGLMadrigal  Biotechnology449.54900.09%5.32%
SAVACassava  Biotechnology3.431007.19%5.21%
BBIOBridgeBio Pharma Biotechnology53.2890-0.37%5.19%
DRTSAlpha Tau Biotechnology4.3790-3.10%5.17%
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Performance: Year-to-date, Week and Day
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Detailed Overview of Biotech Stocks
Biotech Technical Overview, Leaders & Laggards, Top Biotech ETF Funds & Detailed Biotech Stocks List, Charts, Trends & More

Biotech Sector: Technical Analysis, Trends & YTD Performance
Biotech sector, as represented by XBI, an exchange-traded fund [ETF] that holds basket of Biotech stocks (e.g, Amgen, Celgene) is up by 12.1001% and is currently underperforming the overall market by -2.6578% year-to-date. Below is a quick view of Technical charts and trends:

XBI Weekly Chart
Long Term Trend: Very Good
Medium Term Trend: Very Good

XBI Daily Chart
Short Term Trend: Very Good
Overall Trend Score: 100
YTD Performance: 12.1001%
**Trend Scores & Views Are Only For Educational Purposes And Not For Investing


12Stocks.com: Top Performing Biotech Sector Stocks
Hot Biotech Stocks of 2025 We try to spot trends by analyzing the performances of various stocks or components within Biotech sector and try to find best performing stocks. The movers and shakers. The winners and losers.

The top performing Biotech sector stocks year to date are
Vor Biopharma[3175%] Nanobiotix ADR[581%] I-Mab ADR[358%]
Monopar [337%] Nektar [320%] DBV Technologies[277%]
Celcuity [276%] Galectin [263%] Cidara [261%]
Lineage Cell[234%] ATAI Life[221%]
View complete list of Biotech stocks by year-to-date performance

Now, more recently, over last week, the top performing Biotech sector stocks on the move are
Athersys [193287%] VBI Vaccines[86898.5%] ContraFect [47677.8%]
Clovis Oncology[39610.5%] NanoString Technologies[17224.7%] Neptune Wellness[14100%]
Achillion [10033.3%] Nymox [8258.5%] Epizyme [5739.5%]
Portola [4717.6%] Strongbridge Biopharma[3417.5%]
View complete list of Biotech stocks by weekly performance

Unfortunately not all Biotech stocks have done well this year. Investors of these stocks hope they have seen the worst and hope that these stocks are set to bounce back. The bearish stocks in this index year to date (YTD) are
Vaxxinity [-100%] Petros [-100%] Translate Bio[-95%]
Palatin Technologies[-93%] Syros [-91%] Pliant [-89%]
Affimed N.V[-87%] MoonLake Immuno[-86%] Unity nology[-86%]
Sarepta [-82%] Kala Bio[-80%] IGM [-80%]
.
Investors can get enhanced performance by riding the current stock trends. Using complex algorithms, 12Stocks.com has come up with market intelligence scores (on 0-bearish to 100-bullish scale) to identify best trending stocks. Top trending Biotech stocks are
Taysha Gene[100] DBV Technologies[100] Valneva SE[100]
Prime Medicine[100] AlloVir [100] Sarepta [100]
Monopar [100] Cara [100] Absci Corp[100]
Spruce [100] Cabaletta Bio[100] Compugen [100]
View complete list of Biotech stocks by 12Stocks.com trends

12Stocks.com: Investing in Biotech Sector using Exchange Traded Funds
The following table shows list of key exchange traded funds (ETF) that help investors track Biotech Index. For detailed view, check out our ETF Funds section of our website.

Quick View: Move mouse or cursor over ETF symbol (ticker) to view short-term Technical chart and over ETF name to view long term chart. Click on ticker or stock name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist.

12Stocks.com List of ETFs that track Biotech Index

TickerETF NameWatchlistRecent PriceMarket Intelligence ScoreChange %Week %Year-to-date %
UBIOBiotechnology  73.3480-0.0681292260.7480%
HCRFEdge Multifactor 67.142309999NA
SICKHealthcare Bear 3X 37.903609999NA
LABSBiotech Bear 1X 24.185609999NA
BTECPrincipal Healthcare Innovators 39.493001.023280%
 Market Intelligence Score (0-Bearish to 100-Bullish)
12Stocks.com: Charts, Trends, Fundamental Data and Performances of Biotech Stocks
We now take in-depth look at all Biotech stocks including charts, multi-period performances and overall trends (as measured by market intelligence score).

One can sort Biotech stocks (click link to choose) by Daily, Weekly and by Year-to-Date performances. Also, one can sort by size of the company or by market capitalization.
Select Your Default Chart Type:
Long Term Chart Daily Chart Weekly Chart 
Long Term Chart (Default)
Weekly Chart Example
Daily Chart Example
Click on stock symbol or name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist. Quick View: Move mouse or cursor over "Daily" to quickly view daily Technical stock chart and over "Weekly" to view weekly Technical stock chart.

Stock Chart of Xenon Pharmaceuticals IncXENE Xenon Pharmaceuticals Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 3023.32 Millions
Recent Price: 39.20    
Market Intelligence Score: 100
Day Percent Change: 0.204499%    
Day Change: 0.54
Week Change: 7.1331%    
Year-to-date Change: -2.4%
XENE Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add XENE to Watchlist:       View:      Get Complete XENE Trend Analysis ➞

Stock Chart of Agios Pharmaceuticals IncAGIO Agios Pharmaceuticals Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 2092.24 Millions
Recent Price: 39.94    
Market Intelligence Score: 90
Day Percent Change: -0.324432%    
Day Change: 1.38
Week Change: 7.02036%    
Year-to-date Change: 25.4%
AGIO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add AGIO to Watchlist:       View:      Get Complete AGIO Trend Analysis ➞

Stock Chart of Ionis Pharmaceuticals IncIONS Ionis Pharmaceuticals Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 9759.53 Millions
Recent Price: 68.40    
Market Intelligence Score: 100
Day Percent Change: 3.95137%    
Day Change: 1.93
Week Change: 6.94184%    
Year-to-date Change: 97.2%
IONS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add IONS to Watchlist:       View:      Get Complete IONS Trend Analysis ➞

Stock Chart of Arcus Biosciences IncRCUS Arcus Biosciences Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1297.39 Millions
Recent Price: 13.37    
Market Intelligence Score: 70
Day Percent Change: -0.816024%    
Day Change: 0.39
Week Change: 6.8745%    
Year-to-date Change: -11.6%
RCUS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add RCUS to Watchlist:       View:      Get Complete RCUS Trend Analysis ➞

Stock Chart of ARS Pharmaceuticals IncSPRY ARS Pharmaceuticals Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 995.18 Millions
Recent Price: 10.29    
Market Intelligence Score: 70
Day Percent Change: 1.98216%    
Day Change: 0.27
Week Change: 6.85358%    
Year-to-date Change: -3.9%
SPRY Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add SPRY to Watchlist:       View:      Get Complete SPRY Trend Analysis ➞

Stock Chart of Kymera Therapeutics IncKYMR Kymera Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 3110.86 Millions
Recent Price: 56.00    
Market Intelligence Score: 60
Day Percent Change: 2.45152%    
Day Change: 0.24
Week Change: 6.66667%    
Year-to-date Change: 37.0%
KYMR Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add KYMR to Watchlist:       View:      Get Complete KYMR Trend Analysis ➞

Stock Chart of Ligand Pharmaceuticals, IncLGND Ligand Pharmaceuticals, Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 3267.73 Millions
Recent Price: 180.12    
Market Intelligence Score: 100
Day Percent Change: 0.583554%    
Day Change: 2.06
Week Change: 6.60511%    
Year-to-date Change: 66.1%
LGND Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add LGND to Watchlist:       View:      Get Complete LGND Trend Analysis ➞

Stock Chart of Nkarta IncNKTX Nkarta Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 160.52 Millions
Recent Price: 2.19    
Market Intelligence Score: 90
Day Percent Change: 2.8169%    
Day Change: 0.06
Week Change: 6.31068%    
Year-to-date Change: -12.4%
NKTX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add NKTX to Watchlist:       View:      Get Complete NKTX Trend Analysis ➞

Stock Chart of Exelixis IncEXEL Exelixis Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 10197.4 Millions
Recent Price: 41.36    
Market Intelligence Score: 70
Day Percent Change: 0.38835%    
Day Change: -0.3
Week Change: 6.29658%    
Year-to-date Change: 21.9%
EXEL Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add EXEL to Watchlist:       View:      Get Complete EXEL Trend Analysis ➞

Stock Chart of Tarsus Pharmaceuticals IncTARS Tarsus Pharmaceuticals Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 2432.8 Millions
Recent Price: 58.72    
Market Intelligence Score: 80
Day Percent Change: 2.4067%    
Day Change: 1.15
Week Change: 6.26131%    
Year-to-date Change: 6.5%
TARS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add TARS to Watchlist:       View:      Get Complete TARS Trend Analysis ➞

Stock Chart of Humacyte IncHUMA Humacyte Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 226.47 Millions
Recent Price: 1.78    
Market Intelligence Score: 70
Day Percent Change: 1.42045%    
Day Change: -0.09
Week Change: 6.25%    
Year-to-date Change: -65.5%
HUMA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add HUMA to Watchlist:       View:      Get Complete HUMA Trend Analysis ➞

Stock Chart of Aldeyra Therapeutics IncALDX Aldeyra Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 333.02 Millions
Recent Price: 5.32    
Market Intelligence Score: 80
Day Percent Change: 1.52672%    
Day Change: 0.25
Week Change: 6.18762%    
Year-to-date Change: 1.9%
ALDX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ALDX to Watchlist:       View:      Get Complete ALDX Trend Analysis ➞

Stock Chart of Iovance Biotherapeutics IncIOVA Iovance Biotherapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 901.02 Millions
Recent Price: 2.25    
Market Intelligence Score: 60
Day Percent Change: 1.80995%    
Day Change: 0.01
Week Change: 6.13208%    
Year-to-date Change: -71.1%
IOVA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add IOVA to Watchlist:       View:      Get Complete IOVA Trend Analysis ➞

Stock Chart of PTC Therapeutics IncPTCT PTC Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 4548.63 Millions
Recent Price: 63.05    
Market Intelligence Score: 100
Day Percent Change: 1.67715%    
Day Change: 0.07
Week Change: 5.96639%    
Year-to-date Change: 37.4%
PTCT Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PTCT to Watchlist:       View:      Get Complete PTCT Trend Analysis ➞

Stock Chart of Ideaya Biosciences IncIDYA Ideaya Biosciences Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 2380.4 Millions
Recent Price: 27.20    
Market Intelligence Score: 80
Day Percent Change: -0.584795%    
Day Change: 0.31
Week Change: 5.96026%    
Year-to-date Change: 8.1%
IDYA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add IDYA to Watchlist:       View:      Get Complete IDYA Trend Analysis ➞

Stock Chart of Jazz Pharmaceuticals plcJAZZ Jazz Pharmaceuticals plc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 7855.32 Millions
Recent Price: 137.21    
Market Intelligence Score: 100
Day Percent Change: 0.226443%    
Day Change: 0.51
Week Change: 5.88008%    
Year-to-date Change: 10.9%
JAZZ Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add JAZZ to Watchlist:       View:      Get Complete JAZZ Trend Analysis ➞

Stock Chart of Catalyst Pharmaceuticals IncCPRX Catalyst Pharmaceuticals Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 2483.31 Millions
Recent Price: 20.85    
Market Intelligence Score: 70
Day Percent Change: -0.286944%    
Day Change: 0.22
Week Change: 5.83756%    
Year-to-date Change: -3.1%
CPRX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CPRX to Watchlist:       View:      Get Complete CPRX Trend Analysis ➞

Stock Chart of Disc Medicine IncIRON Disc Medicine Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 2112.36 Millions
Recent Price: 65.86    
Market Intelligence Score: 70
Day Percent Change: -1.76014%    
Day Change: 1.03
Week Change: 5.56179%    
Year-to-date Change: 5.5%
IRON Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add IRON to Watchlist:       View:      Get Complete IRON Trend Analysis ➞

Stock Chart of Vanda Pharmaceuticals IncVNDA Vanda Pharmaceuticals Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 272.4 Millions
Recent Price: 5.17    
Market Intelligence Score: 100
Day Percent Change: 1.37255%    
Day Change: -0.09
Week Change: 5.5102%    
Year-to-date Change: 7.3%
VNDA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add VNDA to Watchlist:       View:      Get Complete VNDA Trend Analysis ➞

Stock Chart of Nuvalent IncNUVL Nuvalent Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 5832.56 Millions
Recent Price: 83.86    
Market Intelligence Score: 60
Day Percent Change: 1.55001%    
Day Change: 0.41
Week Change: 5.43123%    
Year-to-date Change: 4.8%
NUVL Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add NUVL to Watchlist:       View:      Get Complete NUVL Trend Analysis ➞

Stock Chart of Arrowhead Pharmaceuticals IncARWR Arrowhead Pharmaceuticals Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 4019.84 Millions
Recent Price: 34.59    
Market Intelligence Score: 90
Day Percent Change: -1.19966%    
Day Change: 0.55
Week Change: 5.36095%    
Year-to-date Change: 76.0%
ARWR Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ARWR to Watchlist:       View:      Get Complete ARWR Trend Analysis ➞

Stock Chart of Madrigal Pharmaceuticals IncMDGL Madrigal Pharmaceuticals Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 9648.69 Millions
Recent Price: 449.54    
Market Intelligence Score: 90
Day Percent Change: 0.0890591%    
Day Change: 15.43
Week Change: 5.31815%    
Year-to-date Change: 43.3%
MDGL Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add MDGL to Watchlist:       View:      Get Complete MDGL Trend Analysis ➞

Stock Chart of Cassava Sciences IncSAVA Cassava Sciences Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 104.35 Millions
Recent Price: 3.43    
Market Intelligence Score: 100
Day Percent Change: 7.1875%    
Day Change: 0.01
Week Change: 5.21472%    
Year-to-date Change: 24.7%
SAVA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add SAVA to Watchlist:       View:      Get Complete SAVA Trend Analysis ➞

Stock Chart of BridgeBio Pharma IncBBIO BridgeBio Pharma Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 10204.6 Millions
Recent Price: 53.28    
Market Intelligence Score: 90
Day Percent Change: -0.373972%    
Day Change: 1.35
Week Change: 5.1925%    
Year-to-date Change: 88.9%
BBIO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add BBIO to Watchlist:       View:      Get Complete BBIO Trend Analysis ➞

Stock Chart of Alpha Tau Medical LtdDRTS Alpha Tau Medical Ltd
Sector: Health Care
SubSector: Biotechnology
MarketCap: 304.92 Millions
Recent Price: 4.37    
Market Intelligence Score: 90
Day Percent Change: -3.10421%    
Day Change: 0.08
Week Change: 5.17449%    
Year-to-date Change: 41.0%
DRTS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add DRTS to Watchlist:       View:      Get Complete DRTS Trend Analysis ➞

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Click To Change The Sort Order: By Market Cap or Company Size
Performance: Year-to-date, Week and Day
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