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Best Biotech Stocks

Quick Read: Best Biotech Stocks List By Performances & Trends:
Daily, Weekly, Year-to-Date, Market Cap (Size) & Technical Trends
Best Biotech Stocks Views: Quick Browse View, Summary & Slide Show View

12Stocks.com Biotech Stocks Performances & Trends Daily
August 29, 2025 - All trends (long term, mid-term and short term) for Biotech sector looks good.

The overall market intelligence score is 100 (0-bearish to 100-bullish) which puts Biotech sector in short term bullish trend.

The market intelligence score from previous trading session is 90 and hence an improvement of trend.

 Year To Date Performance: -3.05 %
 Weekly Performance: -1.2 %
 Daily Performance: -0.51 %
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Biotech Sector Trend
100 / 100
Here are the market intelligence trend scores of the most requested Biotech stocks at 12Stocks.com (click stock name for detailed review):

12Stocks.com: Investing in Biotech sector with Stocks
The following table helps investors and traders sort through current performance and trends (as measured by market intelligence score) of various stocks in the Biotech sector.

Quick View: Move mouse or cursor over stock symbol (ticker) to view short-term Technical chart and over stock name to view long term chart. Click on to add stock symbol to your watchlist and to view watchlist. Click on any ticker or stock name for detailed market intelligence report for that stock.

12Stocks.com Performance of Stocks in Biotech Sector

TickerStock NameWatchlistCategoryRecent PriceMarket Intelligence ScoreChange %YTD Change%
NUVLNuvalent  Biotechnology76.13600.56%-5.91%
HALOHalozyme  Biotechnology73.18700.67%49.78%
RAREUltragenyx  Biotechnology30.08600.54%-29.83%
ALKSAlkermes  Biotechnology29.25300.31%1.04%
AXSMAxsome  Biotechnology121.861000.13%38.45%
QUREuniQure N.V Biotechnology15.75800.45%-11.95%
KODKodiak  Biotechnology9.34502.21%-2.41%
APLSApellis  Biotechnology28.22803.91%-13.44%
BHVNBiohaven  Biotechnology15.6050-0.14%-60.70%
FATEFate  Biotechnology1.1230-1.77%-32.73%
DNLIDenali  Biotechnology15.601004.96%-25.27%
VTYXVentyx  Biotechnology2.51543.52%21.00%
CRONCronos  Biotechnology2.56805.79%26.73%
ABCLAbCellera Biologics Biotechnology4.35403.12%46.76%
XNCRXencor  Biotechnology8.0280-0.93%-67.62%
GPCRStructure  Biotechnology19.00584.34%-28.58%
ACLXArcellx  Biotechnology69.90560.36%-6.42%
AMLXAmylyx  Biotechnology9.45534.98%123.02%
AXONAxovant  Biotechnology754.4360-3.51%15.68%
KPTIKaryopharm  Biotechnology7.81100-7.38%-40.66%
RXRXRecursion  Biotechnology4.89500.21%-29.29%
INSMInsmed  Biotechnology134.531002.43%92.06%
PRMEPrime Medicine Biotechnology3.4320-0.62%10.27%
TBPHTheravance Biopharma Biotechnology13.801002.02%45.16%
ZYMEZymeworks  Biotechnology14.931000.49%-1.71%
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Performance: Year-to-date, Week and Day
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Detailed Overview of Biotech Stocks
Biotech Technical Overview, Leaders & Laggards, Top Biotech ETF Funds & Detailed Biotech Stocks List, Charts, Trends & More

Biotech Sector: Technical Analysis, Trends & YTD Performance
Biotech sector, as represented by XBI, an exchange-traded fund [ETF] that holds basket of Biotech stocks (e.g, Amgen, Celgene) is down by -3.05% and is currently underperforming the overall market by -10.19% year-to-date. Below is a quick view of Technical charts and trends:

XBI Weekly Chart
Long Term Trend: Very Good
Medium Term Trend: Good

XBI Daily Chart
Short Term Trend: Very Good
Overall Trend Score: 100
YTD Performance: -3.05%
**Trend Scores & Views Are Only For Educational Purposes And Not For Investing


12Stocks.com: Top Performing Biotech Sector Stocks
Hot Biotech Stocks of 2025 We try to spot trends by analyzing the performances of various stocks or components within Biotech sector and try to find best performing stocks. The movers and shakers. The winners and losers.

The top performing Biotech sector stocks year to date are
I Mab[454%] Matinas BioPharma[241%] Nanobiotix S.A[239%]
Atai Life[230%] Precigen [225%] DBV Technologies[209%]
Galectin [201%] Sol-Gel Technologies[177%] Rigel [150%]
Gossamer Bio[140%] Lineage Cell[133%] Tango [127%]
View complete list of Biotech stocks by year-to-date performance

Now, more recently, over last week, the top performing Biotech sector stocks on the move are
Precigen [96.8%] Sol-Gel Technologies[69.2%] ALX Oncology[57.3%]
Immuneering [52.3%] Minerva Neuro[34.5%] Aligos [29.7%]
Karyopharm [29.5%] CASI [27.3%] Zentalis [26.4%]
Rocket [23.1%] Tenaya [22.5%] Nanobiotix S.A[18.8%]
View complete list of Biotech stocks by weekly performance

Unfortunately not all Biotech stocks have done well this year. Investors of these stocks hope they have seen the worst and hope that these stocks are set to bounce back. The bearish stocks in this index year to date (YTD) are
NuCana [-99%] ADiTx [-98%] Adaptimmune [-89%]
Pliant [-89%] X4 [-86%] Sarepta [-84%]
Mustang Bio[-81%] RedHill Biopharma[-79%] Acrivon [-78%]
Mersana [-77%] Aligos [-75%] Rocket [-70%]
.
Investors can get enhanced performance by riding the current stock trends. Using complex algorithms, 12Stocks.com has come up with market intelligence scores (on 0-bearish to 100-bullish scale) to identify best trending stocks. Top trending Biotech stocks are
ALX Oncology[100] Precigen [100] Aligos [100]
Design [100] Keros [100] Coherus [100]
Kura Oncology[100] Denali [100] Prelude [100]
FibroGen [100] Madrigal [100] Arcus [100]
View complete list of Biotech stocks by 12Stocks.com trends

12Stocks.com: Investing in Biotech Sector using Exchange Traded Funds
The following table shows list of key exchange traded funds (ETF) that help investors track Biotech Index. For detailed view, check out our ETF Funds section of our website.

Quick View: Move mouse or cursor over ETF symbol (ticker) to view short-term Technical chart and over ETF name to view long term chart. Click on ticker or stock name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist.

12Stocks.com List of ETFs that track Biotech Index

TickerETF NameWatchlistRecent PriceMarket Intelligence ScoreChange %Week %Year-to-date %
LABDBiotech Bear 3X 5.6620-2.55-1.37-19.84%
XBIBiotech  89.83100-0.51-1.2-3.05%
IBBBiotechnology  138.59800.730.730.89%
LABUBiotech Bull 3X 70.311002.380.61-22.08%
IYHHealthcare  57.7660-0.312.14-0.44%
IHFHealthcare Providers  47.23401.290.43-10.25%
ZBIOShort Biotech 16.71603.741.01106.72%
IXJGlobal Healthcare  87.55600.821.4-2.62%
CUREHealthcare Bull 3X 80.0050-1.026.93-12.21%
BBCBio Biotechnology Clinical 22.93902.050.29-5.46%
FBTFirst NYSE 172.0780-0.150.664.14%
PBEBiotech & Genome 68.46800.311.642.9%
BIBBiotechnology  55.82601.032.4711.53%
PTHDWA Healthcare Momentum 40.06800.670.47-1.58%
BBHBiotech  165.39600.610.531.51%
BISShort Biotech 14.2740-0.99-2.37-20.83%
BBPBio Biotechnology Products 67.71900.761.0512.25%
 Market Intelligence Score (0-Bearish to 100-Bullish)
12Stocks.com: Charts, Trends, Fundamental Data and Performances of Biotech Stocks
We now take in-depth look at all Biotech stocks including charts, multi-period performances and overall trends (as measured by market intelligence score).

One can sort Biotech stocks (click link to choose) by Daily, Weekly and by Year-to-Date performances. Also, one can sort by size of the company or by market capitalization.
Select Your Default Chart Type:
Long Term Chart Daily Chart Weekly Chart 
Long Term Chart (Default)
Weekly Chart Example
Daily Chart Example
Click on stock symbol or name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist. Quick View: Move mouse or cursor over "Daily" to quickly view daily Technical stock chart and over "Weekly" to view weekly Technical stock chart.

Stock Chart of Nuvalent, Inc.NUVL Nuvalent, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 2400 Millions
Recent Price: 76.13    
Market Intelligence Score: 60
Day Percent Change: 0.56%    
Day Change: 0.41
Week Change: -4.1%    
Year-to-date Change: -5.9%
NUVL Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add NUVL to Watchlist:       View:      Get Complete NUVL Trend Analysis ➞

Stock Chart of Halozyme Therapeutics, Inc.HALO Halozyme Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 2383.75 Millions
Recent Price: 73.18    
Market Intelligence Score: 70
Day Percent Change: 0.67%    
Day Change: 0.48
Week Change: 9.26%    
Year-to-date Change: 49.8%
HALO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add HALO to Watchlist:       View:      Get Complete HALO Trend Analysis ➞

Stock Chart of Ultragenyx Pharmaceutical Inc.RARE Ultragenyx Pharmaceutical Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 2373.35 Millions
Recent Price: 30.08    
Market Intelligence Score: 60
Day Percent Change: 0.54%    
Day Change: 0.16
Week Change: 1.76%    
Year-to-date Change: -29.8%
RARE Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add RARE to Watchlist:       View:      Get Complete RARE Trend Analysis ➞

Stock Chart of Alkermes plcALKS Alkermes plc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 2311.95 Millions
Recent Price: 29.25    
Market Intelligence Score: 30
Day Percent Change: 0.31%    
Day Change: 0.09
Week Change: 2.83%    
Year-to-date Change: 1.0%
ALKS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ALKS to Watchlist:       View:      Get Complete ALKS Trend Analysis ➞

Stock Chart of Axsome Therapeutics, Inc.AXSM Axsome Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 2284.25 Millions
Recent Price: 121.86    
Market Intelligence Score: 100
Day Percent Change: 0.13%    
Day Change: 0.15
Week Change: 7.71%    
Year-to-date Change: 38.5%
AXSM Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add AXSM to Watchlist:       View:      Get Complete AXSM Trend Analysis ➞

Stock Chart of uniQure N.V.QURE uniQure N.V.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 2267.25 Millions
Recent Price: 15.75    
Market Intelligence Score: 80
Day Percent Change: 0.45%    
Day Change: 0.07
Week Change: -1.46%    
Year-to-date Change: -12.0%
QURE Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add QURE to Watchlist:       View:      Get Complete QURE Trend Analysis ➞

Stock Chart of Kodiak Sciences Inc.KOD Kodiak Sciences Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 2132.15 Millions
Recent Price: 9.34    
Market Intelligence Score: 50
Day Percent Change: 2.21%    
Day Change: 0.21
Week Change: -3.29%    
Year-to-date Change: -2.4%
KOD Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add KOD to Watchlist:       View:      Get Complete KOD Trend Analysis ➞

Stock Chart of Apellis Pharmaceuticals, Inc.APLS Apellis Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 2030.95 Millions
Recent Price: 28.22    
Market Intelligence Score: 80
Day Percent Change: 3.91%    
Day Change: 1.04
Week Change: 0%    
Year-to-date Change: -13.4%
APLS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add APLS to Watchlist:       View:      Get Complete APLS Trend Analysis ➞

Stock Chart of Biohaven Pharmaceutical Holding Company Ltd.BHVN Biohaven Pharmaceutical Holding Company Ltd.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 2024.25 Millions
Recent Price: 15.60    
Market Intelligence Score: 50
Day Percent Change: -0.14%    
Day Change: -0.02
Week Change: 3.16%    
Year-to-date Change: -60.7%
BHVN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add BHVN to Watchlist:       View:      Get Complete BHVN Trend Analysis ➞

Stock Chart of Fate Therapeutics, Inc.FATE Fate Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 2022.45 Millions
Recent Price: 1.12    
Market Intelligence Score: 30
Day Percent Change: -1.77%    
Day Change: -0.02
Week Change: 3.74%    
Year-to-date Change: -32.7%
FATE Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add FATE to Watchlist:       View:      Get Complete FATE Trend Analysis ➞

Stock Chart of Denali Therapeutics Inc.DNLI Denali Therapeutics Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 2020.05 Millions
Recent Price: 15.60    
Market Intelligence Score: 100
Day Percent Change: 4.96%    
Day Change: 0.72
Week Change: 5.33%    
Year-to-date Change: -25.3%
DNLI Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add DNLI to Watchlist:       View:      Get Complete DNLI Trend Analysis ➞

Stock Chart of Ventyx Biosciences, Inc.VTYX Ventyx Biosciences, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1950 Millions
Recent Price: 2.51    
Market Intelligence Score: 54
Day Percent Change: 3.52%    
Day Change: 0.09
Week Change: -11.67%    
Year-to-date Change: 21.0%
VTYX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add VTYX to Watchlist:       View:      Get Complete VTYX Trend Analysis ➞

Stock Chart of Cronos Group Inc.CRON Cronos Group Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1935.95 Millions
Recent Price: 2.56    
Market Intelligence Score: 80
Day Percent Change: 5.79%    
Day Change: 0.14
Week Change: 1.59%    
Year-to-date Change: 26.7%
CRON Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CRON to Watchlist:       View:      Get Complete CRON Trend Analysis ➞

Stock Chart of AbCellera Biologics Inc.ABCL AbCellera Biologics Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1870 Millions
Recent Price: 4.35    
Market Intelligence Score: 40
Day Percent Change: 3.12%    
Day Change: 0.13
Week Change: -4.44%    
Year-to-date Change: 46.8%
ABCL Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ABCL to Watchlist:       View:      Get Complete ABCL Trend Analysis ➞

Stock Chart of Xencor, Inc.XNCR Xencor, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1744.35 Millions
Recent Price: 8.02    
Market Intelligence Score: 80
Day Percent Change: -0.93%    
Day Change: -0.07
Week Change: -2.75%    
Year-to-date Change: -67.6%
XNCR Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add XNCR to Watchlist:       View:      Get Complete XNCR Trend Analysis ➞

Stock Chart of Structure Therapeutics Inc.GPCR Structure Therapeutics Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1530 Millions
Recent Price: 19.00    
Market Intelligence Score: 58
Day Percent Change: 4.34%    
Day Change: 0.81
Week Change: 4.53%    
Year-to-date Change: -28.6%
GPCR Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add GPCR to Watchlist:       View:      Get Complete GPCR Trend Analysis ➞

Stock Chart of Arcellx, Inc.ACLX Arcellx, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1530 Millions
Recent Price: 69.90    
Market Intelligence Score: 56
Day Percent Change: 0.36%    
Day Change: 0.26
Week Change: -0.13%    
Year-to-date Change: -6.4%
ACLX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ACLX to Watchlist:       View:      Get Complete ACLX Trend Analysis ➞

Stock Chart of Amylyx Pharmaceuticals, Inc.AMLX Amylyx Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1500 Millions
Recent Price: 9.45    
Market Intelligence Score: 53
Day Percent Change: 4.98%    
Day Change: 0.4
Week Change: 0.24%    
Year-to-date Change: 123.0%
AMLX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add AMLX to Watchlist:       View:      Get Complete AMLX Trend Analysis ➞

Stock Chart of Axovant Sciences Ltd.AXON Axovant Sciences Ltd.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1492.04 Millions
Recent Price: 754.43    
Market Intelligence Score: 60
Day Percent Change: -3.51%    
Day Change: -27.47
Week Change: -1.54%    
Year-to-date Change: 15.7%
AXON Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add AXON to Watchlist:       View:      Get Complete AXON Trend Analysis ➞

Stock Chart of Karyopharm Therapeutics Inc.KPTI Karyopharm Therapeutics Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1471.85 Millions
Recent Price: 7.81    
Market Intelligence Score: 100
Day Percent Change: -7.38%    
Day Change: -0.48
Week Change: 29.46%    
Year-to-date Change: -40.7%
KPTI Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add KPTI to Watchlist:       View:      Get Complete KPTI Trend Analysis ➞

Stock Chart of Recursion Pharmaceuticals, Inc.RXRX Recursion Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1470 Millions
Recent Price: 4.89    
Market Intelligence Score: 50
Day Percent Change: 0.21%    
Day Change: 0.01
Week Change: -15.25%    
Year-to-date Change: -29.3%
RXRX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add RXRX to Watchlist:       View:      Get Complete RXRX Trend Analysis ➞

Stock Chart of Insmed IncorporatedINSM Insmed Incorporated
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1452.45 Millions
Recent Price: 134.53    
Market Intelligence Score: 100
Day Percent Change: 2.43%    
Day Change: 3.15
Week Change: 3.8%    
Year-to-date Change: 92.1%
INSM Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add INSM to Watchlist:       View:      Get Complete INSM Trend Analysis ➞

Stock Chart of Prime Medicine, Inc.PRME Prime Medicine, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1440 Millions
Recent Price: 3.43    
Market Intelligence Score: 20
Day Percent Change: -0.62%    
Day Change: -0.02
Week Change: -11.54%    
Year-to-date Change: 10.3%
PRME Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PRME to Watchlist:       View:      Get Complete PRME Trend Analysis ➞

Stock Chart of Theravance Biopharma, Inc.TBPH Theravance Biopharma, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1404.55 Millions
Recent Price: 13.80    
Market Intelligence Score: 100
Day Percent Change: 2.02%    
Day Change: 0.27
Week Change: 5.56%    
Year-to-date Change: 45.2%
TBPH Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add TBPH to Watchlist:       View:      Get Complete TBPH Trend Analysis ➞

Stock Chart of Zymeworks Inc.ZYME Zymeworks Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1373.55 Millions
Recent Price: 14.93    
Market Intelligence Score: 100
Day Percent Change: 0.49%    
Day Change: 0.07
Week Change: 0.63%    
Year-to-date Change: -1.7%
ZYME Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ZYME to Watchlist:       View:      Get Complete ZYME Trend Analysis ➞

To view more stocks, click on Next / Previous arrows or select different range:
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Click To Change The Sort Order: By Market Cap or Company Size
Performance: Year-to-date, Week and Day
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