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Best Biotech Stocks

Quick Read: Best Biotech Stocks List By Performances & Trends:
Daily, Weekly, Year-to-Date, Market Cap (Size) & Technical Trends
Best Biotech Stocks Views: Quick Browse View, Summary & Slide Show View

12Stocks.com Biotech Stocks Performances & Trends Daily
October 3, 2025 - All trends (long term, mid-term and short term) for Biotech sector looks good.

The overall market intelligence score is 100 (0-bearish to 100-bullish) which puts Biotech sector in short term bullish trend.

The market intelligence score from previous trading session is 90 and an improvement of trend continues.

 Year To Date Performance: 12.1001 %
 Weekly Performance: 5.2853 %
 Daily Performance: 1.18355 %
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Biotech Sector Trend
100 / 100
Here are the market intelligence trend scores of the most requested Biotech stocks at 12Stocks.com (click stock name for detailed review):

12Stocks.com: Investing in Biotech sector with Stocks
The following table helps investors and traders sort through current performance and trends (as measured by market intelligence score) of various stocks in the Biotech sector.

Quick View: Move mouse or cursor over stock symbol (ticker) to view short-term Technical chart and over stock name to view long term chart. Click on to add stock symbol to your watchlist and to view watchlist. Click on any ticker or stock name for detailed market intelligence report for that stock.

12Stocks.com Performance of Stocks in Biotech Sector

TickerStock NameWatchlistCategoryRecent PriceMarket Intelligence ScoreChange %YTD Change%
ETNB89bio  Biotechnology14.84901.02%85.96%
CLLSCellectis ADR Biotechnology3.36802.13%85.64%
VERVVerve  Biotechnology11.13500.00%85.19%
ENTAEnanta  Biotechnology10.3360-2.64%84.79%
THTXTheratechnologies  Biotechnology3.39900.00%84.24%
LQDALiquidia Corp Biotechnology21.9230-0.59%81.16%
LXRXLexicon  Biotechnology1.3980-1.77%78.23%
ARWRArrowhead  Biotechnology34.5990-1.20%76.03%
CRSPCRISPR  Biotechnology72.8510010.11%75.84%
BDTXBlack Diamond Biotechnology3.73800.27%74.30%
CORTCorcept  Biotechnology85.53701.51%71.15%
MIRMMirum  Biotechnology71.7530-1.71%70.67%
GHRSGH Research Biotechnology13.3430-1.69%68.65%
EYPTEyePoint  Biotechnology13.49404.49%68.06%
PBYIPuma nology Biotechnology5.22100-0.95%67.31%
NTLAIntellia  Biotechnology20.441008.96%67.27%
ALECAlector  Biotechnology3.16905.33%67.20%
PTGXProtagonist  Biotechnology65.03501.61%66.83%
LGNDLigand  Biotechnology180.121000.58%66.13%
AKROAkero  Biotechnology46.4130-0.30%65.28%
RIGLRigel  Biotechnology28.1130-0.19%62.28%
RYTMRhythm  Biotechnology97.2340-2.78%61.86%
PHATPhathom  Biotechnology11.8270-3.82%61.26%
PROKProKidney Corp Biotechnology2.78806.92%60.69%
SLSSELLAS Life Biotechnology1.71501.18%59.81%
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Performance: Year-to-date, Week and Day
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Detailed Overview of Biotech Stocks
Biotech Technical Overview, Leaders & Laggards, Top Biotech ETF Funds & Detailed Biotech Stocks List, Charts, Trends & More

Biotech Sector: Technical Analysis, Trends & YTD Performance
Biotech sector, as represented by XBI, an exchange-traded fund [ETF] that holds basket of Biotech stocks (e.g, Amgen, Celgene) is up by 12.1001% and is currently underperforming the overall market by -2.6578% year-to-date. Below is a quick view of Technical charts and trends:

XBI Weekly Chart
Long Term Trend: Very Good
Medium Term Trend: Very Good

XBI Daily Chart
Short Term Trend: Very Good
Overall Trend Score: 100
YTD Performance: 12.1001%
**Trend Scores & Views Are Only For Educational Purposes And Not For Investing


12Stocks.com: Top Performing Biotech Sector Stocks
Hot Biotech Stocks of 2025 We try to spot trends by analyzing the performances of various stocks or components within Biotech sector and try to find best performing stocks. The movers and shakers. The winners and losers.

The top performing Biotech sector stocks year to date are
Vor Biopharma[3175%] Nanobiotix ADR[581%] I-Mab ADR[358%]
Monopar [337%] Nektar [320%] DBV Technologies[277%]
Celcuity [276%] Galectin [263%] Cidara [261%]
Lineage Cell[234%] ATAI Life[221%]
View complete list of Biotech stocks by year-to-date performance

Now, more recently, over last week, the top performing Biotech sector stocks on the move are
Athersys [193287%] VBI Vaccines[86898.5%] ContraFect [47677.8%]
Clovis Oncology[39610.5%] NanoString Technologies[17224.7%] Neptune Wellness[14100%]
Achillion [10033.3%] Nymox [8258.5%] Epizyme [5739.5%]
Portola [4717.6%] Strongbridge Biopharma[3417.5%]
View complete list of Biotech stocks by weekly performance

Unfortunately not all Biotech stocks have done well this year. Investors of these stocks hope they have seen the worst and hope that these stocks are set to bounce back. The bearish stocks in this index year to date (YTD) are
Vaxxinity [-100%] Petros [-100%] Translate Bio[-95%]
Palatin Technologies[-93%] Syros [-91%] Pliant [-89%]
Affimed N.V[-87%] MoonLake Immuno[-86%] Unity nology[-86%]
Sarepta [-82%] Kala Bio[-80%] IGM [-80%]
.
Investors can get enhanced performance by riding the current stock trends. Using complex algorithms, 12Stocks.com has come up with market intelligence scores (on 0-bearish to 100-bullish scale) to identify best trending stocks. Top trending Biotech stocks are
Taysha Gene[100] DBV Technologies[100] Valneva SE[100]
Prime Medicine[100] AlloVir [100] Sarepta [100]
Monopar [100] Cara [100] Absci Corp[100]
Spruce [100] Cabaletta Bio[100] Compugen [100]
View complete list of Biotech stocks by 12Stocks.com trends

12Stocks.com: Investing in Biotech Sector using Exchange Traded Funds
The following table shows list of key exchange traded funds (ETF) that help investors track Biotech Index. For detailed view, check out our ETF Funds section of our website.

Quick View: Move mouse or cursor over ETF symbol (ticker) to view short-term Technical chart and over ETF name to view long term chart. Click on ticker or stock name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist.

12Stocks.com List of ETFs that track Biotech Index

TickerETF NameWatchlistRecent PriceMarket Intelligence ScoreChange %Week %Year-to-date %
UBIOBiotechnology  73.3480-0.0681292260.7480%
HCRFEdge Multifactor 67.142309999NA
SICKHealthcare Bear 3X 37.903609999NA
LABSBiotech Bear 1X 24.185609999NA
BTECPrincipal Healthcare Innovators 39.493001.023280%
 Market Intelligence Score (0-Bearish to 100-Bullish)
12Stocks.com: Charts, Trends, Fundamental Data and Performances of Biotech Stocks
We now take in-depth look at all Biotech stocks including charts, multi-period performances and overall trends (as measured by market intelligence score).

One can sort Biotech stocks (click link to choose) by Daily, Weekly and by Year-to-Date performances. Also, one can sort by size of the company or by market capitalization.
Select Your Default Chart Type:
Long Term Chart Daily Chart Weekly Chart 
Long Term Chart (Default)
Weekly Chart Example
Daily Chart Example
Click on stock symbol or name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist. Quick View: Move mouse or cursor over "Daily" to quickly view daily Technical stock chart and over "Weekly" to view weekly Technical stock chart.

Stock Chart of 89bio IncETNB 89bio Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1315.49 Millions
Recent Price: 14.84    
Market Intelligence Score: 90
Day Percent Change: 1.0211%    
Day Change: 0.09
Week Change: 0.952381%    
Year-to-date Change: 86.0%
ETNB Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ETNB to Watchlist:       View:      Get Complete ETNB Trend Analysis ➞

Stock Chart of Cellectis ADRCLLS Cellectis ADR
Sector: Health Care
SubSector: Biotechnology
MarketCap: 193.2 Millions
Recent Price: 3.36    
Market Intelligence Score: 80
Day Percent Change: 2.12766%    
Day Change: -0.05
Week Change: -3.17003%    
Year-to-date Change: 85.6%
CLLS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CLLS to Watchlist:       View:      Get Complete CLLS Trend Analysis ➞

Stock Chart of Verve Therapeutics, Inc.VERV Verve Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1200 Millions
Recent Price: 11.13    
Market Intelligence Score: 50
Day Percent Change: 0%    
Day Change: -9999
Week Change: 1.64384%    
Year-to-date Change: 85.2%
VERV Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add VERV to Watchlist:       View:      Get Complete VERV Trend Analysis ➞

Stock Chart of Enanta Pharmaceuticals IncENTA Enanta Pharmaceuticals Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 189.19 Millions
Recent Price: 10.33    
Market Intelligence Score: 60
Day Percent Change: -2.63902%    
Day Change: -0.23
Week Change: 32.2663%    
Year-to-date Change: 84.8%
ENTA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ENTA to Watchlist:       View:      Get Complete ENTA Trend Analysis ➞

Stock Chart of Theratechnologies IncTHTX Theratechnologies Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 150.35 Millions
Recent Price: 3.39    
Market Intelligence Score: 90
Day Percent Change: 0%    
Day Change: 0
Week Change: 2.41692%    
Year-to-date Change: 84.2%
THTX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add THTX to Watchlist:       View:      Get Complete THTX Trend Analysis ➞

Stock Chart of Liquidia CorpLQDA Liquidia Corp
Sector: Health Care
SubSector: Biotechnology
MarketCap: 2483.74 Millions
Recent Price: 21.92    
Market Intelligence Score: 30
Day Percent Change: -0.589569%    
Day Change: -0.05
Week Change: -0.0911577%    
Year-to-date Change: 81.2%
LQDA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add LQDA to Watchlist:       View:      Get Complete LQDA Trend Analysis ➞

Stock Chart of Lexicon Pharmaceuticals IncLXRX Lexicon Pharmaceuticals Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 396.1 Millions
Recent Price: 1.39    
Market Intelligence Score: 80
Day Percent Change: -1.77305%    
Day Change: 0.04
Week Change: 4.13534%    
Year-to-date Change: 78.2%
LXRX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add LXRX to Watchlist:       View:      Get Complete LXRX Trend Analysis ➞

Stock Chart of Arrowhead Pharmaceuticals IncARWR Arrowhead Pharmaceuticals Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 4019.84 Millions
Recent Price: 34.59    
Market Intelligence Score: 90
Day Percent Change: -1.19966%    
Day Change: 0.55
Week Change: 5.36095%    
Year-to-date Change: 76.0%
ARWR Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ARWR to Watchlist:       View:      Get Complete ARWR Trend Analysis ➞

Stock Chart of CRISPR Therapeutics AGCRSP CRISPR Therapeutics AG
Sector: Health Care
SubSector: Biotechnology
MarketCap: 4989.54 Millions
Recent Price: 72.85    
Market Intelligence Score: 100
Day Percent Change: 10.1118%    
Day Change: 2.41
Week Change: 19.3284%    
Year-to-date Change: 75.8%
CRSP Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CRSP to Watchlist:       View:      Get Complete CRSP Trend Analysis ➞

Stock Chart of Black Diamond Therapeutics IncBDTX Black Diamond Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 167.39 Millions
Recent Price: 3.73    
Market Intelligence Score: 80
Day Percent Change: 0.268817%    
Day Change: 0.11
Week Change: 14.4172%    
Year-to-date Change: 74.3%
BDTX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add BDTX to Watchlist:       View:      Get Complete BDTX Trend Analysis ➞

Stock Chart of Corcept Therapeutics IncCORT Corcept Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 7308.58 Millions
Recent Price: 85.53    
Market Intelligence Score: 70
Day Percent Change: 1.51335%    
Day Change: 0.58
Week Change: 2.00978%    
Year-to-date Change: 71.2%
CORT Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CORT to Watchlist:       View:      Get Complete CORT Trend Analysis ➞

Stock Chart of Mirum Pharmaceuticals IncMIRM Mirum Pharmaceuticals Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 3821.08 Millions
Recent Price: 71.75    
Market Intelligence Score: 30
Day Percent Change: -1.71233%    
Day Change: 2.35
Week Change: -3.38002%    
Year-to-date Change: 70.7%
MIRM Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add MIRM to Watchlist:       View:      Get Complete MIRM Trend Analysis ➞

Stock Chart of GH Research PLCGHRS GH Research PLC
Sector: Health Care
SubSector: Biotechnology
MarketCap: 873.98 Millions
Recent Price: 13.34    
Market Intelligence Score: 30
Day Percent Change: -1.69492%    
Day Change: 0.21
Week Change: -2.27106%    
Year-to-date Change: 68.6%
GHRS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add GHRS to Watchlist:       View:      Get Complete GHRS Trend Analysis ➞

Stock Chart of EyePoint Pharmaceuticals IncEYPT EyePoint Pharmaceuticals Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 965.67 Millions
Recent Price: 13.49    
Market Intelligence Score: 40
Day Percent Change: 4.4909%    
Day Change: 0.09
Week Change: -4.15483%    
Year-to-date Change: 68.1%
EYPT Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add EYPT to Watchlist:       View:      Get Complete EYPT Trend Analysis ➞

Stock Chart of Puma Biotechnology IncPBYI Puma Biotechnology Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 253.36 Millions
Recent Price: 5.22    
Market Intelligence Score: 100
Day Percent Change: -0.948767%    
Day Change: 0.11
Week Change: 10.5932%    
Year-to-date Change: 67.3%
PBYI Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PBYI to Watchlist:       View:      Get Complete PBYI Trend Analysis ➞

Stock Chart of Intellia Therapeutics IncNTLA Intellia Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1294.6 Millions
Recent Price: 20.44    
Market Intelligence Score: 100
Day Percent Change: 8.95522%    
Day Change: -0.09
Week Change: 15.0901%    
Year-to-date Change: 67.3%
NTLA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add NTLA to Watchlist:       View:      Get Complete NTLA Trend Analysis ➞

Stock Chart of Alector IncALEC Alector Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 304.65 Millions
Recent Price: 3.16    
Market Intelligence Score: 90
Day Percent Change: 5.33333%    
Day Change: 0.07
Week Change: 0%    
Year-to-date Change: 67.2%
ALEC Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ALEC to Watchlist:       View:      Get Complete ALEC Trend Analysis ➞

Stock Chart of Protagonist Therapeutics IncPTGX Protagonist Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 3765.65 Millions
Recent Price: 65.03    
Market Intelligence Score: 50
Day Percent Change: 1.60938%    
Day Change: -0.19
Week Change: -1.395%    
Year-to-date Change: 66.8%
PTGX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PTGX to Watchlist:       View:      Get Complete PTGX Trend Analysis ➞

Stock Chart of Ligand Pharmaceuticals, IncLGND Ligand Pharmaceuticals, Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 3267.73 Millions
Recent Price: 180.12    
Market Intelligence Score: 100
Day Percent Change: 0.583554%    
Day Change: 2.06
Week Change: 6.60511%    
Year-to-date Change: 66.1%
LGND Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add LGND to Watchlist:       View:      Get Complete LGND Trend Analysis ➞

Stock Chart of Akero Therapeutics IncAKRO Akero Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 3577.11 Millions
Recent Price: 46.41    
Market Intelligence Score: 30
Day Percent Change: -0.300752%    
Day Change: 0.34
Week Change: -2.21239%    
Year-to-date Change: 65.3%
AKRO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add AKRO to Watchlist:       View:      Get Complete AKRO Trend Analysis ➞

Stock Chart of Rigel PharmaceuticalsRIGL Rigel Pharmaceuticals
Sector: Health Care
SubSector: Biotechnology
MarketCap: 741.53 Millions
Recent Price: 28.11    
Market Intelligence Score: 30
Day Percent Change: -0.18821%    
Day Change: 0.63
Week Change: -7.17635%    
Year-to-date Change: 62.3%
RIGL Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add RIGL to Watchlist:       View:      Get Complete RIGL Trend Analysis ➞

Stock Chart of Rhythm Pharmaceuticals IncRYTM Rhythm Pharmaceuticals Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 6782.82 Millions
Recent Price: 97.23    
Market Intelligence Score: 40
Day Percent Change: -2.77972%    
Day Change: 2.98
Week Change: 0.330203%    
Year-to-date Change: 61.9%
RYTM Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add RYTM to Watchlist:       View:      Get Complete RYTM Trend Analysis ➞

Stock Chart of Phathom Pharmaceuticals IncPHAT Phathom Pharmaceuticals Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 875.45 Millions
Recent Price: 11.82    
Market Intelligence Score: 70
Day Percent Change: -3.82425%    
Day Change: 0.32
Week Change: 0.939368%    
Year-to-date Change: 61.3%
PHAT Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PHAT to Watchlist:       View:      Get Complete PHAT Trend Analysis ➞

Stock Chart of ProKidney CorpPROK ProKidney Corp
Sector: Health Care
SubSector: Biotechnology
MarketCap: 662.14 Millions
Recent Price: 2.78    
Market Intelligence Score: 80
Day Percent Change: 6.92308%    
Day Change: 0.04
Week Change: 2.20588%    
Year-to-date Change: 60.7%
PROK Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PROK to Watchlist:       View:      Get Complete PROK Trend Analysis ➞

Stock Chart of SELLAS Life Sciences Group IncSLS SELLAS Life Sciences Group Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 201.12 Millions
Recent Price: 1.71    
Market Intelligence Score: 50
Day Percent Change: 1.18343%    
Day Change: -0.09
Week Change: 4.90798%    
Year-to-date Change: 59.8%
SLS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add SLS to Watchlist:       View:      Get Complete SLS Trend Analysis ➞

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Performance: Year-to-date, Week and Day
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