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Best Biotech Stocks
Quick Read: Best Biotech Stocks List By Performances & Trends:
Daily, Weekly, Year-to-Date, Market Cap (Size) & Technical Trends
Best Biotech Stocks Views: Quick Browse View, Summary & Slide Show View

12Stocks.com: Investing in Biotech sector with Stocks
The following table helps investors and traders sort through current performance and trends (as measured by market intelligence score) of various stocks in the Biotech sector.

Quick View: Move mouse or cursor over stock symbol (ticker) to view short-term Technical chart and over stock name to view long term chart. Click on to add stock symbol to your watchlist and to view watchlist. Click on any ticker or stock name for detailed market intelligence report for that stock.

12Stocks.com Performance of Stocks in Biotech Sector

TickerStock NameWatchlistCategoryRecent PriceMarket Intelligence ScoreChange %YTD Change%
LYRALyra  Biotechnology6.7041-5.64%NA
NKTRNektar  Biotechnology23.064612.50%NA
LYELLyell Immunopharma Biotechnology10.98616.85%NA
VRCAVerrica  Biotechnology6.3574-46.69%807.14%
RAPTRAPT  Biotechnology9.81463.85%520.89%
MRSNMersana  Biotechnology6.30749.93%340.56%
GBIOGeneration Bio Biotechnology4.10663.52%286.79%
GALTGalectin  Biotechnology4.15660.00%221.71%
TNGXTango  Biotechnology6.61615.18%113.92%
ADPTAdaptive nologies Biotechnology12.205310.45%103.50%
XFORX4  Biotechnology1.49382.20%103.00%
LCTXLineage Cell Biotechnology0.98446.55%95.90%
RIGLRigel  Biotechnology31.70731.88%88.47%
ALNYAlnylam  Biotechnology438.9368-0.94%86.53%
CMPXCompass  Biotechnology2.70415.88%86.21%
SANASana nology Biotechnology3.00466.18%84.05%
AKROAkero  Biotechnology50.46235.04%81.38%
AKBAAkebia  Biotechnology3.42414.08%80.00%
AGENAgenus  Biotechnology4.80465.55%75.18%
EDITEditas Medicine Biotechnology2.21542.11%74.02%
BBIOBridgeBio Pharma Biotechnology46.5863-21.54%69.75%
URGNUroGen Pharma Biotechnology17.75732.28%66.62%
SPRYARS  Biotechnology17.5049-0.15%65.88%
RYTMRhythm  Biotechnology91.98664.50%64.31%
KNSAKiniksa  Biotechnology32.15730.43%62.54%
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Performance: Year-to-date, Week and Day
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Detailed Overview of Biotech Stocks
Biotech Technical Overview, Leaders & Laggards, Top Biotech ETF Funds & Detailed Biotech Stocks List, Charts, Trends & More

Biotech Sector: Technical Analysis, Trends & YTD Performance
Biotech sector, as represented by XBI, an exchange-traded fund [ETF] that holds basket of Biotech stocks (e.g, Amgen, Celgene) is down by % and is currently underperforming the overall market by -8.39% year-to-date. Below is a quick view of Technical charts and trends:

Weekly Chart

Daily Chart
Overall Trend Score:
YTD Performance: %
**Trend Scores & Views Are Only For Educational Purposes And Not For Investing


12Stocks.com: Top Performing Biotech Sector Stocks
Hot Biotech Stocks of 2025 We try to spot trends by analyzing the performances of various stocks or components within Biotech sector and try to find best performing stocks. The movers and shakers. The winners and losers.

The top performing Biotech sector stocks year to date are
Lyra [3146%] Nektar [2380%] Lyell Immunopharma[1616%]
Verrica [807%] RAPT [521%] Mersana [341%]
Generation Bio[287%] Galectin [222%] Tango [114%]
Adaptive nologies[104%] X4 [103%] Lineage Cell[96%]
View complete list of Biotech stocks by year-to-date performance

Now, more recently, over last week, the top performing Biotech sector stocks on the move are
Y-mAbs [87.9%] Alector [48.3%] Rigel [44.7%]
SIGA Technologies[38.7%] Esperion [33.6%] ALX Oncology[30.6%]
Avidity [28.9%] Novavax [27.6%] ANI [27.5%]
Syndax [25.1%] Ardelyx [20.3%] Puma nology[20.2%]
View complete list of Biotech stocks by weekly performance

Unfortunately not all Biotech stocks have done well this year. Investors of these stocks hope they have seen the worst and hope that these stocks are set to bounce back. The bearish stocks in this index year to date (YTD) are
Pliant [-87%] Sarepta [-85%] Acrivon [-79%]
IGM [-79%] Rocket [-77%] PepGen [-72%]
Iovance Bio[-71%] Entrada [-70%] Xencor [-69%]
Arvinas [-67%] Geron [-64%] Vaxcyte [-63%]
.
Investors can get enhanced performance by riding the current stock trends. Using complex algorithms, 12Stocks.com has come up with market intelligence scores (on 0-bearish to 100-bullish scale) to identify best trending stocks. Top trending Biotech stocks are
Precigen [78] Greenwich Life[78] Arcutis Bio[74]
Mersana [74] MacroGenics [74] Esperion [74]
yte [74] ALX Oncology[74] Verrica [74]
Summit [73] XOMA [73] Wave Life[73]
View complete list of Biotech stocks by 12Stocks.com trends

12Stocks.com: Investing in Biotech Sector using Exchange Traded Funds
The following table shows list of key exchange traded funds (ETF) that help investors track Biotech Index. For detailed view, check out our ETF Funds section of our website.

Quick View: Move mouse or cursor over ETF symbol (ticker) to view short-term Technical chart and over ETF name to view long term chart. Click on ticker or stock name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist.

12Stocks.com List of ETFs that track Biotech Index

TickerETF NameWatchlistRecent PriceMarket Intelligence ScoreChange %Week %Year-to-date %
IBBBiotechnology  132.046616.19-0.75-0.04%
IHFHealthcare Providers  42.62201.484.44-11.01%
CUREHealthcare Bull 3X 69.313333.21-2.7-24.66%
IXJGlobal Healthcare  83.35280.87-0.26-3.05%
ZBIOShort Biotech 14.63170-5.0678.63%
BBHBiotech  159.346913.23-1.991.51%
BIBBiotechnology  50.80812.26-0.430.52%
BISShort Biotech 15.7318-1.90.19-12.85%
 Market Intelligence Score (0-Bearish to 100-Bullish)
12Stocks.com: Charts, Trends, Fundamental Data and Performances of Biotech Stocks
We now take in-depth look at all Biotech stocks including charts, multi-period performances and overall trends (as measured by market intelligence score).

One can sort Biotech stocks (click link to choose) by Daily, Weekly and by Year-to-Date performances. Also, one can sort by size of the company or by market capitalization.
Select Your Default Chart Type:
Long Term Chart Daily Chart Weekly Chart 
Long Term Chart (Default)
Weekly Chart Example
Daily Chart Example
Click on stock symbol or name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist. Quick View: Move mouse or cursor over "Daily" to quickly view daily Technical stock chart and over "Weekly" to view weekly Technical stock chart.

Stock Chart of Lyra Therapeutics, Inc.LYRA Lyra Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 12487 Millions
Recent Price: 6.70    
Market Intelligence Score: 41
Day Percent Change: -5.64%    
Day Change: -0.02
Week Change: 1.82%    
Year-to-date Change: 3,146.1%
LYRA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add LYRA to Watchlist:       View:      Get Complete LYRA Trend Analysis ➞

Stock Chart of Nektar TherapeuticsNKTR Nektar Therapeutics
Sector: Health Care
SubSector: Biotechnology
MarketCap: 2953.45 Millions
Recent Price: 23.06    
Market Intelligence Score: 46
Day Percent Change: 12.5%    
Day Change: 0.15
Week Change: 0.44%    
Year-to-date Change: 2,379.6%
NKTR Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add NKTR to Watchlist:       View:      Get Complete NKTR Trend Analysis ➞

Stock Chart of Lyell Immunopharma, Inc.LYEL Lyell Immunopharma, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 809 Millions
Recent Price: 10.98    
Market Intelligence Score: 61
Day Percent Change: 6.85%    
Day Change: 0.1
Week Change: -0.36%    
Year-to-date Change: 1,615.6%
LYEL Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add LYEL to Watchlist:       View:      Get Complete LYEL Trend Analysis ➞

Stock Chart of Verrica Pharmaceuticals Inc.VRCA Verrica Pharmaceuticals Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 289.585 Millions
Recent Price: 6.35    
Market Intelligence Score: 74
Day Percent Change: -46.69%    
Day Change: -2.47
Week Change: 12.59%    
Year-to-date Change: 807.1%
VRCA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add VRCA to Watchlist:       View:      Get Complete VRCA Trend Analysis ➞

Stock Chart of RAPT Therapeutics, Inc.RAPT RAPT Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 368.785 Millions
Recent Price: 9.81    
Market Intelligence Score: 46
Day Percent Change: 3.85%    
Day Change: 0.09
Week Change: -6.48%    
Year-to-date Change: 520.9%
RAPT Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add RAPT to Watchlist:       View:      Get Complete RAPT Trend Analysis ➞

Stock Chart of Mersana Therapeutics, Inc.MRSN Mersana Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 224.385 Millions
Recent Price: 6.30    
Market Intelligence Score: 74
Day Percent Change: 9.93%    
Day Change: 0.14
Week Change: -4.55%    
Year-to-date Change: 340.6%
MRSN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add MRSN to Watchlist:       View:      Get Complete MRSN Trend Analysis ➞

Stock Chart of Generation Bio Co.GBIO Generation Bio Co.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 17487 Millions
Recent Price: 4.10    
Market Intelligence Score: 66
Day Percent Change: 3.52%    
Day Change: 0.09
Week Change: -2.61%    
Year-to-date Change: 286.8%
GBIO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add GBIO to Watchlist:       View:      Get Complete GBIO Trend Analysis ➞

Stock Chart of Galectin Therapeutics, Inc.GALT Galectin Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 114.185 Millions
Recent Price: 4.15    
Market Intelligence Score: 66
Day Percent Change: 0%    
Day Change: 0
Week Change: 13.7%    
Year-to-date Change: 221.7%
GALT Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add GALT to Watchlist:       View:      Get Complete GALT Trend Analysis ➞

Stock Chart of Tango Therapeutics, Inc.TNGX Tango Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 302 Millions
Recent Price: 6.61    
Market Intelligence Score: 61
Day Percent Change: 5.18%    
Day Change: 0.57
Week Change: 1.23%    
Year-to-date Change: 113.9%
TNGX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add TNGX to Watchlist:       View:      Get Complete TNGX Trend Analysis ➞

Stock Chart of Adaptive Biotechnologies CorporationADPT Adaptive Biotechnologies Corporation
Sector: Health Care
SubSector: Biotechnology
MarketCap: 3525.75 Millions
Recent Price: 12.20    
Market Intelligence Score: 53
Day Percent Change: 10.45%    
Day Change: 0.46
Week Change: 18.1%    
Year-to-date Change: 103.5%
ADPT Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ADPT to Watchlist:       View:      Get Complete ADPT Trend Analysis ➞

Stock Chart of X4 Pharmaceuticals, Inc.XFOR X4 Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 143.385 Millions
Recent Price: 1.49    
Market Intelligence Score: 38
Day Percent Change: 2.2%    
Day Change: 0.02
Week Change: -6.88%    
Year-to-date Change: 103.0%
XFOR Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add XFOR to Watchlist:       View:      Get Complete XFOR Trend Analysis ➞

Stock Chart of Lineage Cell Therapeutics, Inc.LCTX Lineage Cell Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 141.285 Millions
Recent Price: 0.98    
Market Intelligence Score: 44
Day Percent Change: 6.55%    
Day Change: 0.06
Week Change: -0.09%    
Year-to-date Change: 95.9%
LCTX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add LCTX to Watchlist:       View:      Get Complete LCTX Trend Analysis ➞

Stock Chart of Rigel Pharmaceuticals, Inc.RIGL Rigel Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 256.585 Millions
Recent Price: 31.70    
Market Intelligence Score: 73
Day Percent Change: 1.88%    
Day Change: 0.23
Week Change: 44.68%    
Year-to-date Change: 88.5%
RIGL Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add RIGL to Watchlist:       View:      Get Complete RIGL Trend Analysis ➞

Stock Chart of Alnylam Pharmaceuticals, Inc.ALNY Alnylam Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 12793.2 Millions
Recent Price: 438.93    
Market Intelligence Score: 68
Day Percent Change: -0.94%    
Day Change: -2.6
Week Change: 9.24%    
Year-to-date Change: 86.5%
ALNY Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ALNY to Watchlist:       View:      Get Complete ALNY Trend Analysis ➞

Stock Chart of Compass Therapeutics, Inc.CMPX Compass Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 406 Millions
Recent Price: 2.70    
Market Intelligence Score: 41
Day Percent Change: 5.88%    
Day Change: 0.07
Week Change: -8.47%    
Year-to-date Change: 86.2%
CMPX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CMPX to Watchlist:       View:      Get Complete CMPX Trend Analysis ➞

Stock Chart of Sana Biotechnology, Inc.SANA Sana Biotechnology, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1210 Millions
Recent Price: 3.00    
Market Intelligence Score: 46
Day Percent Change: 6.18%    
Day Change: 0.34
Week Change: -23.27%    
Year-to-date Change: 84.1%
SANA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add SANA to Watchlist:       View:      Get Complete SANA Trend Analysis ➞

Stock Chart of Akero Therapeutics, Inc.AKRO Akero Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 675.085 Millions
Recent Price: 50.46    
Market Intelligence Score: 23
Day Percent Change: 5.04%    
Day Change: 1.31
Week Change: 4.32%    
Year-to-date Change: 81.4%
AKRO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add AKRO to Watchlist:       View:      Get Complete AKRO Trend Analysis ➞

Stock Chart of Akebia Therapeutics, Inc.AKBA Akebia Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 794.285 Millions
Recent Price: 3.42    
Market Intelligence Score: 41
Day Percent Change: 4.08%    
Day Change: 0.06
Week Change: -8.06%    
Year-to-date Change: 80.0%
AKBA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add AKBA to Watchlist:       View:      Get Complete AKBA Trend Analysis ➞

Stock Chart of Agenus Inc.AGEN Agenus Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 274.885 Millions
Recent Price: 4.80    
Market Intelligence Score: 46
Day Percent Change: 5.55%    
Day Change: 0.3
Week Change: -10.45%    
Year-to-date Change: 75.2%
AGEN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add AGEN to Watchlist:       View:      Get Complete AGEN Trend Analysis ➞

Stock Chart of Editas Medicine, Inc.EDIT Editas Medicine, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1194.95 Millions
Recent Price: 2.21    
Market Intelligence Score: 54
Day Percent Change: 2.11%    
Day Change: 0.08
Week Change: -9.43%    
Year-to-date Change: 74.0%
EDIT Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add EDIT to Watchlist:       View:      Get Complete EDIT Trend Analysis ➞

Stock Chart of BridgeBio Pharma, Inc.BBIO BridgeBio Pharma, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 3879.35 Millions
Recent Price: 46.58    
Market Intelligence Score: 63
Day Percent Change: -21.54%    
Day Change: -6.95
Week Change: -1.67%    
Year-to-date Change: 69.8%
BBIO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add BBIO to Watchlist:       View:      Get Complete BBIO Trend Analysis ➞

Stock Chart of UroGen Pharma Ltd.URGN UroGen Pharma Ltd.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 373.485 Millions
Recent Price: 17.75    
Market Intelligence Score: 73
Day Percent Change: 2.28%    
Day Change: 0.33
Week Change: -8.53%    
Year-to-date Change: 66.6%
URGN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add URGN to Watchlist:       View:      Get Complete URGN Trend Analysis ➞

Stock Chart of ARS Pharmaceuticals, Inc.SPRY ARS Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 632 Millions
Recent Price: 17.50    
Market Intelligence Score: 49
Day Percent Change: -0.15%    
Day Change: -0.02
Week Change: 1.86%    
Year-to-date Change: 65.9%
SPRY Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add SPRY to Watchlist:       View:      Get Complete SPRY Trend Analysis ➞

Stock Chart of Rhythm Pharmaceuticals, Inc.RYTM Rhythm Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 643.685 Millions
Recent Price: 91.98    
Market Intelligence Score: 66
Day Percent Change: 4.5%    
Day Change: 1.97
Week Change: 4.17%    
Year-to-date Change: 64.3%
RYTM Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add RYTM to Watchlist:       View:      Get Complete RYTM Trend Analysis ➞

Stock Chart of Kiniksa Pharmaceuticals, Ltd.KNSA Kiniksa Pharmaceuticals, Ltd.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 780.285 Millions
Recent Price: 32.15    
Market Intelligence Score: 73
Day Percent Change: 0.43%    
Day Change: 0.08
Week Change: 0.53%    
Year-to-date Change: 62.5%
KNSA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add KNSA to Watchlist:       View:      Get Complete KNSA Trend Analysis ➞

To view more stocks, click on Next / Previous arrows or select different range:
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Click To Change The Sort Order: By Market Cap or Company Size
Performance: Year-to-date, Week and Day
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Biotech Stocks With Best Up Trends [0-bearish to 100-bullish]:
Precigen [78], Greenwich Life[78], Arcutis Bio[74], Mersana [74], MacroGenics [74], Esperion [74], yte [74], ALX Oncology[74], Verrica [74], Summit [73], XOMA [73]

Best Biotech Stocks Year-to-Date:
Lyra [3146.12%], Nektar [2379.57%], Lyell Immunopharma[1615.63%], Verrica [807.14%], RAPT [520.89%], Mersana [340.56%], Generation Bio[286.79%], Galectin [221.71%], Tango [113.92%], Adaptive nologies[103.5%], X4 [103%]

Best Biotech Stocks This Week:
Y-mAbs [87.86%], Alector [48.28%], Rigel [44.68%], SIGA Technologies[38.7%], Esperion [33.57%], ALX Oncology[30.63%], Avidity [28.87%], Novavax [27.59%], ANI [27.45%], Syndax [25.05%], Ardelyx [20.32%]

Best Biotech Stocks Daily:
Corbus [827.02%], Summit [647.43%], Applied [270.13%], Crinetics [209.71%], TG [153.47%], Arbutus Biopharma[91.63%], XOMA [80.51%], Cytokinetics [79.41%], Iovance Bio[66.25%], Novavax [65.84%], Mirum [64.05%]


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