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Best Biotech Stocks

Quick Read: Best Biotech Stocks List By Performances & Trends:
Daily, Weekly, Year-to-Date, Market Cap (Size) & Technical Trends
Best Biotech Stocks Views: Quick Browse View, Summary & Slide Show View

12Stocks.com Biotech Stocks Performances & Trends Daily
October 3, 2025 - All trends (long term, mid-term and short term) for Biotech sector looks good.

The overall market intelligence score is 100 (0-bearish to 100-bullish) which puts Biotech sector in short term bullish trend.

The market intelligence score from previous trading session is 90 and an improvement of trend continues.

 Year To Date Performance: 12.1001 %
 Weekly Performance: 5.2853 %
 Daily Performance: 1.18355 %
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Biotech Sector Trend
100 / 100
Here are the market intelligence trend scores of the most requested Biotech stocks at 12Stocks.com (click stock name for detailed review):

12Stocks.com: Investing in Biotech sector with Stocks
The following table helps investors and traders sort through current performance and trends (as measured by market intelligence score) of various stocks in the Biotech sector.

Quick View: Move mouse or cursor over stock symbol (ticker) to view short-term Technical chart and over stock name to view long term chart. Click on to add stock symbol to your watchlist and to view watchlist. Click on any ticker or stock name for detailed market intelligence report for that stock.

12Stocks.com Performance of Stocks in Biotech Sector

TickerStock NameWatchlistCategoryRecent PriceMarket Intelligence ScoreChange %YTD Change%
OABIOmniAb  Biotechnology1.6010-0.31%-54.14%
JANXJanux  Biotechnology23.3120-1.65%-56.22%
OMEROmeros  Biotechnology4.21701.71%-57.21%
BHVNBiohaven  Biotechnology15.511004.66%-58.40%
GERNGeron Corp Biotechnology1.3890-2.48%-61.81%
REPLReplimune  Biotechnology4.656010.45%-62.98%
SPRBSpruce  Biotechnology11.3910012.49%-63.79%
HUMAHumacyte  Biotechnology1.78701.42%-65.54%
TRDAEntrada  Biotechnology5.922510.55%-66.05%
BCLIBrainstorm Cell Biotechnology0.65600.03%-69.85%
ATXIAvenue  Biotechnology0.58708.61%-69.95%
IOVAIovance Bio Biotechnology2.25601.81%-71.12%
APTOAptose  Biotechnology2.012017.54%-71.55%
ALLKAllakos  Biotechnology0.3350-0.06%-73.46%
RCKTRocket  Biotechnology3.21701.42%-74.80%
IGMSIGM  Biotechnology1.2710-2.31%-79.55%
KALAKala Bio Biotechnology1.542012.43%-80.03%
SRPTSarepta  Biotechnology22.3510015.68%-81.99%
UBXUnity nology Biotechnology0.160-20.04%-85.96%
MLTXMoonLake Immuno Biotechnology7.46305.67%-86.07%
AFMDAffimed N.V Biotechnology0.1820-34.95%-86.56%
PLRXPliant  Biotechnology1.50503.45%-88.70%
SYRSSyros  Biotechnology0.0270226.23%-91.35%
PTNPalatin Technologies Biotechnology0.090-44.65%-92.76%
TBIOTranslate Bio Biotechnology0.02200.00%-94.50%
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Click To Change The Sort Order: By Market Cap or Company Size
Performance: Year-to-date, Week and Day
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Detailed Overview of Biotech Stocks
Biotech Technical Overview, Leaders & Laggards, Top Biotech ETF Funds & Detailed Biotech Stocks List, Charts, Trends & More

Biotech Sector: Technical Analysis, Trends & YTD Performance
Biotech sector, as represented by XBI, an exchange-traded fund [ETF] that holds basket of Biotech stocks (e.g, Amgen, Celgene) is up by 12.1001% and is currently underperforming the overall market by -2.6578% year-to-date. Below is a quick view of Technical charts and trends:

XBI Weekly Chart
Long Term Trend: Very Good
Medium Term Trend: Very Good

XBI Daily Chart
Short Term Trend: Very Good
Overall Trend Score: 100
YTD Performance: 12.1001%
**Trend Scores & Views Are Only For Educational Purposes And Not For Investing


12Stocks.com: Top Performing Biotech Sector Stocks
Hot Biotech Stocks of 2025 We try to spot trends by analyzing the performances of various stocks or components within Biotech sector and try to find best performing stocks. The movers and shakers. The winners and losers.

The top performing Biotech sector stocks year to date are
Vor Biopharma[3175%] Nanobiotix ADR[581%] I-Mab ADR[358%]
Monopar [337%] Nektar [320%] DBV Technologies[277%]
Celcuity [276%] Galectin [263%] Cidara [261%]
Lineage Cell[234%] ATAI Life[221%]
View complete list of Biotech stocks by year-to-date performance

Now, more recently, over last week, the top performing Biotech sector stocks on the move are
Athersys [193287%] VBI Vaccines[86898.5%] ContraFect [47677.8%]
Clovis Oncology[39610.5%] NanoString Technologies[17224.7%] Neptune Wellness[14100%]
Achillion [10033.3%] Nymox [8258.5%] Epizyme [5739.5%]
Portola [4717.6%] Strongbridge Biopharma[3417.5%]
View complete list of Biotech stocks by weekly performance

Unfortunately not all Biotech stocks have done well this year. Investors of these stocks hope they have seen the worst and hope that these stocks are set to bounce back. The bearish stocks in this index year to date (YTD) are
Vaxxinity [-100%] Petros [-100%] Translate Bio[-95%]
Palatin Technologies[-93%] Syros [-91%] Pliant [-89%]
Affimed N.V[-87%] MoonLake Immuno[-86%] Unity nology[-86%]
Sarepta [-82%] Kala Bio[-80%] IGM [-80%]
.
Investors can get enhanced performance by riding the current stock trends. Using complex algorithms, 12Stocks.com has come up with market intelligence scores (on 0-bearish to 100-bullish scale) to identify best trending stocks. Top trending Biotech stocks are
Taysha Gene[100] DBV Technologies[100] Valneva SE[100]
Prime Medicine[100] AlloVir [100] Sarepta [100]
Monopar [100] Cara [100] Absci Corp[100]
Spruce [100] Cabaletta Bio[100] Compugen [100]
View complete list of Biotech stocks by 12Stocks.com trends

12Stocks.com: Investing in Biotech Sector using Exchange Traded Funds
The following table shows list of key exchange traded funds (ETF) that help investors track Biotech Index. For detailed view, check out our ETF Funds section of our website.

Quick View: Move mouse or cursor over ETF symbol (ticker) to view short-term Technical chart and over ETF name to view long term chart. Click on ticker or stock name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist.

12Stocks.com List of ETFs that track Biotech Index

TickerETF NameWatchlistRecent PriceMarket Intelligence ScoreChange %Week %Year-to-date %
UBIOBiotechnology  73.3480-0.0681292260.7480%
HCRFEdge Multifactor 67.142309999NA
SICKHealthcare Bear 3X 37.903609999NA
LABSBiotech Bear 1X 24.185609999NA
BTECPrincipal Healthcare Innovators 39.493001.023280%
 Market Intelligence Score (0-Bearish to 100-Bullish)
12Stocks.com: Charts, Trends, Fundamental Data and Performances of Biotech Stocks
We now take in-depth look at all Biotech stocks including charts, multi-period performances and overall trends (as measured by market intelligence score).

One can sort Biotech stocks (click link to choose) by Daily, Weekly and by Year-to-Date performances. Also, one can sort by size of the company or by market capitalization.
Select Your Default Chart Type:
Long Term Chart Daily Chart Weekly Chart 
Long Term Chart (Default)
Weekly Chart Example
Daily Chart Example
Click on stock symbol or name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist. Quick View: Move mouse or cursor over "Daily" to quickly view daily Technical stock chart and over "Weekly" to view weekly Technical stock chart.

Stock Chart of OmniAb IncOABI OmniAb Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 209.82 Millions
Recent Price: 1.60    
Market Intelligence Score: 10
Day Percent Change: -0.310559%    
Day Change: -0.03
Week Change: 1.58228%    
Year-to-date Change: -54.1%
OABI Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add OABI to Watchlist:       View:      Get Complete OABI Trend Analysis ➞

Stock Chart of Janux Therapeutics IncJANX Janux Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1441.05 Millions
Recent Price: 23.31    
Market Intelligence Score: 20
Day Percent Change: -1.64557%    
Day Change: -0.87
Week Change: 2.05779%    
Year-to-date Change: -56.2%
JANX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add JANX to Watchlist:       View:      Get Complete JANX Trend Analysis ➞

Stock Chart of Omeros CorporationOMER Omeros Corporation
Sector: Health Care
SubSector: Biotechnology
MarketCap: 283.79 Millions
Recent Price: 4.21    
Market Intelligence Score: 70
Day Percent Change: 1.71498%    
Day Change: 0.29
Week Change: 0.261905%    
Year-to-date Change: -57.2%
OMER Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add OMER to Watchlist:       View:      Get Complete OMER Trend Analysis ➞

Stock Chart of Biohaven LtdBHVN Biohaven Ltd
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1678.9 Millions
Recent Price: 15.51    
Market Intelligence Score: 100
Day Percent Change: 4.65587%    
Day Change: -0.02
Week Change: 12.8821%    
Year-to-date Change: -58.4%
BHVN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add BHVN to Watchlist:       View:      Get Complete BHVN Trend Analysis ➞

Stock Chart of Geron CorpGERN Geron Corp
Sector: Health Care
SubSector: Biotechnology
MarketCap: 893.22 Millions
Recent Price: 1.38    
Market Intelligence Score: 90
Day Percent Change: -2.48227%    
Day Change: 0.04
Week Change: 3.38346%    
Year-to-date Change: -61.8%
GERN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add GERN to Watchlist:       View:      Get Complete GERN Trend Analysis ➞

Stock Chart of Replimune Group IncREPL Replimune Group Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 494.09 Millions
Recent Price: 4.65    
Market Intelligence Score: 60
Day Percent Change: 10.4513%    
Day Change: 0.35
Week Change: 11.7788%    
Year-to-date Change: -63.0%
REPL Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add REPL to Watchlist:       View:      Get Complete REPL Trend Analysis ➞

Stock Chart of Spruce Biosciences, Inc.SPRB Spruce Biosciences, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 49487 Millions
Recent Price: 11.39    
Market Intelligence Score: 100
Day Percent Change: 12.4938%    
Day Change: -9999
Week Change: 39.3272%    
Year-to-date Change: -63.8%
SPRB Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add SPRB to Watchlist:       View:      Get Complete SPRB Trend Analysis ➞

Stock Chart of Humacyte IncHUMA Humacyte Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 226.47 Millions
Recent Price: 1.78    
Market Intelligence Score: 70
Day Percent Change: 1.42045%    
Day Change: -0.09
Week Change: 6.25%    
Year-to-date Change: -65.5%
HUMA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add HUMA to Watchlist:       View:      Get Complete HUMA Trend Analysis ➞

Stock Chart of Entrada Therapeutics IncTRDA Entrada Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 201.22 Millions
Recent Price: 5.92    
Market Intelligence Score: 25
Day Percent Change: 10.55%    
Day Change: 0.56
Week Change: 11.81%    
Year-to-date Change: -66.1%
TRDA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add TRDA to Watchlist:       View:      Get Complete TRDA Trend Analysis ➞

Stock Chart of Brainstorm Cell Therapeutics Inc.BCLI Brainstorm Cell Therapeutics Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 141.285 Millions
Recent Price: 0.65    
Market Intelligence Score: 60
Day Percent Change: 0.0310078%    
Day Change: -9999
Week Change: 1.6063%    
Year-to-date Change: -69.9%
BCLI Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add BCLI to Watchlist:       View:      Get Complete BCLI Trend Analysis ➞

Stock Chart of Avenue Therapeutics, Inc.ATXI Avenue Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 118.185 Millions
Recent Price: 0.58    
Market Intelligence Score: 70
Day Percent Change: 8.61423%    
Day Change: -9999
Week Change: 23.9846%    
Year-to-date Change: -69.9%
ATXI Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ATXI to Watchlist:       View:      Get Complete ATXI Trend Analysis ➞

Stock Chart of Iovance Biotherapeutics IncIOVA Iovance Biotherapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 901.02 Millions
Recent Price: 2.25    
Market Intelligence Score: 60
Day Percent Change: 1.80995%    
Day Change: 0.01
Week Change: 6.13208%    
Year-to-date Change: -71.1%
IOVA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add IOVA to Watchlist:       View:      Get Complete IOVA Trend Analysis ➞

Stock Chart of Aptose Biosciences Inc.APTO Aptose Biosciences Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 484.585 Millions
Recent Price: 2.01    
Market Intelligence Score: 20
Day Percent Change: 17.5439%    
Day Change: -9999
Week Change: -42.2414%    
Year-to-date Change: -71.5%
APTO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add APTO to Watchlist:       View:      Get Complete APTO Trend Analysis ➞

Stock Chart of Allakos Inc.ALLK Allakos Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 3233.55 Millions
Recent Price: 0.33    
Market Intelligence Score: 50
Day Percent Change: -0.0607349%    
Day Change: -9999
Week Change: 0.42722%    
Year-to-date Change: -73.5%
ALLK Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ALLK to Watchlist:       View:      Get Complete ALLK Trend Analysis ➞

Stock Chart of Rocket Pharmaceuticals IncRCKT Rocket Pharmaceuticals Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 353.92 Millions
Recent Price: 3.21    
Market Intelligence Score: 70
Day Percent Change: 1.42405%    
Day Change: -0.02
Week Change: -3.46386%    
Year-to-date Change: -74.8%
RCKT Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add RCKT to Watchlist:       View:      Get Complete RCKT Trend Analysis ➞

Stock Chart of IGM Biosciences, Inc.IGMS IGM Biosciences, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 2000.05 Millions
Recent Price: 1.27    
Market Intelligence Score: 10
Day Percent Change: -2.30769%    
Day Change: -9999
Week Change: -0.78125%    
Year-to-date Change: -79.5%
IGMS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add IGMS to Watchlist:       View:      Get Complete IGMS Trend Analysis ➞

Stock Chart of Kala Bio IncKALA Kala Bio Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 102.16 Millions
Recent Price: 1.54    
Market Intelligence Score: 20
Day Percent Change: 12.4252%    
Day Change: 0.16
Week Change: -91.9519%    
Year-to-date Change: -80.0%
KALA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add KALA to Watchlist:       View:      Get Complete KALA Trend Analysis ➞

Stock Chart of Sarepta Therapeutics IncSRPT Sarepta Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1828.22 Millions
Recent Price: 22.35    
Market Intelligence Score: 100
Day Percent Change: 15.6832%    
Day Change: 3.12
Week Change: 22.3987%    
Year-to-date Change: -82.0%
SRPT Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add SRPT to Watchlist:       View:      Get Complete SRPT Trend Analysis ➞

Stock Chart of Unity Biotechnology, Inc.UBX Unity Biotechnology, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 254.985 Millions
Recent Price: 0.16    
Market Intelligence Score: 0
Day Percent Change: -20.04%    
Day Change: -9999
Week Change: -58.3333%    
Year-to-date Change: -86.0%
UBX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add UBX to Watchlist:       View:      Get Complete UBX Trend Analysis ➞

Stock Chart of MoonLake ImmunotherapeuticsMLTX MoonLake Immunotherapeutics
Sector: Health Care
SubSector: Biotechnology
MarketCap: 3817.87 Millions
Recent Price: 7.46    
Market Intelligence Score: 30
Day Percent Change: 5.66572%    
Day Change: 0.03
Week Change: -85.8013%    
Year-to-date Change: -86.1%
MLTX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add MLTX to Watchlist:       View:      Get Complete MLTX Trend Analysis ➞

Stock Chart of Affimed N.V.AFMD Affimed N.V.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 161.385 Millions
Recent Price: 0.18    
Market Intelligence Score: 20
Day Percent Change: -34.9462%    
Day Change: -9999
Week Change: -73.5036%    
Year-to-date Change: -86.6%
AFMD Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add AFMD to Watchlist:       View:      Get Complete AFMD Trend Analysis ➞

Stock Chart of Pliant Therapeutics IncPLRX Pliant Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 114.18 Millions
Recent Price: 1.50    
Market Intelligence Score: 50
Day Percent Change: 3.44828%    
Day Change: 0.02
Week Change: 2.73973%    
Year-to-date Change: -88.7%
PLRX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PLRX to Watchlist:       View:      Get Complete PLRX Trend Analysis ➞

Stock Chart of Syros Pharmaceuticals, Inc.SYRS Syros Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 275.485 Millions
Recent Price: 0.02    
Market Intelligence Score: 70
Day Percent Change: 226.23%    
Day Change: -9999
Week Change: 1709.09%    
Year-to-date Change: -91.4%
SYRS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add SYRS to Watchlist:       View:      Get Complete SYRS Trend Analysis ➞

Stock Chart of Palatin Technologies, Inc.PTN Palatin Technologies, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 109.285 Millions
Recent Price: 0.09    
Market Intelligence Score: 0
Day Percent Change: -44.6471%    
Day Change: -9999
Week Change: -54.0976%    
Year-to-date Change: -92.8%
PTN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PTN to Watchlist:       View:      Get Complete PTN Trend Analysis ➞

Stock Chart of Translate Bio, Inc.TBIO Translate Bio, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 538.685 Millions
Recent Price: 0.02    
Market Intelligence Score: 20
Day Percent Change: 0%    
Day Change: -9999
Week Change: 0%    
Year-to-date Change: -94.5%
TBIO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add TBIO to Watchlist:       View:      Get Complete TBIO Trend Analysis ➞

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Click To Change The Sort Order: By Market Cap or Company Size
Performance: Year-to-date, Week and Day
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