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Best Biotech Stocks

Quick Read: Best Biotech Stocks List By Performances & Trends:
Daily, Weekly, Year-to-Date, Market Cap (Size) & Technical Trends
Best Biotech Stocks Views: Quick Browse View, Summary & Slide Show View

12Stocks.com Biotech Stocks Performances & Trends Daily
August 29, 2025 - Although long and mid term trends for Biotech sector looks good, the short term trends are deteriorating.

The overall market intelligence score is 60 (0-bearish to 100-bullish) which puts Biotech sector in short term neutral to bullish trend.

The market intelligence score from previous trading session is 100 and hence a deterioration of trend.

 Year To Date Performance: -3.05 %
 Weekly Performance: -1.2 %
 Daily Performance: -0.51 %
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Biotech Sector Trend
60 / 100
Here are the market intelligence trend scores of the most requested Biotech stocks at 12Stocks.com (click stock name for detailed review):

12Stocks.com: Investing in Biotech sector with Stocks
The following table helps investors and traders sort through current performance and trends (as measured by market intelligence score) of various stocks in the Biotech sector.

Quick View: Move mouse or cursor over stock symbol (ticker) to view short-term Technical chart and over stock name to view long term chart. Click on to add stock symbol to your watchlist and to view watchlist. Click on any ticker or stock name for detailed market intelligence report for that stock.

12Stocks.com Performance of Stocks in Biotech Sector

TickerStock NameWatchlistCategoryRecent PriceMarket Intelligence ScoreChange %YTD Change%
KMDAKamada  Biotechnology7.13101.08%19.00%
GERNGeron  Biotechnology1.41202.88%-59.60%
RLYBRallybio  Biotechnology0.5960-2.03%-38.13%
ABEOAbeona  Biotechnology6.90501.57%27.65%
MRSNMersana  Biotechnology7.634011.25%-77.31%
VORVor Biopharma Biotechnology2.0020-1.36%95.50%
NERVMinerva Neuro Biotechnology2.37705.11%8.71%
CABACabaletta Bio Biotechnology1.50301.27%-29.52%
MCRBSeres  Biotechnology18.88602.12%10.23%
PEPGPepGen  Biotechnology1.24181.63%-67.02%
BCYCBicycle  Biotechnology7.00500.85%-49.36%
CASICASI  Biotechnology2.23808.33%-12.72%
ADMAADMA Biologics Biotechnology17.2560-1.16%-0.29%
RFLRafael  Biotechnology1.5050-0.68%-10.89%
RANIRani  Biotechnology0.56203.61%-59.96%
ABOSAcumen  Biotechnology1.3930-3.55%-20.93%
SLNSilence  Biotechnology5.2002.44%-20.64%
STROSutro Biopharma Biotechnology0.9030-1.95%-53.93%
IPSCCentury  Biotechnology0.5220-0.72%-46.43%
NCNANuCana  Biotechnology3.24306.43%-98.61%
VSTMVerastem  Biotechnology9.29903.73%66.92%
SLGLSol-Gel Technologies Biotechnology21.956040.22%177.39%
NBTXNanobiotix S.A Biotechnology8.999014.15%239.28%
AVXLAnavex Life Biotechnology9.4560-1.34%-11.08%
KZRKezar Life Biotechnology3.96301.28%-41.22%
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Performance: Year-to-date, Week and Day
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Detailed Overview of Biotech Stocks
Biotech Technical Overview, Leaders & Laggards, Top Biotech ETF Funds & Detailed Biotech Stocks List, Charts, Trends & More

Biotech Sector: Technical Analysis, Trends & YTD Performance
Biotech sector, as represented by XBI, an exchange-traded fund [ETF] that holds basket of Biotech stocks (e.g, Amgen, Celgene) is down by -3.05% and is currently underperforming the overall market by -10.19% year-to-date. Below is a quick view of Technical charts and trends:

XBI Weekly Chart
Long Term Trend: Very Good
Medium Term Trend: Good

XBI Daily Chart
Short Term Trend: Not Good
Overall Trend Score: 60
YTD Performance: -3.05%
**Trend Scores & Views Are Only For Educational Purposes And Not For Investing


12Stocks.com: Top Performing Biotech Sector Stocks
Hot Biotech Stocks of 2025 We try to spot trends by analyzing the performances of various stocks or components within Biotech sector and try to find best performing stocks. The movers and shakers. The winners and losers.

The top performing Biotech sector stocks year to date are
I Mab[454%] Matinas BioPharma[241%] Nanobiotix S.A[239%]
Atai Life[230%] Precigen [225%] DBV Technologies[209%]
Galectin [201%] Sol-Gel Technologies[177%] Rigel [150%]
Gossamer Bio[140%] Lineage Cell[133%] Tango [127%]
View complete list of Biotech stocks by year-to-date performance

Now, more recently, over last week, the top performing Biotech sector stocks on the move are
Precigen [96.8%] Sol-Gel Technologies[69.2%] ALX Oncology[57.3%]
Immuneering [52.3%] Minerva Neuro[34.5%] Aligos [29.7%]
Karyopharm [29.5%] CASI [27.3%] Zentalis [26.4%]
Rocket [23.1%] Tenaya [22.5%] Nanobiotix S.A[18.8%]
View complete list of Biotech stocks by weekly performance

Unfortunately not all Biotech stocks have done well this year. Investors of these stocks hope they have seen the worst and hope that these stocks are set to bounce back. The bearish stocks in this index year to date (YTD) are
NuCana [-99%] ADiTx [-98%] Adaptimmune [-89%]
Pliant [-89%] X4 [-86%] Sarepta [-84%]
Mustang Bio[-81%] RedHill Biopharma[-79%] Acrivon [-78%]
Mersana [-77%] Aligos [-75%] Rocket [-70%]
.
Investors can get enhanced performance by riding the current stock trends. Using complex algorithms, 12Stocks.com has come up with market intelligence scores (on 0-bearish to 100-bullish scale) to identify best trending stocks. Top trending Biotech stocks are
ALX Oncology[100] Precigen [100] Fortress [100]
Design [100] Kura Oncology[100] FibroGen [100]
Madrigal [100] Nektar [100] Arcus [100]
Pharming [100] Inovio [100] BridgeBio Pharma[100]
View complete list of Biotech stocks by 12Stocks.com trends

12Stocks.com: Investing in Biotech Sector using Exchange Traded Funds
The following table shows list of key exchange traded funds (ETF) that help investors track Biotech Index. For detailed view, check out our ETF Funds section of our website.

Quick View: Move mouse or cursor over ETF symbol (ticker) to view short-term Technical chart and over ETF name to view long term chart. Click on ticker or stock name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist.

12Stocks.com List of ETFs that track Biotech Index

TickerETF NameWatchlistRecent PriceMarket Intelligence ScoreChange %Week %Year-to-date %
LABDBiotech Bear 3X 5.6650-2.55-1.37-19.84%
XBIBiotech  89.8360-0.51-1.2-3.05%
IBBBiotechnology  138.59700.730.730.89%
LABUBiotech Bull 3X 70.31702.380.61-22.08%
IYHHealthcare  57.7690-0.312.14-0.44%
IHFHealthcare Providers  47.23701.290.43-10.25%
ZBIOShort Biotech 16.71603.741.01106.72%
IXJGlobal Healthcare  87.55900.821.4-2.62%
CUREHealthcare Bull 3X 80.0080-1.026.93-12.21%
BBCBio Biotechnology Clinical 22.93602.050.29-5.46%
FBTFirst NYSE 172.0780-0.150.664.14%
PBEBiotech & Genome 68.46900.311.642.9%
BIBBiotechnology  55.82501.032.4711.53%
PTHDWA Healthcare Momentum 40.06700.670.47-1.58%
BBHBiotech  165.39700.610.531.51%
BISShort Biotech 14.2750-0.99-2.37-20.83%
BBPBio Biotechnology Products 67.71600.761.0512.25%
 Market Intelligence Score (0-Bearish to 100-Bullish)
12Stocks.com: Charts, Trends, Fundamental Data and Performances of Biotech Stocks
We now take in-depth look at all Biotech stocks including charts, multi-period performances and overall trends (as measured by market intelligence score).

One can sort Biotech stocks (click link to choose) by Daily, Weekly and by Year-to-Date performances. Also, one can sort by size of the company or by market capitalization.
Select Your Default Chart Type:
Long Term Chart Daily Chart Weekly Chart 
Long Term Chart (Default)
Weekly Chart Example
Daily Chart Example
Click on stock symbol or name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist. Quick View: Move mouse or cursor over "Daily" to quickly view daily Technical stock chart and over "Weekly" to view weekly Technical stock chart.

Stock Chart of Kamada Ltd.KMDA Kamada Ltd.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 238.685 Millions
Recent Price: 7.13    
Market Intelligence Score: 10
Day Percent Change: 1.08%    
Day Change: 0.08
Week Change: -3.49%    
Year-to-date Change: 19.0%
KMDA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add KMDA to Watchlist:       View:      Get Complete KMDA Trend Analysis ➞

Stock Chart of Geron CorporationGERN Geron Corporation
Sector: Health Care
SubSector: Biotechnology
MarketCap: 228.685 Millions
Recent Price: 1.41    
Market Intelligence Score: 20
Day Percent Change: 2.88%    
Day Change: 0.04
Week Change: -1.38%    
Year-to-date Change: -59.6%
GERN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add GERN to Watchlist:       View:      Get Complete GERN Trend Analysis ➞

Stock Chart of Rallybio CorporationRLYB Rallybio Corporation
Sector: Health Care
SubSector: Biotechnology
MarketCap: 226 Millions
Recent Price: 0.59    
Market Intelligence Score: 60
Day Percent Change: -2.03%    
Day Change: -0.01
Week Change: 8.79%    
Year-to-date Change: -38.1%
RLYB Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add RLYB to Watchlist:       View:      Get Complete RLYB Trend Analysis ➞

Stock Chart of Abeona Therapeutics Inc.ABEO Abeona Therapeutics Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 224.985 Millions
Recent Price: 6.90    
Market Intelligence Score: 50
Day Percent Change: 1.57%    
Day Change: 0.11
Week Change: -1.66%    
Year-to-date Change: 27.7%
ABEO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ABEO to Watchlist:       View:      Get Complete ABEO Trend Analysis ➞

Stock Chart of Mersana Therapeutics, Inc.MRSN Mersana Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 224.385 Millions
Recent Price: 7.63    
Market Intelligence Score: 40
Day Percent Change: 11.25%    
Day Change: 0.82
Week Change: 9.3%    
Year-to-date Change: -77.3%
MRSN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add MRSN to Watchlist:       View:      Get Complete MRSN Trend Analysis ➞

Stock Chart of Vor Biopharma Inc.VOR Vor Biopharma Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 224 Millions
Recent Price: 2.00    
Market Intelligence Score: 20
Day Percent Change: -1.36%    
Day Change: -0.03
Week Change: 9.6%    
Year-to-date Change: 95.5%
VOR Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add VOR to Watchlist:       View:      Get Complete VOR Trend Analysis ➞

Stock Chart of Minerva Neurosciences, Inc.NERV Minerva Neurosciences, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 223.385 Millions
Recent Price: 2.37    
Market Intelligence Score: 70
Day Percent Change: 5.11%    
Day Change: 0.12
Week Change: 34.54%    
Year-to-date Change: 8.7%
NERV Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add NERV to Watchlist:       View:      Get Complete NERV Trend Analysis ➞

Stock Chart of Cabaletta Bio, Inc.CABA Cabaletta Bio, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 222.085 Millions
Recent Price: 1.50    
Market Intelligence Score: 30
Day Percent Change: 1.27%    
Day Change: 0.02
Week Change: -3.03%    
Year-to-date Change: -29.5%
CABA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CABA to Watchlist:       View:      Get Complete CABA Trend Analysis ➞

Stock Chart of Seres Therapeutics, Inc.MCRB Seres Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 217.585 Millions
Recent Price: 18.88    
Market Intelligence Score: 60
Day Percent Change: 2.12%    
Day Change: 0.38
Week Change: 8.66%    
Year-to-date Change: 10.2%
MCRB Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add MCRB to Watchlist:       View:      Get Complete MCRB Trend Analysis ➞

Stock Chart of PepGen Inc.PEPG PepGen Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 216 Millions
Recent Price: 1.24    
Market Intelligence Score: 18
Day Percent Change: 1.63%    
Day Change: 0.02
Week Change: -3.1%    
Year-to-date Change: -67.0%
PEPG Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PEPG to Watchlist:       View:      Get Complete PEPG Trend Analysis ➞

Stock Chart of Bicycle Therapeutics plcBCYC Bicycle Therapeutics plc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 214.485 Millions
Recent Price: 7.00    
Market Intelligence Score: 50
Day Percent Change: 0.85%    
Day Change: 0.06
Week Change: -3.93%    
Year-to-date Change: -49.4%
BCYC Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add BCYC to Watchlist:       View:      Get Complete BCYC Trend Analysis ➞

Stock Chart of CASI Pharmaceuticals, Inc.CASI CASI Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 210.085 Millions
Recent Price: 2.23    
Market Intelligence Score: 80
Day Percent Change: 8.33%    
Day Change: 0.19
Week Change: 27.32%    
Year-to-date Change: -12.7%
CASI Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CASI to Watchlist:       View:      Get Complete CASI Trend Analysis ➞

Stock Chart of ADMA Biologics, Inc.ADMA ADMA Biologics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 204.985 Millions
Recent Price: 17.25    
Market Intelligence Score: 60
Day Percent Change: -1.16%    
Day Change: -0.2
Week Change: 0.77%    
Year-to-date Change: -0.3%
ADMA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ADMA to Watchlist:       View:      Get Complete ADMA Trend Analysis ➞

Stock Chart of Rafael Holdings, Inc.RFL Rafael Holdings, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 203.685 Millions
Recent Price: 1.50    
Market Intelligence Score: 50
Day Percent Change: -0.68%    
Day Change: -0.01
Week Change: -9.94%    
Year-to-date Change: -10.9%
RFL Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add RFL to Watchlist:       View:      Get Complete RFL Trend Analysis ➞

Stock Chart of Rani Therapeutics Holdings, Inc.RANI Rani Therapeutics Holdings, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 202 Millions
Recent Price: 0.56    
Market Intelligence Score: 20
Day Percent Change: 3.61%    
Day Change: 0.02
Week Change: -1.47%    
Year-to-date Change: -60.0%
RANI Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add RANI to Watchlist:       View:      Get Complete RANI Trend Analysis ➞

Stock Chart of Acumen Pharmaceuticals, Inc.ABOS Acumen Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 199 Millions
Recent Price: 1.39    
Market Intelligence Score: 30
Day Percent Change: -3.55%    
Day Change: -0.05
Week Change: -2.86%    
Year-to-date Change: -20.9%
ABOS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ABOS to Watchlist:       View:      Get Complete ABOS Trend Analysis ➞

Stock Chart of Silence Therapeutics plcSLN Silence Therapeutics plc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 198 Millions
Recent Price: 5.20    
Market Intelligence Score: 0
Day Percent Change: 2.44%    
Day Change: 0.13
Week Change: -3.02%    
Year-to-date Change: -20.6%
SLN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add SLN to Watchlist:       View:      Get Complete SLN Trend Analysis ➞

Stock Chart of Sutro Biopharma, Inc.STRO Sutro Biopharma, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 196.485 Millions
Recent Price: 0.90    
Market Intelligence Score: 30
Day Percent Change: -1.95%    
Day Change: -0.02
Week Change: 8.65%    
Year-to-date Change: -53.9%
STRO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add STRO to Watchlist:       View:      Get Complete STRO Trend Analysis ➞

Stock Chart of Century Therapeutics, Inc.IPSC Century Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 187 Millions
Recent Price: 0.52    
Market Intelligence Score: 20
Day Percent Change: -0.72%    
Day Change: 0
Week Change: -1.62%    
Year-to-date Change: -46.4%
IPSC Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add IPSC to Watchlist:       View:      Get Complete IPSC Trend Analysis ➞

Stock Chart of NuCana plcNCNA NuCana plc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 185.785 Millions
Recent Price: 3.24    
Market Intelligence Score: 30
Day Percent Change: 6.43%    
Day Change: 0.2
Week Change: -20.24%    
Year-to-date Change: -98.6%
NCNA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add NCNA to Watchlist:       View:      Get Complete NCNA Trend Analysis ➞

Stock Chart of Verastem, Inc.VSTM Verastem, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 184.385 Millions
Recent Price: 9.29    
Market Intelligence Score: 90
Day Percent Change: 3.73%    
Day Change: 0.31
Week Change: 11.64%    
Year-to-date Change: 66.9%
VSTM Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add VSTM to Watchlist:       View:      Get Complete VSTM Trend Analysis ➞

Stock Chart of Sol-Gel Technologies Ltd.SLGL Sol-Gel Technologies Ltd.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 183.285 Millions
Recent Price: 21.95    
Market Intelligence Score: 60
Day Percent Change: 40.22%    
Day Change: 7.4
Week Change: 69.18%    
Year-to-date Change: 177.4%
SLGL Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add SLGL to Watchlist:       View:      Get Complete SLGL Trend Analysis ➞

Stock Chart of Nanobiotix S.A.NBTX Nanobiotix S.A.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 177 Millions
Recent Price: 8.99    
Market Intelligence Score: 90
Day Percent Change: 14.15%    
Day Change: 1.21
Week Change: 18.75%    
Year-to-date Change: 239.3%
NBTX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add NBTX to Watchlist:       View:      Get Complete NBTX Trend Analysis ➞

Stock Chart of Anavex Life Sciences Corp.AVXL Anavex Life Sciences Corp.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 175.985 Millions
Recent Price: 9.45    
Market Intelligence Score: 60
Day Percent Change: -1.34%    
Day Change: -0.13
Week Change: -5.54%    
Year-to-date Change: -11.1%
AVXL Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add AVXL to Watchlist:       View:      Get Complete AVXL Trend Analysis ➞

Stock Chart of Kezar Life Sciences, Inc.KZR Kezar Life Sciences, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 174.885 Millions
Recent Price: 3.96    
Market Intelligence Score: 30
Day Percent Change: 1.28%    
Day Change: 0.05
Week Change: -0.75%    
Year-to-date Change: -41.2%
KZR Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add KZR to Watchlist:       View:      Get Complete KZR Trend Analysis ➞

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Performance: Year-to-date, Week and Day
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