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Best Biotech Stocks


Quick Read: Best Biotech Stocks List By Performances & Trends: Daily, Weekly, Year-to-Date, Market Cap (Size) & Technical Trends
Best Biotech Stocks Views: Quick Browse View, Summary & Slide Show View

12Stocks.com: Investing in Biotech sector with Stocks

The following table helps investors and traders sort through current performance and trends (as measured by market intelligence score) of various stocks in the Biotech sector.

Quick View: Move mouse or cursor over stock symbol (ticker) to view short-term Technical chart and over stock name to view long term chart. Click on to add stock symbol to your watchlist and to view watchlist. Click on any ticker or stock name for detailed market intelligence report for that stock.

12Stocks.com Performance of Stocks in Biotech Sector

Ticker Stock Name Watchlist Category Recent Price Market Intelligence Score Change % YTD Change%
NUVL Nuvalent Biotechnology 74.11 46 2.59% -5.33%
SNDX Syndax Biotechnology 12.48 73 1.48% -5.60%
VKTX Viking Biotechnology 37.89 66 0.47% -5.84%
ALKS Alkermes Biotechnology 26.71 20 0.02% -7.13%
NTLA Intellia Biotechnology 10.79 46 3.19% -7.46%
ACLX Arcellx Biotechnology 70.50 56 5.00% -8.07%
NBIX Neurocrine Biotechnology 125.01 46 0.27% -8.42%
IRON Disc Medicine Biotechnology 58.03 66 1.05% -8.47%
IMNM Immunome Biotechnology 9.69 73 -1.34% -8.76%
VRTX Vertex Biotechnology 366.54 10 0.08% -8.98%
JAZZ Jazz Biotechnology 111.30 49 -0.44% -9.62%
TGTX TG Biotechnology 26.71 10 153.47% -11.26%
KRYS Krystal Biotechnology 138.66 36 2.32% -11.49%
VNDA Vanda Biotechnology 4.20 10 3.41% -12.32%
ARWR Arrowhead Biotechnology 16.42 46 -9.86% -12.66%
BMRN BioMarin Biotechnology 57.33 73 -0.04% -12.78%
KROS Keros Biotechnology 13.73 56 -1.62% -13.27%
NUVB Nuvation Bio Biotechnology 2.30 66 4.35% -13.53%
TARS Tarsus Biotechnology 47.85 10 -0.39% -13.58%
HRTX Heron Biotechnology 1.32 20 16.77% -13.73%
UTHR United Biotechnology 301.50 47 0.62% -14.55%
BIIB Biogen Biotechnology 130.67 56 -25.22% -14.55%
OPK OPKO Health Biotechnology 1.25 20 -0.31% -14.97%
ESPR Esperion Biotechnology 1.87 74 2.91% -15.00%
AURA Aura Biotechnology 6.80 46 1.74% -17.27%
To view more stocks, click on Next / Previous arrows or select different range:
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Performance: Year-to-date, Week and Day

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Detailed Overview of Biotech Stocks
Biotech Technical Overview , Leaders & Laggards, Top Biotech ETF Funds & Detailed Biotech Stocks List, Charts, Trends & More

Biotech Sector: Technical Analysis, Trends & YTD Performance

Biotech sector, as represented by XBI, an exchange-traded fund [ETF] that holds basket of Biotech stocks (e.g, Amgen, Celgene) is down by % and is currently underperforming the overall market by -8.39% year-to-date. Below is a quick view of Technical charts and trends:

Weekly Chart

Daily Chart

Overall Trend Score:

YTD Performance: %

**Trend Scores & Views Are Only For Educational Purposes And Not For Investing

12Stocks.com: Top Performing Biotech Sector Stocks

Hot Biotech Stocks of 2025 We try to spot trends by analyzing the performances of various stocks or components within Biotech sector and try to find best performing stocks. The movers and shakers. The winners and losers.

The top performing Biotech sector stocks year to date are
Lyra [3146%] Nektar [2380%] Lyell Immunopharma[1616%]
Verrica [807%] RAPT [521%] Mersana [341%]
Generation Bio[287%] Galectin [222%] Tango [114%]
Adaptive nologies[104%] X4 [103%] Lineage Cell[96%]
View complete list of Biotech stocks by year-to-date performance

Now, more recently, over last week, the top performing Biotech sector stocks on the move are

Y-mAbs [87.9%] Alector [48.3%] Rigel [44.7%]
SIGA Technologies[38.7%] Esperion [33.6%] ALX Oncology[30.6%]
Avidity [28.9%] Novavax [27.6%] ANI [27.5%]
Syndax [25.1%] Ardelyx [20.3%] Puma nology[20.2%]
View complete list of Biotech stocks by weekly performance

Unfortunately not all Biotech stocks have done well this year. Investors of these stocks hope they have seen the worst and hope that these stocks are set to bounce back. The bearish stocks in this index year to date (YTD) are
Pliant [-87%] Sarepta [-85%] Acrivon [-79%]
IGM [-79%] Rocket [-77%] PepGen [-72%]
Iovance Bio[-71%] Entrada [-70%] Xencor [-69%]
Arvinas [-67%] Geron [-64%] Vaxcyte [-63%]
.

Investors can get enhanced performance by riding the current stock trends. Using complex algorithms, 12Stocks.com has come up with market intelligence scores (on 0-bearish to 100-bullish scale) to identify best trending stocks. Top trending Biotech stocks are
Precigen [78] Greenwich Life[78] Arcutis Bio[74]
Mersana [74] MacroGenics [74] Esperion [74]
yte [74] ALX Oncology[74] Verrica [74]
Summit [73] XOMA [73] Wave Life[73]
View complete list of Biotech stocks by 12Stocks.com trends

12Stocks.com: Investing in Biotech Sector using Exchange Traded Funds

The following table shows list of key exchange traded funds (ETF) that help investors track Biotech Index. For detailed view, check out our ETF Funds section of our website.

Quick View: Move mouse or cursor over ETF symbol (ticker) to view short-term Technical chart and over ETF name to view long term chart. Click on ticker or stock name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist.

12Stocks.com List of ETFs that track Biotech Index

Ticker ETF Name Watchlist Recent Price Market Intelligence Score Change % Week % Year-to-date %
IBB Biotechnology 132.04 66 16.19 -0.75 -0.04%
IHF Healthcare Providers 42.62 20 1.48 4.44 -11.01%
CURE Healthcare Bull 3X 69.31 33 33.21 -2.7 -24.66%
IXJ Global Healthcare 83.35 28 0.87 -0.26 -3.05%
ZBIO Short Biotech 14.63 17 0 -5.06 78.63%
BBH Biotech 159.34 69 13.23 -1.99 1.51%
BIB Biotechnology 50.80 81 2.26 -0.43 0.52%
BIS Short Biotech 15.73 18 -1.9 0.19 -12.85%
Market Intelligence Score (0-Bearish to 100-Bullish)

12Stocks.com: Charts, Trends, Fundamental Data and Performances of Biotech Stocks

We now take in-depth look at all Biotech stocks including charts, multi-period performances and overall trends (as measured by market intelligence score).

One can sort Biotech stocks (click link to choose) by Daily, Weekly and by Year-to-Date performances. Also, one can sort by size of the company or by market capitalization.

Select Your Default Chart Type:
Long Term Chart Daily Chart Weekly Chart
Long Term Chart (Default)
Weekly Chart Example
Daily Chart Example
Click on stock symbol or name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist. Quick View: Move mouse or cursor over "Daily" to quickly view daily Technical stock chart and over "Weekly" to view weekly Technical stock chart.

NUVL Nuvalent, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 2400 Millions
Recent Price: 74.11
Market Intelligence Score: 46
Day Percent Change: 2.59%
Day Change: 2.15
Week Change: -4.69%
Year-to-date Change: -5.3%
NUVL Links: Profile News Message Board
Charts:- Daily , Weekly
Add NUVL to Watchlist:       View:      Get Complete NUVL Trend Analysis ➞

SNDX Syndax Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 365.985 Millions
Recent Price: 12.48
Market Intelligence Score: 73
Day Percent Change: 1.48%
Day Change: 0.3
Week Change: 25.05%
Year-to-date Change: -5.6%
SNDX Links: Profile News Message Board
Charts:- Daily , Weekly
Add SNDX to Watchlist:       View:      Get Complete SNDX Trend Analysis ➞

VKTX Viking Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 388.585 Millions
Recent Price: 37.89
Market Intelligence Score: 66
Day Percent Change: 0.47%
Day Change: 0.3
Week Change: 15.94%
Year-to-date Change: -5.8%
VKTX Links: Profile News Message Board
Charts:- Daily , Weekly
Add VKTX to Watchlist:       View:      Get Complete VKTX Trend Analysis ➞

ALKS Alkermes plc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 2311.95 Millions
Recent Price: 26.71
Market Intelligence Score: 20
Day Percent Change: 0.02%
Day Change: 0
Week Change: 0.6%
Year-to-date Change: -7.1%
ALKS Links: Profile News Message Board
Charts:- Daily , Weekly
Add ALKS to Watchlist:       View:      Get Complete ALKS Trend Analysis ➞

NTLA Intellia Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 707.185 Millions
Recent Price: 10.79
Market Intelligence Score: 46
Day Percent Change: 3.19%
Day Change: 0.73
Week Change: -6.09%
Year-to-date Change: -7.5%
NTLA Links: Profile News Message Board
Charts:- Daily , Weekly
Add NTLA to Watchlist:       View:      Get Complete NTLA Trend Analysis ➞

ACLX Arcellx, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1530 Millions
Recent Price: 70.50
Market Intelligence Score: 56
Day Percent Change: 5%
Day Change: 3.3
Week Change: -0.9%
Year-to-date Change: -8.1%
ACLX Links: Profile News Message Board
Charts:- Daily , Weekly
Add ACLX to Watchlist:       View:      Get Complete ACLX Trend Analysis ➞

NBIX Neurocrine Biosciences, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 7897.85 Millions
Recent Price: 125.01
Market Intelligence Score: 46
Day Percent Change: 0.27%
Day Change: 0.41
Week Change: -3.03%
Year-to-date Change: -8.4%
NBIX Links: Profile News Message Board
Charts:- Daily , Weekly
Add NBIX to Watchlist:       View:      Get Complete NBIX Trend Analysis ➞

IRON Disc Medicine Opco Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1100 Millions
Recent Price: 58.03
Market Intelligence Score: 66
Day Percent Change: 1.05%
Day Change: 0.51
Week Change: -1.59%
Year-to-date Change: -8.5%
IRON Links: Profile News Message Board
Charts:- Daily , Weekly
Add IRON to Watchlist:       View:      Get Complete IRON Trend Analysis ➞

IMNM Immunome, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 12487 Millions
Recent Price: 9.69
Market Intelligence Score: 73
Day Percent Change: -1.34%
Day Change: -0.21
Week Change: -8.5%
Year-to-date Change: -8.8%
IMNM Links: Profile News Message Board
Charts:- Daily , Weekly
Add IMNM to Watchlist:       View:      Get Complete IMNM Trend Analysis ➞

VRTX Vertex Pharmaceuticals Incorporated
Sector: Health Care
SubSector: Biotechnology
MarketCap: 57669.6 Millions
Recent Price: 366.54
Market Intelligence Score: 10
Day Percent Change: 0.08%
Day Change: 0.37
Week Change: -20.68%
Year-to-date Change: -9.0%
VRTX Links: Profile News Message Board
Charts:- Daily , Weekly
Add VRTX to Watchlist:       View:      Get Complete VRTX Trend Analysis ➞

JAZZ Jazz Pharmaceuticals plc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 5576.05 Millions
Recent Price: 111.30
Market Intelligence Score: 49
Day Percent Change: -0.44%
Day Change: -0.5
Week Change: -3.65%
Year-to-date Change: -9.6%
JAZZ Links: Profile News Message Board
Charts:- Daily , Weekly
Add JAZZ to Watchlist:       View:      Get Complete JAZZ Trend Analysis ➞

TGTX TG Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1022.85 Millions
Recent Price: 26.71
Market Intelligence Score: 10
Day Percent Change: 153.47%
Day Change: 14.81
Week Change: -23.73%
Year-to-date Change: -11.3%
TGTX Links: Profile News Message Board
Charts:- Daily , Weekly
Add TGTX to Watchlist:       View:      Get Complete TGTX Trend Analysis ➞

KRYS Krystal Biotech, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 874.085 Millions
Recent Price: 138.66
Market Intelligence Score: 36
Day Percent Change: 2.32%
Day Change: 4.57
Week Change: -11.67%
Year-to-date Change: -11.5%
KRYS Links: Profile News Message Board
Charts:- Daily , Weekly
Add KRYS to Watchlist:       View:      Get Complete KRYS Trend Analysis ➞

VNDA Vanda Pharmaceuticals Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 464.585 Millions
Recent Price: 4.20
Market Intelligence Score: 10
Day Percent Change: 3.41%
Day Change: 0.18
Week Change: 0.24%
Year-to-date Change: -12.3%
VNDA Links: Profile News Message Board
Charts:- Daily , Weekly
Add VNDA to Watchlist:       View:      Get Complete VNDA Trend Analysis ➞

ARWR Arrowhead Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 3226.15 Millions
Recent Price: 16.42
Market Intelligence Score: 46
Day Percent Change: -9.86%
Day Change: -2.71
Week Change: 3.08%
Year-to-date Change: -12.7%
ARWR Links: Profile News Message Board
Charts:- Daily , Weekly
Add ARWR to Watchlist:       View:      Get Complete ARWR Trend Analysis ➞

BMRN BioMarin Pharmaceutical Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 14887.5 Millions
Recent Price: 57.33
Market Intelligence Score: 73
Day Percent Change: -0.04%
Day Change: -0.04
Week Change: -1.39%
Year-to-date Change: -12.8%
BMRN Links: Profile News Message Board
Charts:- Daily , Weekly
Add BMRN to Watchlist:       View:      Get Complete BMRN Trend Analysis ➞

KROS Keros Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 17887 Millions
Recent Price: 13.73
Market Intelligence Score: 56
Day Percent Change: -1.62%
Day Change: -0.75
Week Change: -4.12%
Year-to-date Change: -13.3%
KROS Links: Profile News Message Board
Charts:- Daily , Weekly
Add KROS to Watchlist:       View:      Get Complete KROS Trend Analysis ➞

NUVB Nuvation Bio Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 381 Millions
Recent Price: 2.30
Market Intelligence Score: 66
Day Percent Change: 4.35%
Day Change: 0.12
Week Change: 3.14%
Year-to-date Change: -13.5%
NUVB Links: Profile News Message Board
Charts:- Daily , Weekly
Add NUVB to Watchlist:       View:      Get Complete NUVB Trend Analysis ➞

TARS Tarsus Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 74487 Millions
Recent Price: 47.85
Market Intelligence Score: 10
Day Percent Change: -0.39%
Day Change: -0.1
Week Change: 17.25%
Year-to-date Change: -13.6%
TARS Links: Profile News Message Board
Charts:- Daily , Weekly
Add TARS to Watchlist:       View:      Get Complete TARS Trend Analysis ➞

HRTX Heron Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1172.75 Millions
Recent Price: 1.32
Market Intelligence Score: 20
Day Percent Change: 16.77%
Day Change: 0.28
Week Change: -21.89%
Year-to-date Change: -13.7%
HRTX Links: Profile News Message Board
Charts:- Daily , Weekly
Add HRTX to Watchlist:       View:      Get Complete HRTX Trend Analysis ➞

UTHR United Therapeutics Corporation
Sector: Health Care
SubSector: Biotechnology
MarketCap: 3980.75 Millions
Recent Price: 301.50
Market Intelligence Score: 47
Day Percent Change: 0.62%
Day Change: 2.15
Week Change: 2.45%
Year-to-date Change: -14.6%
UTHR Links: Profile News Message Board
Charts:- Daily , Weekly
Add UTHR to Watchlist:       View:      Get Complete UTHR Trend Analysis ➞

BIIB Biogen Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 53102.6 Millions
Recent Price: 130.67
Market Intelligence Score: 56
Day Percent Change: -25.22%
Day Change: -69.14
Week Change: -0.97%
Year-to-date Change: -14.6%
BIIB Links: Profile News Message Board
Charts:- Daily , Weekly
Add BIIB to Watchlist:       View:      Get Complete BIIB Trend Analysis ➞

OPK OPKO Health, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1116.05 Millions
Recent Price: 1.25
Market Intelligence Score: 20
Day Percent Change: -0.31%
Day Change: 0
Week Change: 5.04%
Year-to-date Change: -15.0%
OPK Links: Profile News Message Board
Charts:- Daily , Weekly
Add OPK to Watchlist:       View:      Get Complete OPK Trend Analysis ➞

ESPR Esperion Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1153.55 Millions
Recent Price: 1.87
Market Intelligence Score: 74
Day Percent Change: 2.91%
Day Change: 0.05
Week Change: 33.57%
Year-to-date Change: -15.0%
ESPR Links: Profile News Message Board
Charts:- Daily , Weekly
Add ESPR to Watchlist:       View:      Get Complete ESPR Trend Analysis ➞

AURA Aura Biosciences, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 469 Millions
Recent Price: 6.80
Market Intelligence Score: 46
Day Percent Change: 1.74%
Day Change: 0.13
Week Change: 0.89%
Year-to-date Change: -17.3%
AURA Links: Profile News Message Board
Charts:- Daily , Weekly
Add AURA to Watchlist:       View:      Get Complete AURA Trend Analysis ➞

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Biotech Stocks With Best Up Trends [0-bearish to 100-bullish]:
Precigen [78], Greenwich Life[78], Arcutis Bio[74], Mersana [74], MacroGenics [74], Esperion [74], yte [74], ALX Oncology[74], Verrica [74], Summit [73], XOMA [73]

Best Biotech Stocks Year-to-Date:
Lyra [3146.12%], Nektar [2379.57%], Lyell Immunopharma[1615.63%], Verrica [807.14%], RAPT [520.89%], Mersana [340.56%], Generation Bio[286.79%], Galectin [221.71%], Tango [113.92%], Adaptive nologies[103.5%], X4 [103%]

Best Biotech Stocks This Week:
Y-mAbs [87.86%], Alector [48.28%], Rigel [44.68%], SIGA Technologies[38.7%], Esperion [33.57%], ALX Oncology[30.63%], Avidity [28.87%], Novavax [27.59%], ANI [27.45%], Syndax [25.05%], Ardelyx [20.32%]

Best Biotech Stocks Daily:
Corbus [827.02%], Summit [647.43%], Applied [270.13%], Crinetics [209.71%], TG [153.47%], Arbutus Biopharma[91.63%], XOMA [80.51%], Cytokinetics [79.41%], Iovance Bio[66.25%], Novavax [65.84%], Mirum [64.05%]

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