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Best Biotech Stocks

Quick Read: Best Biotech Stocks List By Performances & Trends:
Daily, Weekly, Year-to-Date, Market Cap (Size) & Technical Trends
Best Biotech Stocks Views: Quick Browse View, Summary & Slide Show View

12Stocks.com Biotech Stocks Performances & Trends Daily
October 3, 2025 - All trends (long term, mid-term and short term) for Biotech sector looks good.

The overall market intelligence score is 100 (0-bearish to 100-bullish) which puts Biotech sector in short term bullish trend.

The market intelligence score from previous trading session is 90 and an improvement of trend continues.

 Year To Date Performance: 12.1001 %
 Weekly Performance: 5.2853 %
 Daily Performance: 1.18355 %
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Biotech Sector Trend
100 / 100
Here are the market intelligence trend scores of the most requested Biotech stocks at 12Stocks.com (click stock name for detailed review):

12Stocks.com: Investing in Biotech sector with Stocks
The following table helps investors and traders sort through current performance and trends (as measured by market intelligence score) of various stocks in the Biotech sector.

Quick View: Move mouse or cursor over stock symbol (ticker) to view short-term Technical chart and over stock name to view long term chart. Click on to add stock symbol to your watchlist and to view watchlist. Click on any ticker or stock name for detailed market intelligence report for that stock.

12Stocks.com Performance of Stocks in Biotech Sector

TickerStock NameWatchlistCategoryRecent PriceMarket Intelligence ScoreChange %YTD Change%
XONIntrexon  Biotechnology73.48100.52%0.00%
PPHMPeregrine  Biotechnology4.22100.00%0.00%
PBMDPrima Biomed Biotechnology1.71100.00%0.00%
AKAOAchaogen  Biotechnology2.21100.00%0.00%
APTXAptinyx  Biotechnology0.15100.00%0.00%
RUBYRubius  Biotechnology0.17100.00%0.00%
ODTOdonate  Biotechnology12900.00100.00%0.00%
MGTAMagenta  Biotechnology0.70100.00%0.00%
GRTSGritstone Oncology Biotechnology0.02100.00%0.00%
MLNDMillendo  Biotechnology1.06100.00%0.00%
ZEALZealand Pharma Biotechnology17.59100.00%0.00%
KITEKite Pharma Biotechnology22.4610-0.09%0.00%
CBPOChina Biologic Biotechnology8.4710-0.24%0.00%
OABIOmniAb  Biotechnology1.6010-0.31%-54.14%
TSROTesaro  Biotechnology115.6010-0.66%0.00%
HRMYHarmony  Biotechnology26.7410-0.67%-23.23%
EGLTEgalet  Biotechnology17.1610-0.98%0.00%
OPHTOphthotech  Biotechnology4.7610-1.04%0.00%
LEGNLegend  Biotechnology32.2610-1.22%-7.11%
AVROAVROBIO  Biotechnology1.4010-1.41%0.00%
IPHAInnate Pharma Biotechnology1.7810-2.20%-4.81%
IGMSIGM  Biotechnology1.2710-2.31%-79.55%
KALVKalVista  Biotechnology11.7510-2.49%32.62%
AMAGAMAG  Biotechnology1.1710-2.50%0.00%
OSIROsiris  Biotechnology0.6210-3.13%0.00%
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Performance: Year-to-date, Week and Day
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Detailed Overview of Biotech Stocks
Biotech Technical Overview, Leaders & Laggards, Top Biotech ETF Funds & Detailed Biotech Stocks List, Charts, Trends & More

Biotech Sector: Technical Analysis, Trends & YTD Performance
Biotech sector, as represented by XBI, an exchange-traded fund [ETF] that holds basket of Biotech stocks (e.g, Amgen, Celgene) is up by 12.1001% and is currently underperforming the overall market by -2.6578% year-to-date. Below is a quick view of Technical charts and trends:

XBI Weekly Chart
Long Term Trend: Very Good
Medium Term Trend: Very Good

XBI Daily Chart
Short Term Trend: Very Good
Overall Trend Score: 100
YTD Performance: 12.1001%
**Trend Scores & Views Are Only For Educational Purposes And Not For Investing


12Stocks.com: Top Performing Biotech Sector Stocks
Hot Biotech Stocks of 2025 We try to spot trends by analyzing the performances of various stocks or components within Biotech sector and try to find best performing stocks. The movers and shakers. The winners and losers.

The top performing Biotech sector stocks year to date are
Vor Biopharma[3175%] Nanobiotix ADR[581%] I-Mab ADR[358%]
Monopar [337%] Nektar [320%] DBV Technologies[277%]
Celcuity [276%] Galectin [263%] Cidara [261%]
Lineage Cell[234%] ATAI Life[221%]
View complete list of Biotech stocks by year-to-date performance

Now, more recently, over last week, the top performing Biotech sector stocks on the move are
Athersys [193287%] VBI Vaccines[86898.5%] ContraFect [47677.8%]
Clovis Oncology[39610.5%] NanoString Technologies[17224.7%] Neptune Wellness[14100%]
Achillion [10033.3%] Nymox [8258.5%] Epizyme [5739.5%]
Portola [4717.6%] Strongbridge Biopharma[3417.5%]
View complete list of Biotech stocks by weekly performance

Unfortunately not all Biotech stocks have done well this year. Investors of these stocks hope they have seen the worst and hope that these stocks are set to bounce back. The bearish stocks in this index year to date (YTD) are
Vaxxinity [-100%] Petros [-100%] Translate Bio[-95%]
Palatin Technologies[-93%] Syros [-91%] Pliant [-89%]
Affimed N.V[-87%] MoonLake Immuno[-86%] Unity nology[-86%]
Sarepta [-82%] Kala Bio[-80%] IGM [-80%]
.
Investors can get enhanced performance by riding the current stock trends. Using complex algorithms, 12Stocks.com has come up with market intelligence scores (on 0-bearish to 100-bullish scale) to identify best trending stocks. Top trending Biotech stocks are
Taysha Gene[100] DBV Technologies[100] Valneva SE[100]
Prime Medicine[100] AlloVir [100] Sarepta [100]
Monopar [100] Cara [100] Absci Corp[100]
Spruce [100] Cabaletta Bio[100] Compugen [100]
View complete list of Biotech stocks by 12Stocks.com trends

12Stocks.com: Investing in Biotech Sector using Exchange Traded Funds
The following table shows list of key exchange traded funds (ETF) that help investors track Biotech Index. For detailed view, check out our ETF Funds section of our website.

Quick View: Move mouse or cursor over ETF symbol (ticker) to view short-term Technical chart and over ETF name to view long term chart. Click on ticker or stock name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist.

12Stocks.com List of ETFs that track Biotech Index

TickerETF NameWatchlistRecent PriceMarket Intelligence ScoreChange %Week %Year-to-date %
UBIOBiotechnology  73.3480-0.0681292260.7480%
HCRFEdge Multifactor 67.142309999NA
SICKHealthcare Bear 3X 37.903609999NA
LABSBiotech Bear 1X 24.185609999NA
BTECPrincipal Healthcare Innovators 39.493001.023280%
 Market Intelligence Score (0-Bearish to 100-Bullish)
12Stocks.com: Charts, Trends, Fundamental Data and Performances of Biotech Stocks
We now take in-depth look at all Biotech stocks including charts, multi-period performances and overall trends (as measured by market intelligence score).

One can sort Biotech stocks (click link to choose) by Daily, Weekly and by Year-to-Date performances. Also, one can sort by size of the company or by market capitalization.
Select Your Default Chart Type:
Long Term Chart Daily Chart Weekly Chart 
Long Term Chart (Default)
Weekly Chart Example
Daily Chart Example
Click on stock symbol or name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist. Quick View: Move mouse or cursor over "Daily" to quickly view daily Technical stock chart and over "Weekly" to view weekly Technical stock chart.

Stock Chart of Intrexon CorporationXON Intrexon Corporation
Sector: Health Care
SubSector: Biotechnology
MarketCap: 2509.15 Millions
Recent Price: 73.48    
Market Intelligence Score: 10
Day Percent Change: 0.519836%    
Day Change: -9999
Week Change: -57.9465%    
Year-to-date Change: 0.0%
XON Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add XON to Watchlist:       View:      Get Complete XON Trend Analysis ➞

Stock Chart of Peregrine Pharmaceuticals, Inc.PPHM Peregrine Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 168.51 Millions
Recent Price: 4.22    
Market Intelligence Score: 10
Day Percent Change: 0%    
Day Change: -9999
Week Change: 0%    
Year-to-date Change: 0.0%
PPHM Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PPHM to Watchlist:       View:      Get Complete PPHM Trend Analysis ➞

Stock Chart of Prima Biomed Ltd.PBMD Prima Biomed Ltd.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 160.51 Millions
Recent Price: 1.71    
Market Intelligence Score: 10
Day Percent Change: 0%    
Day Change: -9999
Week Change: 0%    
Year-to-date Change: 0.0%
PBMD Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PBMD to Watchlist:       View:      Get Complete PBMD Trend Analysis ➞

Stock Chart of Achaogen, Inc.AKAO Achaogen, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 751.74 Millions
Recent Price: 2.21    
Market Intelligence Score: 10
Day Percent Change: 0%    
Day Change: -9999
Week Change: -78.8921%    
Year-to-date Change: 0.0%
AKAO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add AKAO to Watchlist:       View:      Get Complete AKAO Trend Analysis ➞

Stock Chart of Aptinyx Inc.APTX Aptinyx Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 109.285 Millions
Recent Price: 0.15    
Market Intelligence Score: 10
Day Percent Change: 0%    
Day Change: -9999
Week Change: 0%    
Year-to-date Change: 0.0%
APTX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add APTX to Watchlist:       View:      Get Complete APTX Trend Analysis ➞

Stock Chart of Rubius Therapeutics, Inc.RUBY Rubius Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 530.585 Millions
Recent Price: 0.17    
Market Intelligence Score: 10
Day Percent Change: 0%    
Day Change: -9999
Week Change: 0%    
Year-to-date Change: 0.0%
RUBY Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add RUBY to Watchlist:       View:      Get Complete RUBY Trend Analysis ➞

Stock Chart of Odonate Therapeutics, Inc.ODT Odonate Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 684.485 Millions
Recent Price: 12900.00    
Market Intelligence Score: 10
Day Percent Change: 0%    
Day Change: -9999
Week Change: -5.14706%    
Year-to-date Change: 0.0%
ODT Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ODT to Watchlist:       View:      Get Complete ODT Trend Analysis ➞

Stock Chart of Magenta Therapeutics, Inc.MGTA Magenta Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 267.485 Millions
Recent Price: 0.70    
Market Intelligence Score: 10
Day Percent Change: 0%    
Day Change: -9999
Week Change: -93.75%    
Year-to-date Change: 0.0%
MGTA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add MGTA to Watchlist:       View:      Get Complete MGTA Trend Analysis ➞

Stock Chart of Gritstone Oncology, Inc.GRTS Gritstone Oncology, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 240.085 Millions
Recent Price: 0.02    
Market Intelligence Score: 10
Day Percent Change: 0%    
Day Change: -9999
Week Change: -7.6555%    
Year-to-date Change: 0.0%
GRTS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add GRTS to Watchlist:       View:      Get Complete GRTS Trend Analysis ➞

Stock Chart of Millendo Therapeutics, Inc.MLND Millendo Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 103.685 Millions
Recent Price: 1.06    
Market Intelligence Score: 10
Day Percent Change: 0%    
Day Change: -9999
Week Change: 0%    
Year-to-date Change: 0.0%
MLND Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add MLND to Watchlist:       View:      Get Complete MLND Trend Analysis ➞

Stock Chart of Zealand Pharma A/SZEAL Zealand Pharma A/S
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1025.75 Millions
Recent Price: 17.59    
Market Intelligence Score: 10
Day Percent Change: 0%    
Day Change: -9999
Week Change: 0%    
Year-to-date Change: 0.0%
ZEAL Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ZEAL to Watchlist:       View:      Get Complete ZEAL Trend Analysis ➞

Stock Chart of Kite Pharma, Inc.KITE Kite Pharma, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 4462.1 Millions
Recent Price: 22.46    
Market Intelligence Score: 10
Day Percent Change: -0.088968%    
Day Change: -9999
Week Change: -32.5323%    
Year-to-date Change: 0.0%
KITE Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add KITE to Watchlist:       View:      Get Complete KITE Trend Analysis ➞

Stock Chart of China Biologic Products Holdings, Inc.CBPO China Biologic Products Holdings, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 4360.65 Millions
Recent Price: 8.47    
Market Intelligence Score: 10
Day Percent Change: -0.235571%    
Day Change: -9999
Week Change: -71.9536%    
Year-to-date Change: 0.0%
CBPO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CBPO to Watchlist:       View:      Get Complete CBPO Trend Analysis ➞

Stock Chart of OmniAb IncOABI OmniAb Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 209.82 Millions
Recent Price: 1.60    
Market Intelligence Score: 10
Day Percent Change: -0.310559%    
Day Change: -0.03
Week Change: 1.58228%    
Year-to-date Change: -54.1%
OABI Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add OABI to Watchlist:       View:      Get Complete OABI Trend Analysis ➞

Stock Chart of Tesaro, Inc.TSRO Tesaro, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 8179.76 Millions
Recent Price: 115.60    
Market Intelligence Score: 10
Day Percent Change: -0.661683%    
Day Change: -9999
Week Change: -34.1873%    
Year-to-date Change: 0.0%
TSRO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add TSRO to Watchlist:       View:      Get Complete TSRO Trend Analysis ➞

Stock Chart of Harmony Biosciences Holdings IncHRMY Harmony Biosciences Holdings Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 2070.6 Millions
Recent Price: 26.74    
Market Intelligence Score: 10
Day Percent Change: -0.668648%    
Day Change: 0.66
Week Change: -0.0747384%    
Year-to-date Change: -23.2%
HRMY Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add HRMY to Watchlist:       View:      Get Complete HRMY Trend Analysis ➞

Stock Chart of Egalet CorporationEGLT Egalet Corporation
Sector: Health Care
SubSector: Biotechnology
MarketCap: 118.55 Millions
Recent Price: 17.16    
Market Intelligence Score: 10
Day Percent Change: -0.980958%    
Day Change: -9999
Week Change: -5.61056%    
Year-to-date Change: 0.0%
EGLT Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add EGLT to Watchlist:       View:      Get Complete EGLT Trend Analysis ➞

Stock Chart of Ophthotech CorporationOPHT Ophthotech Corporation
Sector: Health Care
SubSector: Biotechnology
MarketCap: 124.59 Millions
Recent Price: 4.76    
Market Intelligence Score: 10
Day Percent Change: -1.0395%    
Day Change: -9999
Week Change: -76.5863%    
Year-to-date Change: 0.0%
OPHT Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add OPHT to Watchlist:       View:      Get Complete OPHT Trend Analysis ➞

Stock Chart of Legend Biotech Corp ADRLEGN Legend Biotech Corp ADR
Sector: Health Care
SubSector: Biotechnology
MarketCap: 6659.29 Millions
Recent Price: 32.26    
Market Intelligence Score: 10
Day Percent Change: -1.22474%    
Day Change: -0.1
Week Change: -1.88564%    
Year-to-date Change: -7.1%
LEGN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add LEGN to Watchlist:       View:      Get Complete LEGN Trend Analysis ➞

Stock Chart of AVROBIO, Inc.AVRO AVROBIO, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 626.185 Millions
Recent Price: 1.40    
Market Intelligence Score: 10
Day Percent Change: -1.40845%    
Day Change: -9999
Week Change: -6.04027%    
Year-to-date Change: 0.0%
AVRO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add AVRO to Watchlist:       View:      Get Complete AVRO Trend Analysis ➞

Stock Chart of Innate Pharma ADRIPHA Innate Pharma ADR
Sector: Health Care
SubSector: Biotechnology
MarketCap: 188.92 Millions
Recent Price: 1.78    
Market Intelligence Score: 10
Day Percent Change: -2.1978%    
Day Change: 0
Week Change: -8.24742%    
Year-to-date Change: -4.8%
IPHA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add IPHA to Watchlist:       View:      Get Complete IPHA Trend Analysis ➞

Stock Chart of IGM Biosciences, Inc.IGMS IGM Biosciences, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 2000.05 Millions
Recent Price: 1.27    
Market Intelligence Score: 10
Day Percent Change: -2.30769%    
Day Change: -9999
Week Change: -0.78125%    
Year-to-date Change: -79.5%
IGMS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add IGMS to Watchlist:       View:      Get Complete IGMS Trend Analysis ➞

Stock Chart of KalVista Pharmaceuticals IncKALV KalVista Pharmaceuticals Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 790.27 Millions
Recent Price: 11.75    
Market Intelligence Score: 10
Day Percent Change: -2.48963%    
Day Change: 0.05
Week Change: -9.12606%    
Year-to-date Change: 32.6%
KALV Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add KALV to Watchlist:       View:      Get Complete KALV Trend Analysis ➞

Stock Chart of AMAG Pharmaceuticals, Inc.AMAG AMAG Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 217.385 Millions
Recent Price: 1.17    
Market Intelligence Score: 10
Day Percent Change: -2.5%    
Day Change: -9999
Week Change: -71.9424%    
Year-to-date Change: 0.0%
AMAG Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add AMAG to Watchlist:       View:      Get Complete AMAG Trend Analysis ➞

Stock Chart of Osiris Therapeutics, Inc.OSIR Osiris Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 103.36 Millions
Recent Price: 0.62    
Market Intelligence Score: 10
Day Percent Change: -3.125%    
Day Change: -9999
Week Change: -47.8992%    
Year-to-date Change: 0.0%
OSIR Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add OSIR to Watchlist:       View:      Get Complete OSIR Trend Analysis ➞

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Performance: Year-to-date, Week and Day
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