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Best Biotech Stocks

Quick Read: Best Biotech Stocks List By Performances & Trends:
Daily, Weekly, Year-to-Date, Market Cap (Size) & Technical Trends
Best Biotech Stocks Views: Quick Browse View, Summary & Slide Show View

12Stocks.com Biotech Stocks Performances & Trends Daily
September 18, 2025 - Although long and mid term trends for Biotech sector looks good, the short term trends are deteriorating.

The overall market intelligence score is 60 (0-bearish to 100-bullish) which puts Biotech sector in short term neutral to bullish trend.

The market intelligence score from previous trading session is 70 and a deterioration of trend continues.

 Year To Date Performance: 2.46251 %
 Weekly Performance: -1.27395 %
 Daily Performance: 0.0320034 %
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Biotech Sector Trend
60 / 100
Here are the market intelligence trend scores of the most requested Biotech stocks at 12Stocks.com (click stock name for detailed review):

12Stocks.com: Investing in Biotech sector with Stocks
The following table helps investors and traders sort through current performance and trends (as measured by market intelligence score) of various stocks in the Biotech sector.

Quick View: Move mouse or cursor over stock symbol (ticker) to view short-term Technical chart and over stock name to view long term chart. Click on to add stock symbol to your watchlist and to view watchlist. Click on any ticker or stock name for detailed market intelligence report for that stock.

12Stocks.com Performance of Stocks in Biotech Sector

TickerStock NameWatchlistCategoryRecent PriceMarket Intelligence ScoreChange %YTD Change%
VTLVital Therapies Biotechnology9.820-0.61%0.00%
BCLIBrainstorm Cell Biotechnology0.65600.03%-69.85%
AGLEAeglea Bio Biotechnology27.6060-0.29%0.00%
VBIVVBI Vaccines Biotechnology56.81700.28%0.00%
MEIPMEI Pharma Biotechnology3.073010.43%20.39%
LJPCLa Jolla Biotechnology6.22300.00%0.00%
AGENAgenus  Biotechnology4.55401.79%47.25%
MOLNMolecular Partners Biotechnology3.6320-6.68%-25.46%
CGENCompugen  Biotechnology1.3610-1.45%-17.58%
OCXOncoCyte  Biotechnology3.1650-1.25%35.62%
VXRTVaxart  Biotechnology0.3930-0.51%-46.01%
GNLXGenelux Corp Biotechnology3.91532.38%45.76%
CFRXContraFect  Biotechnology10.75901.42%0.00%
MGNXMacrogenics  Biotechnology1.53304.08%-53.64%
ZNTLZentalis  Biotechnology1.42400.00%-52.67%
SRRASierra Oncology Biotechnology14.95303.68%0.00%
OPHTOphthotech  Biotechnology4.7610-1.04%0.00%
SELBSelecta  Biotechnology2.70600.00%0.00%
TYMETyme Technologies Biotechnology0.31200.00%0.00%
OBSVObsEva SA Biotechnology0.08201.20%0.00%
PLXProtalix Bio Biotechnology1.87100-2.09%-5.08%
TARAProtara  Biotechnology3.030-1.30%-45.70%
SPROSpero  Biotechnology1.9000.00%75.93%
CRBPCorbus  Biotechnology11.6210013.15%-3.49%
ENOBEnochian  Biotechnology0.70300.00%0.00%
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Performance: Year-to-date, Week and Day
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Detailed Overview of Biotech Stocks
Biotech Technical Overview, Leaders & Laggards, Top Biotech ETF Funds & Detailed Biotech Stocks List, Charts, Trends & More

Biotech Sector: Technical Analysis, Trends & YTD Performance
Biotech sector, as represented by XBI, an exchange-traded fund [ETF] that holds basket of Biotech stocks (e.g, Amgen, Celgene) is up by 2.46251% and is currently underperforming the overall market by -10.68429% year-to-date. Below is a quick view of Technical charts and trends:

XBI Weekly Chart
Long Term Trend: Very Good
Medium Term Trend: Very Good

XBI Daily Chart
Short Term Trend: Not Good
Overall Trend Score: 60
YTD Performance: 2.46251%
**Trend Scores & Views Are Only For Educational Purposes And Not For Investing


12Stocks.com: Top Performing Biotech Sector Stocks
Hot Biotech Stocks of 2025 We try to spot trends by analyzing the performances of various stocks or components within Biotech sector and try to find best performing stocks. The movers and shakers. The winners and losers.

The top performing Biotech sector stocks year to date are
Celcuity [316%] I-Mab ADR[307%] Galectin [292%]
Immuneering Corp[265%] Nektar [254%] Precigen [254%]
Nanobiotix ADR[252%] Gossamer Bio[208%] DBV Technologies[203%]
Monopar [200%] ATAI Life[194%]
View complete list of Biotech stocks by year-to-date performance

Now, more recently, over last week, the top performing Biotech sector stocks on the move are
Athersys [193287%] VBI Vaccines[86898.5%] ContraFect [47677.8%]
Clovis Oncology[39610.5%] NanoString Technologies[17224.7%] Neptune Wellness[14100%]
Achillion [10033.3%] Nymox [8258.5%] Epizyme [5739.5%]
Portola [4717.6%] Strongbridge Biopharma[3417.5%]
View complete list of Biotech stocks by weekly performance

Unfortunately not all Biotech stocks have done well this year. Investors of these stocks hope they have seen the worst and hope that these stocks are set to bounce back. The bearish stocks in this index year to date (YTD) are
Vaxxinity [-100%] Petros [-100%] Translate Bio[-95%]
Palatin Technologies[-93%] Syros [-91%] Pliant [-88%]
Affimed N.V[-87%] Sarepta [-86%] Unity nology[-86%]
IGM [-80%] Rocket [-76%] Allakos [-73%]
.
Investors can get enhanced performance by riding the current stock trends. Using complex algorithms, 12Stocks.com has come up with market intelligence scores (on 0-bearish to 100-bullish scale) to identify best trending stocks. Top trending Biotech stocks are
AlloVir [100] Monopar [100] Cara [100]
Corbus [100] Spruce [100] Ocugen [100]
Roivant [100] Xencor [100] Oncolytics [100]
Tango [100] Arcus [100] Regeneron [100]
View complete list of Biotech stocks by 12Stocks.com trends

12Stocks.com: Investing in Biotech Sector using Exchange Traded Funds
The following table shows list of key exchange traded funds (ETF) that help investors track Biotech Index. For detailed view, check out our ETF Funds section of our website.

Quick View: Move mouse or cursor over ETF symbol (ticker) to view short-term Technical chart and over ETF name to view long term chart. Click on ticker or stock name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist.

12Stocks.com List of ETFs that track Biotech Index

TickerETF NameWatchlistRecent PriceMarket Intelligence ScoreChange %Week %Year-to-date %
UBIOBiotechnology  73.3480-0.0681292260.7480%
HCRFEdge Multifactor 67.142309999NA
SICKHealthcare Bear 3X 37.903609999NA
LABSBiotech Bear 1X 24.185609999NA
BTECPrincipal Healthcare Innovators 39.493001.023280%
 Market Intelligence Score (0-Bearish to 100-Bullish)
12Stocks.com: Charts, Trends, Fundamental Data and Performances of Biotech Stocks
We now take in-depth look at all Biotech stocks including charts, multi-period performances and overall trends (as measured by market intelligence score).

One can sort Biotech stocks (click link to choose) by Daily, Weekly and by Year-to-Date performances. Also, one can sort by size of the company or by market capitalization.
Select Your Default Chart Type:
Long Term Chart Daily Chart Weekly Chart 
Long Term Chart (Default)
Weekly Chart Example
Daily Chart Example
Click on stock symbol or name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist. Quick View: Move mouse or cursor over "Daily" to quickly view daily Technical stock chart and over "Weekly" to view weekly Technical stock chart.

Stock Chart of Vital Therapies, Inc.VTL Vital Therapies, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 142.97 Millions
Recent Price: 9.82    
Market Intelligence Score: 0
Day Percent Change: -0.607287%    
Day Change: -9999
Week Change: -51.697%    
Year-to-date Change: 0.0%
VTL Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add VTL to Watchlist:       View:      Get Complete VTL Trend Analysis ➞

Stock Chart of Brainstorm Cell Therapeutics Inc.BCLI Brainstorm Cell Therapeutics Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 141.285 Millions
Recent Price: 0.65    
Market Intelligence Score: 60
Day Percent Change: 0.0310078%    
Day Change: -9999
Week Change: 1.6063%    
Year-to-date Change: -69.9%
BCLI Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add BCLI to Watchlist:       View:      Get Complete BCLI Trend Analysis ➞

Stock Chart of Aeglea BioTherapeutics, Inc.AGLE Aeglea BioTherapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 140.085 Millions
Recent Price: 27.60    
Market Intelligence Score: 60
Day Percent Change: -0.289017%    
Day Change: -9999
Week Change: 1.7324%    
Year-to-date Change: 0.0%
AGLE Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add AGLE to Watchlist:       View:      Get Complete AGLE Trend Analysis ➞

Stock Chart of VBI Vaccines Inc.VBIV VBI Vaccines Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 139.785 Millions
Recent Price: 56.81    
Market Intelligence Score: 70
Day Percent Change: 0.282436%    
Day Change: -9999
Week Change: 86898.5%    
Year-to-date Change: 0.0%
VBIV Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add VBIV to Watchlist:       View:      Get Complete VBIV Trend Analysis ➞

Stock Chart of MEI Pharma IncMEIP MEI Pharma Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 138.9 Millions
Recent Price: 3.07    
Market Intelligence Score: 30
Day Percent Change: 10.4317%    
Day Change: 0.03
Week Change: -36.701%    
Year-to-date Change: 20.4%
MEIP Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add MEIP to Watchlist:       View:      Get Complete MEIP Trend Analysis ➞

Stock Chart of La Jolla Pharmaceutical CompanyLJPC La Jolla Pharmaceutical Company
Sector: Health Care
SubSector: Biotechnology
MarketCap: 138.185 Millions
Recent Price: 6.22    
Market Intelligence Score: 30
Day Percent Change: 0%    
Day Change: -9999
Week Change: 0%    
Year-to-date Change: 0.0%
LJPC Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add LJPC to Watchlist:       View:      Get Complete LJPC Trend Analysis ➞

Stock Chart of Agenus IncAGEN Agenus Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 137.97 Millions
Recent Price: 4.55    
Market Intelligence Score: 40
Day Percent Change: 1.78971%    
Day Change: 0.06
Week Change: -10.2564%    
Year-to-date Change: 47.2%
AGEN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add AGEN to Watchlist:       View:      Get Complete AGEN Trend Analysis ➞

Stock Chart of Molecular Partners AG ADRMOLN Molecular Partners AG ADR
Sector: Health Care
SubSector: Biotechnology
MarketCap: 133.86 Millions
Recent Price: 3.63    
Market Intelligence Score: 20
Day Percent Change: -6.6838%    
Day Change: 0.01
Week Change: 4.61095%    
Year-to-date Change: -25.5%
MOLN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add MOLN to Watchlist:       View:      Get Complete MOLN Trend Analysis ➞

Stock Chart of Compugen LtdCGEN Compugen Ltd
Sector: Health Care
SubSector: Biotechnology
MarketCap: 133.76 Millions
Recent Price: 1.36    
Market Intelligence Score: 10
Day Percent Change: -1.44928%    
Day Change: -0.01
Week Change: -4.8951%    
Year-to-date Change: -17.6%
CGEN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CGEN to Watchlist:       View:      Get Complete CGEN Trend Analysis ➞

Stock Chart of OncoCyte CorporationOCX OncoCyte Corporation
Sector: Health Care
SubSector: Biotechnology
MarketCap: 131.485 Millions
Recent Price: 3.16    
Market Intelligence Score: 50
Day Percent Change: -1.25%    
Day Change: -9999
Week Change: 14.7005%    
Year-to-date Change: 35.6%
OCX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add OCX to Watchlist:       View:      Get Complete OCX Trend Analysis ➞

Stock Chart of Vaxart, Inc.VXRT Vaxart, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 129.785 Millions
Recent Price: 0.39    
Market Intelligence Score: 30
Day Percent Change: -0.512821%    
Day Change: -0.01
Week Change: 4.77991%    
Year-to-date Change: -46.0%
VXRT Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add VXRT to Watchlist:       View:      Get Complete VXRT Trend Analysis ➞

Stock Chart of Genelux CorpGNLX Genelux Corp
Sector: Health Care
SubSector: Biotechnology
MarketCap: 127.3 Millions
Recent Price: 3.91    
Market Intelligence Score: 53
Day Percent Change: 2.38%    
Day Change: 0.08
Week Change: 0.88%    
Year-to-date Change: 45.8%
GNLX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add GNLX to Watchlist:       View:      Get Complete GNLX Trend Analysis ➞

Stock Chart of ContraFect CorporationCFRX ContraFect Corporation
Sector: Health Care
SubSector: Biotechnology
MarketCap: 126.685 Millions
Recent Price: 10.75    
Market Intelligence Score: 90
Day Percent Change: 1.41509%    
Day Change: -9999
Week Change: 47677.8%    
Year-to-date Change: 0.0%
CFRX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CFRX to Watchlist:       View:      Get Complete CFRX Trend Analysis ➞

Stock Chart of Macrogenics IncMGNX Macrogenics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 126.41 Millions
Recent Price: 1.53    
Market Intelligence Score: 30
Day Percent Change: 4.08163%    
Day Change: -0.05
Week Change: -11.5607%    
Year-to-date Change: -53.6%
MGNX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add MGNX to Watchlist:       View:      Get Complete MGNX Trend Analysis ➞

Stock Chart of Zentalis Pharmaceuticals IncZNTL Zentalis Pharmaceuticals Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 126.24 Millions
Recent Price: 1.42    
Market Intelligence Score: 40
Day Percent Change: 0%    
Day Change: 0.23
Week Change: -11.25%    
Year-to-date Change: -52.7%
ZNTL Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ZNTL to Watchlist:       View:      Get Complete ZNTL Trend Analysis ➞

Stock Chart of Sierra Oncology, Inc.SRRA Sierra Oncology, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 125.185 Millions
Recent Price: 14.95    
Market Intelligence Score: 30
Day Percent Change: 3.67545%    
Day Change: -9999
Week Change: -72.8132%    
Year-to-date Change: 0.0%
SRRA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add SRRA to Watchlist:       View:      Get Complete SRRA Trend Analysis ➞

Stock Chart of Ophthotech CorporationOPHT Ophthotech Corporation
Sector: Health Care
SubSector: Biotechnology
MarketCap: 124.59 Millions
Recent Price: 4.76    
Market Intelligence Score: 10
Day Percent Change: -1.0395%    
Day Change: -9999
Week Change: -76.5863%    
Year-to-date Change: 0.0%
OPHT Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add OPHT to Watchlist:       View:      Get Complete OPHT Trend Analysis ➞

Stock Chart of Selecta Biosciences, Inc.SELB Selecta Biosciences, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 123.885 Millions
Recent Price: 2.70    
Market Intelligence Score: 60
Day Percent Change: 0%    
Day Change: -9999
Week Change: 170%    
Year-to-date Change: 0.0%
SELB Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add SELB to Watchlist:       View:      Get Complete SELB Trend Analysis ➞

Stock Chart of Tyme Technologies, Inc.TYME Tyme Technologies, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 123.885 Millions
Recent Price: 0.31    
Market Intelligence Score: 20
Day Percent Change: 0%    
Day Change: -9999
Week Change: 0%    
Year-to-date Change: 0.0%
TYME Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add TYME to Watchlist:       View:      Get Complete TYME Trend Analysis ➞

Stock Chart of ObsEva SAOBSV ObsEva SA
Sector: Health Care
SubSector: Biotechnology
MarketCap: 123.585 Millions
Recent Price: 0.08    
Market Intelligence Score: 20
Day Percent Change: 1.20482%    
Day Change: -9999
Week Change: -8.79479%    
Year-to-date Change: 0.0%
OBSV Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add OBSV to Watchlist:       View:      Get Complete OBSV Trend Analysis ➞

Stock Chart of Protalix BioTherapeutics IncPLX Protalix BioTherapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 122.79 Millions
Recent Price: 1.87    
Market Intelligence Score: 100
Day Percent Change: -2.09424%    
Day Change: 0.01
Week Change: 19.1159%    
Year-to-date Change: -5.1%
PLX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PLX to Watchlist:       View:      Get Complete PLX Trend Analysis ➞

Stock Chart of Protara Therapeutics IncTARA Protara Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 121.53 Millions
Recent Price: 3.03    
Market Intelligence Score: 0
Day Percent Change: -1.30293%    
Day Change: 0.07
Week Change: -2.57235%    
Year-to-date Change: -45.7%
TARA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add TARA to Watchlist:       View:      Get Complete TARA Trend Analysis ➞

Stock Chart of Spero Therapeutics IncSPRO Spero Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 120.99 Millions
Recent Price: 1.90    
Market Intelligence Score: 0
Day Percent Change: 0%    
Day Change: 0.03
Week Change: -4.0404%    
Year-to-date Change: 75.9%
SPRO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add SPRO to Watchlist:       View:      Get Complete SPRO Trend Analysis ➞

Stock Chart of Corbus Pharmaceuticals Holdings IncCRBP Corbus Pharmaceuticals Holdings Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 120.84 Millions
Recent Price: 11.62    
Market Intelligence Score: 100
Day Percent Change: 13.1451%    
Day Change: 0.48
Week Change: 21.9307%    
Year-to-date Change: -3.5%
CRBP Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CRBP to Watchlist:       View:      Get Complete CRBP Trend Analysis ➞

Stock Chart of Enochian Biosciences Inc.ENOB Enochian Biosciences Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 120.685 Millions
Recent Price: 0.70    
Market Intelligence Score: 30
Day Percent Change: 0%    
Day Change: -9999
Week Change: 0%    
Year-to-date Change: 0.0%
ENOB Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ENOB to Watchlist:       View:      Get Complete ENOB Trend Analysis ➞

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Performance: Year-to-date, Week and Day
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