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Best Biotech Stocks

Quick Read: Best Biotech Stocks List By Performances & Trends:
Daily, Weekly, Year-to-Date, Market Cap (Size) & Technical Trends
Best Biotech Stocks Views: Quick Browse View, Summary & Slide Show View

12Stocks.com Biotech Stocks Performances & Trends Daily
October 3, 2025 - All trends (long term, mid-term and short term) for Biotech sector looks good.

The overall market intelligence score is 100 (0-bearish to 100-bullish) which puts Biotech sector in short term bullish trend.

The market intelligence score from previous trading session is 90 and an improvement of trend continues.

 Year To Date Performance: 12.1001 %
 Weekly Performance: 5.2853 %
 Daily Performance: 1.18355 %
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Biotech Sector Trend
100 / 100
Here are the market intelligence trend scores of the most requested Biotech stocks at 12Stocks.com (click stock name for detailed review):

12Stocks.com: Investing in Biotech sector with Stocks
The following table helps investors and traders sort through current performance and trends (as measured by market intelligence score) of various stocks in the Biotech sector.

Quick View: Move mouse or cursor over stock symbol (ticker) to view short-term Technical chart and over stock name to view long term chart. Click on to add stock symbol to your watchlist and to view watchlist. Click on any ticker or stock name for detailed market intelligence report for that stock.

12Stocks.com Performance of Stocks in Biotech Sector

TickerStock NameWatchlistCategoryRecent PriceMarket Intelligence ScoreChange %YTD Change%
DMACDiaMedica  Biotechnology7.00602.04%27.04%
IOVAIovance Bio Biotechnology2.25601.81%-71.12%
NUVLNuvalent  Biotechnology83.86601.55%4.84%
AVXLAnavex Life Biotechnology9.13601.33%-24.86%
RPRXRoyalty Pharma Biotechnology36.50600.50%43.42%
BPMCBlueprint Medicines Biotechnology129.46600.14%48.46%
APLSApellis  Biotechnology23.13600.13%-30.25%
ALNYAlnylam  Biotechnology460.99600.07%97.32%
BCLIBrainstorm Cell Biotechnology0.65600.03%-69.85%
RETAReata  Biotechnology172.36600.00%0.00%
SELBSelecta  Biotechnology2.70600.00%0.00%
DCPHDeciphera  Biotechnology25.59600.00%0.00%
KRTXKaruna  Biotechnology329.83600.00%0.00%
HARPHarpoon  Biotechnology23.01600.00%0.00%
ARLZAralez  Biotechnology30.6260-0.26%0.00%
CRNXCrinetics  Biotechnology41.5060-0.26%-19.50%
AGLEAeglea Bio Biotechnology27.6060-0.29%0.00%
QUREuniQure N.V Biotechnology54.5060-0.89%201.94%
SNDXSyndax  Biotechnology15.4560-1.47%9.73%
ADPTAdaptive nologies Biotechnology14.2360-2.27%129.89%
ENTAEnanta  Biotechnology10.3360-2.64%84.79%
CRVSCorvus  Biotechnology7.0460-3.10%29.56%
ORICORIC  Biotechnology11.3360-3.25%37.17%
AUTLAutolus  Biotechnology1.6160-3.59%-38.78%
TARAProtara  Biotechnology4.2260-4.31%-24.37%
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Performance: Year-to-date, Week and Day
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Detailed Overview of Biotech Stocks
Biotech Technical Overview, Leaders & Laggards, Top Biotech ETF Funds & Detailed Biotech Stocks List, Charts, Trends & More

Biotech Sector: Technical Analysis, Trends & YTD Performance
Biotech sector, as represented by XBI, an exchange-traded fund [ETF] that holds basket of Biotech stocks (e.g, Amgen, Celgene) is up by 12.1001% and is currently underperforming the overall market by -2.6578% year-to-date. Below is a quick view of Technical charts and trends:

XBI Weekly Chart
Long Term Trend: Very Good
Medium Term Trend: Very Good

XBI Daily Chart
Short Term Trend: Very Good
Overall Trend Score: 100
YTD Performance: 12.1001%
**Trend Scores & Views Are Only For Educational Purposes And Not For Investing


12Stocks.com: Top Performing Biotech Sector Stocks
Hot Biotech Stocks of 2025 We try to spot trends by analyzing the performances of various stocks or components within Biotech sector and try to find best performing stocks. The movers and shakers. The winners and losers.

The top performing Biotech sector stocks year to date are
Vor Biopharma[3175%] Nanobiotix ADR[581%] I-Mab ADR[358%]
Monopar [337%] Nektar [320%] DBV Technologies[277%]
Celcuity [276%] Galectin [263%] Cidara [261%]
Lineage Cell[234%] ATAI Life[221%]
View complete list of Biotech stocks by year-to-date performance

Now, more recently, over last week, the top performing Biotech sector stocks on the move are
Athersys [193287%] VBI Vaccines[86898.5%] ContraFect [47677.8%]
Clovis Oncology[39610.5%] NanoString Technologies[17224.7%] Neptune Wellness[14100%]
Achillion [10033.3%] Nymox [8258.5%] Epizyme [5739.5%]
Portola [4717.6%] Strongbridge Biopharma[3417.5%]
View complete list of Biotech stocks by weekly performance

Unfortunately not all Biotech stocks have done well this year. Investors of these stocks hope they have seen the worst and hope that these stocks are set to bounce back. The bearish stocks in this index year to date (YTD) are
Vaxxinity [-100%] Petros [-100%] Translate Bio[-95%]
Palatin Technologies[-93%] Syros [-91%] Pliant [-89%]
Affimed N.V[-87%] MoonLake Immuno[-86%] Unity nology[-86%]
Sarepta [-82%] Kala Bio[-80%] IGM [-80%]
.
Investors can get enhanced performance by riding the current stock trends. Using complex algorithms, 12Stocks.com has come up with market intelligence scores (on 0-bearish to 100-bullish scale) to identify best trending stocks. Top trending Biotech stocks are
Taysha Gene[100] DBV Technologies[100] Valneva SE[100]
Prime Medicine[100] AlloVir [100] Sarepta [100]
Monopar [100] Cara [100] Absci Corp[100]
Spruce [100] Cabaletta Bio[100] Compugen [100]
View complete list of Biotech stocks by 12Stocks.com trends

12Stocks.com: Investing in Biotech Sector using Exchange Traded Funds
The following table shows list of key exchange traded funds (ETF) that help investors track Biotech Index. For detailed view, check out our ETF Funds section of our website.

Quick View: Move mouse or cursor over ETF symbol (ticker) to view short-term Technical chart and over ETF name to view long term chart. Click on ticker or stock name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist.

12Stocks.com List of ETFs that track Biotech Index

TickerETF NameWatchlistRecent PriceMarket Intelligence ScoreChange %Week %Year-to-date %
UBIOBiotechnology  73.3480-0.0681292260.7480%
HCRFEdge Multifactor 67.142309999NA
SICKHealthcare Bear 3X 37.903609999NA
LABSBiotech Bear 1X 24.185609999NA
BTECPrincipal Healthcare Innovators 39.493001.023280%
 Market Intelligence Score (0-Bearish to 100-Bullish)
12Stocks.com: Charts, Trends, Fundamental Data and Performances of Biotech Stocks
We now take in-depth look at all Biotech stocks including charts, multi-period performances and overall trends (as measured by market intelligence score).

One can sort Biotech stocks (click link to choose) by Daily, Weekly and by Year-to-Date performances. Also, one can sort by size of the company or by market capitalization.
Select Your Default Chart Type:
Long Term Chart Daily Chart Weekly Chart 
Long Term Chart (Default)
Weekly Chart Example
Daily Chart Example
Click on stock symbol or name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist. Quick View: Move mouse or cursor over "Daily" to quickly view daily Technical stock chart and over "Weekly" to view weekly Technical stock chart.

Stock Chart of DiaMedica Therapeutics IncDMAC DiaMedica Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 317.37 Millions
Recent Price: 7.00    
Market Intelligence Score: 60
Day Percent Change: 2.04082%    
Day Change: -0.07
Week Change: 2.18978%    
Year-to-date Change: 27.0%
DMAC Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add DMAC to Watchlist:       View:      Get Complete DMAC Trend Analysis ➞

Stock Chart of Iovance Biotherapeutics IncIOVA Iovance Biotherapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 901.02 Millions
Recent Price: 2.25    
Market Intelligence Score: 60
Day Percent Change: 1.80995%    
Day Change: 0.01
Week Change: 6.13208%    
Year-to-date Change: -71.1%
IOVA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add IOVA to Watchlist:       View:      Get Complete IOVA Trend Analysis ➞

Stock Chart of Nuvalent IncNUVL Nuvalent Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 5832.56 Millions
Recent Price: 83.86    
Market Intelligence Score: 60
Day Percent Change: 1.55001%    
Day Change: 0.41
Week Change: 5.43123%    
Year-to-date Change: 4.8%
NUVL Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add NUVL to Watchlist:       View:      Get Complete NUVL Trend Analysis ➞

Stock Chart of Anavex Life Sciences CorporationAVXL Anavex Life Sciences Corporation
Sector: Health Care
SubSector: Biotechnology
MarketCap: 807.4 Millions
Recent Price: 9.13    
Market Intelligence Score: 60
Day Percent Change: 1.33185%    
Day Change: -0.13
Week Change: 8.17536%    
Year-to-date Change: -24.9%
AVXL Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add AVXL to Watchlist:       View:      Get Complete AVXL Trend Analysis ➞

Stock Chart of Royalty Pharma plcRPRX Royalty Pharma plc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 21036.9 Millions
Recent Price: 36.50    
Market Intelligence Score: 60
Day Percent Change: 0.495595%    
Day Change: 0.21
Week Change: 2.04082%    
Year-to-date Change: 43.4%
RPRX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add RPRX to Watchlist:       View:      Get Complete RPRX Trend Analysis ➞

Stock Chart of Blueprint Medicines CorporationBPMC Blueprint Medicines Corporation
Sector: Health Care
SubSector: Biotechnology
MarketCap: 3113.55 Millions
Recent Price: 129.46    
Market Intelligence Score: 60
Day Percent Change: 0.139233%    
Day Change: -9999
Week Change: 0.707896%    
Year-to-date Change: 48.5%
BPMC Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add BPMC to Watchlist:       View:      Get Complete BPMC Trend Analysis ➞

Stock Chart of Apellis Pharmaceuticals IncAPLS Apellis Pharmaceuticals Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 3552.54 Millions
Recent Price: 23.13    
Market Intelligence Score: 60
Day Percent Change: 0.12987%    
Day Change: -0.16
Week Change: 1.62566%    
Year-to-date Change: -30.2%
APLS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add APLS to Watchlist:       View:      Get Complete APLS Trend Analysis ➞

Stock Chart of Alnylam Pharmaceuticals IncALNY Alnylam Pharmaceuticals Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 59247.7 Millions
Recent Price: 460.99    
Market Intelligence Score: 60
Day Percent Change: 0.0738088%    
Day Change: -3.48
Week Change: 0.571591%    
Year-to-date Change: 97.3%
ALNY Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ALNY to Watchlist:       View:      Get Complete ALNY Trend Analysis ➞

Stock Chart of Brainstorm Cell Therapeutics Inc.BCLI Brainstorm Cell Therapeutics Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 141.285 Millions
Recent Price: 0.65    
Market Intelligence Score: 60
Day Percent Change: 0.0310078%    
Day Change: -9999
Week Change: 1.6063%    
Year-to-date Change: -69.9%
BCLI Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add BCLI to Watchlist:       View:      Get Complete BCLI Trend Analysis ➞

Stock Chart of Reata Pharmaceuticals, Inc.RETA Reata Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 4425.05 Millions
Recent Price: 172.36    
Market Intelligence Score: 60
Day Percent Change: 0%    
Day Change: -9999
Week Change: 0.18018%    
Year-to-date Change: 0.0%
RETA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add RETA to Watchlist:       View:      Get Complete RETA Trend Analysis ➞

Stock Chart of Selecta Biosciences, Inc.SELB Selecta Biosciences, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 123.885 Millions
Recent Price: 2.70    
Market Intelligence Score: 60
Day Percent Change: 0%    
Day Change: -9999
Week Change: 170%    
Year-to-date Change: 0.0%
SELB Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add SELB to Watchlist:       View:      Get Complete SELB Trend Analysis ➞

Stock Chart of Deciphera Pharmaceuticals, Inc.DCPH Deciphera Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 2329.95 Millions
Recent Price: 25.59    
Market Intelligence Score: 60
Day Percent Change: 0%    
Day Change: -9999
Week Change: 0.117371%    
Year-to-date Change: 0.0%
DCPH Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add DCPH to Watchlist:       View:      Get Complete DCPH Trend Analysis ➞

Stock Chart of Karuna Therapeutics, Inc.KRTX Karuna Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 2190.75 Millions
Recent Price: 329.83    
Market Intelligence Score: 60
Day Percent Change: 0%    
Day Change: -9999
Week Change: 3.08798%    
Year-to-date Change: 0.0%
KRTX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add KRTX to Watchlist:       View:      Get Complete KRTX Trend Analysis ➞

Stock Chart of Harpoon Therapeutics, Inc.HARP Harpoon Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 334.885 Millions
Recent Price: 23.01    
Market Intelligence Score: 60
Day Percent Change: 0%    
Day Change: -9999
Week Change: 0.305144%    
Year-to-date Change: 0.0%
HARP Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add HARP to Watchlist:       View:      Get Complete HARP Trend Analysis ➞

Stock Chart of Aralez Pharmaceuticals Inc.ARLZ Aralez Pharmaceuticals Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 155.5 Millions
Recent Price: 30.62    
Market Intelligence Score: 60
Day Percent Change: -0.260586%    
Day Change: -9999
Week Change: 3.16712%    
Year-to-date Change: 0.0%
ARLZ Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ARLZ to Watchlist:       View:      Get Complete ARLZ Trend Analysis ➞

Stock Chart of Crinetics Pharmaceuticals IncCRNX Crinetics Pharmaceuticals Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 3353.61 Millions
Recent Price: 41.50    
Market Intelligence Score: 60
Day Percent Change: -0.26436%    
Day Change: 0.31
Week Change: 17.9648%    
Year-to-date Change: -19.5%
CRNX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CRNX to Watchlist:       View:      Get Complete CRNX Trend Analysis ➞

Stock Chart of Aeglea BioTherapeutics, Inc.AGLE Aeglea BioTherapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 140.085 Millions
Recent Price: 27.60    
Market Intelligence Score: 60
Day Percent Change: -0.289017%    
Day Change: -9999
Week Change: 1.7324%    
Year-to-date Change: 0.0%
AGLE Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add AGLE to Watchlist:       View:      Get Complete AGLE Trend Analysis ➞

Stock Chart of uniQure N.VQURE uniQure N.V
Sector: Health Care
SubSector: Biotechnology
MarketCap: 984.86 Millions
Recent Price: 54.50    
Market Intelligence Score: 60
Day Percent Change: -0.891071%    
Day Change: 0.07
Week Change: 16.453%    
Year-to-date Change: 201.9%
QURE Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add QURE to Watchlist:       View:      Get Complete QURE Trend Analysis ➞

Stock Chart of Syndax Pharmaceuticals IncSNDX Syndax Pharmaceuticals Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1467.86 Millions
Recent Price: 15.45    
Market Intelligence Score: 60
Day Percent Change: -1.46684%    
Day Change: 0.1
Week Change: 2.93138%    
Year-to-date Change: 9.7%
SNDX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add SNDX to Watchlist:       View:      Get Complete SNDX Trend Analysis ➞

Stock Chart of Adaptive Biotechnologies CorpADPT Adaptive Biotechnologies Corp
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1956.72 Millions
Recent Price: 14.23    
Market Intelligence Score: 60
Day Percent Change: -2.26648%    
Day Change: 0.34
Week Change: 10.9984%    
Year-to-date Change: 129.9%
ADPT Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ADPT to Watchlist:       View:      Get Complete ADPT Trend Analysis ➞

Stock Chart of Enanta Pharmaceuticals IncENTA Enanta Pharmaceuticals Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 189.19 Millions
Recent Price: 10.33    
Market Intelligence Score: 60
Day Percent Change: -2.63902%    
Day Change: -0.23
Week Change: 32.2663%    
Year-to-date Change: 84.8%
ENTA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ENTA to Watchlist:       View:      Get Complete ENTA Trend Analysis ➞

Stock Chart of Corvus Pharmaceuticals IncCRVS Corvus Pharmaceuticals Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 459.01 Millions
Recent Price: 7.04    
Market Intelligence Score: 60
Day Percent Change: -3.09917%    
Day Change: 0.1
Week Change: 8.56481%    
Year-to-date Change: 29.6%
CRVS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CRVS to Watchlist:       View:      Get Complete CRVS Trend Analysis ➞

Stock Chart of ORIC Pharmaceuticals IncORIC ORIC Pharmaceuticals Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1056.7 Millions
Recent Price: 11.33    
Market Intelligence Score: 60
Day Percent Change: -3.24509%    
Day Change: 0.18
Week Change: 8.3174%    
Year-to-date Change: 37.2%
ORIC Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ORIC to Watchlist:       View:      Get Complete ORIC Trend Analysis ➞

Stock Chart of Autolus Therapeutics plc ADRAUTL Autolus Therapeutics plc ADR
Sector: Health Care
SubSector: Biotechnology
MarketCap: 388.56 Millions
Recent Price: 1.61    
Market Intelligence Score: 60
Day Percent Change: -3.59281%    
Day Change: 0.02
Week Change: 3.20513%    
Year-to-date Change: -38.8%
AUTL Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add AUTL to Watchlist:       View:      Get Complete AUTL Trend Analysis ➞

Stock Chart of Protara Therapeutics IncTARA Protara Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 121.53 Millions
Recent Price: 4.22    
Market Intelligence Score: 60
Day Percent Change: -4.30839%    
Day Change: 0.07
Week Change: 3.43137%    
Year-to-date Change: -24.4%
TARA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add TARA to Watchlist:       View:      Get Complete TARA Trend Analysis ➞

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