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Best Biotech Stocks

Quick Read: Best Biotech Stocks List By Performances & Trends:
Daily, Weekly, Year-to-Date, Market Cap (Size) & Technical Trends
Best Biotech Stocks Views: Quick Browse View, Summary & Slide Show View

12Stocks.com Biotech Stocks Performances & Trends Daily
October 3, 2025 - All trends (long term, mid-term and short term) for Biotech sector looks good.

The overall market intelligence score is 100 (0-bearish to 100-bullish) which puts Biotech sector in short term bullish trend.

The market intelligence score from previous trading session is 90 and an improvement of trend continues.

 Year To Date Performance: 12.1001 %
 Weekly Performance: 5.2853 %
 Daily Performance: 1.18355 %
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Biotech Sector Trend
100 / 100
Here are the market intelligence trend scores of the most requested Biotech stocks at 12Stocks.com (click stock name for detailed review):

12Stocks.com: Investing in Biotech sector with Stocks
The following table helps investors and traders sort through current performance and trends (as measured by market intelligence score) of various stocks in the Biotech sector.

Quick View: Move mouse or cursor over stock symbol (ticker) to view short-term Technical chart and over stock name to view long term chart. Click on to add stock symbol to your watchlist and to view watchlist. Click on any ticker or stock name for detailed market intelligence report for that stock.

12Stocks.com Performance of Stocks in Biotech Sector

TickerStock NameWatchlistCategoryRecent PriceMarket Intelligence ScoreChange %YTD Change%
ETNB89bio  Biotechnology14.84901.02%85.96%
PRTAProthena  Biotechnology9.99900.71%-26.92%
YMABY-Mabs  Biotechnology8.61900.23%8.03%
MDGLMadrigal  Biotechnology449.54900.09%43.27%
XNCRXencor  Biotechnology11.83900.00%-50.27%
THTXTheratechnologies  Biotechnology3.39900.00%84.24%
CRBPCorbus  Biotechnology13.0090-0.31%7.97%
AGIOAgios  Biotechnology39.9490-0.32%25.44%
BBIOBridgeBio Pharma Biotechnology53.2890-0.37%88.94%
INCYyte Corp Biotechnology86.3090-0.46%24.12%
KURAKura Oncology Biotechnology9.1590-0.54%5.41%
FDMT4D Molecular Biotechnology8.6890-0.63%48.80%
PHARPharming  Biotechnology15.2390-1.04%45.60%
ARWRArrowhead  Biotechnology34.5990-1.20%76.03%
ASNDAscendis Pharma Biotechnology200.8290-1.61%45.52%
CTMXCytomX  Biotechnology3.2990-1.79%210.38%
RLAYRelay  Biotechnology5.2290-1.88%21.40%
GERNGeron Corp Biotechnology1.3890-2.48%-61.81%
DRTSAlpha Tau Biotechnology4.3790-3.10%40.97%
ERASErasca  Biotechnology2.1390-3.39%-20.93%
FATEFate  Biotechnology1.2090-4.40%-33.24%
LYELLyell Immunopharma Biotechnology15.8190-4.47%22.56%
MRVIMaravai Life Biotechnology2.9690-5.57%-45.99%
KLDOKaleido  Biotechnology0.01809,900.00%NA
IMABI-Mab ADR Biotechnology4.14807.38%357.51%
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Performance: Year-to-date, Week and Day
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Detailed Overview of Biotech Stocks
Biotech Technical Overview, Leaders & Laggards, Top Biotech ETF Funds & Detailed Biotech Stocks List, Charts, Trends & More

Biotech Sector: Technical Analysis, Trends & YTD Performance
Biotech sector, as represented by XBI, an exchange-traded fund [ETF] that holds basket of Biotech stocks (e.g, Amgen, Celgene) is up by 12.1001% and is currently underperforming the overall market by -2.6578% year-to-date. Below is a quick view of Technical charts and trends:

XBI Weekly Chart
Long Term Trend: Very Good
Medium Term Trend: Very Good

XBI Daily Chart
Short Term Trend: Very Good
Overall Trend Score: 100
YTD Performance: 12.1001%
**Trend Scores & Views Are Only For Educational Purposes And Not For Investing


12Stocks.com: Top Performing Biotech Sector Stocks
Hot Biotech Stocks of 2025 We try to spot trends by analyzing the performances of various stocks or components within Biotech sector and try to find best performing stocks. The movers and shakers. The winners and losers.

The top performing Biotech sector stocks year to date are
Vor Biopharma[3175%] Nanobiotix ADR[581%] I-Mab ADR[358%]
Monopar [337%] Nektar [320%] DBV Technologies[277%]
Celcuity [276%] Galectin [263%] Cidara [261%]
Lineage Cell[234%] ATAI Life[221%]
View complete list of Biotech stocks by year-to-date performance

Now, more recently, over last week, the top performing Biotech sector stocks on the move are
Athersys [193287%] VBI Vaccines[86898.5%] ContraFect [47677.8%]
Clovis Oncology[39610.5%] NanoString Technologies[17224.7%] Neptune Wellness[14100%]
Achillion [10033.3%] Nymox [8258.5%] Epizyme [5739.5%]
Portola [4717.6%] Strongbridge Biopharma[3417.5%]
View complete list of Biotech stocks by weekly performance

Unfortunately not all Biotech stocks have done well this year. Investors of these stocks hope they have seen the worst and hope that these stocks are set to bounce back. The bearish stocks in this index year to date (YTD) are
Vaxxinity [-100%] Petros [-100%] Translate Bio[-95%]
Palatin Technologies[-93%] Syros [-91%] Pliant [-89%]
Affimed N.V[-87%] MoonLake Immuno[-86%] Unity nology[-86%]
Sarepta [-82%] Kala Bio[-80%] IGM [-80%]
.
Investors can get enhanced performance by riding the current stock trends. Using complex algorithms, 12Stocks.com has come up with market intelligence scores (on 0-bearish to 100-bullish scale) to identify best trending stocks. Top trending Biotech stocks are
Taysha Gene[100] DBV Technologies[100] Valneva SE[100]
Prime Medicine[100] AlloVir [100] Sarepta [100]
Monopar [100] Cara [100] Absci Corp[100]
Spruce [100] Cabaletta Bio[100] Compugen [100]
View complete list of Biotech stocks by 12Stocks.com trends

12Stocks.com: Investing in Biotech Sector using Exchange Traded Funds
The following table shows list of key exchange traded funds (ETF) that help investors track Biotech Index. For detailed view, check out our ETF Funds section of our website.

Quick View: Move mouse or cursor over ETF symbol (ticker) to view short-term Technical chart and over ETF name to view long term chart. Click on ticker or stock name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist.

12Stocks.com List of ETFs that track Biotech Index

TickerETF NameWatchlistRecent PriceMarket Intelligence ScoreChange %Week %Year-to-date %
UBIOBiotechnology  73.3480-0.0681292260.7480%
HCRFEdge Multifactor 67.142309999NA
SICKHealthcare Bear 3X 37.903609999NA
LABSBiotech Bear 1X 24.185609999NA
BTECPrincipal Healthcare Innovators 39.493001.023280%
 Market Intelligence Score (0-Bearish to 100-Bullish)
12Stocks.com: Charts, Trends, Fundamental Data and Performances of Biotech Stocks
We now take in-depth look at all Biotech stocks including charts, multi-period performances and overall trends (as measured by market intelligence score).

One can sort Biotech stocks (click link to choose) by Daily, Weekly and by Year-to-Date performances. Also, one can sort by size of the company or by market capitalization.
Select Your Default Chart Type:
Long Term Chart Daily Chart Weekly Chart 
Long Term Chart (Default)
Weekly Chart Example
Daily Chart Example
Click on stock symbol or name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist. Quick View: Move mouse or cursor over "Daily" to quickly view daily Technical stock chart and over "Weekly" to view weekly Technical stock chart.

Stock Chart of 89bio IncETNB 89bio Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1315.49 Millions
Recent Price: 14.84    
Market Intelligence Score: 90
Day Percent Change: 1.0211%    
Day Change: 0.09
Week Change: 0.952381%    
Year-to-date Change: 86.0%
ETNB Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ETNB to Watchlist:       View:      Get Complete ETNB Trend Analysis ➞

Stock Chart of Prothena Corporation plcPRTA Prothena Corporation plc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 460.25 Millions
Recent Price: 9.99    
Market Intelligence Score: 90
Day Percent Change: 0.705645%    
Day Change: 0.04
Week Change: 7.18884%    
Year-to-date Change: -26.9%
PRTA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PRTA to Watchlist:       View:      Get Complete PRTA Trend Analysis ➞

Stock Chart of Y-Mabs Therapeutics IncYMAB Y-Mabs Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 389.86 Millions
Recent Price: 8.61    
Market Intelligence Score: 90
Day Percent Change: 0.232829%    
Day Change: 0.01
Week Change: 0.34965%    
Year-to-date Change: 8.0%
YMAB Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add YMAB to Watchlist:       View:      Get Complete YMAB Trend Analysis ➞

Stock Chart of Madrigal Pharmaceuticals IncMDGL Madrigal Pharmaceuticals Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 9648.69 Millions
Recent Price: 449.54    
Market Intelligence Score: 90
Day Percent Change: 0.0890591%    
Day Change: 15.43
Week Change: 5.31815%    
Year-to-date Change: 43.3%
MDGL Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add MDGL to Watchlist:       View:      Get Complete MDGL Trend Analysis ➞

Stock Chart of Xencor IncXNCR Xencor Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 609.81 Millions
Recent Price: 11.83    
Market Intelligence Score: 90
Day Percent Change: 0%    
Day Change: -0.07
Week Change: 12.7741%    
Year-to-date Change: -50.3%
XNCR Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add XNCR to Watchlist:       View:      Get Complete XNCR Trend Analysis ➞

Stock Chart of Theratechnologies IncTHTX Theratechnologies Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 150.35 Millions
Recent Price: 3.39    
Market Intelligence Score: 90
Day Percent Change: 0%    
Day Change: 0
Week Change: 2.41692%    
Year-to-date Change: 84.2%
THTX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add THTX to Watchlist:       View:      Get Complete THTX Trend Analysis ➞

Stock Chart of Corbus Pharmaceuticals Holdings IncCRBP Corbus Pharmaceuticals Holdings Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 120.84 Millions
Recent Price: 13.00    
Market Intelligence Score: 90
Day Percent Change: -0.306748%    
Day Change: 0.48
Week Change: 12.8472%    
Year-to-date Change: 8.0%
CRBP Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CRBP to Watchlist:       View:      Get Complete CRBP Trend Analysis ➞

Stock Chart of Agios Pharmaceuticals IncAGIO Agios Pharmaceuticals Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 2092.24 Millions
Recent Price: 39.94    
Market Intelligence Score: 90
Day Percent Change: -0.324432%    
Day Change: 1.38
Week Change: 7.02036%    
Year-to-date Change: 25.4%
AGIO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add AGIO to Watchlist:       View:      Get Complete AGIO Trend Analysis ➞

Stock Chart of BridgeBio Pharma IncBBIO BridgeBio Pharma Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 10204.6 Millions
Recent Price: 53.28    
Market Intelligence Score: 90
Day Percent Change: -0.373972%    
Day Change: 1.35
Week Change: 5.1925%    
Year-to-date Change: 88.9%
BBIO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add BBIO to Watchlist:       View:      Get Complete BBIO Trend Analysis ➞

Stock Chart of Incyte CorpINCY Incyte Corp
Sector: Health Care
SubSector: Biotechnology
MarketCap: 16918.7 Millions
Recent Price: 86.30    
Market Intelligence Score: 90
Day Percent Change: -0.461361%    
Day Change: -0.12
Week Change: 2.54278%    
Year-to-date Change: 24.1%
INCY Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add INCY to Watchlist:       View:      Get Complete INCY Trend Analysis ➞

Stock Chart of Kura Oncology IncKURA Kura Oncology Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 713.47 Millions
Recent Price: 9.15    
Market Intelligence Score: 90
Day Percent Change: -0.543478%    
Day Change: 0.39
Week Change: 9.18854%    
Year-to-date Change: 5.4%
KURA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add KURA to Watchlist:       View:      Get Complete KURA Trend Analysis ➞

Stock Chart of 4D Molecular Therapeutics IncFDMT 4D Molecular Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 339.53 Millions
Recent Price: 8.68    
Market Intelligence Score: 90
Day Percent Change: -0.630011%    
Day Change: 0
Week Change: 2.78436%    
Year-to-date Change: 48.8%
FDMT Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add FDMT to Watchlist:       View:      Get Complete FDMT Trend Analysis ➞

Stock Chart of Pharming Group N.V. ADRPHAR Pharming Group N.V. ADR
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1045.46 Millions
Recent Price: 15.23    
Market Intelligence Score: 90
Day Percent Change: -1.03964%    
Day Change: 0.44
Week Change: 3.11442%    
Year-to-date Change: 45.6%
PHAR Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PHAR to Watchlist:       View:      Get Complete PHAR Trend Analysis ➞

Stock Chart of Arrowhead Pharmaceuticals IncARWR Arrowhead Pharmaceuticals Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 4019.84 Millions
Recent Price: 34.59    
Market Intelligence Score: 90
Day Percent Change: -1.19966%    
Day Change: 0.55
Week Change: 5.36095%    
Year-to-date Change: 76.0%
ARWR Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ARWR to Watchlist:       View:      Get Complete ARWR Trend Analysis ➞

Stock Chart of Ascendis Pharma A/S ADRASND Ascendis Pharma A/S ADR
Sector: Health Care
SubSector: Biotechnology
MarketCap: 12467.8 Millions
Recent Price: 200.82    
Market Intelligence Score: 90
Day Percent Change: -1.61188%    
Day Change: -1.96
Week Change: 3.90108%    
Year-to-date Change: 45.5%
ASND Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ASND to Watchlist:       View:      Get Complete ASND Trend Analysis ➞

Stock Chart of CytomX Therapeutics IncCTMX CytomX Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 376 Millions
Recent Price: 3.29    
Market Intelligence Score: 90
Day Percent Change: -1.79104%    
Day Change: 0.06
Week Change: 36.5145%    
Year-to-date Change: 210.4%
CTMX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CTMX to Watchlist:       View:      Get Complete CTMX Trend Analysis ➞

Stock Chart of Relay Therapeutics IncRLAY Relay Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 710.33 Millions
Recent Price: 5.22    
Market Intelligence Score: 90
Day Percent Change: -1.8797%    
Day Change: 0.01
Week Change: 15.4867%    
Year-to-date Change: 21.4%
RLAY Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add RLAY to Watchlist:       View:      Get Complete RLAY Trend Analysis ➞

Stock Chart of Geron CorpGERN Geron Corp
Sector: Health Care
SubSector: Biotechnology
MarketCap: 893.22 Millions
Recent Price: 1.38    
Market Intelligence Score: 90
Day Percent Change: -2.48227%    
Day Change: 0.04
Week Change: 3.38346%    
Year-to-date Change: -61.8%
GERN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add GERN to Watchlist:       View:      Get Complete GERN Trend Analysis ➞

Stock Chart of Alpha Tau Medical LtdDRTS Alpha Tau Medical Ltd
Sector: Health Care
SubSector: Biotechnology
MarketCap: 304.92 Millions
Recent Price: 4.37    
Market Intelligence Score: 90
Day Percent Change: -3.10421%    
Day Change: 0.08
Week Change: 5.17449%    
Year-to-date Change: 41.0%
DRTS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add DRTS to Watchlist:       View:      Get Complete DRTS Trend Analysis ➞

Stock Chart of Erasca IncERAS Erasca Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 456.71 Millions
Recent Price: 2.13    
Market Intelligence Score: 90
Day Percent Change: -3.39367%    
Day Change: 0.04
Week Change: 11.7801%    
Year-to-date Change: -20.9%
ERAS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ERAS to Watchlist:       View:      Get Complete ERAS Trend Analysis ➞

Stock Chart of Fate Therapeutics IncFATE Fate Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 116.48 Millions
Recent Price: 1.20    
Market Intelligence Score: 90
Day Percent Change: -4.4%    
Day Change: -0.02
Week Change: 18.3168%    
Year-to-date Change: -33.2%
FATE Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add FATE to Watchlist:       View:      Get Complete FATE Trend Analysis ➞

Stock Chart of Lyell Immunopharma IncLYEL Lyell Immunopharma Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 233.42 Millions
Recent Price: 15.81    
Market Intelligence Score: 90
Day Percent Change: -4.4713%    
Day Change: 0
Week Change: 17.5465%    
Year-to-date Change: 22.6%
LYEL Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add LYEL to Watchlist:       View:      Get Complete LYEL Trend Analysis ➞

Stock Chart of Maravai LifeSciences Holdings IncMRVI Maravai LifeSciences Holdings Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 640.96 Millions
Recent Price: 2.96    
Market Intelligence Score: 90
Day Percent Change: -5.57325%    
Day Change: -0.06
Week Change: 9.00735%    
Year-to-date Change: -46.0%
MRVI Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add MRVI to Watchlist:       View:      Get Complete MRVI Trend Analysis ➞

Stock Chart of Kaleido BioSciences, Inc.KLDO Kaleido BioSciences, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 229.185 Millions
Recent Price: 0.01    
Market Intelligence Score: 80
Day Percent Change: 9900%    
Day Change: -9999
Week Change: 9900%    
Year-to-date Change: 9,900.0%
KLDO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add KLDO to Watchlist:       View:      Get Complete KLDO Trend Analysis ➞

Stock Chart of I-Mab ADRIMAB I-Mab ADR
Sector: Health Care
SubSector: Biotechnology
MarketCap: 346.85 Millions
Recent Price: 4.14    
Market Intelligence Score: 80
Day Percent Change: 7.38342%    
Day Change: 0.19
Week Change: 16.4326%    
Year-to-date Change: 357.5%
IMAB Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add IMAB to Watchlist:       View:      Get Complete IMAB Trend Analysis ➞

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Performance: Year-to-date, Week and Day
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