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Best Biotech Stocks
Quick Read: Best Biotech Stocks List By Performances & Trends:
Daily, Weekly, Year-to-Date, Market Cap (Size) & Technical Trends
Best Biotech Stocks Views: Quick Browse View, Summary & Slide Show View

12Stocks.com: Investing in Biotech sector with Stocks
The following table helps investors and traders sort through current performance and trends (as measured by market intelligence score) of various stocks in the Biotech sector.

Quick View: Move mouse or cursor over stock symbol (ticker) to view short-term Technical chart and over stock name to view long term chart. Click on to add stock symbol to your watchlist and to view watchlist. Click on any ticker or stock name for detailed market intelligence report for that stock.

12Stocks.com Performance of Stocks in Biotech Sector

TickerStock NameWatchlistCategoryRecent PriceMarket Intelligence ScoreChange %YTD Change%
PGENPrecigen  Biotechnology1.78783.54%58.93%
GLSIGreenwich Life Biotechnology12.18780.54%8.46%
ARQTArcutis Bio Biotechnology14.777418.58%6.03%
MRSNMersana  Biotechnology6.30749.93%340.56%
MGNXMacroGenics  Biotechnology1.54744.33%-52.62%
ESPREsperion  Biotechnology1.87742.91%-15.00%
INCYyte  Biotechnology78.3974-0.60%13.49%
ALXOALX Oncology Biotechnology0.6874-4.97%-59.47%
VRCAVerrica  Biotechnology6.3574-46.69%807.14%
SMMTSummit  Biotechnology28.6673647.43%60.61%
XOMAXOMA  Biotechnology26.507380.51%0.84%
WVEWave Life Biotechnology8.09734.17%-34.60%
APLSApellis  Biotechnology24.37732.71%-23.63%
URGNUroGen Pharma Biotechnology17.75732.28%66.62%
RIGLRigel  Biotechnology31.70731.88%88.47%
SNDXSyndax  Biotechnology12.48731.48%-5.60%
FOLDAmicus  Biotechnology6.76730.90%-28.24%
PROKProKidney  Biotechnology2.59730.63%53.25%
KNSAKiniksa  Biotechnology32.15730.43%62.54%
BMRNBioMarin  Biotechnology57.3373-0.04%-12.78%
PLRXPliant  Biotechnology1.6673-1.32%-87.40%
IMNMImmunome  Biotechnology9.6973-1.34%-8.76%
AUPHAurinia  Biotechnology11.3773-30.38%26.61%
PRTAProthena  Biotechnology7.6973-64.38%-44.48%
APLTApplied  Biotechnology0.4371270.13%-50.29%
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Detailed Overview of Biotech Stocks
Biotech Technical Overview, Leaders & Laggards, Top Biotech ETF Funds & Detailed Biotech Stocks List, Charts, Trends & More

Biotech Sector: Technical Analysis, Trends & YTD Performance
Biotech sector, as represented by XBI, an exchange-traded fund [ETF] that holds basket of Biotech stocks (e.g, Amgen, Celgene) is down by % and is currently underperforming the overall market by -8.39% year-to-date. Below is a quick view of Technical charts and trends:

Weekly Chart

Daily Chart
Overall Trend Score:
YTD Performance: %
**Trend Scores & Views Are Only For Educational Purposes And Not For Investing


12Stocks.com: Top Performing Biotech Sector Stocks
Hot Biotech Stocks of 2025 We try to spot trends by analyzing the performances of various stocks or components within Biotech sector and try to find best performing stocks. The movers and shakers. The winners and losers.

The top performing Biotech sector stocks year to date are
Lyra [3146%] Nektar [2380%] Lyell Immunopharma[1616%]
Verrica [807%] RAPT [521%] Mersana [341%]
Generation Bio[287%] Galectin [222%] Tango [114%]
Adaptive nologies[104%] X4 [103%] Lineage Cell[96%]
View complete list of Biotech stocks by year-to-date performance

Now, more recently, over last week, the top performing Biotech sector stocks on the move are
Y-mAbs [87.9%] Alector [48.3%] Rigel [44.7%]
SIGA Technologies[38.7%] Esperion [33.6%] ALX Oncology[30.6%]
Avidity [28.9%] Novavax [27.6%] ANI [27.5%]
Syndax [25.1%] Ardelyx [20.3%] Puma nology[20.2%]
View complete list of Biotech stocks by weekly performance

Unfortunately not all Biotech stocks have done well this year. Investors of these stocks hope they have seen the worst and hope that these stocks are set to bounce back. The bearish stocks in this index year to date (YTD) are
Pliant [-87%] Sarepta [-85%] Acrivon [-79%]
IGM [-79%] Rocket [-77%] PepGen [-72%]
Iovance Bio[-71%] Entrada [-70%] Xencor [-69%]
Arvinas [-67%] Geron [-64%] Vaxcyte [-63%]
.
Investors can get enhanced performance by riding the current stock trends. Using complex algorithms, 12Stocks.com has come up with market intelligence scores (on 0-bearish to 100-bullish scale) to identify best trending stocks. Top trending Biotech stocks are
Precigen [78] Greenwich Life[78] Arcutis Bio[74]
Mersana [74] MacroGenics [74] Esperion [74]
yte [74] ALX Oncology[74] Verrica [74]
Summit [73] XOMA [73] Wave Life[73]
View complete list of Biotech stocks by 12Stocks.com trends

12Stocks.com: Investing in Biotech Sector using Exchange Traded Funds
The following table shows list of key exchange traded funds (ETF) that help investors track Biotech Index. For detailed view, check out our ETF Funds section of our website.

Quick View: Move mouse or cursor over ETF symbol (ticker) to view short-term Technical chart and over ETF name to view long term chart. Click on ticker or stock name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist.

12Stocks.com List of ETFs that track Biotech Index

TickerETF NameWatchlistRecent PriceMarket Intelligence ScoreChange %Week %Year-to-date %
IBBBiotechnology  132.046616.19-0.75-0.04%
IHFHealthcare Providers  42.62201.484.44-11.01%
CUREHealthcare Bull 3X 69.313333.21-2.7-24.66%
IXJGlobal Healthcare  83.35280.87-0.26-3.05%
ZBIOShort Biotech 14.63170-5.0678.63%
BBHBiotech  159.346913.23-1.991.51%
BIBBiotechnology  50.80812.26-0.430.52%
BISShort Biotech 15.7318-1.90.19-12.85%
 Market Intelligence Score (0-Bearish to 100-Bullish)
12Stocks.com: Charts, Trends, Fundamental Data and Performances of Biotech Stocks
We now take in-depth look at all Biotech stocks including charts, multi-period performances and overall trends (as measured by market intelligence score).

One can sort Biotech stocks (click link to choose) by Daily, Weekly and by Year-to-Date performances. Also, one can sort by size of the company or by market capitalization.
Select Your Default Chart Type:
Long Term Chart Daily Chart Weekly Chart 
Long Term Chart (Default)
Weekly Chart Example
Daily Chart Example
Click on stock symbol or name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist. Quick View: Move mouse or cursor over "Daily" to quickly view daily Technical stock chart and over "Weekly" to view weekly Technical stock chart.

Stock Chart of Precigen, Inc.PGEN Precigen, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 564.785 Millions
Recent Price: 1.78    
Market Intelligence Score: 78
Day Percent Change: 3.54%    
Day Change: 0.04
Week Change: 6.59%    
Year-to-date Change: 58.9%
PGEN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PGEN to Watchlist:       View:      Get Complete PGEN Trend Analysis ➞

Stock Chart of Greenwich LifeSciences, Inc.GLSI Greenwich LifeSciences, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 86487 Millions
Recent Price: 12.18    
Market Intelligence Score: 78
Day Percent Change: 0.54%    
Day Change: 0.08
Week Change: 9.83%    
Year-to-date Change: 8.5%
GLSI Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add GLSI to Watchlist:       View:      Get Complete GLSI Trend Analysis ➞

Stock Chart of Arcutis Biotherapeutics, Inc.ARQT Arcutis Biotherapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 12787 Millions
Recent Price: 14.77    
Market Intelligence Score: 74
Day Percent Change: 18.58%    
Day Change: 1.54
Week Change: 3.36%    
Year-to-date Change: 6.0%
ARQT Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ARQT to Watchlist:       View:      Get Complete ARQT Trend Analysis ➞

Stock Chart of Mersana Therapeutics, Inc.MRSN Mersana Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 224.385 Millions
Recent Price: 6.30    
Market Intelligence Score: 74
Day Percent Change: 9.93%    
Day Change: 0.14
Week Change: -4.55%    
Year-to-date Change: 340.6%
MRSN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add MRSN to Watchlist:       View:      Get Complete MRSN Trend Analysis ➞

Stock Chart of MacroGenics, Inc.MGNX MacroGenics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 262.785 Millions
Recent Price: 1.54    
Market Intelligence Score: 74
Day Percent Change: 4.33%    
Day Change: 0.15
Week Change: -2.53%    
Year-to-date Change: -52.6%
MGNX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add MGNX to Watchlist:       View:      Get Complete MGNX Trend Analysis ➞

Stock Chart of Esperion Therapeutics, Inc.ESPR Esperion Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1153.55 Millions
Recent Price: 1.87    
Market Intelligence Score: 74
Day Percent Change: 2.91%    
Day Change: 0.05
Week Change: 33.57%    
Year-to-date Change: -15.0%
ESPR Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ESPR to Watchlist:       View:      Get Complete ESPR Trend Analysis ➞

Stock Chart of Incyte CorporationINCY Incyte Corporation
Sector: Health Care
SubSector: Biotechnology
MarketCap: 15343.2 Millions
Recent Price: 78.39    
Market Intelligence Score: 74
Day Percent Change: -0.6%    
Day Change: -0.39
Week Change: 3.7%    
Year-to-date Change: 13.5%
INCY Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add INCY to Watchlist:       View:      Get Complete INCY Trend Analysis ➞

Stock Chart of ALX Oncology Holdings Inc.ALXO ALX Oncology Holdings Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 41787 Millions
Recent Price: 0.68    
Market Intelligence Score: 74
Day Percent Change: -4.97%    
Day Change: -0.13
Week Change: 30.63%    
Year-to-date Change: -59.5%
ALXO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ALXO to Watchlist:       View:      Get Complete ALXO Trend Analysis ➞

Stock Chart of Verrica Pharmaceuticals Inc.VRCA Verrica Pharmaceuticals Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 289.585 Millions
Recent Price: 6.35    
Market Intelligence Score: 74
Day Percent Change: -46.69%    
Day Change: -2.47
Week Change: 12.59%    
Year-to-date Change: 807.1%
VRCA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add VRCA to Watchlist:       View:      Get Complete VRCA Trend Analysis ➞

Stock Chart of Summit Therapeutics plcSMMT Summit Therapeutics plc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 156.985 Millions
Recent Price: 28.66    
Market Intelligence Score: 73
Day Percent Change: 647.43%    
Day Change: 11.33
Week Change: 5.87%    
Year-to-date Change: 60.6%
SMMT Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add SMMT to Watchlist:       View:      Get Complete SMMT Trend Analysis ➞

Stock Chart of XOMA CorporationXOMA XOMA Corporation
Sector: Health Care
SubSector: Biotechnology
MarketCap: 174.885 Millions
Recent Price: 26.50    
Market Intelligence Score: 73
Day Percent Change: 80.51%    
Day Change: 12.6
Week Change: 6.98%    
Year-to-date Change: 0.8%
XOMA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add XOMA to Watchlist:       View:      Get Complete XOMA Trend Analysis ➞

Stock Chart of Wave Life Sciences Ltd.WVE Wave Life Sciences Ltd.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 452.785 Millions
Recent Price: 8.09    
Market Intelligence Score: 73
Day Percent Change: 4.17%    
Day Change: 0.23
Week Change: -6.26%    
Year-to-date Change: -34.6%
WVE Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add WVE to Watchlist:       View:      Get Complete WVE Trend Analysis ➞

Stock Chart of Apellis Pharmaceuticals, Inc.APLS Apellis Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 2030.95 Millions
Recent Price: 24.37    
Market Intelligence Score: 73
Day Percent Change: 2.71%    
Day Change: 1.06
Week Change: 6.19%    
Year-to-date Change: -23.6%
APLS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add APLS to Watchlist:       View:      Get Complete APLS Trend Analysis ➞

Stock Chart of UroGen Pharma Ltd.URGN UroGen Pharma Ltd.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 373.485 Millions
Recent Price: 17.75    
Market Intelligence Score: 73
Day Percent Change: 2.28%    
Day Change: 0.33
Week Change: -8.53%    
Year-to-date Change: 66.6%
URGN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add URGN to Watchlist:       View:      Get Complete URGN Trend Analysis ➞

Stock Chart of Rigel Pharmaceuticals, Inc.RIGL Rigel Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 256.585 Millions
Recent Price: 31.70    
Market Intelligence Score: 73
Day Percent Change: 1.88%    
Day Change: 0.23
Week Change: 44.68%    
Year-to-date Change: 88.5%
RIGL Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add RIGL to Watchlist:       View:      Get Complete RIGL Trend Analysis ➞

Stock Chart of Syndax Pharmaceuticals, Inc.SNDX Syndax Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 365.985 Millions
Recent Price: 12.48    
Market Intelligence Score: 73
Day Percent Change: 1.48%    
Day Change: 0.3
Week Change: 25.05%    
Year-to-date Change: -5.6%
SNDX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add SNDX to Watchlist:       View:      Get Complete SNDX Trend Analysis ➞

Stock Chart of Amicus Therapeutics, Inc.FOLD Amicus Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 2676.75 Millions
Recent Price: 6.76    
Market Intelligence Score: 73
Day Percent Change: 0.9%    
Day Change: 0.11
Week Change: 6.96%    
Year-to-date Change: -28.2%
FOLD Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add FOLD to Watchlist:       View:      Get Complete FOLD Trend Analysis ➞

Stock Chart of ProKidney Corp.PROK ProKidney Corp.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 2470 Millions
Recent Price: 2.59    
Market Intelligence Score: 73
Day Percent Change: 0.63%    
Day Change: 0.02
Week Change: -8.16%    
Year-to-date Change: 53.3%
PROK Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PROK to Watchlist:       View:      Get Complete PROK Trend Analysis ➞

Stock Chart of Kiniksa Pharmaceuticals, Ltd.KNSA Kiniksa Pharmaceuticals, Ltd.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 780.285 Millions
Recent Price: 32.15    
Market Intelligence Score: 73
Day Percent Change: 0.43%    
Day Change: 0.08
Week Change: 0.53%    
Year-to-date Change: 62.5%
KNSA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add KNSA to Watchlist:       View:      Get Complete KNSA Trend Analysis ➞

Stock Chart of BioMarin Pharmaceutical Inc.BMRN BioMarin Pharmaceutical Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 14887.5 Millions
Recent Price: 57.33    
Market Intelligence Score: 73
Day Percent Change: -0.04%    
Day Change: -0.04
Week Change: -1.39%    
Year-to-date Change: -12.8%
BMRN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add BMRN to Watchlist:       View:      Get Complete BMRN Trend Analysis ➞

Stock Chart of Pliant Therapeutics, Inc.PLRX Pliant Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 96487 Millions
Recent Price: 1.66    
Market Intelligence Score: 73
Day Percent Change: -1.32%    
Day Change: -0.18
Week Change: 5.06%    
Year-to-date Change: -87.4%
PLRX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PLRX to Watchlist:       View:      Get Complete PLRX Trend Analysis ➞

Stock Chart of Immunome, Inc.IMNM Immunome, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 12487 Millions
Recent Price: 9.69    
Market Intelligence Score: 73
Day Percent Change: -1.34%    
Day Change: -0.21
Week Change: -8.5%    
Year-to-date Change: -8.8%
IMNM Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add IMNM to Watchlist:       View:      Get Complete IMNM Trend Analysis ➞

Stock Chart of Aurinia Pharmaceuticals Inc.AUPH Aurinia Pharmaceuticals Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 1319.75 Millions
Recent Price: 11.37    
Market Intelligence Score: 73
Day Percent Change: -30.38%    
Day Change: -2.95
Week Change: 8.39%    
Year-to-date Change: 26.6%
AUPH Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add AUPH to Watchlist:       View:      Get Complete AUPH Trend Analysis ➞

Stock Chart of Prothena Corporation plcPRTA Prothena Corporation plc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 357.985 Millions
Recent Price: 7.69    
Market Intelligence Score: 73
Day Percent Change: -64.38%    
Day Change: -39.24
Week Change: 12.92%    
Year-to-date Change: -44.5%
PRTA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PRTA to Watchlist:       View:      Get Complete PRTA Trend Analysis ➞

Stock Chart of Applied Therapeutics, Inc.APLT Applied Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 641.285 Millions
Recent Price: 0.43    
Market Intelligence Score: 71
Day Percent Change: 270.13%    
Day Change: 4.16
Week Change: -3.43%    
Year-to-date Change: -50.3%
APLT Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add APLT to Watchlist:       View:      Get Complete APLT Trend Analysis ➞

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Performance: Year-to-date, Week and Day
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Biotech Stocks With Best Up Trends [0-bearish to 100-bullish]:
Precigen [78], Greenwich Life[78], Arcutis Bio[74], Mersana [74], MacroGenics [74], Esperion [74], yte [74], ALX Oncology[74], Verrica [74], Summit [73], XOMA [73]

Best Biotech Stocks Year-to-Date:
Lyra [3146.12%], Nektar [2379.57%], Lyell Immunopharma[1615.63%], Verrica [807.14%], RAPT [520.89%], Mersana [340.56%], Generation Bio[286.79%], Galectin [221.71%], Tango [113.92%], Adaptive nologies[103.5%], X4 [103%]

Best Biotech Stocks This Week:
Y-mAbs [87.86%], Alector [48.28%], Rigel [44.68%], SIGA Technologies[38.7%], Esperion [33.57%], ALX Oncology[30.63%], Avidity [28.87%], Novavax [27.59%], ANI [27.45%], Syndax [25.05%], Ardelyx [20.32%]

Best Biotech Stocks Daily:
Corbus [827.02%], Summit [647.43%], Applied [270.13%], Crinetics [209.71%], TG [153.47%], Arbutus Biopharma[91.63%], XOMA [80.51%], Cytokinetics [79.41%], Iovance Bio[66.25%], Novavax [65.84%], Mirum [64.05%]


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