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Best Biotech Stocks

Quick Read: Best Biotech Stocks List By Performances & Trends:
Daily, Weekly, Year-to-Date, Market Cap (Size) & Technical Trends
Best Biotech Stocks Views: Quick Browse View, Summary & Slide Show View

12Stocks.com Biotech Stocks Performances & Trends Daily
October 3, 2025 - All trends (long term, mid-term and short term) for Biotech sector looks good.

The overall market intelligence score is 100 (0-bearish to 100-bullish) which puts Biotech sector in short term bullish trend.

The market intelligence score from previous trading session is 90 and an improvement of trend continues.

 Year To Date Performance: 12.1001 %
 Weekly Performance: 5.2853 %
 Daily Performance: 1.18355 %
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Biotech Sector Trend
100 / 100
Here are the market intelligence trend scores of the most requested Biotech stocks at 12Stocks.com (click stock name for detailed review):

12Stocks.com: Investing in Biotech sector with Stocks
The following table helps investors and traders sort through current performance and trends (as measured by market intelligence score) of various stocks in the Biotech sector.

Quick View: Move mouse or cursor over stock symbol (ticker) to view short-term Technical chart and over stock name to view long term chart. Click on to add stock symbol to your watchlist and to view watchlist. Click on any ticker or stock name for detailed market intelligence report for that stock.

12Stocks.com Performance of Stocks in Biotech Sector

TickerStock NameWatchlistCategoryRecent PriceMarket Intelligence ScoreChange %YTD Change%
KRYSKrystal  Biotechnology181.691001.16%16.10%
XLRNAcceleron Pharma Biotechnology5.52301.47%0.00%
PCVXVaxcyte  Biotechnology40.151005.57%-51.80%
ACADAcadia  Biotechnology21.38200.66%14.58%
ACLXArcellx  Biotechnology82.24560.36%-6.42%
ADMAAdma Biologics Biotechnology14.530-3.46%-19.14%
ARWRArrowhead  Biotechnology34.5990-1.20%76.03%
MIRMMirum  Biotechnology71.7530-1.71%70.67%
MLTXMoonLake Immuno Biotechnology7.46305.67%-86.07%
PTGXProtagonist  Biotechnology65.03501.61%66.83%
SLNOSoleno  Biotechnology57.9830-3.56%26.84%
AKROAkero  Biotechnology46.4130-0.30%65.28%
APLSApellis  Biotechnology23.13600.13%-30.25%
ZLABZai Lab Biotechnology33.8570-1.71%36.44%
BLUEbluebird bio Biotechnology4.97400.00%-42.81%
CRNXCrinetics  Biotechnology41.5060-0.26%-19.50%
MRTXMirati  Biotechnology4.55301.11%0.00%
GBTGlobal Blood Biotechnology19.8700.91%0.00%
LGNDLigand  Biotechnology180.121000.58%66.13%
ALLKAllakos  Biotechnology0.3350-0.06%-73.46%
BPMCBlueprint Medicines Biotechnology129.46600.14%48.46%
KYMRKymera  Biotechnology56.00602.45%36.95%
RAREUltragenyx  Biotechnology30.911003.07%-24.88%
NAMSNewAmsterdam Pharma Biotechnology30.761004.77%18.49%
VKTXViking  Biotechnology27.88801.86%-32.20%
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Performance: Year-to-date, Week and Day
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Detailed Overview of Biotech Stocks
Biotech Technical Overview, Leaders & Laggards, Top Biotech ETF Funds & Detailed Biotech Stocks List, Charts, Trends & More

Biotech Sector: Technical Analysis, Trends & YTD Performance
Biotech sector, as represented by XBI, an exchange-traded fund [ETF] that holds basket of Biotech stocks (e.g, Amgen, Celgene) is up by 12.1001% and is currently underperforming the overall market by -2.6578% year-to-date. Below is a quick view of Technical charts and trends:

XBI Weekly Chart
Long Term Trend: Very Good
Medium Term Trend: Very Good

XBI Daily Chart
Short Term Trend: Very Good
Overall Trend Score: 100
YTD Performance: 12.1001%
**Trend Scores & Views Are Only For Educational Purposes And Not For Investing


12Stocks.com: Top Performing Biotech Sector Stocks
Hot Biotech Stocks of 2025 We try to spot trends by analyzing the performances of various stocks or components within Biotech sector and try to find best performing stocks. The movers and shakers. The winners and losers.

The top performing Biotech sector stocks year to date are
Vor Biopharma[3175%] Nanobiotix ADR[581%] I-Mab ADR[358%]
Monopar [337%] Nektar [320%] DBV Technologies[277%]
Celcuity [276%] Galectin [263%] Cidara [261%]
Lineage Cell[234%] ATAI Life[221%]
View complete list of Biotech stocks by year-to-date performance

Now, more recently, over last week, the top performing Biotech sector stocks on the move are
Athersys [193287%] VBI Vaccines[86898.5%] ContraFect [47677.8%]
Clovis Oncology[39610.5%] NanoString Technologies[17224.7%] Neptune Wellness[14100%]
Achillion [10033.3%] Nymox [8258.5%] Epizyme [5739.5%]
Portola [4717.6%] Strongbridge Biopharma[3417.5%]
View complete list of Biotech stocks by weekly performance

Unfortunately not all Biotech stocks have done well this year. Investors of these stocks hope they have seen the worst and hope that these stocks are set to bounce back. The bearish stocks in this index year to date (YTD) are
Vaxxinity [-100%] Petros [-100%] Translate Bio[-95%]
Palatin Technologies[-93%] Syros [-91%] Pliant [-89%]
Affimed N.V[-87%] MoonLake Immuno[-86%] Unity nology[-86%]
Sarepta [-82%] Kala Bio[-80%] IGM [-80%]
.
Investors can get enhanced performance by riding the current stock trends. Using complex algorithms, 12Stocks.com has come up with market intelligence scores (on 0-bearish to 100-bullish scale) to identify best trending stocks. Top trending Biotech stocks are
Taysha Gene[100] DBV Technologies[100] Valneva SE[100]
Prime Medicine[100] AlloVir [100] Sarepta [100]
Monopar [100] Cara [100] Absci Corp[100]
Spruce [100] Cabaletta Bio[100] Compugen [100]
View complete list of Biotech stocks by 12Stocks.com trends

12Stocks.com: Investing in Biotech Sector using Exchange Traded Funds
The following table shows list of key exchange traded funds (ETF) that help investors track Biotech Index. For detailed view, check out our ETF Funds section of our website.

Quick View: Move mouse or cursor over ETF symbol (ticker) to view short-term Technical chart and over ETF name to view long term chart. Click on ticker or stock name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist.

12Stocks.com List of ETFs that track Biotech Index

TickerETF NameWatchlistRecent PriceMarket Intelligence ScoreChange %Week %Year-to-date %
UBIOBiotechnology  73.3480-0.0681292260.7480%
HCRFEdge Multifactor 67.142309999NA
SICKHealthcare Bear 3X 37.903609999NA
LABSBiotech Bear 1X 24.185609999NA
BTECPrincipal Healthcare Innovators 39.493001.023280%
 Market Intelligence Score (0-Bearish to 100-Bullish)
12Stocks.com: Charts, Trends, Fundamental Data and Performances of Biotech Stocks
We now take in-depth look at all Biotech stocks including charts, multi-period performances and overall trends (as measured by market intelligence score).

One can sort Biotech stocks (click link to choose) by Daily, Weekly and by Year-to-Date performances. Also, one can sort by size of the company or by market capitalization.
Select Your Default Chart Type:
Long Term Chart Daily Chart Weekly Chart 
Long Term Chart (Default)
Weekly Chart Example
Daily Chart Example
Click on stock symbol or name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist. Quick View: Move mouse or cursor over "Daily" to quickly view daily Technical stock chart and over "Weekly" to view weekly Technical stock chart.

Stock Chart of Krystal Biotech IncKRYS Krystal Biotech Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 4349.26 Millions
Recent Price: 181.69    
Market Intelligence Score: 100
Day Percent Change: 1.15806%    
Day Change: -0.16
Week Change: 12.1543%    
Year-to-date Change: 16.1%
KRYS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add KRYS to Watchlist:       View:      Get Complete KRYS Trend Analysis ➞

Stock Chart of Acceleron Pharma Inc.XLRN Acceleron Pharma Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 4338.75 Millions
Recent Price: 5.52    
Market Intelligence Score: 30
Day Percent Change: 1.47059%    
Day Change: -9999
Week Change: -96.9119%    
Year-to-date Change: 0.0%
XLRN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add XLRN to Watchlist:       View:      Get Complete XLRN Trend Analysis ➞

Stock Chart of Vaxcyte IncPCVX Vaxcyte Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 4286.77 Millions
Recent Price: 40.15    
Market Intelligence Score: 100
Day Percent Change: 5.57455%    
Day Change: 0.65
Week Change: 22.3339%    
Year-to-date Change: -51.8%
PCVX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PCVX to Watchlist:       View:      Get Complete PCVX Trend Analysis ➞

Stock Chart of Acadia Pharmaceuticals IncACAD Acadia Pharmaceuticals Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 4261.67 Millions
Recent Price: 21.38    
Market Intelligence Score: 20
Day Percent Change: 0.659134%    
Day Change: -0.16
Week Change: 0.56444%    
Year-to-date Change: 14.6%
ACAD Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ACAD to Watchlist:       View:      Get Complete ACAD Trend Analysis ➞

Stock Chart of Arcellx IncACLX Arcellx Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 4027.43 Millions
Recent Price: 82.24    
Market Intelligence Score: 56
Day Percent Change: 0.36%    
Day Change: 0.26
Week Change: -0.13%    
Year-to-date Change: -6.4%
ACLX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ACLX to Watchlist:       View:      Get Complete ACLX Trend Analysis ➞

Stock Chart of Adma Biologics IncADMA Adma Biologics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 4025.7 Millions
Recent Price: 14.53    
Market Intelligence Score: 0
Day Percent Change: -3.45515%    
Day Change: -0.2
Week Change: -7.21584%    
Year-to-date Change: -19.1%
ADMA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ADMA to Watchlist:       View:      Get Complete ADMA Trend Analysis ➞

Stock Chart of Arrowhead Pharmaceuticals IncARWR Arrowhead Pharmaceuticals Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 4019.84 Millions
Recent Price: 34.59    
Market Intelligence Score: 90
Day Percent Change: -1.19966%    
Day Change: 0.55
Week Change: 5.36095%    
Year-to-date Change: 76.0%
ARWR Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ARWR to Watchlist:       View:      Get Complete ARWR Trend Analysis ➞

Stock Chart of Mirum Pharmaceuticals IncMIRM Mirum Pharmaceuticals Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 3821.08 Millions
Recent Price: 71.75    
Market Intelligence Score: 30
Day Percent Change: -1.71233%    
Day Change: 2.35
Week Change: -3.38002%    
Year-to-date Change: 70.7%
MIRM Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add MIRM to Watchlist:       View:      Get Complete MIRM Trend Analysis ➞

Stock Chart of MoonLake ImmunotherapeuticsMLTX MoonLake Immunotherapeutics
Sector: Health Care
SubSector: Biotechnology
MarketCap: 3817.87 Millions
Recent Price: 7.46    
Market Intelligence Score: 30
Day Percent Change: 5.66572%    
Day Change: 0.03
Week Change: -85.8013%    
Year-to-date Change: -86.1%
MLTX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add MLTX to Watchlist:       View:      Get Complete MLTX Trend Analysis ➞

Stock Chart of Protagonist Therapeutics IncPTGX Protagonist Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 3765.65 Millions
Recent Price: 65.03    
Market Intelligence Score: 50
Day Percent Change: 1.60938%    
Day Change: -0.19
Week Change: -1.395%    
Year-to-date Change: 66.8%
PTGX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PTGX to Watchlist:       View:      Get Complete PTGX Trend Analysis ➞

Stock Chart of Soleno Therapeutics IncSLNO Soleno Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 3707.93 Millions
Recent Price: 57.98    
Market Intelligence Score: 30
Day Percent Change: -3.55955%    
Day Change: 0.86
Week Change: -10.1085%    
Year-to-date Change: 26.8%
SLNO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add SLNO to Watchlist:       View:      Get Complete SLNO Trend Analysis ➞

Stock Chart of Akero Therapeutics IncAKRO Akero Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 3577.11 Millions
Recent Price: 46.41    
Market Intelligence Score: 30
Day Percent Change: -0.300752%    
Day Change: 0.34
Week Change: -2.21239%    
Year-to-date Change: 65.3%
AKRO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add AKRO to Watchlist:       View:      Get Complete AKRO Trend Analysis ➞

Stock Chart of Apellis Pharmaceuticals IncAPLS Apellis Pharmaceuticals Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 3552.54 Millions
Recent Price: 23.13    
Market Intelligence Score: 60
Day Percent Change: 0.12987%    
Day Change: -0.16
Week Change: 1.62566%    
Year-to-date Change: -30.2%
APLS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add APLS to Watchlist:       View:      Get Complete APLS Trend Analysis ➞

Stock Chart of Zai Lab Limited ADRZLAB Zai Lab Limited ADR
Sector: Health Care
SubSector: Biotechnology
MarketCap: 3422.67 Millions
Recent Price: 33.85    
Market Intelligence Score: 70
Day Percent Change: -1.71312%    
Day Change: 0.49
Week Change: 4.1859%    
Year-to-date Change: 36.4%
ZLAB Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ZLAB to Watchlist:       View:      Get Complete ZLAB Trend Analysis ➞

Stock Chart of bluebird bio, Inc.BLUE bluebird bio, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 3365.05 Millions
Recent Price: 4.97    
Market Intelligence Score: 40
Day Percent Change: 0%    
Day Change: -9999
Week Change: 0%    
Year-to-date Change: -42.8%
BLUE Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add BLUE to Watchlist:       View:      Get Complete BLUE Trend Analysis ➞

Stock Chart of Crinetics Pharmaceuticals IncCRNX Crinetics Pharmaceuticals Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 3353.61 Millions
Recent Price: 41.50    
Market Intelligence Score: 60
Day Percent Change: -0.26436%    
Day Change: 0.31
Week Change: 17.9648%    
Year-to-date Change: -19.5%
CRNX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CRNX to Watchlist:       View:      Get Complete CRNX Trend Analysis ➞

Stock Chart of Mirati Therapeutics, Inc.MRTX Mirati Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 3338.85 Millions
Recent Price: 4.55    
Market Intelligence Score: 30
Day Percent Change: 1.11111%    
Day Change: -9999
Week Change: -92.2619%    
Year-to-date Change: 0.0%
MRTX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add MRTX to Watchlist:       View:      Get Complete MRTX Trend Analysis ➞

Stock Chart of Global Blood Therapeutics, Inc.GBT Global Blood Therapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 3276.75 Millions
Recent Price: 19.87    
Market Intelligence Score: 0
Day Percent Change: 0.91417%    
Day Change: -9999
Week Change: -70.9885%    
Year-to-date Change: 0.0%
GBT Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add GBT to Watchlist:       View:      Get Complete GBT Trend Analysis ➞

Stock Chart of Ligand Pharmaceuticals, IncLGND Ligand Pharmaceuticals, Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 3267.73 Millions
Recent Price: 180.12    
Market Intelligence Score: 100
Day Percent Change: 0.583554%    
Day Change: 2.06
Week Change: 6.60511%    
Year-to-date Change: 66.1%
LGND Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add LGND to Watchlist:       View:      Get Complete LGND Trend Analysis ➞

Stock Chart of Allakos Inc.ALLK Allakos Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 3233.55 Millions
Recent Price: 0.33    
Market Intelligence Score: 50
Day Percent Change: -0.0607349%    
Day Change: -9999
Week Change: 0.42722%    
Year-to-date Change: -73.5%
ALLK Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ALLK to Watchlist:       View:      Get Complete ALLK Trend Analysis ➞

Stock Chart of Blueprint Medicines CorporationBPMC Blueprint Medicines Corporation
Sector: Health Care
SubSector: Biotechnology
MarketCap: 3113.55 Millions
Recent Price: 129.46    
Market Intelligence Score: 60
Day Percent Change: 0.139233%    
Day Change: -9999
Week Change: 0.707896%    
Year-to-date Change: 48.5%
BPMC Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add BPMC to Watchlist:       View:      Get Complete BPMC Trend Analysis ➞

Stock Chart of Kymera Therapeutics IncKYMR Kymera Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 3110.86 Millions
Recent Price: 56.00    
Market Intelligence Score: 60
Day Percent Change: 2.45152%    
Day Change: 0.24
Week Change: 6.66667%    
Year-to-date Change: 37.0%
KYMR Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add KYMR to Watchlist:       View:      Get Complete KYMR Trend Analysis ➞

Stock Chart of Ultragenyx Pharmaceutical IncRARE Ultragenyx Pharmaceutical Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 3066.55 Millions
Recent Price: 30.91    
Market Intelligence Score: 100
Day Percent Change: 3.06769%    
Day Change: 0.75
Week Change: 7.47566%    
Year-to-date Change: -24.9%
RARE Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add RARE to Watchlist:       View:      Get Complete RARE Trend Analysis ➞

Stock Chart of NewAmsterdam Pharma Company NVNAMS NewAmsterdam Pharma Company NV
Sector: Health Care
SubSector: Biotechnology
MarketCap: 3040.97 Millions
Recent Price: 30.76    
Market Intelligence Score: 100
Day Percent Change: 4.76839%    
Day Change: 0.12
Week Change: 14.9477%    
Year-to-date Change: 18.5%
NAMS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add NAMS to Watchlist:       View:      Get Complete NAMS Trend Analysis ➞

Stock Chart of Viking Therapeutics IncVKTX Viking Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 3033.77 Millions
Recent Price: 27.88    
Market Intelligence Score: 80
Day Percent Change: 1.86335%    
Day Change: -0.03
Week Change: 4.69395%    
Year-to-date Change: -32.2%
VKTX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add VKTX to Watchlist:       View:      Get Complete VKTX Trend Analysis ➞

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