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Best Biotech Stocks

Quick Read: Best Biotech Stocks List By Performances & Trends:
Daily, Weekly, Year-to-Date, Market Cap (Size) & Technical Trends
Best Biotech Stocks Views: Quick Browse View, Summary & Slide Show View

12Stocks.com Biotech Stocks Performances & Trends Daily
September 18, 2025 - Although long and mid term trends for Biotech sector looks good, the short term trends are deteriorating.

The overall market intelligence score is 60 (0-bearish to 100-bullish) which puts Biotech sector in short term neutral to bullish trend.

The market intelligence score from previous trading session is 70 and a deterioration of trend continues.

 Year To Date Performance: 2.46251 %
 Weekly Performance: -1.27395 %
 Daily Performance: 0.0320034 %
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Biotech Sector Trend
60 / 100
Here are the market intelligence trend scores of the most requested Biotech stocks at 12Stocks.com (click stock name for detailed review):

12Stocks.com: Investing in Biotech sector with Stocks
The following table helps investors and traders sort through current performance and trends (as measured by market intelligence score) of various stocks in the Biotech sector.

Quick View: Move mouse or cursor over stock symbol (ticker) to view short-term Technical chart and over stock name to view long term chart. Click on to add stock symbol to your watchlist and to view watchlist. Click on any ticker or stock name for detailed market intelligence report for that stock.

12Stocks.com Performance of Stocks in Biotech Sector

TickerStock NameWatchlistCategoryRecent PriceMarket Intelligence ScoreChange %YTD Change%
PPHMPeregrine  Biotechnology4.22100.00%0.00%
BDTXBlack Diamond Biotechnology3.1650-0.32%47.66%
BFRABiofrontera AG Biotechnology1.9410-5.37%0.00%
EIGREiger Bio Biotechnology0.57501.79%0.00%
SGMOSangamo  Biotechnology0.5120-0.29%-54.63%
IMDZImmune Design Biotechnology7.07300.00%0.00%
AFMDAffimed N.V Biotechnology0.1820-34.95%-86.56%
KINKindred  Biotechnology43.9270-0.45%0.00%
NKTXNkarta  Biotechnology1.9120-2.05%-23.60%
PBMDPrima Biomed Biotechnology1.71100.00%0.00%
CHMAChiasma  Biotechnology0.3500.00%0.00%
ARLZAralez  Biotechnology30.6260-0.26%0.00%
CABACabaletta Bio Biotechnology1.9290-3.52%-17.60%
MISTMilestone  Biotechnology1.9450-0.51%-10.60%
PRTKParatek  Biotechnology58.01903.83%0.00%
PIRSPieris  Biotechnology12.030-27.16%0.00%
THTXTheratechnologies  Biotechnology3.31800.46%79.89%
CHRSCoherus Oncology Biotechnology1.3580-0.74%-3.57%
GLSIGreenwich Life Biotechnology11.1520-1.06%-5.03%
ASTAsterias Bio Biotechnology14.23400.49%0.00%
OBIOOrchestra BioMed Biotechnology2.4610-2.77%-54.28%
INOInovio  Biotechnology2.1830-4.39%19.78%
ACHVAchieve Life Biotechnology2.9640-3.90%-19.78%
NYMXNymox  Biotechnology44.30700.16%0.00%
ZURAZura Bio Biotechnology1.905113.71%-20.40%
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Performance: Year-to-date, Week and Day
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Detailed Overview of Biotech Stocks
Biotech Technical Overview, Leaders & Laggards, Top Biotech ETF Funds & Detailed Biotech Stocks List, Charts, Trends & More

Biotech Sector: Technical Analysis, Trends & YTD Performance
Biotech sector, as represented by XBI, an exchange-traded fund [ETF] that holds basket of Biotech stocks (e.g, Amgen, Celgene) is up by 2.46251% and is currently underperforming the overall market by -10.68429% year-to-date. Below is a quick view of Technical charts and trends:

XBI Weekly Chart
Long Term Trend: Very Good
Medium Term Trend: Very Good

XBI Daily Chart
Short Term Trend: Not Good
Overall Trend Score: 60
YTD Performance: 2.46251%
**Trend Scores & Views Are Only For Educational Purposes And Not For Investing


12Stocks.com: Top Performing Biotech Sector Stocks
Hot Biotech Stocks of 2025 We try to spot trends by analyzing the performances of various stocks or components within Biotech sector and try to find best performing stocks. The movers and shakers. The winners and losers.

The top performing Biotech sector stocks year to date are
Celcuity [316%] I-Mab ADR[307%] Galectin [292%]
Immuneering Corp[265%] Nektar [254%] Precigen [254%]
Nanobiotix ADR[252%] Gossamer Bio[208%] DBV Technologies[203%]
Monopar [200%] ATAI Life[194%]
View complete list of Biotech stocks by year-to-date performance

Now, more recently, over last week, the top performing Biotech sector stocks on the move are
Athersys [193287%] VBI Vaccines[86898.5%] ContraFect [47677.8%]
Clovis Oncology[39610.5%] NanoString Technologies[17224.7%] Neptune Wellness[14100%]
Achillion [10033.3%] Nymox [8258.5%] Epizyme [5739.5%]
Portola [4717.6%] Strongbridge Biopharma[3417.5%]
View complete list of Biotech stocks by weekly performance

Unfortunately not all Biotech stocks have done well this year. Investors of these stocks hope they have seen the worst and hope that these stocks are set to bounce back. The bearish stocks in this index year to date (YTD) are
Vaxxinity [-100%] Petros [-100%] Translate Bio[-95%]
Palatin Technologies[-93%] Syros [-91%] Pliant [-88%]
Affimed N.V[-87%] Sarepta [-86%] Unity nology[-86%]
IGM [-80%] Rocket [-76%] Allakos [-73%]
.
Investors can get enhanced performance by riding the current stock trends. Using complex algorithms, 12Stocks.com has come up with market intelligence scores (on 0-bearish to 100-bullish scale) to identify best trending stocks. Top trending Biotech stocks are
AlloVir [100] Monopar [100] Cara [100]
Corbus [100] Spruce [100] Ocugen [100]
Roivant [100] Xencor [100] Oncolytics [100]
Tango [100] Arcus [100] Regeneron [100]
View complete list of Biotech stocks by 12Stocks.com trends

12Stocks.com: Investing in Biotech Sector using Exchange Traded Funds
The following table shows list of key exchange traded funds (ETF) that help investors track Biotech Index. For detailed view, check out our ETF Funds section of our website.

Quick View: Move mouse or cursor over ETF symbol (ticker) to view short-term Technical chart and over ETF name to view long term chart. Click on ticker or stock name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist.

12Stocks.com List of ETFs that track Biotech Index

TickerETF NameWatchlistRecent PriceMarket Intelligence ScoreChange %Week %Year-to-date %
UBIOBiotechnology  73.3480-0.0681292260.7480%
HCRFEdge Multifactor 67.142309999NA
SICKHealthcare Bear 3X 37.903609999NA
LABSBiotech Bear 1X 24.185609999NA
BTECPrincipal Healthcare Innovators 39.493001.023280%
 Market Intelligence Score (0-Bearish to 100-Bullish)
12Stocks.com: Charts, Trends, Fundamental Data and Performances of Biotech Stocks
We now take in-depth look at all Biotech stocks including charts, multi-period performances and overall trends (as measured by market intelligence score).

One can sort Biotech stocks (click link to choose) by Daily, Weekly and by Year-to-Date performances. Also, one can sort by size of the company or by market capitalization.
Select Your Default Chart Type:
Long Term Chart Daily Chart Weekly Chart 
Long Term Chart (Default)
Weekly Chart Example
Daily Chart Example
Click on stock symbol or name for detailed view. Click on to add stock symbol to your watchlist and to view watchlist. Quick View: Move mouse or cursor over "Daily" to quickly view daily Technical stock chart and over "Weekly" to view weekly Technical stock chart.

Stock Chart of Peregrine Pharmaceuticals, Inc.PPHM Peregrine Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 168.51 Millions
Recent Price: 4.22    
Market Intelligence Score: 10
Day Percent Change: 0%    
Day Change: -9999
Week Change: 0%    
Year-to-date Change: 0.0%
PPHM Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PPHM to Watchlist:       View:      Get Complete PPHM Trend Analysis ➞

Stock Chart of Black Diamond Therapeutics IncBDTX Black Diamond Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 167.39 Millions
Recent Price: 3.16    
Market Intelligence Score: 50
Day Percent Change: -0.315457%    
Day Change: 0.11
Week Change: -2.76923%    
Year-to-date Change: 47.7%
BDTX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add BDTX to Watchlist:       View:      Get Complete BDTX Trend Analysis ➞

Stock Chart of Biofrontera AGBFRA Biofrontera AG
Sector: Health Care
SubSector: Biotechnology
MarketCap: 166.685 Millions
Recent Price: 1.94    
Market Intelligence Score: 10
Day Percent Change: -5.36585%    
Day Change: -9999
Week Change: -12.809%    
Year-to-date Change: 0.0%
BFRA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add BFRA to Watchlist:       View:      Get Complete BFRA Trend Analysis ➞

Stock Chart of Eiger BioPharmaceuticals, Inc.EIGR Eiger BioPharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 166.585 Millions
Recent Price: 0.57    
Market Intelligence Score: 50
Day Percent Change: 1.78571%    
Day Change: -9999
Week Change: -70%    
Year-to-date Change: 0.0%
EIGR Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add EIGR to Watchlist:       View:      Get Complete EIGR Trend Analysis ➞

Stock Chart of Sangamo Therapeutics IncSGMO Sangamo Therapeutics Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 165.1 Millions
Recent Price: 0.51    
Market Intelligence Score: 20
Day Percent Change: -0.291715%    
Day Change: 0.03
Week Change: -1.34693%    
Year-to-date Change: -54.6%
SGMO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add SGMO to Watchlist:       View:      Get Complete SGMO Trend Analysis ➞

Stock Chart of Immune Design Corp.IMDZ Immune Design Corp.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 162.8 Millions
Recent Price: 7.07    
Market Intelligence Score: 30
Day Percent Change: 0%    
Day Change: -9999
Week Change: -1.80556%    
Year-to-date Change: 0.0%
IMDZ Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add IMDZ to Watchlist:       View:      Get Complete IMDZ Trend Analysis ➞

Stock Chart of Affimed N.V.AFMD Affimed N.V.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 161.385 Millions
Recent Price: 0.18    
Market Intelligence Score: 20
Day Percent Change: -34.9462%    
Day Change: -9999
Week Change: -73.5036%    
Year-to-date Change: -86.6%
AFMD Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add AFMD to Watchlist:       View:      Get Complete AFMD Trend Analysis ➞

Stock Chart of Kindred Biosciences, Inc.KIN Kindred Biosciences, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 160.785 Millions
Recent Price: 43.92    
Market Intelligence Score: 70
Day Percent Change: -0.453309%    
Day Change: -9999
Week Change: 374.811%    
Year-to-date Change: 0.0%
KIN Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add KIN to Watchlist:       View:      Get Complete KIN Trend Analysis ➞

Stock Chart of Nkarta IncNKTX Nkarta Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 160.52 Millions
Recent Price: 1.91    
Market Intelligence Score: 20
Day Percent Change: -2.05128%    
Day Change: 0.06
Week Change: -7.72947%    
Year-to-date Change: -23.6%
NKTX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add NKTX to Watchlist:       View:      Get Complete NKTX Trend Analysis ➞

Stock Chart of Prima Biomed Ltd.PBMD Prima Biomed Ltd.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 160.51 Millions
Recent Price: 1.71    
Market Intelligence Score: 10
Day Percent Change: 0%    
Day Change: -9999
Week Change: 0%    
Year-to-date Change: 0.0%
PBMD Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PBMD to Watchlist:       View:      Get Complete PBMD Trend Analysis ➞

Stock Chart of Chiasma, Inc.CHMA Chiasma, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 158.985 Millions
Recent Price: 0.35    
Market Intelligence Score: 0
Day Percent Change: 0%    
Day Change: -9999
Week Change: -90.6915%    
Year-to-date Change: 0.0%
CHMA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CHMA to Watchlist:       View:      Get Complete CHMA Trend Analysis ➞

Stock Chart of Aralez Pharmaceuticals Inc.ARLZ Aralez Pharmaceuticals Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 155.5 Millions
Recent Price: 30.62    
Market Intelligence Score: 60
Day Percent Change: -0.260586%    
Day Change: -9999
Week Change: 3.16712%    
Year-to-date Change: 0.0%
ARLZ Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ARLZ to Watchlist:       View:      Get Complete ARLZ Trend Analysis ➞

Stock Chart of Cabaletta Bio IncCABA Cabaletta Bio Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 155.49 Millions
Recent Price: 1.92    
Market Intelligence Score: 90
Day Percent Change: -3.51759%    
Day Change: 0.02
Week Change: 17.0732%    
Year-to-date Change: -17.6%
CABA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CABA to Watchlist:       View:      Get Complete CABA Trend Analysis ➞

Stock Chart of Milestone Pharmaceuticals IncMIST Milestone Pharmaceuticals Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 152.99 Millions
Recent Price: 1.94    
Market Intelligence Score: 50
Day Percent Change: -0.512821%    
Day Change: 0.07
Week Change: 12.7907%    
Year-to-date Change: -10.6%
MIST Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add MIST to Watchlist:       View:      Get Complete MIST Trend Analysis ➞

Stock Chart of Paratek Pharmaceuticals, Inc.PRTK Paratek Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 151.185 Millions
Recent Price: 58.01    
Market Intelligence Score: 90
Day Percent Change: 3.83032%    
Day Change: -9999
Week Change: 2501.35%    
Year-to-date Change: 0.0%
PRTK Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PRTK to Watchlist:       View:      Get Complete PRTK Trend Analysis ➞

Stock Chart of Pieris Pharmaceuticals, Inc.PIRS Pieris Pharmaceuticals, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 150.785 Millions
Recent Price: 12.03    
Market Intelligence Score: 0
Day Percent Change: -27.1565%    
Day Change: -9999
Week Change: -26.4694%    
Year-to-date Change: 0.0%
PIRS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add PIRS to Watchlist:       View:      Get Complete PIRS Trend Analysis ➞

Stock Chart of Theratechnologies IncTHTX Theratechnologies Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 150.35 Millions
Recent Price: 3.31    
Market Intelligence Score: 80
Day Percent Change: 0.455235%    
Day Change: 0
Week Change: 1.22324%    
Year-to-date Change: 79.9%
THTX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add THTX to Watchlist:       View:      Get Complete THTX Trend Analysis ➞

Stock Chart of Coherus Oncology IncCHRS Coherus Oncology Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 149.93 Millions
Recent Price: 1.35    
Market Intelligence Score: 80
Day Percent Change: -0.735294%    
Day Change: 0.06
Week Change: 0%    
Year-to-date Change: -3.6%
CHRS Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add CHRS to Watchlist:       View:      Get Complete CHRS Trend Analysis ➞

Stock Chart of Greenwich LifeSciences IncGLSI Greenwich LifeSciences Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 148.98 Millions
Recent Price: 11.15    
Market Intelligence Score: 20
Day Percent Change: -1.06477%    
Day Change: -0.09
Week Change: 1.36364%    
Year-to-date Change: -5.0%
GLSI Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add GLSI to Watchlist:       View:      Get Complete GLSI Trend Analysis ➞

Stock Chart of Asterias Biotherapeutics, Inc.AST Asterias Biotherapeutics, Inc.
Sector: Health Care
SubSector: Biotechnology
MarketCap: 148.51 Millions
Recent Price: 14.23    
Market Intelligence Score: 40
Day Percent Change: 0.49435%    
Day Change: -9999
Week Change: -19.6045%    
Year-to-date Change: 0.0%
AST Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add AST to Watchlist:       View:      Get Complete AST Trend Analysis ➞

Stock Chart of Orchestra BioMed Holdings IncOBIO Orchestra BioMed Holdings Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 148.38 Millions
Recent Price: 2.46    
Market Intelligence Score: 10
Day Percent Change: -2.7668%    
Day Change: 0.06
Week Change: -9.22509%    
Year-to-date Change: -54.3%
OBIO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add OBIO to Watchlist:       View:      Get Complete OBIO Trend Analysis ➞

Stock Chart of Inovio Pharmaceuticals IncINO Inovio Pharmaceuticals Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 148.27 Millions
Recent Price: 2.18    
Market Intelligence Score: 30
Day Percent Change: -4.38596%    
Day Change: 0.06
Week Change: -20.7273%    
Year-to-date Change: 19.8%
INO Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add INO to Watchlist:       View:      Get Complete INO Trend Analysis ➞

Stock Chart of Achieve Life Sciences IncACHV Achieve Life Sciences Inc
Sector: Health Care
SubSector: Biotechnology
MarketCap: 144.63 Millions
Recent Price: 2.96    
Market Intelligence Score: 40
Day Percent Change: -3.8961%    
Day Change: 0.31
Week Change: -5.12821%    
Year-to-date Change: -19.8%
ACHV Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ACHV to Watchlist:       View:      Get Complete ACHV Trend Analysis ➞

Stock Chart of Nymox Pharmaceutical CorporationNYMX Nymox Pharmaceutical Corporation
Sector: Health Care
SubSector: Biotechnology
MarketCap: 143.585 Millions
Recent Price: 44.30    
Market Intelligence Score: 70
Day Percent Change: 0.158264%    
Day Change: -9999
Week Change: 8258.49%    
Year-to-date Change: 0.0%
NYMX Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add NYMX to Watchlist:       View:      Get Complete NYMX Trend Analysis ➞

Stock Chart of Zura Bio LtdZURA Zura Bio Ltd
Sector: Health Care
SubSector: Biotechnology
MarketCap: 143.04 Millions
Recent Price: 1.90    
Market Intelligence Score: 51
Day Percent Change: 13.71%    
Day Change: 0.24
Week Change: 15.7%    
Year-to-date Change: -20.4%
ZURA Links: Profile   News     Message Board
Charts:- Daily  , Weekly
Add ZURA to Watchlist:       View:      Get Complete ZURA Trend Analysis ➞

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Performance: Year-to-date, Week and Day
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